Click here to switch to the map view.

The map label for this gene is kdgK

Identifier: 16079269

GI number: 16079269

Start: 2323601

End: 2324575

Strand: Reverse

Name: kdgK

Synonym: BSU22110

Alternate gene names: 16079269

Gene position: 2324575-2323601 (Counterclockwise)

Preceding gene: 16079270

Following gene: 16079268

Centisome position: 55.14

GC content: 48.1

Gene sequence:

>975_bases
ATGAAGCTTGATGCGGTGACATTCGGGGAATCAATGGCCATGTTTTATGCAAATGAGTATGGAGGCCTTCATGAAGTATC
CACTTTTTCTAAAGGGCTTGCCGGAGCAGAAAGCAATGTCGCCTGCGGCCTTGCCAGACTCGGATTTCGAATGGGATGGA
TGAGCAAGGTCGGCAATGATCAGCTCGGAACGTTTATTTTACAAGAGCTTAAAAAAGAGGGAGTGGATGTGTCCCGCGTG
ATCCGCTCGCAGGACGAAAATCCCACCGGGCTGCTGCTGAAGTCAAAAGTGAAAGAAGGCGACCCGCAAGTTACCTACTA
TAGGAAAAACTCAGCTGCAAGCACATTAACTACAGCTGAATATCCGAGAGATTATTTTCAATGCGCAGGCCATTTGCATG
TGACAGGTATTCCGCCTGCTTTATCAGCCGAGATGAAAGACTTCACGTATCATGTCATGAACGACATGAGAAACGCAGGG
AAGACCATTTCATTCGACCCTAATGTAAGACCTTCGCTTTGGCCTGATCAAGCAACAATGGTACACACAATCAATGATCT
GGCTGGGCTTGCAGACTGGTTTTTCCCGGGTATCGCAGAGGGAGAGCTATTGACCGGAGAAAAAACACCTGAAGGCATTG
CCGACTATTATTTGAAAAAAGGTGCCAGCTTTGTTGCTATTAAACTTGGAAAAGAAGGCGCTTACTTTAAAACGGGGACA
AGTGAAGGATTTCTAGAAGGCTGCCGGGTCGACCGGGTGGTTGATACGGTCGGCGCCGGAGACGGATTTGCAGTCGGTGT
AATCAGCGGTATCCTAGACGGTTTGTCGTACAAGGATGCGGTGCAAAGGGGAAATGCGATTGGCGCTTTGCAAGTGCAGG
CACCGGGGGATATGGACGGTTTGCCGACCAGGGAGAAATTAGCTTCTTTTTTATCTGCTCAAAGAACGGTTCACCAAAAG
AAAGGGGATTATTAA

Upstream 100 bases:

>100_bases
GACAAAGGAGCGCCTCAAACCATTGAATTAGAGGCAAAAGTCATCATGAGAAAGTCACTTTAATCCTAGGTGCCCTCAAC
TAAGAGGAGGTTGGGAAGAG

Downstream 100 bases:

>100_bases
TATGGAGTCCAAAGTCGTTGAAAACCGTCTGAAAGAAGCAAAGCTGATTGCAGTCATTCGTTCAAAGGATAAGCAGGAGG
CCTGTCAGCAGATTGAGAGT

Product: 2-keto-3-deoxygluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGNDQLGTFILQELKKEGVDVSRV
IRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAEYPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAG
KTISFDPNVRPSLWPDQATMVHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGT
SEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDGLPTREKLASFLSAQRTVHQK
KGDY

Sequences:

>Translated_324_residues
MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGNDQLGTFILQELKKEGVDVSRV
IRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAEYPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAG
KTISFDPNVRPSLWPDQATMVHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGT
SEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDGLPTREKLASFLSAQRTVHQK
KGDY
>Mature_324_residues
MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGNDQLGTFILQELKKEGVDVSRV
IRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAEYPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAG
KTISFDPNVRPSLWPDQATMVHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGT
SEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDGLPTREKLASFLSAQRTVHQK
KGDY

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family

Homologues:

Organism=Escherichia coli, GI87081971, Length=280, Percent_Identity=28.2142857142857, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082281, Length=278, Percent_Identity=23.7410071942446, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGK_BACSU (P50845)

Other databases:

- EMBL:   L47838
- EMBL:   AL009126
- PIR:   A69648
- RefSeq:   NP_390093.1
- ProteinModelPortal:   P50845
- SMR:   P50845
- EnsemblBacteria:   EBBACT00000001976
- GeneID:   939058
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU22110
- NMPDR:   fig|224308.1.peg.2216
- GenoList:   BSU22110
- GeneTree:   EBGT00050000001879
- HOGENOM:   HBG697973
- OMA:   HDTPADI
- PhylomeDB:   P50845
- ProtClustDB:   CLSK887481
- BioCyc:   BSUB:BSU22110-MONOMER
- BRENDA:   2.7.1.45
- InterPro:   IPR011611
- InterPro:   IPR002173

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.45

Molecular weight: Translated: 35036; Mature: 35036

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGND
CCCCCEECCCHHHEEHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCH
QLGTFILQELKKEGVDVSRVIRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAE
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHH
YPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAGKTISFDPNVRPSLWPDQATM
CCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHH
VHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGT
HHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEECCC
SEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCC
LPTREKLASFLSAQRTVHQKKGDY
CCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGND
CCCCCEECCCHHHEEHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCH
QLGTFILQELKKEGVDVSRVIRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAE
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHH
YPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAGKTISFDPNVRPSLWPDQATM
CCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHH
VHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGT
HHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEECCC
SEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCC
LPTREKLASFLSAQRTVHQKKGDY
CCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377