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The map label for this gene is czrA

Identifier: 16078972

GI number: 16078972

Start: 2084786

End: 2085109

Strand: Reverse

Name: czrA

Synonym: BSU19120

Alternate gene names: 16078972

Gene position: 2085109-2084786 (Counterclockwise)

Preceding gene: 16078974

Following gene: 16078970

Centisome position: 49.46

GC content: 42.59

Gene sequence:

>324_bases
ATGACTGAATTTAGAGAAACGGAACAATCGGCTGCTGATCTGGACGAGGAGACGCTGTTTCTAGTCGCGCAAACATTCAA
AGCGCTTTCAGATCCTACCCGAATCAGAATTCTCCATTTATTGTCCCAAGGTGAGCATGCAGTAAACGGAATTGCAGAAA
AGCTGAATTTACTGCAATCCACTGTGTCCCACCAGCTTAGATTTTTAAAAAATCTCCGGCTTGTCAAATCGCGCAGAGAA
GGAACATCGATTTATTACTCTCCGGAGGATGAACATGTTTTAGATGTTCTTCAGCAAATGATCCATCATACACAGCATGA
TTGA

Upstream 100 bases:

>100_bases
AAATTTAAACTATGAGATTGAAATGGAATACAAGCAGGCTGGTTTGCACTCAAGCGCATTTGTTATAAGATAAAACTATG
AATAAAGAAAGGTGATACAT

Downstream 100 bases:

>100_bases
AAAAGACATCCTTGCTTAACTCGCTGTTAGCGGGCAAGGATGTCTTTTTCTTTATTGTATTCGTGCTGTTCAAGTTCGTT
TCTGCTGAGCTTGATGATAA

Product: ArsR-SmtB repressors family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MTEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQGEHAVNGIAEKLNLLQSTVSHQLRFLKNLRLVKSRRE
GTSIYYSPEDEHVLDVLQQMIHHTQHD

Sequences:

>Translated_107_residues
MTEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQGEHAVNGIAEKLNLLQSTVSHQLRFLKNLRLVKSRRE
GTSIYYSPEDEHVLDVLQQMIHHTQHD
>Mature_106_residues
TEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQGEHAVNGIAEKLNLLQSTVSHQLRFLKNLRLVKSRREG
TSIYYSPEDEHVLDVLQQMIHHTQHD

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CZRA_BACSU (O31844)

Other databases:

- EMBL:   AL009126
- PIR:   E69930
- RefSeq:   NP_389793.1
- HSSP:   P30340
- ProteinModelPortal:   O31844
- SMR:   O31844
- EnsemblBacteria:   EBBACT00000002332
- GeneID:   939658
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19120
- NMPDR:   fig|224308.1.peg.1916
- GenoList:   BSU19120
- GeneTree:   EBGT00050000000705
- HOGENOM:   HBG742701
- OMA:   QSTVSHQ
- ProtClustDB:   CLSK887408
- BioCyc:   BSUB:BSU19120-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001845
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00778
- SMART:   SM00418

Pfam domain/function: PF01022 HTH_5

EC number: NA

Molecular weight: Translated: 12379; Mature: 12248

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00846 HTH_ARSR_1; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQGEHAVNGIAEKLNLLQS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TVSHQLRFLKNLRLVKSRREGTSIYYSPEDEHVLDVLQQMIHHTQHD
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQGEHAVNGIAEKLNLLQS
CCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TVSHQLRFLKNLRLVKSRREGTSIYYSPEDEHVLDVLQQMIHHTQHD
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377