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The map label for this gene is yqhB

Identifier: 16079531

GI number: 16079531

Start: 2561585

End: 2562913

Strand: Direct

Name: yqhB

Synonym: BSU24750

Alternate gene names: 16079531

Gene position: 2561585-2562913 (Clockwise)

Preceding gene: 16079521

Following gene: 16079534

Centisome position: 60.76

GC content: 40.86

Gene sequence:

>1329_bases
ATGCCTTCCTTGGAGAAGGCAGTTGTTTTGGAATTTATCAATTTACTAGCAGTCGCTATTCTCATTTTGTTAACAGGATT
TTTCGTTGCCGTAGAATTTTCAATCGTAAAAGTGCGGCGATCCAAAATTGATCAGCTTGTCGCAAAAGGAAAGAAAGGTG
CTAAAGCGGCAAAGCATGTCATCACTCACCTTGATGAATATTTATCAGCCTGTCAGCTGGGCATCACAGTCGCAGCTTTA
GGACTGGGATGGCTTGGGGAACCGACTGTGCAAACTCTGCTTCGACCGCTTTTTCATAAAGCAGGCTTAAATGAATCGCT
TACCCACCTGCTTTCACTCGTCATCGCATTTTTAGTGGTTACGTATTTAAATGTCGTTATTGGGGAGCTGGCGCCAAAGA
GTTTCGCCATTCAAAAAGCAGAAAGCATTACCTTGTTGTTCGCTAAACCGCTTATTTGGTTTTATAAGATCATGTTTCCA
TTCATTTGGCTGTTGAACCACTCTGCCCGATTGATTACAGGAGTGTTTGGGCTGAAGCCGGCATCAGAGCATGAGCTGGC
TTATACAGAGGAAGAACTTCGGGTCCTATTGGCTGAAAGCTATAAAAGCGGCGAGATCAGAAAAAGTGAATTAAAGTACA
TGAATAATATCTTCACCTTTGATAAACGAATGGCAAAGGAAATTATGGTGCCGCGAAATGAAATGGTTAGTTTGTCACTA
GATGAAGACTCCATTTCAAATCTTCAGGAAACAGTCAAGCAAACAAAATATACACGGTACCCGGTTGTAAGAGAGGATAA
AGATAACGTCATTGGCGTGATTAATATGAAAGAAGTGCTGTTTTCCATGCTGACGAAAGATTTTTCAATCAAGAAGCATC
AAATTGAACCTTTCGTACAGCCCGTTATCCATGTAATTGAGACGATTCCTATTTATAAACTATTGCTGAAAATGCAAAAG
GAACGCACTCATATGGCGATCCTCATAGATGAATATGGCGGGACGTCCGGTTTGGTCACTGTCGAGGATATTATCGAAGA
AATTGTAGGAGAAATCCGTGATGAATTTGATGCGGATGAAGTGCCTCATATCCGCGAACTTGGAAAGGATCATTACTTGT
TAAATGCAAAATTATTAATCAGCGATGTTAACAGCCTGCTTGGAACCGATTTATCAGAGGCTGAAGTAGACACCTTGGGC
GGCTGGTTTTTGACACAAAACATAGACGCTGAGCCTGAAAGTGCCATAGAATATGATGGCTACTCTTTTAAGGTAAAAGA
CATCAACAGCCATCACATTTTATTTATAGAAGTTAAAAAAGCTGAATAG

Upstream 100 bases:

>100_bases
CAATAACCGCGTCACTAAACCAGTCTGCCGCTTCAACACATGTTTTATGAGCATTTTCAGGTGGTATGGAATGTAGAAAG
ACATCGGAAAAGGGAGGTGC

Downstream 100 bases:

>100_bases
CCCGTGAAAGGCTGTTCAGCTGCTATCTTTCAAGATAAACATGGCAAAGGCATCAACACTCTTTTATTTTAAACCCTTTA
TTGGCCAGGGCTTTAGCAAG

Product: membrane associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKIDQLVAKGKKGAKAAKHVITHLDEYLSACQLGITVAAL
GLGWLGEPTVQTLLRPLFHKAGLNESLTHLLSLVIAFLVVTYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFP
FIWLLNHSARLITGVFGLKPASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIFTFDKRMAKEIMVPRNEMVSLSL
DEDSISNLQETVKQTKYTRYPVVREDKDNVIGVINMKEVLFSMLTKDFSIKKHQIEPFVQPVIHVIETIPIYKLLLKMQK
ERTHMAILIDEYGGTSGLVTVEDIIEEIVGEIRDEFDADEVPHIRELGKDHYLLNAKLLISDVNSLLGTDLSEAEVDTLG
GWFLTQNIDAEPESAIEYDGYSFKVKDINSHHILFIEVKKAE

Sequences:

>Translated_442_residues
MPSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKIDQLVAKGKKGAKAAKHVITHLDEYLSACQLGITVAAL
GLGWLGEPTVQTLLRPLFHKAGLNESLTHLLSLVIAFLVVTYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFP
FIWLLNHSARLITGVFGLKPASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIFTFDKRMAKEIMVPRNEMVSLSL
DEDSISNLQETVKQTKYTRYPVVREDKDNVIGVINMKEVLFSMLTKDFSIKKHQIEPFVQPVIHVIETIPIYKLLLKMQK
ERTHMAILIDEYGGTSGLVTVEDIIEEIVGEIRDEFDADEVPHIRELGKDHYLLNAKLLISDVNSLLGTDLSEAEVDTLG
GWFLTQNIDAEPESAIEYDGYSFKVKDINSHHILFIEVKKAE
>Mature_441_residues
PSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKIDQLVAKGKKGAKAAKHVITHLDEYLSACQLGITVAALG
LGWLGEPTVQTLLRPLFHKAGLNESLTHLLSLVIAFLVVTYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFPF
IWLLNHSARLITGVFGLKPASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIFTFDKRMAKEIMVPRNEMVSLSLD
EDSISNLQETVKQTKYTRYPVVREDKDNVIGVINMKEVLFSMLTKDFSIKKHQIEPFVQPVIHVIETIPIYKLLLKMQKE
RTHMAILIDEYGGTSGLVTVEDIIEEIVGEIRDEFDADEVPHIRELGKDHYLLNAKLLISDVNSLLGTDLSEAEVDTLGG
WFLTQNIDAEPESAIEYDGYSFKVKDINSHHILFIEVKKAE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=408, Percent_Identity=47.7941176470588, Blast_Score=386, Evalue=1e-107,
Organism=Escherichia coli, GI1790664, Length=424, Percent_Identity=22.1698113207547, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786879, Length=260, Percent_Identity=32.3076923076923, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI145693175, Length=379, Percent_Identity=22.6912928759894, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082033, Length=266, Percent_Identity=22.9323308270677, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788119, Length=161, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YQHB_BACSU (P54505)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   E69958
- RefSeq:   NP_390355.1
- ProteinModelPortal:   P54505
- SMR:   P54505
- EnsemblBacteria:   EBBACT00000003294
- GeneID:   938492
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU24750
- NMPDR:   fig|224308.1.peg.2479
- GenoList:   BSU24750
- GeneTree:   EBGT00070000032069
- HOGENOM:   HBG673071
- OMA:   WIGESTM
- PhylomeDB:   P54505
- ProtClustDB:   CLSK887568
- BioCyc:   BSUB:BSU24750-MONOMER
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 49957; Mature: 49826

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10c7f434)-; HASH(0x10b011f8)-; HASH(0x10deb7bc)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKIDQLVAKGKKGAKAAKHV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ITHLDEYLSACQLGITVAALGLGWLGEPTVQTLLRPLFHKAGLNESLTHLLSLVIAFLVV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFPFIWLLNHSARLITGVFGLKP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
ASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIFTFDKRMAKEIMVPRNEMVSLSL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DEDSISNLQETVKQTKYTRYPVVREDKDNVIGVINMKEVLFSMLTKDFSIKKHQIEPFVQ
CHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHCCCCCHHHCCHHHH
PVIHVIETIPIYKLLLKMQKERTHMAILIDEYGGTSGLVTVEDIIEEIVGEIRDEFDADE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCC
VPHIRELGKDHYLLNAKLLISDVNSLLGTDLSEAEVDTLGGWFLTQNIDAEPESAIEYDG
CCHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCCCEECCC
YSFKVKDINSHHILFIEVKKAE
EEEEEEECCCCEEEEEEEECCH
>Mature Secondary Structure 
PSLEKAVVLEFINLLAVAILILLTGFFVAVEFSIVKVRRSKIDQLVAKGKKGAKAAKHV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ITHLDEYLSACQLGITVAALGLGWLGEPTVQTLLRPLFHKAGLNESLTHLLSLVIAFLVV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TYLNVVIGELAPKSFAIQKAESITLLFAKPLIWFYKIMFPFIWLLNHSARLITGVFGLKP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
ASEHELAYTEEELRVLLAESYKSGEIRKSELKYMNNIFTFDKRMAKEIMVPRNEMVSLSL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DEDSISNLQETVKQTKYTRYPVVREDKDNVIGVINMKEVLFSMLTKDFSIKKHQIEPFVQ
CHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHCCCCCHHHCCHHHH
PVIHVIETIPIYKLLLKMQKERTHMAILIDEYGGTSGLVTVEDIIEEIVGEIRDEFDADE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCC
VPHIRELGKDHYLLNAKLLISDVNSLLGTDLSEAEVDTLGGWFLTQNIDAEPESAIEYDG
CCHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCCCEECCC
YSFKVKDINSHHILFIEVKKAE
EEEEEEECCCCEEEEEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377