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The map label for this gene is ppsB

Identifier: 16078894

GI number: 16078894

Start: 1982565

End: 1990247

Strand: Reverse

Name: ppsB

Synonym: BSU18330

Alternate gene names: 16078894

Gene position: 1990247-1982565 (Counterclockwise)

Preceding gene: 255767429

Following gene: 16078893

Centisome position: 47.21

GC content: 45.16

Gene sequence:

>7683_bases
ATGGCACAATCGGCACAAATTCAAGATATTTATCCGTTATCGCACATGCAGGAAGGAATGCTGTTTCATTCACTAATGGA
TTTCAGCTCGAAAGCATATATCGAACAGACCTCGTTTACGATCACAGGGAATCTATGCGTCGACTCGTTTCAAAAGAGCT
TAAACCTTCTTGTTTCTAGATATGATATTTTCAGAACGATTTTCATTAAAGAAGTACCAGATCTTACAGGTCCGCAGCAG
GTAGTTCTATCAAACCGTGAATTGACAGTATATAGAGAAGATATTTCTCGCCTGGCTGATCAAGAACAGCAGACGCTGAT
TGATGCTTTTATGACTAAGGATCGGGAAAAAGGATTTGATTTGCAAAAAGATCCTTTAATGCGTCTTGCCCTTTTTGATA
GAGGAGACAGCCAATATACATGTGTCTGGACACATCACCATATCATCATGGATGGGTGGTGTCTCGGCATTATTCTTAAA
GAGTTTTTCAGCATGTATGATTCGCTCAAAAATAACTCACCTGTACAGCTTGGCAGCACGGTGCCGTACAGCCGTTATAT
TGAATGGCTCGGAGAACAAGATCAAGAAGAGACTGCTGCCTACTGGAGCGAATATTTGAAGGAGTACGGCAATACTGCTT
CTATTCCCCGAATAAAGCGCCGCACGGCAGACGGGAATTATAAAGCCGACCAGGTCAGCTTTTCATTAGCGCCGGATATG
GTTGAGAAACTGACAGAGGCTGCCCAAAACTGGGGAGTGACATTAAACACGCTGTTTATGAGTATTTGGGGCGTGCTGCT
CCATCGATATAATGCTGCAGATGATGCCGTTTTTGGCTCCGTCATTTCGGGACGCCCGTCAGCGATTGACGGGATTGAAT
CAATGGTCGGTTTGTTTATCAATACTGTTCCAGTGCGAATCCGATCTGCGGAAGGCATAACATTTTCTTCGCTGGTCAAA
GCCGTGCAGGAGGATATTTTATCATCTGAACAGCATGGGTATTATCCGCTTTATGAGATTCAAAACCATAGTCCATTGAA
GCAAGGGTTGATCGATCATATTTTTGTTTTTGAAAATTACCCTGTACAGCTTCATCAGGCATTAAGCGTGGAGAGTGAAA
ATGACGAAGGCGCTCTGAAGCTGAGTGACATTTCAATGTCGGAACAAACCAATTACGACTTTAATATCGTTATCGTTCCG
GGAGAATCATTTTATATCAAATTCAGCTACAACGCAGACGTTTACGAGCGGGAGGAGATGCTGAGGATTCAGGGGCATCT
AAAGCAAGCACTGGATTGCATTTTGACAAATCCCGATGTTGCCGTCAGTGACATCAATATCGTGCCGCCGGAGGAGCAAC
AGGTTATCCAATTGTTTAACGAAACTGAGCGTCCTTATGTGAACAAAACGATACCCCAATTGTTTGAGGAACAAGCTCAC
AAAACACCTGAAGCTGCTGCATTGAAAATGGGAAACGAGTGCTGGACCTATCGCCAGTTACAAGTAAGAGCCAATCAGAT
TGCGCACGCCCTGATAGAAAAAGGCGTTGGATCTGGGGATATCGTTGCTGTAATGATGGGCCGGTCAATGGAAATGCCTG
CAGCTCTGCTTGGGATTTGGAAAGCAGGCGGCGCTTATATGCCGCTTGATCCACATTTTCCAGCAGAACGTCTTTCTTTT
CTTCTGAAGGACAGTCAAGCGGCTCAATTGCTGATAGAAGAAGACCTTATTTCCTTGATCCCTCCGTCCTATGAAGGAAA
TACGATAACGATAGAACATACAGAAAGTTACCAAACAGAAGCGCCAAATATGCCGCCAGGTGATCTAGCCTACTTGATCT
ATACGTCGGGAACGACGGGGCGCCCTAAAGGGGTTTTAGTTGATCATCACGGTATTGCCAATACATTGCAATGGAGACGG
GAAGAGTATAGCATGACCGAACAGGATATATCCCTCCATTTGTTTTCGTACGTGTTTGACGGCTGTGTAACGAGCTTATT
TACCCCGCTTTTATCTGGTGCGTGCGTACTGCTGACAACAGATGACGAAGCGAAGGATGTGCTGGCCCTTAAGCGAAAAA
TAGCCCGTTATAAGGTCAGCCACATGATCATTGTTCCTTCCCTGTACAGGGTGTTATTGGAAGTGATGACTGCTGACGAT
GCAAAAAGTCTTCGTATTGTGACATTTGCGGGTGAAGCGGTCACGCCTGATCTGCTTGAGTTGAATCAAATAATTTGTCC
TTCTGCTGAACTGGCAAATGAATACGGGCCCACAGAAAACAGTGTGGCAACAACAATATTGCGGCATCTGAATAAAAAAG
AGAGGATCACGATCGGACACCCGATCAGAAACACAAAAGTATTTGTTTTGCACGGAAATCAAATGCAGCCGATCGGCGCG
GCGGGTGAACTGTGTATTTCCGGCGCGGGTCTTGCGAGAGGATACTACAAACAGCAAGAGCTGACACAGAAAGCATTCTC
CGATCATCCATTCCTTGAAGGGGAGCGTTTATACCGAACAGGTGATGCAGGCCGCTTTTTGCCTGATGGAACGATTGAAT
ATATTGGACGTTTTGATGATCAAGTGAAAATTAGGGGTTATCGTATTGAACTGAGAGAGATTGAAACAGTTCTTCGACAA
GCACCGGGGGTAAAAGAAGCAGCGGTACTGGCCCGTGATGTTTCTGCTGAGGAAAAGGAGCTCGTTGCTTATATCGTTCC
GGAAAAGGGAAACAGCCTCCCAGATTTGTATCAGCATCTTGCCGGGACATTGCCGTCCTATATGATCCCAGCAAGTATTA
TCAACATCAGCCAGATGCCATTAACATCCAGCGGCAAGCTTGACAGGTTTGCGCTTCCTGAACCAGAAAACAATACGAGT
GTCACATATATGGCGCCCCGAACCTTAATCGAAGCTGATCTCGCACATATTTGGGAAGATGTGCTGAATAAACAGCACAT
CGGCATTCGTGATGATTTCTTTCAGTTAGGCGGACAGTCCTTAAAAGCGGCCGCACTGGTATCAAGAATACATAAAAAGC
TTAATGTCGAGCTGCCGCTCAGTGAGGTGTTTTCTTATCCGACGGTTGAAAGCATGGCGGTCAAATTGATGAGCTTAAAA
GAACACGCTTTTACACAGATTGAACCTGCGGATCAAAGAGATGTCTATCCGCTGTCTTTCTCGCAAAAACGATTATATGC
TCTTCATCAGCTGGCAGATGACAGCACAGGCTACAACATGCCAGCTGTACTTGAATTACGCGGAAATCTGAATCGCCAGC
GGTTGAGAAGCGTTCTCACAGAACTTGTGAATCGGCATGAAGCATTACGGACTGTTTTTGTGCTTGACAGAGACGAGCCT
GTGCAGATCATTTATCCAGAGATGGCTTTTGATCTAAAAGAGCTTGAAATGGAATCAGAACAAATGCTTGAGTCTGCAAT
CGAGACCTTTATCAAACCGTTTTATCTATCATCCGGTCCGCTTTTTAGAGCATGTGTCATTACAATGGGCAATAATCGCG
GCTTTTTGCTGCTCGATATGCACCATATTATTGCCGACGGTGTCTCGATGAGCACTCTTGTCCAAGAATTTACTGACTTA
TATTGCGGAAAAGAGTTGCCAGCTTTAAACCTGCATTATAAGGATTTTGCTGTTTGGCAGCAAGAGAAGCACCCGAAAGA
GCTATACAAAAAACAGGAGGCCTACTGGCTCGGTCAGCTTGGCGGGAGTCTTCCTACACTAGAATTACCGCTTGATAAAA
CAAGGCCGCGTCTCCCTGATTTCAGGGGTGGAACAATTGAAGTCAACATTGATAAAGACATGGCTGATGAACTGCACCGT
TTAATGGCTGAAACGGGAACAACATTGTATATGATTCTTCTGGCTGTCTATTCTATTTTGTTATCTAAGCTAAGCGGGCA
AGAGGATATTGTTGTCGGTTCGCCTGCTGCCGGAAGACCGCACGCTGATCTGGAGCGCGTCATCGGAATGTTCGTCAATA
CATTGGCGATGCGCAGCAAGCCCGAGGGCCACAAAACGTTCAGCTCCTATTTGCATGACATTCGCCACCTGGCTCTGACC
GCTTACGAGCATCAGGATTATCCTTTTGAGGAGCTGGCAGATAAGCTCGATACAAATCGAGAGGTAAATCGCAACCCGCT
GTTCGATGCGATGCTTGTGCTTCAAAGCAGTGAAGATTTCCGGTTCGAAGTGCCTGGTCTGTCGATTTCGTCTGTCACTC
CTAAACATGATATATCTAAATTCGATTTAACATTACATGCTGAGGAGCATCTGAGTGGAATACGCTGCCGTTTTGAATAC
AGCACTGCTCTTTTTGAAGAAGAAACCATTACGCAGTGGGCATCCTATTTTATTGAATTGGTAAAAGGGGTAACGGCGGA
TACTGAGATGAGAATTTCGAACATGCAATTGCTTCCTGCTGCAGAGCGTAGGTTACTCCTTGAAAAAATGGGGCAGTATG
CAGCTTATCCGAGAAATGAAAACATAGTAAGCTTATTTGAAAAGCAAGTAGCTCAGTATCCGGAGCATATCGCAGTGGTG
TGCGGCCATTCTCAGCTTACGTATCGAGACCTGAATGAAAAAGCCGAGCGGGCAGCTGCTATGCTGATCAAACAAGGGGT
CAGAACTGGCGATATCGTCGGTCTGATGCTCGATCGGTCACCTGATATGATCATTGGCGTTTTATCGATTTTAAAAGCTG
GCGGGGCCTATTTGCCGATTGATCCTGAATATCCCAAGGAGCGTATTAGCTTTATGCTCAATGACAGCGGAGCAAAACTG
CTGCTGACAGAGCGCGGTCTAAACAAACCTGCAGACTACACCGGGCATATTTTGTATATCGATGAATGTGAAAACAACTC
AATTCCGGCTGATGTAAACATTGAAGAAATAGTAACGGATCAGCCCGCATACGTGATATACACATCTGGAACGACTGGTC
AGCCAAAGGGAGTCATTGTCGAGCACCGCAATGTGATCAGTCTCTTGAAGCATCAAAACCTGCCTTTTGAATTTAACCAT
GAAGACGTCTGGACGTTATTTCATTCTTATTGCTTTGATTTCTCTGTATGGGAGATGTTCGGTGCGTTATTGAACGGAAG
TACATTAGTCGTGGTCTCTAAAGAAACAGCCCGTGACCCCCAAGCATTCCGATTATTGTTAAAAAAAGAGCGCGTCACTG
TACTCAATCAGACCCCGACTGCTTTTTACGGCTTGATGCTTGAAGACCAAAATCATACAGATCATTTAAACATCCGCTAT
GTGATTTTTGGCGGCGAAGCCTTACAGCCCGGATTGCTTCAAAGCTGGAATGAAAAATATCCTCATACTGATTTGATTAA
TATGTACGGTATTACAGAAACAACGGTCCATGTAACATTCAAAAAATTGTCCGCAGCAGACATTGCAAAAAATAAAAGCA
ATATCGGCCGGCCTCTTTCTACTCTGCAGGCTCATGTGATGGATGCCCATATGAACCTGCAGCCGACCGGAGTTCCAGGG
GAGCTGTATATAGGCGGCGAAGGTGTGGCACGGGGATATCTCAACAGAGATGAGCTGACCGCTGACCGTTTTGTATCCAA
TCCTTATCTTCCGGGAGACAGATTATACCGAACAGGAGATCTTGCTAAGCGCCTGTCAAATGGCGAGCTGGAATACTTAG
GCCGCATTGATGAGCAGGTGAAAGTCAGAGGGCACCGTATTGAGTTAGGCGAAATCCAAGCGGCACTTCTTCAGTATCCA
ATGATTAAAGAGGCGGCTGTCATTACCAGAGCAGACGAGCAAGGGCAAACAGCTATATATGCATATATGGTGATAAAAGA
TCAACAGGCTGCGAATATATCAGACATCCGAACTTACCTAAAAAACGCCTTGCCTGACTTTATGCTGCCTGCCCGTATGA
TACAAATTGACAGCATCCCGGTGACTGTTAATGGAAAGCTCGATCAGAAAGCCCTGCCAGAGCCTGAAAAACAAGCTTAT
ACAGCTGATGATATCAGTCCTAGAAATGAGATTGAAACGGTGATGGCTGAAATTTGGGAAGAGCTTCTTAATGTAGATGA
GCTGGGTGTAAGCGCCAATTTCTTTAAGCTTGGCGGAGACTCTATTAAAGCGCTGCAGGTTTGTGCCAGACTGAAGCAGC
GCGGATTTGAAACGACAGTACGTGAGATGTTTGAACATCAGACTCTTGGTGAACTGTCCGCCCGGGTTCGAAAAGACGTA
CGCGCCATTGACCAAGGCCCGGTCGAAGGCGAGATTACTTGGACACCTATCCAGCAGTGGTTTTTCTCGCAATCTCTGGA
AAGCCATCATTTTAACCAATCCGTTATGATCTACCGGGCTGAACGATTTGATGAGGCTGCGCTTAGAAAAGTACTAAAAA
GCCTTGTGACTCATCATGATGCACTGAGAATCGTATGCCGGCATGAAGATGGCAGGCAAGTGCAGATAAACAGAGGGATA
GATCTTTCAGATGAGGAGCTATATGCACTTGAACTGTTTGATGTAAAGGATAGCCTAACAGAAGCCCGGAACACGATTGA
GGAAGCAGCCAGCCGGATGCAAGAACATATTCGTTTGGAAACCGGCCCCTTACTTCACGCTGGATTGTTTAGAACCGAGA
ATGGTGACCATTTATTTCTAACGATTCATCACTTAGTTGTTGATGCGGTTTCTTGGCGCATTTTGTTTGAGGATTTTTCA
ACAGCTTACAAACAGGCAGTCTCAGGAGAATCTATTAAACTGCCGCAAAAAACAGATTCATATTTAACGTATTCACAAAG
AATAGCTGACTACTCTATAAGCCGCCAGGTGCAGCGCGAAGCAGCGTACTGGGATGAGTGCGAGAACCGTCACATCCAGC
CTATTCCAAAAGACAATGACGCAGCATCTAACACATTCAAAGATACAGAAGTGATTGATTTTGAGCTATCTCGCCATCAC
ACAGAATTACTATTAACGGCTGCACATAAAGCTTACAGCACGGAGATGAATGATATCCTTCTGACAGCTTTAGGTCTTGC
TTTGCAGAAATGGACGGGAAATAACCAATTTAAAATCAGCATGGAGGGCCATGGAAGGGAATCATATCTTGAGGACATCG
ATATTAGCAGAACTGTTGGCTGGTTCACCTCCATTTATCCTGTGTGGCTTGATATGAGAGATTCCGATCATAAGGACAAA
GAAGAGCGGCTGGGCCACCTTATTAAACAGACAAAAGATATGCTGCACCGTATACCGCATAAAGGCGCGGGCTACGGCGT
GCTGAAATATATCAGCAAAAGATGGGGCTCTCAGAAAAACAGCCCAGAAATCAGCTTTAATTATTTAGGCCAGTTTGATC
AGGATATTCAATCAAATGCCTTTGAGGTGTCTGACATCAAGCCAGGAAATGAGATCAGCCCGAACTGGGAGCGTCCTTAT
GCACTGGATATCAGCGGCGCCGTTTCTTCGGGGTGCCTGAACATGCACATCATCTATAACAGGTTTCAATTTGAGGAAAA
AACAATCCAAACATTTTCCAGGCATTTTAAACAGACTCTGGAAAACATCATTGAGCATTGTACCGGCAAAGAAAACCAAG
AGTGGAGCGCATCTGATTTCACTGATGAAGACTTAACGCTTGATGAATTGAGTGAGATCATGGGAGCCGTCAACAAACTA
TAG

Upstream 100 bases:

>100_bases
ATTGAGCGATTTCAGCAATAAAGAATTAACGTTGTCTGCATTATCTAGCATCGAAGATCTCGTGAAAGATCTTTAACTTT
TGAAAAGGTGTGTGGAATTG

Downstream 100 bases:

>100_bases
GAGAGGAGATTCACTGATGCCGCAGCAACCTGAAATACAGGATATATACCCTTTGTCATTTATGCAGGAAGGGATGCTTT
TTCACTCACTGTATGATGAA

Product: plipastatin synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Peptide synthase 2; ATP-dependent tyrosine adenylase 1; TyrA 1; Tyrosine activase 1; ATP-dependent threonine adenylase; ThrA; Threonine activase

Number of amino acids: Translated: 2560; Mature: 2559

Protein sequence:

>2560_residues
MAQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNLCVDSFQKSLNLLVSRYDIFRTIFIKEVPDLTGPQQ
VVLSNRELTVYREDISRLADQEQQTLIDAFMTKDREKGFDLQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILK
EFFSMYDSLKNNSPVQLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRTADGNYKADQVSFSLAPDM
VEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSVISGRPSAIDGIESMVGLFINTVPVRIRSAEGITFSSLVK
AVQEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYPVQLHQALSVESENDEGALKLSDISMSEQTNYDFNIVIVP
GESFYIKFSYNADVYEREEMLRIQGHLKQALDCILTNPDVAVSDINIVPPEEQQVIQLFNETERPYVNKTIPQLFEEQAH
KTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSGDIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAERLSF
LLKDSQAAQLLIEEDLISLIPPSYEGNTITIEHTESYQTEAPNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANTLQWRR
EEYSMTEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADD
AKSLRIVTFAGEAVTPDLLELNQIICPSAELANEYGPTENSVATTILRHLNKKERITIGHPIRNTKVFVLHGNQMQPIGA
AGELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQ
APGVKEAAVLARDVSAEEKELVAYIVPEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTS
VTYMAPRTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPLSEVFSYPTVESMAVKLMSLK
EHAFTQIEPADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLNRQRLRSVLTELVNRHEALRTVFVLDRDEP
VQIIYPEMAFDLKELEMESEQMLESAIETFIKPFYLSSGPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDL
YCGKELPALNLHYKDFAVWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFRGGTIEVNIDKDMADELHR
LMAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSKPEGHKTFSSYLHDIRHLALT
AYEHQDYPFEELADKLDTNREVNRNPLFDAMLVLQSSEDFRFEVPGLSISSVTPKHDISKFDLTLHAEEHLSGIRCRFEY
STALFEEETITQWASYFIELVKGVTADTEMRISNMQLLPAAERRLLLEKMGQYAAYPRNENIVSLFEKQVAQYPEHIAVV
CGHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRSPDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKL
LLTERGLNKPADYTGHILYIDECENNSIPADVNIEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNH
EDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLLLKKERVTVLNQTPTAFYGLMLEDQNHTDHLNIRY
VIFGGEALQPGLLQSWNEKYPHTDLINMYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPG
ELYIGGEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYP
MIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKLDQKALPEPEKQAY
TADDISPRNEIETVMAEIWEELLNVDELGVSANFFKLGGDSIKALQVCARLKQRGFETTVREMFEHQTLGELSARVRKDV
RAIDQGPVEGEITWTPIQQWFFSQSLESHHFNQSVMIYRAERFDEAALRKVLKSLVTHHDALRIVCRHEDGRQVQINRGI
DLSDEELYALELFDVKDSLTEARNTIEEAASRMQEHIRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFS
TAYKQAVSGESIKLPQKTDSYLTYSQRIADYSISRQVQREAAYWDECENRHIQPIPKDNDAASNTFKDTEVIDFELSRHH
TELLLTAAHKAYSTEMNDILLTALGLALQKWTGNNQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDK
EERLGHLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNAFEVSDIKPGNEISPNWERPY
ALDISGAVSSGCLNMHIIYNRFQFEEKTIQTFSRHFKQTLENIIEHCTGKENQEWSASDFTDEDLTLDELSEIMGAVNKL

Sequences:

>Translated_2560_residues
MAQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNLCVDSFQKSLNLLVSRYDIFRTIFIKEVPDLTGPQQ
VVLSNRELTVYREDISRLADQEQQTLIDAFMTKDREKGFDLQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILK
EFFSMYDSLKNNSPVQLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRTADGNYKADQVSFSLAPDM
VEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSVISGRPSAIDGIESMVGLFINTVPVRIRSAEGITFSSLVK
AVQEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYPVQLHQALSVESENDEGALKLSDISMSEQTNYDFNIVIVP
GESFYIKFSYNADVYEREEMLRIQGHLKQALDCILTNPDVAVSDINIVPPEEQQVIQLFNETERPYVNKTIPQLFEEQAH
KTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSGDIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAERLSF
LLKDSQAAQLLIEEDLISLIPPSYEGNTITIEHTESYQTEAPNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANTLQWRR
EEYSMTEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADD
AKSLRIVTFAGEAVTPDLLELNQIICPSAELANEYGPTENSVATTILRHLNKKERITIGHPIRNTKVFVLHGNQMQPIGA
AGELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQ
APGVKEAAVLARDVSAEEKELVAYIVPEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTS
VTYMAPRTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPLSEVFSYPTVESMAVKLMSLK
EHAFTQIEPADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLNRQRLRSVLTELVNRHEALRTVFVLDRDEP
VQIIYPEMAFDLKELEMESEQMLESAIETFIKPFYLSSGPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDL
YCGKELPALNLHYKDFAVWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFRGGTIEVNIDKDMADELHR
LMAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSKPEGHKTFSSYLHDIRHLALT
AYEHQDYPFEELADKLDTNREVNRNPLFDAMLVLQSSEDFRFEVPGLSISSVTPKHDISKFDLTLHAEEHLSGIRCRFEY
STALFEEETITQWASYFIELVKGVTADTEMRISNMQLLPAAERRLLLEKMGQYAAYPRNENIVSLFEKQVAQYPEHIAVV
CGHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRSPDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKL
LLTERGLNKPADYTGHILYIDECENNSIPADVNIEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNH
EDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLLLKKERVTVLNQTPTAFYGLMLEDQNHTDHLNIRY
VIFGGEALQPGLLQSWNEKYPHTDLINMYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPG
ELYIGGEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYP
MIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKLDQKALPEPEKQAY
TADDISPRNEIETVMAEIWEELLNVDELGVSANFFKLGGDSIKALQVCARLKQRGFETTVREMFEHQTLGELSARVRKDV
RAIDQGPVEGEITWTPIQQWFFSQSLESHHFNQSVMIYRAERFDEAALRKVLKSLVTHHDALRIVCRHEDGRQVQINRGI
DLSDEELYALELFDVKDSLTEARNTIEEAASRMQEHIRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFS
TAYKQAVSGESIKLPQKTDSYLTYSQRIADYSISRQVQREAAYWDECENRHIQPIPKDNDAASNTFKDTEVIDFELSRHH
TELLLTAAHKAYSTEMNDILLTALGLALQKWTGNNQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDK
EERLGHLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNAFEVSDIKPGNEISPNWERPY
ALDISGAVSSGCLNMHIIYNRFQFEEKTIQTFSRHFKQTLENIIEHCTGKENQEWSASDFTDEDLTLDELSEIMGAVNKL
>Mature_2559_residues
AQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNLCVDSFQKSLNLLVSRYDIFRTIFIKEVPDLTGPQQV
VLSNRELTVYREDISRLADQEQQTLIDAFMTKDREKGFDLQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILKE
FFSMYDSLKNNSPVQLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRTADGNYKADQVSFSLAPDMV
EKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSVISGRPSAIDGIESMVGLFINTVPVRIRSAEGITFSSLVKA
VQEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYPVQLHQALSVESENDEGALKLSDISMSEQTNYDFNIVIVPG
ESFYIKFSYNADVYEREEMLRIQGHLKQALDCILTNPDVAVSDINIVPPEEQQVIQLFNETERPYVNKTIPQLFEEQAHK
TPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSGDIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAERLSFL
LKDSQAAQLLIEEDLISLIPPSYEGNTITIEHTESYQTEAPNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANTLQWRRE
EYSMTEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADDA
KSLRIVTFAGEAVTPDLLELNQIICPSAELANEYGPTENSVATTILRHLNKKERITIGHPIRNTKVFVLHGNQMQPIGAA
GELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQA
PGVKEAAVLARDVSAEEKELVAYIVPEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTSV
TYMAPRTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPLSEVFSYPTVESMAVKLMSLKE
HAFTQIEPADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLNRQRLRSVLTELVNRHEALRTVFVLDRDEPV
QIIYPEMAFDLKELEMESEQMLESAIETFIKPFYLSSGPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLY
CGKELPALNLHYKDFAVWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFRGGTIEVNIDKDMADELHRL
MAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSKPEGHKTFSSYLHDIRHLALTA
YEHQDYPFEELADKLDTNREVNRNPLFDAMLVLQSSEDFRFEVPGLSISSVTPKHDISKFDLTLHAEEHLSGIRCRFEYS
TALFEEETITQWASYFIELVKGVTADTEMRISNMQLLPAAERRLLLEKMGQYAAYPRNENIVSLFEKQVAQYPEHIAVVC
GHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRSPDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKLL
LTERGLNKPADYTGHILYIDECENNSIPADVNIEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNHE
DVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLLLKKERVTVLNQTPTAFYGLMLEDQNHTDHLNIRYV
IFGGEALQPGLLQSWNEKYPHTDLINMYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPGE
LYIGGEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYPM
IKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKLDQKALPEPEKQAYT
ADDISPRNEIETVMAEIWEELLNVDELGVSANFFKLGGDSIKALQVCARLKQRGFETTVREMFEHQTLGELSARVRKDVR
AIDQGPVEGEITWTPIQQWFFSQSLESHHFNQSVMIYRAERFDEAALRKVLKSLVTHHDALRIVCRHEDGRQVQINRGID
LSDEELYALELFDVKDSLTEARNTIEEAASRMQEHIRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFST
AYKQAVSGESIKLPQKTDSYLTYSQRIADYSISRQVQREAAYWDECENRHIQPIPKDNDAASNTFKDTEVIDFELSRHHT
ELLLTAAHKAYSTEMNDILLTALGLALQKWTGNNQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDKE
ERLGHLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNAFEVSDIKPGNEISPNWERPYA
LDISGAVSSGCLNMHIIYNRFQFEEKTIQTFSRHFKQTLENIIEHCTGKENQEWSASDFTDEDLTLDELSEIMGAVNKL

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Tyr and Thr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Thr residue is further converted to the D-allo-isomer form. The activation sit

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains

Homologues:

Organism=Homo sapiens, GI45580730, Length=620, Percent_Identity=26.2903225806452, Blast_Score=152, Evalue=5e-36,
Organism=Homo sapiens, GI156151445, Length=549, Percent_Identity=23.6794171220401, Blast_Score=134, Evalue=1e-30,
Organism=Homo sapiens, GI187761345, Length=576, Percent_Identity=23.4375, Blast_Score=128, Evalue=6e-29,
Organism=Homo sapiens, GI187761343, Length=576, Percent_Identity=23.4375, Blast_Score=128, Evalue=6e-29,
Organism=Homo sapiens, GI38505220, Length=505, Percent_Identity=22.7722772277228, Blast_Score=119, Evalue=4e-26,
Organism=Homo sapiens, GI28416953, Length=551, Percent_Identity=23.049001814882, Blast_Score=116, Evalue=2e-25,
Organism=Homo sapiens, GI157311624, Length=511, Percent_Identity=22.8962818003914, Blast_Score=114, Evalue=2e-24,
Organism=Homo sapiens, GI157311622, Length=511, Percent_Identity=22.8962818003914, Blast_Score=114, Evalue=2e-24,
Organism=Homo sapiens, GI42544132, Length=509, Percent_Identity=22.0039292730845, Blast_Score=110, Evalue=2e-23,
Organism=Homo sapiens, GI122937307, Length=506, Percent_Identity=22.1343873517787, Blast_Score=109, Evalue=4e-23,
Organism=Homo sapiens, GI58082049, Length=514, Percent_Identity=22.568093385214, Blast_Score=104, Evalue=1e-21,
Organism=Homo sapiens, GI38524616, Length=541, Percent_Identity=23.1053604436229, Blast_Score=96, Evalue=4e-19,
Organism=Homo sapiens, GI115511026, Length=510, Percent_Identity=20.9803921568627, Blast_Score=87, Evalue=3e-16,
Organism=Homo sapiens, GI13236579, Length=474, Percent_Identity=21.9409282700422, Blast_Score=77, Evalue=2e-13,
Organism=Escherichia coli, GI1786801, Length=1059, Percent_Identity=26.8177525967894, Blast_Score=343, Evalue=8e-95,
Organism=Escherichia coli, GI1788107, Length=545, Percent_Identity=25.3211009174312, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI145693145, Length=539, Percent_Identity=23.191094619666, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1790505, Length=529, Percent_Identity=24.007561436673, Blast_Score=124, Evalue=9e-29,
Organism=Escherichia coli, GI221142682, Length=515, Percent_Identity=24.2718446601942, Blast_Score=122, Evalue=4e-28,
Organism=Escherichia coli, GI1786810, Length=526, Percent_Identity=25.2851711026616, Blast_Score=117, Evalue=8e-27,
Organism=Escherichia coli, GI1786529, Length=557, Percent_Identity=22.8007181328546, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789201, Length=371, Percent_Identity=23.989218328841, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788595, Length=493, Percent_Identity=22.5152129817444, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=1160, Percent_Identity=23.2758620689655, Blast_Score=194, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17556356, Length=1148, Percent_Identity=23.8675958188153, Blast_Score=181, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17557194, Length=504, Percent_Identity=26.984126984127, Blast_Score=129, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17538037, Length=507, Percent_Identity=23.6686390532544, Blast_Score=123, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994703, Length=531, Percent_Identity=24.105461393597, Blast_Score=120, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994690, Length=531, Percent_Identity=24.105461393597, Blast_Score=120, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994694, Length=531, Percent_Identity=24.105461393597, Blast_Score=120, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17531443, Length=528, Percent_Identity=23.1060606060606, Blast_Score=112, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32563687, Length=533, Percent_Identity=23.4521575984991, Blast_Score=108, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17560140, Length=507, Percent_Identity=23.2741617357002, Blast_Score=107, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560308, Length=551, Percent_Identity=22.8675136116152, Blast_Score=106, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17558820, Length=472, Percent_Identity=23.9406779661017, Blast_Score=104, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71983001, Length=540, Percent_Identity=22.037037037037, Blast_Score=94, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982997, Length=540, Percent_Identity=22.037037037037, Blast_Score=94, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=537, Percent_Identity=22.9050279329609, Blast_Score=87, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32564420, Length=469, Percent_Identity=23.6673773987207, Blast_Score=87, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551278, Length=626, Percent_Identity=22.0447284345048, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564422, Length=469, Percent_Identity=23.6673773987207, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=366, Percent_Identity=23.7704918032787, Blast_Score=83, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534440, Length=528, Percent_Identity=21.5909090909091, Blast_Score=83, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=749, Percent_Identity=27.1028037383178, Blast_Score=248, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6319264, Length=532, Percent_Identity=23.8721804511278, Blast_Score=123, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319699, Length=537, Percent_Identity=22.7188081936685, Blast_Score=109, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323182, Length=537, Percent_Identity=22.7188081936685, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24648676, Length=641, Percent_Identity=29.4851794071763, Blast_Score=235, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24581924, Length=538, Percent_Identity=25.092936802974, Blast_Score=132, Evalue=4e-30,
Organism=Drosophila melanogaster, GI62472339, Length=539, Percent_Identity=23.0055658627087, Blast_Score=114, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24667955, Length=539, Percent_Identity=23.0055658627087, Blast_Score=114, Evalue=8e-25,
Organism=Drosophila melanogaster, GI18859661, Length=525, Percent_Identity=24, Blast_Score=103, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667959, Length=383, Percent_Identity=24.5430809399478, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550496, Length=566, Percent_Identity=22.9681978798587, Blast_Score=98, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45552801, Length=566, Percent_Identity=22.9681978798587, Blast_Score=97, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582852, Length=589, Percent_Identity=25.2971137521222, Blast_Score=93, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355181, Length=498, Percent_Identity=23.8955823293173, Blast_Score=89, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281364798, Length=557, Percent_Identity=22.0825852782765, Blast_Score=87, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24583465, Length=557, Percent_Identity=22.0825852782765, Blast_Score=86, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24583463, Length=557, Percent_Identity=22.0825852782765, Blast_Score=86, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656500, Length=497, Percent_Identity=22.3340040241449, Blast_Score=79, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356441, Length=451, Percent_Identity=23.9467849223947, Blast_Score=77, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356947, Length=368, Percent_Identity=24.1847826086957, Blast_Score=74, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281365686, Length=322, Percent_Identity=25.4658385093168, Blast_Score=69, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPSB_BACSU (P39846)

Other databases:

- EMBL:   Z34883
- EMBL:   AL009126
- PIR:   I40457
- RefSeq:   NP_389715.1
- ProteinModelPortal:   P39846
- EnsemblBacteria:   EBBACT00000003627
- GeneID:   939993
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18330
- NMPDR:   fig|224308.1.peg.1837
- GenoList:   BSU18330
- GeneTree:   EBGT00070000031957
- HOGENOM:   HBG547964
- OMA:   VLLHRYN
- PhylomeDB:   P39846
- ProtClustDB:   CLSK887368
- BioCyc:   BSUB:BSU18330-MONOMER
- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR006162
- Gene3D:   G3DSA:1.10.1200.10
- TIGRFAMs:   TIGR01733
- TIGRFAMs:   TIGR01720

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; SSF47336 ACP_like

EC number: 2.7.7.- [C]

Molecular weight: Translated: 290168; Mature: 290037

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50075 ACP_DOMAIN; PS00455 AMP_BINDING; PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNLCVDSFQKSLNLLVSR
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECEEEEECHHHHHHHHHHHHHHHHH
YDIFRTIFIKEVPDLTGPQQVVLSNRELTVYREDISRLADQEQQTLIDAFMTKDREKGFD
HHHHHHHHHHHCCCCCCCHHEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
LQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILKEFFSMYDSLKNNSPVQLGST
CCCCCHHEEEEEECCCCCEEEEEEECEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
VPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRTADGNYKADQVSFSLAPDM
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHEEEEECCHHH
VEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSVISGRPSAIDGIESMVGLFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
NTVPVRIRSAEGITFSSLVKAVQEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENY
HCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHEEEECCC
PVQLHQALSVESENDEGALKLSDISMSEQTNYDFNIVIVPGESFYIKFSYNADVYEREEM
CHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHH
LRIQGHLKQALDCILTNPDVAVSDINIVPPEEQQVIQLFNETERPYVNKTIPQLFEEQAH
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
KTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSGDIVAVMMGRSMEMPAALLGIW
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
KAGGAYMPLDPHFPAERLSFLLKDSQAAQLLIEEDLISLIPPSYEGNTITIEHTESYQTE
HCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
APNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANTLQWRREEYSMTEQDISLHLFSYVFD
CCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADD
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCC
AKSLRIVTFAGEAVTPDLLELNQIICPSAELANEYGPTENSVATTILRHLNKKERITIGH
CCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECC
PIRNTKVFVLHGNQMQPIGAAGELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRT
CCCCCEEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLARDVSAEEKE
CCCCCCCCCCHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
LVAYIVPEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTS
EEEEEECCCCCCHHHHHHHHHHCCCHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCE
VTYMAPRTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPL
EEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCH
SEVFSYPTVESMAVKLMSLKEHAFTQIEPADQRDVYPLSFSQKRLYALHQLADDSTGYNM
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
PAVLELRGNLNRQRLRSVLTELVNRHEALRTVFVLDRDEPVQIIYPEMAFDLKELEMESE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEECCHHHHHHHHHHHHHH
QMLESAIETFIKPFYLSSGPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDL
HHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEEHHHHHHCCCHHHHHHHHHHHH
YCGKELPALNLHYKDFAVWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPD
HCCCCCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
FRGGTIEVNIDKDMADELHRLMAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRP
CCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
HADLERVIGMFVNTLAMRSKPEGHKTFSSYLHDIRHLALTAYEHQDYPFEELADKLDTNR
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
EVNRNPLFDAMLVLQSSEDFRFEVPGLSISSVTPKHDISKFDLTLHAEEHLSGIRCRFEY
CCCCCCHHHHHHHHCCCCCCEEECCCCEECCCCCCCCCCEEEEEEEEHHHCCCEEEEEEH
STALFEEETITQWASYFIELVKGVTADTEMRISNMQLLPAAERRLLLEKMGQYAAYPRNE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEECCHHHHHHHHHHHHHHHCCCCCC
NIVSLFEKQVAQYPEHIAVVCGHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRS
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
PDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKLLLTERGLNKPADYTGHILYI
CHHHHHHHHHHHCCCCCCCCCCCCCHHHHHEEECCCCCEEEEEECCCCCCCCCCCEEEEE
DECENNSIPADVNIEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNH
EECCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHCCCCEEECC
EDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLLLKKERVTVLNQTPT
HHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHEEEECCCCC
AFYGLMLEDQNHTDHLNIRYVIFGGEALQPGLLQSWNEKYPHTDLINMYGITETTVHVTF
CEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCCCCHHEECCCCEEEEEEEE
KKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDELT
HHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCCCCHHHHH
ADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYP
HHHHHCCCCCCCCCEEECHHHHHHHCCCCCHHHHCCCHHHHHCCCEEEHHHHHHHHHHCC
MIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIP
CHHHHHHEEECCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHCCHHHEEECCEE
VTVNGKLDQKALPEPEKQAYTADDISPRNEIETVMAEIWEELLNVDELGVSANFFKLGGD
EEECCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCCEEEECCC
SIKALQVCARLKQRGFETTVREMFEHQTLGELSARVRKDVRAIDQGPVEGEITWTPIQQW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHH
FFSQSLESHHFNQSVMIYRAERFDEAALRKVLKSLVTHHDALRIVCRHEDGRQVQINRGI
HHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCHHEEEEEECCCCCEEEEECCC
DLSDEELYALELFDVKDSLTEARNTIEEAASRMQEHIRLETGPLLHAGLFRTENGDHLFL
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHEEECCCCCEEEE
TIHHLVVDAVSWRILFEDFSTAYKQAVSGESIKLPQKTDSYLTYSQRIADYSISRQVQRE
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AAYWDECENRHIQPIPKDNDAASNTFKDTEVIDFELSRHHTELLLTAAHKAYSTEMNDIL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LTALGLALQKWTGNNQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDK
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCCH
EERLGHLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHCCCCCHHHHHCCC
FEVSDIKPGNEISPNWERPYALDISGAVSSGCLNMHIIYNRFQFEEKTIQTFSRHFKQTL
EEEECCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHH
ENIIEHCTGKENQEWSASDFTDEDLTLDELSEIMGAVNKL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNLCVDSFQKSLNLLVSR
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECEEEEECHHHHHHHHHHHHHHHHH
YDIFRTIFIKEVPDLTGPQQVVLSNRELTVYREDISRLADQEQQTLIDAFMTKDREKGFD
HHHHHHHHHHHCCCCCCCHHEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
LQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILKEFFSMYDSLKNNSPVQLGST
CCCCCHHEEEEEECCCCCEEEEEEECEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
VPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRTADGNYKADQVSFSLAPDM
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHEEEEECCHHH
VEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSVISGRPSAIDGIESMVGLFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
NTVPVRIRSAEGITFSSLVKAVQEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENY
HCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHEEEECCC
PVQLHQALSVESENDEGALKLSDISMSEQTNYDFNIVIVPGESFYIKFSYNADVYEREEM
CHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHH
LRIQGHLKQALDCILTNPDVAVSDINIVPPEEQQVIQLFNETERPYVNKTIPQLFEEQAH
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
KTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSGDIVAVMMGRSMEMPAALLGIW
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
KAGGAYMPLDPHFPAERLSFLLKDSQAAQLLIEEDLISLIPPSYEGNTITIEHTESYQTE
HCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
APNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANTLQWRREEYSMTEQDISLHLFSYVFD
CCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEVMTADD
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHCCCC
AKSLRIVTFAGEAVTPDLLELNQIICPSAELANEYGPTENSVATTILRHLNKKERITIGH
CCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECC
PIRNTKVFVLHGNQMQPIGAAGELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRT
CCCCCEEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLARDVSAEEKE
CCCCCCCCCCHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
LVAYIVPEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNTS
EEEEEECCCCCCHHHHHHHHHHCCCHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCE
VTYMAPRTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPL
EEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCH
SEVFSYPTVESMAVKLMSLKEHAFTQIEPADQRDVYPLSFSQKRLYALHQLADDSTGYNM
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
PAVLELRGNLNRQRLRSVLTELVNRHEALRTVFVLDRDEPVQIIYPEMAFDLKELEMESE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEECCHHHHHHHHHHHHHH
QMLESAIETFIKPFYLSSGPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDL
HHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEEHHHHHHCCCHHHHHHHHHHHH
YCGKELPALNLHYKDFAVWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPD
HCCCCCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
FRGGTIEVNIDKDMADELHRLMAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRP
CCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
HADLERVIGMFVNTLAMRSKPEGHKTFSSYLHDIRHLALTAYEHQDYPFEELADKLDTNR
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
EVNRNPLFDAMLVLQSSEDFRFEVPGLSISSVTPKHDISKFDLTLHAEEHLSGIRCRFEY
CCCCCCHHHHHHHHCCCCCCEEECCCCEECCCCCCCCCCEEEEEEEEHHHCCCEEEEEEH
STALFEEETITQWASYFIELVKGVTADTEMRISNMQLLPAAERRLLLEKMGQYAAYPRNE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEECCHHHHHHHHHHHHHHHCCCCCC
NIVSLFEKQVAQYPEHIAVVCGHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRS
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
PDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKLLLTERGLNKPADYTGHILYI
CHHHHHHHHHHHCCCCCCCCCCCCCHHHHHEEECCCCCEEEEEECCCCCCCCCCCEEEEE
DECENNSIPADVNIEEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNH
EECCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHCCCCEEECC
EDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPQAFRLLLKKERVTVLNQTPT
HHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHEEEECCCCC
AFYGLMLEDQNHTDHLNIRYVIFGGEALQPGLLQSWNEKYPHTDLINMYGITETTVHVTF
CEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCCCCHHEECCCCEEEEEEEE
KKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDELT
HHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCCCCHHHHH
ADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYP
HHHHHCCCCCCCCCEEECHHHHHHHCCCCCHHHHCCCHHHHHCCCEEEHHHHHHHHHHCC
MIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIP
CHHHHHHEEECCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHCCHHHEEECCEE
VTVNGKLDQKALPEPEKQAYTADDISPRNEIETVMAEIWEELLNVDELGVSANFFKLGGD
EEECCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCCEEEECCC
SIKALQVCARLKQRGFETTVREMFEHQTLGELSARVRKDVRAIDQGPVEGEITWTPIQQW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHH
FFSQSLESHHFNQSVMIYRAERFDEAALRKVLKSLVTHHDALRIVCRHEDGRQVQINRGI
HHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCHHEEEEEECCCCCEEEEECCC
DLSDEELYALELFDVKDSLTEARNTIEEAASRMQEHIRLETGPLLHAGLFRTENGDHLFL
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHEEECCCCCEEEE
TIHHLVVDAVSWRILFEDFSTAYKQAVSGESIKLPQKTDSYLTYSQRIADYSISRQVQRE
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AAYWDECENRHIQPIPKDNDAASNTFKDTEVIDFELSRHHTELLLTAAHKAYSTEMNDIL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LTALGLALQKWTGNNQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDK
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCCH
EERLGHLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHCCCCCHHHHHCCC
FEVSDIKPGNEISPNWERPYALDISGAVSSGCLNMHIIYNRFQFEEKTIQTFSRHFKQTL
EEEECCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHH
ENIIEHCTGKENQEWSASDFTDEDLTLDELSEIMGAVNKL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377; 10471562