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The map label for this gene is kdgR

Identifier: 16079270

GI number: 16079270

Start: 2324613

End: 2325632

Strand: Reverse

Name: kdgR

Synonym: BSU22120

Alternate gene names: 16079270

Gene position: 2325632-2324613 (Counterclockwise)

Preceding gene: 16079273

Following gene: 16079269

Centisome position: 55.17

GC content: 43.43

Gene sequence:

>1020_bases
ATGAAAAAGAAAACAACAGGCCATACAACCATCAAAGACGTAGCTGAATGTGCAGGAGTTTCGAAATCGACAGTTTCCCG
CTATATTAACGGAAAAATTGACGCGATTTCTCCTGAAAAAGTGAAAAACATTAAAAAGGCAATCGCAGAATTGAATTATC
GGCCGAGTAAAATGGCACAAGGTTTGAAAATAAAAAAAAGCAAGTTAATCGGATTTGTTGTGGCTGACATTACAAATCCT
TTTTCGGTCGCTGCTTTCAGGGGAGTCGAAGAGGTTTGTGATCAATATGGATACAGCATTATGGTGTGCAACACAGATAA
CAGTCCTGAAAAAGAGCGGGAAATGCTCTTAAAGCTAGAAGCCCATTCGGTTGAGGGCTTGATTTTAAACGCAACAGGGG
AAAACAAGGATGTACTCCGCGCTTTTGCTGAACAGCAAATTCCAACAATCTTAATTGACCGGAAACTGCCGGATCTGAAA
CTGGATACCGTAACGACTGACAACAGATGGATCACAAAAGAGATTCTTCAGAAGGTGTACAGCAAAGGGTATACTGATGT
CGCGCTGTTTACCGAACCGATTTCCTCTATCAGCCCTCGTGCAGAAAGAGCAGCTGTGTATCAGGAAATGGCTTCGGTTC
AAAATGTGAACGGGCTTGTCAGATTGCATGAAATTGACGTAAAGGACAAGGAGCAGCTTAAGGCGGAGCTTCGTTCTTTT
CACAAGGAAATGCCGGAGCAAAAAAAAGCGATTCTGGCTTTGAATGGCTTGATTATGCTGAAAATCATCAGCTGTATGGA
AGAGCTTGGCCTGCGCATCCCTCAAGATATAGGGATTGCAGGATTCGATGATACGGAGTGGTACAAACTGATCGGTCCAG
GCATTACAACGATCGCCCAGCCGTCACATGATATGGGCAGGACGGCGATGGAACGTGTATTAAAAAGGATTGAAGGTGAC
AAAGGAGCGCCTCAAACCATTGAATTAGAGGCAAAAGTCATCATGAGAAAGTCACTTTAA

Upstream 100 bases:

>100_bases
ATTATTAAAAAAACTCTTCCCAAATTTTAAAATTATGGTATTCTTTTGTTGTAACGGTTTTGAAATCGGTTTCAAATATA
TGAGATACAGGAGCACTTGA

Downstream 100 bases:

>100_bases
TCCTAGGTGCCCTCAACTAAGAGGAGGTTGGGAAGAGATGAAGCTTGATGCGGTGACATTCGGGGAATCAATGGCCATGT
TTTATGCAAATGAGTATGGA

Product: Kdg operon transcriptional regulator

Products: NA

Alternate protein names: Kdg operon repressor

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKKSKLIGFVVADITNP
FSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLK
LDTVTTDNRWITKEILQKVYSKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSF
HKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDMGRTAMERVLKRIEGD
KGAPQTIELEAKVIMRKSL

Sequences:

>Translated_339_residues
MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKKSKLIGFVVADITNP
FSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLK
LDTVTTDNRWITKEILQKVYSKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSF
HKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDMGRTAMERVLKRIEGD
KGAPQTIELEAKVIMRKSL
>Mature_339_residues
MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKKSKLIGFVVADITNP
FSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLK
LDTVTTDNRWITKEILQKVYSKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSF
HKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDMGRTAMERVLKRIEGD
KGAPQTIELEAKVIMRKSL

Specific function: Transcriptional repressor of the kdg operon for pectin utilization

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790194, Length=337, Percent_Identity=29.673590504451, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787948, Length=336, Percent_Identity=26.1904761904762, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI48994940, Length=338, Percent_Identity=26.3313609467456, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=24.8538011695906, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786540, Length=317, Percent_Identity=27.7602523659306, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=27.0903010033445, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788474, Length=314, Percent_Identity=26.7515923566879, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787580, Length=342, Percent_Identity=23.6842105263158, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790715, Length=337, Percent_Identity=23.7388724035608, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787906, Length=350, Percent_Identity=24.8571428571429, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789068, Length=339, Percent_Identity=24.188790560472, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786268, Length=315, Percent_Identity=21.5873015873016, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790689, Length=326, Percent_Identity=22.0858895705521, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGR_BACSU (P50844)

Other databases:

- EMBL:   L47838
- EMBL:   AL009126
- PIR:   B69648
- RefSeq:   NP_390094.1
- ProteinModelPortal:   P50844
- SMR:   P50844
- EnsemblBacteria:   EBBACT00000002922
- GeneID:   939063
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU22120
- NMPDR:   fig|224308.1.peg.2217
- GenoList:   BSU22120
- GeneTree:   EBGT00070000031749
- HOGENOM:   HBG753640
- OMA:   SIMVCNT
- ProtClustDB:   CLSK887482
- BioCyc:   BSUB:BSU22120-MONOMER
- GO:   GO:0005622
- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- PRINTS:   PR00036
- SMART:   SM00354

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1; SSF47413 Lambda_like_DNA

EC number: NA

Molecular weight: Translated: 37859; Mature: 37859

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00356 HTH_LACI_1; PS50932 HTH_LACI_2; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQ
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GLKIKKSKLIGFVVADITNPFSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLE
CCHHHHHHHHEEHEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHH
AHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLKLDTVTTDNRWITKEILQKVY
CCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHH
SKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSF
HCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
HKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHCC
PSHDMGRTAMERVLKRIEGDKGAPQTIELEAKVIMRKSL
CCHHCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCC
>Mature Secondary Structure
MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQ
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GLKIKKSKLIGFVVADITNPFSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLE
CCHHHHHHHHEEHEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHH
AHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLKLDTVTTDNRWITKEILQKVY
CCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHH
SKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSF
HCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
HKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHCC
PSHDMGRTAMERVLKRIEGDKGAPQTIELEAKVIMRKSL
CCHHCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377