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The map label for this gene is ctaC

Identifier: 16078553

GI number: 16078553

Start: 1560466

End: 1561536

Strand: Direct

Name: ctaC

Synonym: BSU14890

Alternate gene names: 16078553

Gene position: 1560466-1561536 (Clockwise)

Preceding gene: 16078552

Following gene: 255767339

Centisome position: 37.02

GC content: 43.23

Gene sequence:

>1071_bases
ATGGTAAAGCATTGGCGTCTTATTTTATTATTAGCCTTAGTGCCGCTTCTATTAAGCGGATGTGGAAAACCTTTTTTATC
CACGCTCAAGCCTGCTGGCGAGGTGGCTGATAAACAGTATGACCTGACAGTGCTCAGCACATTGATTATGGTGGTTGTTG
TTGCAGTAGTATCTGTTATCTTCTTTTATGTGATTGTGAGATTCAGAAGATCACGGGTCGGTGAGAACACGATACCGAAA
CAGGTAGAGGGGAATAAATTTTTAGAAATCACATGGACCGTGATCCCGATTTTGCTGCTCATTATTCTTGTGATTCCTGT
TGTATTATATACGCTGGAGCTAGCGGACACATCACCAATGGATAAAAAAGGCCGCAAAGCTGAGGATGCTCTTGTAGTCA
ATGTTAGGGCAAATTTATACTGGTGGGAGTTTGAGTACCCTGATTACGGCATTATCACAAGCCAGGAGCTGATTGTACCG
ACAGATCAGCGTGTATATTTTAATTTAAAAGCCTCTGATGTAAAACATTCCTTCTGGATTCCTTCAGTTGGAGGAAAACT
TGATACGAATACGGATAATGAAAATAAGTTCTTCCTGACATTTGATTCAAAACGAAGCAAAGAGGCAGGAGATATGTTTT
TTGGGAAGTGTGCAGAGCTTTGCGGCCCTTCACATGCGCTGATGGATTTTAAGGTGAAGACGATGTCTGCAAAAGAATTT
CAGGGCTGGACAAAAGAAATGAAGAACTATAAGTCTACAGCAGAGAGCGATTTGGCTAAGCAGGGTGAAGAACTGTTTAA
AGAGAAAAACTGCCTGAGCTGCCATGCGGTAGAGCCGAATGATAAGCGTGCAGAAGCCGCTAGAACGGCACCTAACTTGG
CGACCTTCGGTGAAAGGACAAAAGTGGCAGGGGTGAAAGAGGCCAACAAAGAAAATGTGAAGGCTTGGCTGAAGGACCCT
GACAGCATAAAGCCGGGGAACAAAATGACAGGCACATATCCAAAGCTCTCAGACAGCGAAACAAATGCGCTTTATGAATA
CTTAAAAGGCTTAAAAGCGGAAAGCAAGTAG

Upstream 100 bases:

>100_bases
AGAAGAGGAAATGTAAGTGCTTTATTGGTGATAGGTTGGATGGCGATAGATTTCGATCCGCTTTCCGCCTTTGTATTGAC
CAGAAAAGGGGTTGGGTGAA

Downstream 100 bases:

>100_bases
GGAAGAAAGGGAGATATTGGGGGAGGTCACATATGTTGAATGCGCTTACAGAAAAGCGGACGCGCGGATCTATGCTTTGG
GATTATTTGACGACGGTGGA

Product: cytochrome caa3 oxidase subunit II

Products: NA

Alternate protein names: Caa-3605 subunit 2; Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVIFFYVIVRFRRSRVGENTIPK
QVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPMDKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVP
TDQRVYFNLKASDVKHSFWIPSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEF
QGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERTKVAGVKEANKENVKAWLKDP
DSIKPGNKMTGTYPKLSDSETNALYEYLKGLKAESK

Sequences:

>Translated_356_residues
MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVIFFYVIVRFRRSRVGENTIPK
QVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPMDKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVP
TDQRVYFNLKASDVKHSFWIPSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEF
QGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERTKVAGVKEANKENVKAWLKDP
DSIKPGNKMTGTYPKLSDSETNALYEYLKGLKAESK
>Mature_356_residues
MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVIFFYVIVRFRRSRVGENTIPK
QVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPMDKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVP
TDQRVYFNLKASDVKHSFWIPSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEF
QGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERTKVAGVKEANKENVKAWLKDP
DSIKPGNKMTGTYPKLSDSETNALYEYLKGLKAESK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain

Homologues:

Organism=Escherichia coli, GI1786635, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6226540, Length=225, Percent_Identity=23.5555555555556, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX2_BACSU (P24011)

Other databases:

- EMBL:   X54140
- EMBL:   Z98682
- EMBL:   AL009126
- PIR:   S14396
- RefSeq:   NP_389372.1
- ProteinModelPortal:   P24011
- SMR:   P24011
- EnsemblBacteria:   EBBACT00000002242
- GeneID:   936789
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14890
- NMPDR:   fig|224308.1.peg.1491
- GenoList:   BSU14890
- GeneTree:   EBGT00050000001583
- HOGENOM:   HBG661753
- OMA:   DVKHSFW
- PhylomeDB:   P24011
- ProtClustDB:   CLSK2460916
- BioCyc:   BSUB:BSU14890-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- Gene3D:   G3DSA:1.10.287.90
- Gene3D:   G3DSA:2.60.40.420
- Gene3D:   G3DSA:1.10.760.10
- PANTHER:   PTHR22888
- PRINTS:   PR01166
- TIGRFAMs:   TIGR02866

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C; SSF49503 Cupredoxin; SSF81464 Cyt_c_oxidase_II-like_TM; SSF46626 Cytochrome_c

EC number: =1.9.3.1

Molecular weight: Translated: 40095; Mature: 40095

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00078 COX2; PS50857 COX2_CUA; PS50999 COX2_TM; PS51007 CYTC; PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: BINDING 271-271 BINDING 274-274

Signals:

None

Transmembrane regions:

HASH(0xefbea48)-; HASH(0xcab42ac)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVI
CCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFYVIVRFRRSRVGENTIPKQVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPM
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVPTDQRVYFNLKASDVKHSFWI
CCCCCCCCCEEEEEEEEEEEEEEECCCCCCEEECCCEEECCCCEEEEEEECCCCCCEEEC
PSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEF
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEEECCCHHHH
QGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCCCHHHCCCHH
KVAGVKEANKENVKAWLKDPDSIKPGNKMTGTYPKLSDSETNALYEYLKGLKAESK
HHCCCHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVI
CCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFYVIVRFRRSRVGENTIPKQVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPM
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVPTDQRVYFNLKASDVKHSFWI
CCCCCCCCCEEEEEEEEEEEEEEECCCCCCEEECCCEEECCCCEEEEEEECCCCCCEEEC
PSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEF
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEEECCCHHHH
QGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCCCHHHCCCHH
KVAGVKEANKENVKAWLKDPDSIKPGNKMTGTYPKLSDSETNALYEYLKGLKAESK
HHCCCHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377