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The map label for this gene is desR

Identifier: 16078980

GI number: 16078980

Start: 2091705

End: 2092304

Strand: Direct

Name: desR

Synonym: BSU19200

Alternate gene names: 16078980

Gene position: 2091705-2092304 (Clockwise)

Preceding gene: 16078979

Following gene: 255767451

Centisome position: 49.62

GC content: 43.0

Gene sequence:

>600_bases
ATGATTAGTATATTTATTGCAGAAGATCAGCAAATGCTGCTGGGCGCTTTAGGATCACTTCTAAACCTCGAAGACGATAT
GGAAGTCGTAGGCAAAGGTACAACCGGCCAAGATGCTGTTGATTTTGTCAAAAAACGCCAGCCTGATGTATGTATTATGG
ACATTGAAATGCCCGGAAAAACAGGGCTTGAAGCTGCTGAGGAGCTAAAAGATACAGGCTGCAAAATTATCATCTTAACC
ACCTTCGCCAGACCCGGTTACTTTCAGAGAGCTATTAAAGCTGGCGTTAAAGGCTATTTGTTAAAAGACAGTCCGAGTGA
AGAGCTGGCCAACGCCATCCGTAGCGTCATGAACGGAAAACGCATCTATGCACCTGAACTGATGGAGGACTTATACAGCG
AAGCTAACCCTCTTACAGATAGAGAAAAAGAAGTGCTCGAACTTGTGGCTGACGGTAAAAACACAAAAGAAATCGCTCAG
GAACTCAGCATCAAAAGCGGGACGGTGCGGAATTATATCTCAATGATTCTAGAAAAGCTTGAAGTGAAAAATCGAATTGA
AGCCATTACCCGGTCAAAAGAAAAAGGCTGGTTTAAATAA

Upstream 100 bases:

>100_bases
TGAGTTTGCAAACGGAAGCCTTCACATCGATACCGAAAACGGGACCAAGCTTACCATGGCAATTCCTAATAATTCAAAAT
AAACATAAAGGATGGCTTAT

Downstream 100 bases:

>100_bases
AAAAGGATCTTGGCATCTGCCAGGATCCTTTTTGTTAACCTGAAATTCCCGTTTGAGAACCTCGTCGCAACCAGAATTAA
ATTGATCCATATCCTCGCTC

Product: two-component response regulator DesK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILT
TFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGKRIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQ
ELSIKSGTVRNYISMILEKLEVKNRIEAITRSKEKGWFK

Sequences:

>Translated_199_residues
MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILT
TFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGKRIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQ
ELSIKSGTVRNYISMILEKLEVKNRIEAITRSKEKGWFK
>Mature_199_residues
MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILT
TFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGKRIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQ
ELSIKSGTVRNYISMILEKLEVKNRIEAITRSKEKGWFK

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1790102, Length=198, Percent_Identity=34.3434343434343, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788222, Length=199, Percent_Identity=28.643216080402, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=33.6734693877551, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788712, Length=194, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787473, Length=199, Percent_Identity=29.6482412060301, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=24.8756218905473, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DESR_BACSU (O34723)

Other databases:

- EMBL:   AF027868
- EMBL:   AL009126
- PIR:   D69901
- RefSeq:   NP_389801.1
- HSSP:   P11470
- ProteinModelPortal:   O34723
- SMR:   O34723
- DIP:   DIP-48967N
- EnsemblBacteria:   EBBACT00000001341
- GeneID:   939664
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19200
- NMPDR:   fig|224308.1.peg.1924
- GenoList:   BSU19200
- GeneTree:   EBGT00070000032004
- HOGENOM:   HBG753323
- OMA:   RRVYAPE
- PhylomeDB:   O34723
- ProtClustDB:   CLSK887414
- BioCyc:   BSUB:BSU19200-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.25.40.10
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421
- SMART:   SM00448

Pfam domain/function: PF00196 GerE; PF00072 Response_reg; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 22177; Mature: 22177

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGK
CEEEEEECCHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCC
TGLEAAEELKDTGCKIIILTTFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGK
CCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCC
RIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQELSIKSGTVRNYISMILEKL
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
EVKNRIEAITRSKEKGWFK
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGK
CEEEEEECCHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCC
TGLEAAEELKDTGCKIIILTTFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGK
CCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCC
RIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQELSIKSGTVRNYISMILEKL
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
EVKNRIEAITRSKEKGWFK
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377