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The map label for this gene is sigZ

Identifier: 16079737

GI number: 16079737

Start: 2742244

End: 2742774

Strand: Reverse

Name: sigZ

Synonym: BSU26840

Alternate gene names: 16079737

Gene position: 2742774-2742244 (Counterclockwise)

Preceding gene: 16079739

Following gene: 16079736

Centisome position: 65.06

GC content: 38.42

Gene sequence:

>531_bases
ATGAATATAGAGGATCTATGGGATCAATTTCATCAGCCGTTAAAAACATATATTTCACATAGGGTTAACGATCAATCTAT
CGTTGATGACCTCTTGCAAATCGTATTTATGAAAATACAAGTGCATCTCCCAAATCTGATCGATGAACAAAAGATCGACA
GCTGGATTTATCGGATCACTAGAAATACGATTATTGATTTTTACCGTACAAAAAAAACAAGCGAAATATTGCCTGATGTT
CTACATTTTAATGACAGTGCAGAGGAAGAAAATTTCACCAAGGAAGCAACTGTGTGTATTCGATCGACCATCAAACGGTT
GCCTGAAAAGTATCGAGAGGCGCTCGAGTTAACTGATTTCCAGGGGTTATCACAAAAAGAGTTGAGTGAAAAGCTCGGCA
TTTCTTACTCCGGAGCAAAATCAAGGGTACAACGCGGACGTGGAAAATTAAAACAGCTGCTTGAGGGGTGCTGTCACATT
GAAGCGGATCGATATGGAAATATCGTAGACTTTCGTATTTTAAAGGAATAA

Upstream 100 bases:

>100_bases
AGCTGCAATACAATTGATTCAACAATTGTTTGCTCTTTGTTACGATTAAAAAGACGAAGCAAATGTAAAGCAGACGCAAA
ATTATAGGAGGTTTTTTCAA

Downstream 100 bases:

>100_bases
CTGATGAACATAGTCAGTTATTCCTTTAAAATAGGCCATCCGCATGAAGAGCATTTTTCCTTTGATGTTTGCAAGAGATG
TATGTATAATAAATCGTAAT

Product: RNA polymerase sigma factor SigZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRITRNTIIDFYRTKKTSEILPDV
LHFNDSAEEENFTKEATVCIRSTIKRLPEKYREALELTDFQGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHI
EADRYGNIVDFRILKE

Sequences:

>Translated_176_residues
MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRITRNTIIDFYRTKKTSEILPDV
LHFNDSAEEENFTKEATVCIRSTIKRLPEKYREALELTDFQGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHI
EADRYGNIVDFRILKE
>Mature_176_residues
MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRITRNTIIDFYRTKKTSEILPDV
LHFNDSAEEENFTKEATVCIRSTIKRLPEKYREALELTDFQGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHI
EADRYGNIVDFRILKE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SIGZ_BACSU (O05409)

Other databases:

- EMBL:   U93875
- EMBL:   AL009126
- PIR:   C69707
- RefSeq:   NP_390561.1
- ProteinModelPortal:   O05409
- SMR:   O05409
- EnsemblBacteria:   EBBACT00000001227
- GeneID:   937617
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU26840
- NMPDR:   fig|224308.1.peg.2686
- GenoList:   BSU26840
- GeneTree:   EBGT00070000031727
- HOGENOM:   HBG681240
- OMA:   EILIKTH
- ProtClustDB:   PRK09637
- BioCyc:   BSUB:BSU26840-MONOMER
- InterPro:   IPR014284
- InterPro:   IPR014304
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR02937
- TIGRFAMs:   TIGR02959

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2; SSF88946 Sigma_r2; SSF88659 Sigma_r3_r4

EC number: NA

Molecular weight: Translated: 20717; Mature: 20717

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRIT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RNTIIDFYRTKKTSEILPDVLHFNDSAEEENFTKEATVCIRSTIKRLPEKYREALELTDF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHIEADRYGNIVDFRILKE
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEHHEEECC
>Mature Secondary Structure
MNIEDLWDQFHQPLKTYISHRVNDQSIVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRIT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RNTIIDFYRTKKTSEILPDVLHFNDSAEEENFTKEATVCIRSTIKRLPEKYREALELTDF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHIEADRYGNIVDFRILKE
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377