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The map label for this gene is engA

Identifier: 16079341

GI number: 16079341

Start: 2390206

End: 2391516

Strand: Reverse

Name: engA

Synonym: BSU22840

Alternate gene names: 16079341

Gene position: 2391516-2390206 (Counterclockwise)

Preceding gene: 255767490

Following gene: 16079340

Centisome position: 56.73

GC content: 43.71

Gene sequence:

>1311_bases
ATGGGTAAACCTGTCGTAGCCATTGTCGGGAGACCAAATGTAGGAAAATCCACAATCTTTAACCGGATTGCGGGAGAAAG
AATTTCAATAGTAGAAGATACCCCTGGCGTGACAAGGGATCGGATATACAGCTCGGCTGAATGGCTGAATTATGATTTTA
ATTTGATTGATACGGGCGGTATTGATATCGGTGATGAGCCGTTTTTAGCGCAGATTCGCCAGCAAGCTGAAATCGCCATG
GATGAAGCGGACGTGATTATTTTTATGGTGAACGGCCGTGAAGGCGTGACAGCTGCTGATGAAGAAGTGGCGAAAATTTT
GTACCGCACAAAAAAGCCTGTTGTTTTAGCGGTTAATAAACTGGATAACACAGAAATGAGAGCGAATATTTATGATTTTT
ATTCGCTAGGCTTTGGCGAGCCGTATCCAATTTCGGGAACACACGGACTCGGACTGGGTGATTTACTGGATGCCGTTGCA
GAGCATTTTAAAAACATTCCTGAAACGAAATACAATGAAGAAGTTATTCAATTCTGTCTGATCGGACGTCCAAATGTCGG
AAAGTCTTCACTTGTGAATGCGATGCTCGGCGAAGAACGCGTTATTGTCAGCAACGTGGCTGGAACGACAAGAGATGCTG
TTGATACGTCATTTACTTACAACCAGCAGGAGTTTGTCATTGTCGATACTGCAGGTATGCGAAAAAAAGGGAAAGTCTAT
GAAACGACTGAGAAGTATAGTGTACTGCGGGCGCTAAAAGCGATTGACCGCTCAGAAGTCGTGGCGGTTGTGCTGGATGG
CGAAGAAGGCATTATTGAACAGGACAAGCGTATCGCCGGTTATGCACACGAAGCGGGCAAGGCCGTCGTCATCGTCGTAA
ACAAATGGGATGCTGTTGACAAAGATGAGAGCACGATGAAAGAATTTGAAGAAAATATTCGCGATCATTTTCAATTTCTG
GATTATGCGCCAATCCTATTTATGTCTGCCTTAACGAAAAAACGGATCCATACTCTGATGCCTGCGATTATCAAAGCTAG
TGAAAATCATTCACTTCGAGTTCAAACAAACGTCTTAAATGATGTCATCATGGACGCTGTGGCAATGAATCCGACACCGA
CTCATAACGGTTCTCGTTTGAAAATTTACTATGCGACTCAAGTGTCGGTAAAGCCGCCAAGCTTCGTTGTGTTTGTAAAC
GATCCGGAACTGATGCATTTTTCATACGAACGGTTTTTAGAAAACCGAATCAGAGACGCGTTCGGTTTTGAGGGGACACC
AATCAAAATATTTGCAAGAGCTAGAAAATAA

Upstream 100 bases:

>100_bases
TCTGAAGGGTTTCTTTTCATAAAAGTGAATGAAATGATTTTAATAACCGGTTGAAAATTTATGTAAAAATGAAAGCGGCT
GGATTGAAAGGAAGGGTACT

Downstream 100 bases:

>100_bases
AAAGGTGTGAATCAAACATGAAAAAAGTCACAATGCTTGGAGCGGGGAGTTGGGGAACAGCACTGGCTTTAGTTCTAACT
GATAATGGAAATGAAGTGTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAM
DEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVA
EHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVY
ETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFL
DYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVN
DPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK

Sequences:

>Translated_436_residues
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAM
DEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVA
EHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVY
ETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFL
DYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVN
DPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK
>Mature_435_residues
GKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMD
EADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAE
HFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVYE
TTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLD
YAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVND
PELMHFSYERFLENRIRDAFGFEGTPIKIFARARK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=38.2417582417582, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1788919, Length=173, Percent_Identity=32.9479768786127, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=37.2340425531915, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=206, Percent_Identity=30.0970873786408, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550813, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48770; Mature: 48639

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHEECCEEEEECCC
IDIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEC
LDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQFCL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVY
CCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCCEEECCCEEEEEECCCCCCCCCEE
ETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVD
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHCCHHCCCCEEEEEEECCCCCC
KDESTMKEFEENIRDHFQFLDYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FGFEGTPIKIFARARK
HCCCCCCEEEEEECCC
>Mature Secondary Structure 
GKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGG
CCCEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHEECCEEEEECCC
IDIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEC
LDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQFCL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVY
CCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCCEEECCCEEEEEECCCCCCCCCEE
ETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVD
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHCCHHCCCCEEEEEEECCCCCC
KDESTMKEFEENIRDHFQFLDYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FGFEGTPIKIFARARK
HCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA