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The map label for this gene is aroD

Identifier: 16079365

GI number: 16079365

Start: 2412706

End: 2413473

Strand: Reverse

Name: aroD

Synonym: BSU23080

Alternate gene names: 16079365

Gene position: 2413473-2412706 (Counterclockwise)

Preceding gene: 255767496

Following gene: 16079363

Centisome position: 57.25

GC content: 42.84

Gene sequence:

>768_bases
GTGAACGTGTTAACGATTAAAGGAGTTTCCATCGGGGAAGGGATGCCGAAAATCATCATTCCGCTGATGGGAAAGACGGA
AAAACAAATTCTGAATGAAGCAGAGGCAGTAAAATTACTGAATCCGGACATTGTTGAATGGAGAGTCGACGTATTTGAAA
AAGCGAATGACAGAGAAGCGGTCACAAAGCTCATTTCTAAGCTTCGTAAATCTTTAGAAGACAAGCTATTTCTATTTACA
TTCAGAACCCACAAAGAGGGCGGGAGCATGGAGATGGACGAAAGCTCCTATCTTGCTTTGCTGGAATCGGCAATCCAAAC
AAAAGACATCGATCTGATAGACATCGAATTATTTTCAGGAGATGCAAATGTAAAAGCGTTAGTATCGCTGGCGGAAGAAA
ACAACGTCTATGTGGTGATGTCAAATCACGACTTTGAAAAAACACCTGTAAAAGATGAAATTATTTCCAGACTTCGAAAA
ATGCAGGACTTAGGCGCGCATATTCCAAAAATGGCTGTCATGCCGAATGATACTGGAGATCTCCTAACACTGCTTGATGC
GACGTATACAATGAAAACAATATATGCAGACCGCCCCATTATTACAATGTCAATGGCTGCAACAGGGCTCATCAGCAGGC
TGAGCGGTGAGGTTTTTGGATCGGCTTGTACTTTTGGAGCTGGAGAAGAGGCGTCCGCACCAGGCCAAATTCCTGTTTCT
GAGCTAAGGAGTGTCTTAGATATTTTGCATAAAAACACACGGGGATAG

Upstream 100 bases:

>100_bases
TAAGGCTCTTTTTTAGTTGCTATTCATATAATAGAAATTTTCAAAAAAAAGTTGTACGTGTATAATAAAACAAGGTAAAG
ATTGAAAGGATTTGAGACGA

Downstream 100 bases:

>100_bases
AACAATAAAAAAACTCAAGCTATATAGCTTGAGTTTTTTTAATTATGGCAGATCAATGAGCTTCACAGACACAATATCAG
GGACATTTGTTAGTTCTTTC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNVLTIKGVSIGEGMPKIIIPLMGKTEKQILNEAEAVKLLNPDIVEWRVDVFEKANDREAVTKLISKLRKSLEDKLFLFT
FRTHKEGGSMEMDESSYLALLESAIQTKDIDLIDIELFSGDANVKALVSLAEENNVYVVMSNHDFEKTPVKDEIISRLRK
MQDLGAHIPKMAVMPNDTGDLLTLLDATYTMKTIYADRPIITMSMAATGLISRLSGEVFGSACTFGAGEEASAPGQIPVS
ELRSVLDILHKNTRG

Sequences:

>Translated_255_residues
MNVLTIKGVSIGEGMPKIIIPLMGKTEKQILNEAEAVKLLNPDIVEWRVDVFEKANDREAVTKLISKLRKSLEDKLFLFT
FRTHKEGGSMEMDESSYLALLESAIQTKDIDLIDIELFSGDANVKALVSLAEENNVYVVMSNHDFEKTPVKDEIISRLRK
MQDLGAHIPKMAVMPNDTGDLLTLLDATYTMKTIYADRPIITMSMAATGLISRLSGEVFGSACTFGAGEEASAPGQIPVS
ELRSVLDILHKNTRG
>Mature_255_residues
MNVLTIKGVSIGEGMPKIIIPLMGKTEKQILNEAEAVKLLNPDIVEWRVDVFEKANDREAVTKLISKLRKSLEDKLFLFT
FRTHKEGGSMEMDESSYLALLESAIQTKDIDLIDIELFSGDANVKALVSLAEENNVYVVMSNHDFEKTPVKDEIISRLRK
MQDLGAHIPKMAVMPNDTGDLLTLLDATYTMKTIYADRPIITMSMAATGLISRLSGEVFGSACTFGAGEEASAPGQIPVS
ELRSVLDILHKNTRG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=251, Percent_Identity=53.7848605577689, Blast_Score=267, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_BACSU (P35146)

Other databases:

- EMBL:   L09228
- EMBL:   AL009126
- PIR:   S45563
- RefSeq:   NP_390189.1
- ProteinModelPortal:   P35146
- SMR:   P35146
- EnsemblBacteria:   EBBACT00000000988
- GeneID:   938963
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU23080
- NMPDR:   fig|224308.1.peg.2312
- GenoList:   BSU23080
- GeneTree:   EBGT00050000001972
- HOGENOM:   HBG732926
- OMA:   NHDFDKT
- PhylomeDB:   P35146
- ProtClustDB:   PRK02412
- BioCyc:   BSUB:BSU23080-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00214
- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 28132; Mature: 28132

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 143-143 ACT_SITE 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLTIKGVSIGEGMPKIIIPLMGKTEKQILNEAEAVKLLNPDIVEWRVDVFEKANDREA
CCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
VTKLISKLRKSLEDKLFLFTFRTHKEGGSMEMDESSYLALLESAIQTKDIDLIDIELFSG
HHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECC
DANVKALVSLAEENNVYVVMSNHDFEKTPVKDEIISRLRKMQDLGAHIPKMAVMPNDTGD
CCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCH
LLTLLDATYTMKTIYADRPIITMSMAATGLISRLSGEVFGSACTFGAGEEASAPGQIPVS
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
ELRSVLDILHKNTRG
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MNVLTIKGVSIGEGMPKIIIPLMGKTEKQILNEAEAVKLLNPDIVEWRVDVFEKANDREA
CCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
VTKLISKLRKSLEDKLFLFTFRTHKEGGSMEMDESSYLALLESAIQTKDIDLIDIELFSG
HHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECC
DANVKALVSLAEENNVYVVMSNHDFEKTPVKDEIISRLRKMQDLGAHIPKMAVMPNDTGD
CCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCH
LLTLLDATYTMKTIYADRPIITMSMAATGLISRLSGEVFGSACTFGAGEEASAPGQIPVS
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
ELRSVLDILHKNTRG
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377