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The map label for this gene is deoD

Identifier: 16079021

GI number: 16079021

Start: 2135470

End: 2136171

Strand: Reverse

Name: deoD

Synonym: BSU19630

Alternate gene names: 16079021

Gene position: 2136171-2135470 (Counterclockwise)

Preceding gene: 255767460

Following gene: 16079020

Centisome position: 50.67

GC content: 41.31

Gene sequence:

>702_bases
ATGAGTGTACATATAGGTGCTGAAAAAGGACAAATTGCGGATACTGTGCTTTTGCCGGGAGATCCTCTCAGAGCAAAATT
TATTGCAGAAACGTATCTTGAAAATGTAGAATGCTACAATGAAGTCAGAGGCATGTATGGATTTACGGGTACATATAAAG
GTAAAAAAATCTCAGTACAAGGCACGGGAATGGGAGTTCCGTCTATTTCAATTTATGTGAATGAATTAATTCAAAGCTAC
GATGTGCAAAATCTAATAAGAGTCGGTTCCTGCGGCGCTATTCGTAAAGATGTCAAAGTGCGAGACGTCATTTTGGCGAT
GACCTCCTCAACTGATTCACAAATGAACAGAGTTGCTTTCGGAAGCGTTGATTTTGCGCCTTGCGCAGATTTCGAGCTTT
TAAAAAATGCCTATGATGCCGCAAAGGATAAAGGTGTGCCGGTGACTGTAGGAAGCGTATTTACAGCTGACCAGTTCTAC
AATGACGATTCGCAAATTGAAAAACTTGCAAAATACGGTGTGCTTGGCGTTGAAATGGAAACAACTGCATTGTATACATT
AGCAGCGAAGCACGGAAGAAAAGCCCTGTCAATTCTCACCGTGAGTGATCACGTATTAACAGGAGAAGAAACGACAGCGG
AAGAGCGTCAAACGACATTTCATGATATGATAGAAGTGGCTTTACATTCCGTATCACAATAA

Upstream 100 bases:

>100_bases
ATATATTCCTTTATAATCAATGCTGAAGTTTGTTTCATCATGACATTCGTTGTAAAATGGACGGGCTGGATGATAATTTA
GATTTACAGGAGGATATGAG

Downstream 100 bases:

>100_bases
AATATATCAAGAGGCGTGCTGGGTGCCGGCAGCCTCTTCTTTATGCATGCGGAAACGATTGATAAAAGGAAGGTAATGTA
ATATGAAAAAGTCCGGTAAA

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP; Purine nucleoside phosphorylase II; PU-NPase II

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYKGKKISVQGTGMGVPSISIYVNELIQSY
DVQNLIRVGSCGAIRKDVKVRDVILAMTSSTDSQMNRVAFGSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFY
NDDSQIEKLAKYGVLGVEMETTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQTTFHDMIEVALHSVSQ

Sequences:

>Translated_233_residues
MSVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYKGKKISVQGTGMGVPSISIYVNELIQSY
DVQNLIRVGSCGAIRKDVKVRDVILAMTSSTDSQMNRVAFGSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFY
NDDSQIEKLAKYGVLGVEMETTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQTTFHDMIEVALHSVSQ
>Mature_232_residues
SVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYKGKKISVQGTGMGVPSISIYVNELIQSYD
VQNLIRVGSCGAIRKDVKVRDVILAMTSSTDSQMNRVAFGSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFYN
DDSQIEKLAKYGVLGVEMETTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQTTFHDMIEVALHSVSQ

Specific function: Cleavage of adenosine and its derivatives

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=58.5152838427948, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1790265, Length=209, Percent_Identity=31.1004784688995, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_BACSU (O34925)

Other databases:

- EMBL:   AF015775
- EMBL:   AF006665
- EMBL:   AL009126
- PIR:   D69614
- RefSeq:   NP_389844.1
- ProteinModelPortal:   O34925
- SMR:   O34925
- EnsemblBacteria:   EBBACT00000002197
- GeneID:   940038
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19630
- NMPDR:   fig|224308.1.peg.1967
- GenoList:   BSU19630
- GeneTree:   EBGT00050000000479
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- PhylomeDB:   O34925
- ProtClustDB:   PRK05819
- BioCyc:   BSUB:BSU19630-MONOMER
- BRENDA:   2.4.2.1
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25378; Mature: 25247

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYKGKKISVQ
CEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEE
GTGMGVPSISIYVNELIQSYDVQNLIRVGSCGAIRKDVKVRDVILAMTSSTDSQMNRVAF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCHHHHCCHHHHEEEEEECCCCHHHHHEEE
GSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFYNDDSQIEKLAKYGVLGVEME
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCEEEHHHHCCCHHHHHHHHHHCEEEEEEH
TTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQTTFHDMIEVALHSVSQ
HHHHHHHHHHCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVHIGAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYKGKKISVQ
EEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEE
GTGMGVPSISIYVNELIQSYDVQNLIRVGSCGAIRKDVKVRDVILAMTSSTDSQMNRVAF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCHHHHCCHHHHEEEEEECCCCHHHHHEEE
GSVDFAPCADFELLKNAYDAAKDKGVPVTVGSVFTADQFYNDDSQIEKLAKYGVLGVEME
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCEEEHHHHCCCHHHHHHHHHHCEEEEEEH
TTALYTLAAKHGRKALSILTVSDHVLTGEETTAEERQTTFHDMIEVALHSVSQ
HHHHHHHHHHCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377