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The map label for this gene is yqhT

Identifier: 16079502

GI number: 16079502

Start: 2538697

End: 2539758

Strand: Reverse

Name: yqhT

Synonym: BSU24460

Alternate gene names: 16079502

Gene position: 2539758-2538697 (Counterclockwise)

Preceding gene: 16079503

Following gene: 255767547

Centisome position: 60.25

GC content: 46.99

Gene sequence:

>1062_bases
ATGAAGCTAGAGAAATTAAGAAACCTGTTTGGACAGCTGGGAATTGACGGCATGCTGATTACAAGCAACACTAATGTACG
CTATATGACAGGGTTTACAGGTTCGGCGGGTTTGGCTGTTATATCGGGTGACAAAGCAGCGTTTATTACGGATTTTCGTT
ATACTGAGCAGGCGAAGGTTCAGGTAAAGGGTTTTGAGATCATTGAACATGGCGGCAGCTTGATTCAGACCACTGCCGAC
ACTGTTGAATCGTTTGGCATCAAGCGTCTCGGCTTTGAACAGAACAGCATGACATATGGCACTTACGCTTCATACAGCGC
CGTTATCAGTGATGCCGAATTAGTGCCTGTGGCTGAATCCGTGGAAAAGTTGCGCTTGATTAAGTCTAGTGAAGAGATTA
AGATATTAGAGGAAGCTGCGAAGATTGCAGATGATGCCTTCAGACATATCTTGACGTTTATGAAACCCGGCATTTCTGAA
ATCGCTGTTGCCAATGAGCTGGAGTTTTATATGAGAAGCCAGGGAGCAGACAGCTCTTCTTTTGATATGATTGTCGCCTC
AGGCCTTCGTTCAAGCCTTCCGCACGGTGTGGCCAGTGACAAACTGATTGAAAGCGGAGACCTTGTTACGCTTGATTTTG
GCGCTTATTATAAAGGATATTGTTCTGATATTACCCGGACGGTCGCTGTAGGTCAGCCCAGTGATCAATTGAAGGAGATC
TATCAGGTTGTATTTGATGCTCAGGCGCTTGGCGTCGCACATATTAAGCCGGGAATGACAGGAAAAGAGGCTGACGCCCT
CACAAGGGATCATATTGCTGCAAAAGGCTACGGTGACTATTTCGGCCATTCAACCGGGCACGGGCTCGGCATGGAAGTTC
ATGAATCGCCGGGATTATCCGTCAGATCTTCAGCTATCCTTGAACCGGGTATGGTGGTCACAGTGGAGCCGGGCATTTAC
ATACCAGAAACAGGCGGTGTCCGCATTGAAGATGACATCGTGATTACAGAAAACGGCAACCGGACAATCACCCATTCCCC
AAAAGAACTTATTATTTTGTGA

Upstream 100 bases:

>100_bases
TTATCGCTCCTGTTGCGAAAGGGCAGATTGTCGGTCTTGGAGCTGAAGGCTACAAGCTTGCTGTTCGCTACTTATTAAGC
CAGCAAGGGGGAGAATCAAG

Downstream 100 bases:

>100_bases
TTGGAATATAGGAGGACATTAAACATGATTTCAGTTAACGATTTCCGTACAGGATTAACAATTGAAGTAGATGGCGGCAT
TTGGCGCGTCGTTGACTTCC

Product: aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKVQVKGFEIIEHGGSLIQTTAD
TVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISE
IAVANELEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEI
YQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLSVRSSAILEPGMVVTVEPGIY
IPETGGVRIEDDIVITENGNRTITHSPKELIIL

Sequences:

>Translated_353_residues
MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKVQVKGFEIIEHGGSLIQTTAD
TVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISE
IAVANELEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEI
YQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLSVRSSAILEPGMVVTVEPGIY
IPETGGVRIEDDIVITENGNRTITHSPKELIIL
>Mature_353_residues
MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKVQVKGFEIIEHGGSLIQTTAD
TVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISE
IAVANELEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEI
YQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLSVRSSAILEPGMVVTVEPGIY
IPETGGVRIEDDIVITENGNRTITHSPKELIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family

Homologues:

Organism=Homo sapiens, GI11559925, Length=263, Percent_Identity=34.9809885931559, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI260593665, Length=293, Percent_Identity=27.9863481228669, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI149589008, Length=293, Percent_Identity=27.9863481228669, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI260593663, Length=264, Percent_Identity=28.4090909090909, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI264681563, Length=215, Percent_Identity=32.093023255814, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI93141226, Length=254, Percent_Identity=28.740157480315, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI164420681, Length=227, Percent_Identity=22.9074889867841, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI264681565, Length=212, Percent_Identity=30.6603773584906, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788728, Length=357, Percent_Identity=39.7759103641457, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1789275, Length=279, Percent_Identity=33.6917562724014, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786364, Length=204, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790282, Length=293, Percent_Identity=26.2798634812287, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508215, Length=306, Percent_Identity=27.4509803921569, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17509539, Length=186, Percent_Identity=33.8709677419355, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=233, Percent_Identity=24.4635193133047, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320922, Length=260, Percent_Identity=27.3076923076923, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6321118, Length=284, Percent_Identity=27.112676056338, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323273, Length=206, Percent_Identity=26.2135922330097, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322999, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920384, Length=289, Percent_Identity=30.7958477508651, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21357079, Length=312, Percent_Identity=30.1282051282051, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355531, Length=146, Percent_Identity=23.972602739726, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YQHT_BACSU (P54518)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   C69960
- RefSeq:   NP_390326.1
- ProteinModelPortal:   P54518
- SMR:   P54518
- MEROPS:   M24.008
- EnsemblBacteria:   EBBACT00000000156
- GeneID:   938560
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU24460
- NMPDR:   fig|224308.1.peg.2450
- GenoList:   BSU24460
- GeneTree:   EBGT00070000031884
- HOGENOM:   HBG545079
- OMA:   EYILTVA
- PhylomeDB:   P54518
- ProtClustDB:   CLSK887552
- BioCyc:   BSUB:BSU24460-MONOMER
- GO:   GO:0006508
- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131
- Gene3D:   G3DSA:3.90.230.10
- PANTHER:   PTHR10804
- PRINTS:   PR00599

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24; SSF55920 Peptidase_M24_cat_core

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38121; Mature: 38121

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKV
CCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCEEEEECCCEEEEEEEEECCCEEE
QVKGFEIIEHGGSLIQTTADTVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAES
EEECEEEECCCCCEEEHHHHHHHHCCCHHCCCCCCCEEECCCHHHHHHHCCCCEECHHHH
VEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISEIAVANELEFYMRSQGADSSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
FDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEI
HHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCHHHHHHHHHHHEEECCCCHHHHHHH
YQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLS
HHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEECCCCCC
VRSSAILEPGMVVTVEPGIYIPETGGVRIEDDIVITENGNRTITHSPKELIIL
CCHHHCCCCCEEEEECCCEEECCCCCEEEECCEEEECCCCEEEEECCCEEEEC
>Mature Secondary Structure
MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKV
CCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCEEEEECCCEEEEEEEEECCCEEE
QVKGFEIIEHGGSLIQTTADTVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAES
EEECEEEECCCCCEEEHHHHHHHHCCCHHCCCCCCCEEECCCHHHHHHHCCCCEECHHHH
VEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISEIAVANELEFYMRSQGADSSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
FDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEI
HHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCHHHHHHHHHHHEEECCCCHHHHHHH
YQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLS
HHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEECCCCCC
VRSSAILEPGMVVTVEPGIYIPETGGVRIEDDIVITENGNRTITHSPKELIIL
CCHHHCCCCCEEEEECCCEEECCCCCEEEECCEEEECCCCEEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377