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The map label for this gene is pbpX

Identifier: 16078758

GI number: 16078758

Start: 1765859

End: 1767034

Strand: Direct

Name: pbpX

Synonym: BSU16950

Alternate gene names: 16078758

Gene position: 1765859-1767034 (Clockwise)

Preceding gene: 255767389

Following gene: 16078759

Centisome position: 41.89

GC content: 39.54

Gene sequence:

>1176_bases
ATGACAAGCCCAACCCGCAGAAGAACTGCGAAACGCAGACGGAGAAAACTAAATAAAAGAGGAAAACTGTTGTTTGGTCT
TTTAGCAGTGATGGTTTGCATTACGATTTGGAATGCTCTTCATCGAAATAGTGAAGAAAACGAACCATCTCAAGAAACTG
CAGCGGTTTCAAATACCGATCAGAAAAAAGAGGTCAAAAAGAAAACTGCCAAAAAATCAGAGGAACAAATCAAAACAGTG
GATCGAAACCAAAAAATCAGCAATTATTTAAAAGAGATCGGTTTCAGCGGAACAGCCATGATTGTCAGAAATGGAGAAAT
CGTAACAAATAAAGGTTTTGGCTATGCTGACCGTAAACACTACATTCAAAATAATCCATTGACATCTTTTTATGTCGGTT
CATCACAAAAAGCGCTGATTGCAACTGCTATTTTGCAGCTTGAGGAAAAGGGGAAACTTCAGACAAGTGATCCGGTAAGC
ACGTATTTACCTCATTTTCCCAACGGACAAACGATTACTTTGAAGAATCTGCTTACACATACATCGGGGATAAACGGACA
TATTGAAGGAAACGGCGCCATTACTCCGGACGATTTAATAAAAGATATAGAACTTCAGGGAATCAAACGTCAGCCGGGCG
TATGGGACTACAAGGATTCCAACTATTCTGTTCTTGCTTATATTATTGCTGAAGTAAGCGGTGAGCCCTATGAACAGTAC
ATAAAGAATCATATTTTTAAACCTGCGGGAATGACGCATGCAGGCTTTTACAAAACATATGAAAAAGAACCTTATCCTGC
CGTCGGGTATAAGATGGAGGGCAGCAAAACAGTTACACCGTATATACCTGATTTATCCCAGCTGTATGGAGCGGGTGATA
TTTATATGAGCGCTATAGATATGTACAAATTTGACCAAGCGCTGATAGACGGAAAACTGTATTCGCAAAAAAGCTATGAA
AAGATGTTTACGCCAGGGAGCAGCTCCACATACGGCATGGGATTTTATGTTGCTCCCGGAAGCTATTCAAACCATGGTGT
TATGCCGGGCTTCAATATCTTGAACAGCTTTAGCAAATCTGGGCAAACCATTGTTATTTTGTTCTCAAACATTCAAAATA
ATGCTAAATTGGGCCAAGTGAACAATAAAATATACCAGCTTCTAAATCAAGAATGA

Upstream 100 bases:

>100_bases
AAAATGATAAAAATATTGCTTTTTTTGACAACTTTTTTAGGGCTTTATTCGTCTAACAAAACGTGTGCAAAATGGAATTT
ATTTTGGGAGGAAAAAATGA

Downstream 100 bases:

>100_bases
TTGGCGATCTTCTTTTGGATGAATTGCATTCGGCACGTGAAAAGAAGACTGGCCTGCAAACGTTAAGATGGCAAGCTTGA
CAAGTATTTCCGACACATTT

Product: penicillin-binding endopeptidase X

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNSEENEPSQETAAVSNTDQKKEVKKKTAKKSEEQIKTV
DRNQKISNYLKEIGFSGTAMIVRNGEIVTNKGFGYADRKHYIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVS
TYLPHFPNGQTITLKNLLTHTSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYKDSNYSVLAYIIAEVSGEPYEQY
IKNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSKTVTPYIPDLSQLYGAGDIYMSAIDMYKFDQALIDGKLYSQKSYE
KMFTPGSSSTYGMGFYVAPGSYSNHGVMPGFNILNSFSKSGQTIVILFSNIQNNAKLGQVNNKIYQLLNQE

Sequences:

>Translated_391_residues
MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNSEENEPSQETAAVSNTDQKKEVKKKTAKKSEEQIKTV
DRNQKISNYLKEIGFSGTAMIVRNGEIVTNKGFGYADRKHYIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVS
TYLPHFPNGQTITLKNLLTHTSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYKDSNYSVLAYIIAEVSGEPYEQY
IKNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSKTVTPYIPDLSQLYGAGDIYMSAIDMYKFDQALIDGKLYSQKSYE
KMFTPGSSSTYGMGFYVAPGSYSNHGVMPGFNILNSFSKSGQTIVILFSNIQNNAKLGQVNNKIYQLLNQE
>Mature_390_residues
TSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNSEENEPSQETAAVSNTDQKKEVKKKTAKKSEEQIKTVD
RNQKISNYLKEIGFSGTAMIVRNGEIVTNKGFGYADRKHYIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVST
YLPHFPNGQTITLKNLLTHTSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYKDSNYSVLAYIIAEVSGEPYEQYI
KNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSKTVTPYIPDLSQLYGAGDIYMSAIDMYKFDQALIDGKLYSQKSYEK
MFTPGSSSTYGMGFYVAPGSYSNHGVMPGFNILNSFSKSGQTIVILFSNIQNNAKLGQVNNKIYQLLNQE

Specific function: Binds Penicillin And Contributes To The Normal Morphology Of Escherichia Coli. [C]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=Localizes to the division septum during vegetative growth, and accumulates at the prespore during sporulation

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family

Homologues:

Organism=Escherichia coli, GI1786574, Length=277, Percent_Identity=24.9097472924188, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082101, Length=391, Percent_Identity=23.0179028132992, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533026, Length=376, Percent_Identity=22.0744680851064, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PBPX_BACSU (O31773)

Other databases:

- EMBL:   AL009126
- PIR:   C69673
- RefSeq:   NP_389577.1
- ProteinModelPortal:   O31773
- SMR:   O31773
- EnsemblBacteria:   EBBACT00000000078
- GeneID:   939677
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16950
- NMPDR:   fig|224308.1.peg.1698
- GenoList:   BSU16950
- GeneTree:   EBGT00070000031931
- HOGENOM:   HBG337850
- OMA:   YLIGSAQ
- PhylomeDB:   O31773
- ProtClustDB:   CLSK887319
- BioCyc:   BSUB:BSU16950-MONOMER
- InterPro:   IPR012338
- InterPro:   IPR001466

Pfam domain/function: PF00144 Beta-lactamase; SSF56601 PBP_transp_fold

EC number: NA

Molecular weight: Translated: 43858; Mature: 43727

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf08cbec)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNSEENEPSQETAAVSNTD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCH
QKKEVKKKTAKKSEEQIKTVDRNQKISNYLKEIGFSGTAMIVRNGEIVTNKGFGYADRKH
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCCCHHH
YIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVSTYLPHFPNGQTITLKNLLTH
HHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEEHHHHHHH
TSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYKDSNYSVLAYIIAEVSGEPYEQY
CCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCHHHHH
IKNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSKTVTPYIPDLSQLYGAGDIYMSAID
HHHHCCCCCCCCHHHHHHHCCCCCCCCCCEEECCCCEECCCCCCHHHHHCCCHHHHHHHH
MYKFDQALIDGKLYSQKSYEKMFTPGSSSTYGMGFYVAPGSYSNHGVMPGFNILNSFSKS
HHHHHHHHHCCHHHCCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCC
GQTIVILFSNIQNNAKLGQVNNKIYQLLNQE
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNSEENEPSQETAAVSNTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCH
QKKEVKKKTAKKSEEQIKTVDRNQKISNYLKEIGFSGTAMIVRNGEIVTNKGFGYADRKH
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCCCHHH
YIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVSTYLPHFPNGQTITLKNLLTH
HHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEEHHHHHHH
TSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYKDSNYSVLAYIIAEVSGEPYEQY
CCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCHHHHH
IKNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSKTVTPYIPDLSQLYGAGDIYMSAID
HHHHCCCCCCCCHHHHHHHCCCCCCCCCCEEECCCCEECCCCCCHHHHHCCCHHHHHHHH
MYKFDQALIDGKLYSQKSYEKMFTPGSSSTYGMGFYVAPGSYSNHGVMPGFNILNSFSKS
HHHHHHHHHCCHHHCCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCC
GQTIVILFSNIQNNAKLGQVNNKIYQLLNQE
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377