Click here to switch to the map view.

The map label for this gene is sipW

Identifier: 16079519

GI number: 16079519

Start: 2553930

End: 2554502

Strand: Reverse

Name: sipW

Synonym: BSU24630

Alternate gene names: 16079519

Gene position: 2554502-2553930 (Counterclockwise)

Preceding gene: 16079520

Following gene: 16079518

Centisome position: 60.6

GC content: 42.41

Gene sequence:

>573_bases
ATGAAGCTGATCAGTAATATTTTATACGTGATCATCTTTACTCTTATTATTGTGCTGACACTTGTCGTGATTTCAACACG
TTCATCCGGGGGAGAGCCGGCAGTGTTTGGGTATACGCTGAAATCAGTTCTGTCAGGTTCGATGGAGCCGGAGTTCAATA
CAGGTTCCTTAATATTGGTCAAAGAAATCACTGATGTGAAAGAGCTCCAAAAAGGTGACGTTATTACATTTATGCAGGAT
GCAAATACGGCGGTCACCCACAGAATTGTTGACATAACAAAGCAAGGAGACCATTTGTTATTTAAAACAAAAGGTGATAA
TAATGCAGCAGCTGATTCAGCGCCTGTATCGGACGAAAATGTTCGCGCGCAATACACAGGTTTTCAGCTTCCATATGCCG
GCTATATGCTTCATTTTGCCAGCCAGCCGATTGGAACGGCTGTATTATTGATTGTTCCCGGCGTGATGCTGTTAGTTTAC
GCTTTTGTGACGATCAGCAGCGCCATTAGAGAAATTGAAAGAAAGACAAAAGCCTTGGAAACAGATACAAAGGACAGCAC
CATGTCTACTTAA

Upstream 100 bases:

>100_bases
GAAAAAACAATGAAAGAAGAAACATCTCAAGAAGCTGTAACCAAAGAAAAAGAAACTCAATCAGACCAGAAGGAAAGCGG
GGAAGAGGATGAAAAAAGCA

Downstream 100 bases:

>100_bases
CTTCAGTTGTAAACCTGGCAACAGGTTTCGATATAAAATCATTCAATAAAAGGGGAGCTTACCATGGGTATGAAAAAGAA
ATTGAGTTTAGGAGTTGCTT

Product: type I signal peptidase

Products: NA

Alternate protein names: SPase I; Leader peptidase I

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVLSGSMEPEFNTGSLILVKEITDVKELQKGDVITFMQD
ANTAVTHRIVDITKQGDHLLFKTKGDNNAAADSAPVSDENVRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVY
AFVTISSAIREIERKTKALETDTKDSTMST

Sequences:

>Translated_190_residues
MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVLSGSMEPEFNTGSLILVKEITDVKELQKGDVITFMQD
ANTAVTHRIVDITKQGDHLLFKTKGDNNAAADSAPVSDENVRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVY
AFVTISSAIREIERKTKALETDTKDSTMST
>Mature_190_residues
MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVLSGSMEPEFNTGSLILVKEITDVKELQKGDVITFMQD
ANTAVTHRIVDITKQGDHLLFKTKGDNNAAADSAPVSDENVRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVY
AFVTISSAIREIERKTKALETDTKDSTMST

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26B family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LEPW_BACSU (P54506)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   B69708
- RefSeq:   NP_390343.1
- ProteinModelPortal:   P54506
- SMR:   P54506
- MEROPS:   S26.011
- EnsemblBacteria:   EBBACT00000000313
- GeneID:   938542
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU24630
- NMPDR:   fig|224308.1.peg.2467
- GenoList:   BSU24630
- GeneTree:   EBGT00050000002288
- HOGENOM:   HBG338175
- OMA:   VITHRIT
- ProtClustDB:   CLSK2752447
- BioCyc:   BSUB:BSU24630-MONOMER
- BRENDA:   3.4.21.89
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR001733
- Gene3D:   G3DSA:2.10.109.10
- PANTHER:   PTHR10806
- PRINTS:   PR00728
- TIGRFAMs:   TIGR02228

Pfam domain/function: PF00717 Peptidase_S24; SSF51306 Pept_S24_S26_C

EC number: =3.4.21.89

Molecular weight: Translated: 20678; Mature: 20678

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: ACT_SITE 45-45

Signals:

None

Transmembrane regions:

HASH(0x108d48f8)-; HASH(0x10d5974c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVLSGSMEPEFNTGSLILV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
KEITDVKELQKGDVITFMQDANTAVTHRIVDITKQGDHLLFKTKGDNNAAADSAPVSDEN
ECHHHHHHHCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCCC
VRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVYAFVTISSAIREIERKTKALE
CEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDTKDSTMST
CCCCCCCCCH
>Mature Secondary Structure
MKLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFGYTLKSVLSGSMEPEFNTGSLILV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
KEITDVKELQKGDVITFMQDANTAVTHRIVDITKQGDHLLFKTKGDNNAAADSAPVSDEN
ECHHHHHHHCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCCC
VRAQYTGFQLPYAGYMLHFASQPIGTAVLLIVPGVMLLVYAFVTISSAIREIERKTKALE
CEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDTKDSTMST
CCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9823656