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The map label for this gene is spoIIGA

Identifier: 16078595

GI number: 16078595

Start: 1603779

End: 1604708

Strand: Direct

Name: spoIIGA

Synonym: BSU15310

Alternate gene names: 16078595

Gene position: 1603779-1604708 (Clockwise)

Preceding gene: 16078594

Following gene: 255767354

Centisome position: 38.04

GC content: 39.46

Gene sequence:

>930_bases
GTGAAAATCTATTTAGATGTCATTTGGCTGTTAAACTTTTGTTTTGATGCACTTTTGCTTTTGCTCACGGCATTTATTTT
AAAACGGCATGTAAAAAAAAGAAGACTGGTAGGCGGAGCGTTCATCGGTTCCAGTATTGTCCTTTTGATGTTTACTCCTT
TTTCGCCGATTGTTGAACATCCGGCTGGGAAGCTAGCTTTTTCAGTTGTGATTGTGGTGGTGACATTTGGCTTTAAAAGA
TTTCGGTTTTTCTTTCAAAATTTGTTTTCCTTTTATTTTGCCACTTTTTTAATGGGGGGAGGAATTATCGGAGCCCATTC
TTTGCTGCAGTCAAATTCTATTGTTCAAAACGGTGTCATGATTACCAATCAAACAGGGTTTGGAGACCCGATCAGCTGGT
TGTTTATTGTTGGTGGCTTTCCAGCATTATGGTTTTTTTCTAAAAGAAGAATTGAAGATATTGAAACAAAAAACATTCAA
TATGAGGAACGAGTCAGCGTGCAGGCAGATTTGGGCAGCCAAACACTTCATGTCAGAGGCCTGATTGATTCCGGTAACCA
GCTGTACGATCCTCTTACAAAAACACCGGTAATGATCATTTACATTGATAAACTGGAGCCGATTTTCGGAACAGCCGAAA
CGATGATCATTCGAAACACAGACCCATTGGAAGCCATCGAACAGCTCGATGATTCCTTTCGCTTTTTAGATAAAATGAGG
TTGATTCCATACAGGGGAGTTGGTCAGCAAAATCAATTTTTATTATGCGTTAAACCGGATCACGTAACGATTATGACAAA
AGAAGAAATGATTTCTGCAGATAAATGTTTAATCGGTATCAGCACAACAAAGCTGTCGGCAGATGGAGAGTTTGACGCGA
TTATTCATCCGAAAATGCTTTCGGGCAAGGCTGTCAAACACGTTTCATAA

Upstream 100 bases:

>100_bases
TTCCTCTCAACATTAATTGACAGACTTTCCCACAGAGCTTGCTTTATACTTATGAAGCAAGAAGGGGAACAGCGTGAGGC
AAGAAAGAAAGGAGTCAGAT

Downstream 100 bases:

>100_bases
TGTTCGCAAATGTCCGTTACTTATCATACTCAAACGGCGTGACATTTAGAAGGGAGAGGAAGATGAAAAAACTGAAATTA
CGGTTGACGCACCTCTGGTA

Product: protease processing pro-sigma-E

Products: NA

Alternate protein names: Stage II sporulation protein GA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGSSIVLLMFTPFSPIVEHPAGKLAFSVVIVVVTFGFKR
FRFFFQNLFSFYFATFLMGGGIIGAHSLLQSNSIVQNGVMITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQ
YEERVSVQADLGSQTLHVRGLIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIRNTDPLEAIEQLDDSFRFLDKMR
LIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKCLIGISTTKLSADGEFDAIIHPKMLSGKAVKHVS

Sequences:

>Translated_309_residues
MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGSSIVLLMFTPFSPIVEHPAGKLAFSVVIVVVTFGFKR
FRFFFQNLFSFYFATFLMGGGIIGAHSLLQSNSIVQNGVMITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQ
YEERVSVQADLGSQTLHVRGLIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIRNTDPLEAIEQLDDSFRFLDKMR
LIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKCLIGISTTKLSADGEFDAIIHPKMLSGKAVKHVS
>Mature_309_residues
MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGSSIVLLMFTPFSPIVEHPAGKLAFSVVIVVVTFGFKR
FRFFFQNLFSFYFATFLMGGGIIGAHSLLQSNSIVQNGVMITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQ
YEERVSVQADLGSQTLHVRGLIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIRNTDPLEAIEQLDDSFRFLDKMR
LIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKCLIGISTTKLSADGEFDAIIHPKMLSGKAVKHVS

Specific function: Seems to be responsible for the processing of the sigma E factor (spoIIGB)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U4 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP2G_BACSU (P13801)

Other databases:

- EMBL:   X17344
- EMBL:   AL009126
- PIR:   S08224
- RefSeq:   NP_389414.1
- ProteinModelPortal:   P13801
- MEROPS:   U04.001
- EnsemblBacteria:   EBBACT00000001146
- GeneID:   939984
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU15310
- NMPDR:   fig|224308.1.peg.1533
- GenoList:   BSU15310
- GeneTree:   EBGT00050000002893
- HOGENOM:   HBG313622
- OMA:   SEPREMK
- ProtClustDB:   CLSK2460920
- BioCyc:   BSUB:BSU15310-MONOMER
- GO:   GO:0006508
- InterPro:   IPR005081
- TIGRFAMs:   TIGR02854

Pfam domain/function: PF03419 Peptidase_U4

EC number: NA

Molecular weight: Translated: 34858; Mature: 34858

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: ACT_SITE 183-183

Signals:

None

Transmembrane regions:

HASH(0xeffd5e0)-; HASH(0xd8f8d94)-; HASH(0xe912598)-; HASH(0xf00457c)-; HASH(0xd50c690)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGSSIVLLMFTPFSPIVEH
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHC
PAGKLAFSVVIVVVTFGFKRFRFFFQNLFSFYFATFLMGGGIIGAHSLLQSNSIVQNGVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCEE
ITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQYEERVSVQADLGSQTLHVRG
EEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCEEEEEE
LIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIRNTDPLEAIEQLDDSFRFLDKMR
EECCCCHHHCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
LIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKCLIGISTTKLSADGEFDAIIHPKML
CCCCCCCCCCCCEEEEECCCCEEEEEHHHHHCCCCEEEEEEEEEECCCCCCCEEECCHHC
SGKAVKHVS
CCCCCCCCH
>Mature Secondary Structure
MKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRLVGGAFIGSSIVLLMFTPFSPIVEH
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHC
PAGKLAFSVVIVVVTFGFKRFRFFFQNLFSFYFATFLMGGGIIGAHSLLQSNSIVQNGVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCEE
ITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDIETKNIQYEERVSVQADLGSQTLHVRG
EEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCEEEEEE
LIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAETMIIRNTDPLEAIEQLDDSFRFLDKMR
EECCCCHHHCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
LIPYRGVGQQNQFLLCVKPDHVTIMTKEEMISADKCLIGISTTKLSADGEFDAIIHPKML
CCCCCCCCCCCCEEEEECCCCEEEEEHHHHHCCCCEEEEEEEEEECCCCCCCEEECCHHC
SGKAVKHVS
CCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3125985; 2106671; 9384377