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The map label for this gene is kamA

Identifier: 16079027

GI number: 16079027

Start: 2139454

End: 2140869

Strand: Reverse

Name: kamA

Synonym: BSU19690

Alternate gene names: 16079027

Gene position: 2140869-2139454 (Counterclockwise)

Preceding gene: 16079028

Following gene: 255767462

Centisome position: 50.78

GC content: 45.06

Gene sequence:

>1416_bases
TTGAAAAACAAATGGTATAAACCGAAACGGCATTGGAAGGAGATCGAGTTATGGAAGGACGTTCCGGAAGAGAAATGGAA
CGATTGGCTTTGGCAGCTGACACACACTGTAAGAACGTTAGATGATTTAAAGAAAGTCATTAATCTGACCGAGGATGAAG
AGGAAGGCGTCAGAATTTCTACCAAAACGATCCCCTTAAATATTACACCTTACTATGCTTCTTTAATGGACCCCGACAAT
CCGAGATGCCCGGTACGCATGCAGTCTGTGCCGCTTTCTGAAGAAATGCACAAAACAAAATACGATCTGGAAGACCCGCT
TCATGAGGATGAAGATTCACCGGTACCCGGTCTGACACACCGCTATCCCGACCGTGTGCTGTTTCTTGTCACGAATCAAT
GTTCCATGTACTGCCGCTACTGCACAAGAAGGCGCTTTTCCGGACAAATCGGAATGGGCGTCCCCAAAAAACAGCTTGAT
GCTGCAATTGCTTATATCCGGGAAACACCCGAAATCCGCGATTGTTTAATTTCAGGCGGTGATGGGCTGCTCATCAACGA
CCAAATTTTAGAATATATTTTAAAAGAGCTGCGCAGCATTCCGCATCTGGAAGTCATCAGAATCGGAACAAGAGCTCCCG
TCGTCTTTCCGCAGCGCATTACCGATCATCTGTGCGAGATATTGAAAAAATATCATCCGGTCTGGCTGAACACCCATTTT
AACACAAGCATCGAAATGACAGAAGAATCCGTTGAGGCATGTGAAAAGCTGGTGAACGCGGGAGTGCCGGTCGGAAATCA
GGCTGTCGTATTAGCAGGTATTAATGATTCGGTTCCAATTATGAAAAAGCTCATGCATGACTTGGTAAAAATCAGAGTCC
GTCCTTATTATATTTACCAATGTGATCTGTCAGAAGGAATAGGGCATTTCAGAGCTCCTGTTTCCAAAGGTTTGGAGATC
ATTGAAGGGCTGAGAGGTCATACCTCAGGCTATGCGGTTCCTACCTTTGTCGTTGACGCACCAGGCGGAGGAGGTAAAAT
CGCCCTGCAGCCAAACTATGTCCTGTCACAAAGTCCTGACAAAGTGATCTTAAGAAATTTTGAAGGTGTGATTACGTCAT
ATCCGGAACCAGAGAATTATATCCCCAATCAGGCAGACGCCTATTTTGAGTCCGTTTTCCCTGAAACCGCTGACAAAAAG
GAGCCGATCGGGCTGAGTGCCATTTTTGCTGACAAAGAAGTTTCGTTTACACCTGAAAATGTAGACAGAATCAAAAGGAG
AGAGGCATACATCGCAAATCCGGAGCATGAAACATTAAAAGATCGGCGTGAGAAAAGAGATCAGCTCAAAGAAAAGAAAT
TTTTGGCGCAGCAGAAAAAACAGAAAGAGACTGAATGCGGAGGGGATTCTTCATGA

Upstream 100 bases:

>100_bases
GGAAGGCTGATCAATAATTGCTTTATAGCCGAAGGCCTTGAAAACATGAATATTTGGTGCAAGCAACTGTAAGTCAAAAT
ATGCGCGAGGAGGAGTTCGT

Downstream 100 bases:

>100_bases
AAACATGCGAATGGTGCGGCGAGCTCGAAGCGGTGCCCGGCAGGAACACGGTGTACTGGGAGCTCCCTGATGGAACGAGG
GCTATAGAACTGACAGACAC

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKNKWYKPKRHWKEIELWKDVPEEKWNDWLWQLTHTVRTLDDLKKVINLTEDEEEGVRISTKTIPLNITPYYASLMDPDN
PRCPVRMQSVPLSEEMHKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
AAIAYIRETPEIRDCLISGGDGLLINDQILEYILKELRSIPHLEVIRIGTRAPVVFPQRITDHLCEILKKYHPVWLNTHF
NTSIEMTEESVEACEKLVNAGVPVGNQAVVLAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYVLSQSPDKVILRNFEGVITSYPEPENYIPNQADAYFESVFPETADKK
EPIGLSAIFADKEVSFTPENVDRIKRREAYIANPEHETLKDRREKRDQLKEKKFLAQQKKQKETECGGDSS

Sequences:

>Translated_471_residues
MKNKWYKPKRHWKEIELWKDVPEEKWNDWLWQLTHTVRTLDDLKKVINLTEDEEEGVRISTKTIPLNITPYYASLMDPDN
PRCPVRMQSVPLSEEMHKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
AAIAYIRETPEIRDCLISGGDGLLINDQILEYILKELRSIPHLEVIRIGTRAPVVFPQRITDHLCEILKKYHPVWLNTHF
NTSIEMTEESVEACEKLVNAGVPVGNQAVVLAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYVLSQSPDKVILRNFEGVITSYPEPENYIPNQADAYFESVFPETADKK
EPIGLSAIFADKEVSFTPENVDRIKRREAYIANPEHETLKDRREKRDQLKEKKFLAQQKKQKETECGGDSS
>Mature_471_residues
MKNKWYKPKRHWKEIELWKDVPEEKWNDWLWQLTHTVRTLDDLKKVINLTEDEEEGVRISTKTIPLNITPYYASLMDPDN
PRCPVRMQSVPLSEEMHKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
AAIAYIRETPEIRDCLISGGDGLLINDQILEYILKELRSIPHLEVIRIGTRAPVVFPQRITDHLCEILKKYHPVWLNTHF
NTSIEMTEESVEACEKLVNAGVPVGNQAVVLAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYVLSQSPDKVILRNFEGVITSYPEPENYIPNQADAYFESVFPETADKK
EPIGLSAIFADKEVSFTPENVDRIKRREAYIANPEHETLKDRREKRDQLKEKKFLAQQKKQKETECGGDSS

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=33.0246913580247, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KAMA_BACSU (O34676)

Other databases:

- EMBL:   AF015775
- EMBL:   AF006665
- EMBL:   AL009126
- PIR:   B69904
- RefSeq:   NP_389850.1
- ProteinModelPortal:   O34676
- SMR:   O34676
- EnsemblBacteria:   EBBACT00000000476
- GeneID:   940040
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19690
- NMPDR:   fig|224308.1.peg.1973
- GenoList:   BSU19690
- GeneTree:   EBGT00050000002655
- HOGENOM:   HBG687451
- OMA:   IESLIGH
- PhylomeDB:   O34676
- ProtClustDB:   CLSK873264
- BioCyc:   BSUB:BSU19690-MONOMER
- BRENDA:   5.4.3.2
- InterPro:   IPR003739
- InterPro:   IPR006638
- InterPro:   IPR022459
- PIRSF:   PIRSF004911
- SMART:   SM00729
- TIGRFAMs:   TIGR00238
- TIGRFAMs:   TIGR03820

Pfam domain/function: NA

EC number: =5.4.3.2

Molecular weight: Translated: 54074; Mature: 54074

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKWYKPKRHWKEIELWKDVPEEKWNDWLWQLTHTVRTLDDLKKVINLTEDEEEGVRIS
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
TKTIPLNITPYYASLMDPDNPRCPVRMQSVPLSEEMHKTKYDLEDPLHEDEDSPVPGLTH
EEEEEEEECHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDAAIAYIRETPEIRDCLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
DGLLINDQILEYILKELRSIPHLEVIRIGTRAPVVFPQRITDHLCEILKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIEMTEESVEACEKLVNAGVPVGNQAVVLAGINDSVPIMKKLMHDLVKIRVRPYYIYQ
CCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYVLSQSPD
ECHHHCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCC
KVILRNFEGVITSYPEPENYIPNQADAYFESVFPETADKKEPIGLSAIFADKEVSFTPEN
HHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHH
VDRIKRREAYIANPEHETLKDRREKRDQLKEKKFLAQQKKQKETECGGDSS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNKWYKPKRHWKEIELWKDVPEEKWNDWLWQLTHTVRTLDDLKKVINLTEDEEEGVRIS
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
TKTIPLNITPYYASLMDPDNPRCPVRMQSVPLSEEMHKTKYDLEDPLHEDEDSPVPGLTH
EEEEEEEECHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDAAIAYIRETPEIRDCLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
DGLLINDQILEYILKELRSIPHLEVIRIGTRAPVVFPQRITDHLCEILKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIEMTEESVEACEKLVNAGVPVGNQAVVLAGINDSVPIMKKLMHDLVKIRVRPYYIYQ
CCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYVLSQSPD
ECHHHCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCC
KVILRNFEGVITSYPEPENYIPNQADAYFESVFPETADKKEPIGLSAIFADKEVSFTPEN
HHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHH
VDRIKRREAYIANPEHETLKDRREKRDQLKEKKFLAQQKKQKETECGGDSS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377; 10839984