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The map label for this gene is ctaB

Identifier: 16078552

GI number: 16078552

Start: 1559309

End: 1560226

Strand: Direct

Name: ctaB

Synonym: BSU14880

Alternate gene names: 16078552

Gene position: 1559309-1560226 (Clockwise)

Preceding gene: 16078550

Following gene: 16078553

Centisome position: 36.99

GC content: 43.46

Gene sequence:

>918_bases
ATGGCTAACTCCAGAATCTTAAATGATACAGCTATAGACGGACAAATTGAAGAAACAACGGCATGGAAAGATTTTCTGTC
CCTTATTAAAATAGGGATCGTCAATTCTAACCTCATCACGACTTTCACTGGAATGTGGCTTGCACTGCATATATCCGGTT
TAAGTTTTTTAGGCAATATAAACACCGTTCTTCTTACGTTAATCGGGTCTTCACTGATTATTGCGGGCTCCTGCGCGATC
AATAACTGGTATGACCGGGACATTGACCATCTTATGGAGCGTACGAAAGTAAGACCGACGGTTACGGGTAAAATTCAGCC
GAGTCAGGCGTTATGGTCTGGAATTTTGCTGGTTGCTTTAGGATTGATCATGCTGCTGATGACAACTGTCATGGCTGCTG
TTATCGGTTTTATCGGAGTCTTTACGTATGTTGTATTGTACACAATGTGGACGAAACGCCGCTATACGATTAACACAGTA
GTAGGAAGCGTTTCCGGTGCAGTGCCGCCGCTTATTGGATGGACGGCAGTGGAAGGGAATATCGGTGTCGTAGCATGGGT
GTTATTCATGATTTTATTTATTTGGCAGATTCCTCACTTCTTAGCATTGGCTATTAAGAAAACTGAGGATTACAGAGCTG
CAAATATTCCGATGCTTCCTGTCGTATACGGATTTGAAGTGACAAAAAGACAAATTATTGTGTGGGTTGCGTGCCTGATG
CCGCTTCCGTTTTTCCTTGGTAGCCTGGGTCTTCCGATTGTCATTCTCGGCTTGCTGTTAAATATCGGCTGGCTGATTCT
TGGCTTAATGGGATTCCGCTCCAAGAATATCATGAAGTGGGCAACGCAGATGTTCGTTTACTCGCTTAACTACATGACAA
TCTATTTCGTTGCCATGGTTGTCTTGACGCTTTTCTAA

Upstream 100 bases:

>100_bases
AATATTTAATAGGATGTTTTTTTACAAGATGTTATCTTGTATGATAGAGTTGCAGGTTATTTTATTCTCCTGCGTTAGGT
TTGTAAGGGAGGTTTACGTT

Downstream 100 bases:

>100_bases
AAAATAGATATGATGCTTGTTTTATCGCTTCAAAATAAACGATGACAACTAGTAAATGCCGCCTTGACCTCTTGTTTAAT
CAGGCGGCTTTACTTTTATA

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase 2; Heme O synthase 2 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MANSRILNDTAIDGQIEETTAWKDFLSLIKIGIVNSNLITTFTGMWLALHISGLSFLGNINTVLLTLIGSSLIIAGSCAI
NNWYDRDIDHLMERTKVRPTVTGKIQPSQALWSGILLVALGLIMLLMTTVMAAVIGFIGVFTYVVLYTMWTKRRYTINTV
VGSVSGAVPPLIGWTAVEGNIGVVAWVLFMILFIWQIPHFLALAIKKTEDYRAANIPMLPVVYGFEVTKRQIIVWVACLM
PLPFFLGSLGLPIVILGLLLNIGWLILGLMGFRSKNIMKWATQMFVYSLNYMTIYFVAMVVLTLF

Sequences:

>Translated_305_residues
MANSRILNDTAIDGQIEETTAWKDFLSLIKIGIVNSNLITTFTGMWLALHISGLSFLGNINTVLLTLIGSSLIIAGSCAI
NNWYDRDIDHLMERTKVRPTVTGKIQPSQALWSGILLVALGLIMLLMTTVMAAVIGFIGVFTYVVLYTMWTKRRYTINTV
VGSVSGAVPPLIGWTAVEGNIGVVAWVLFMILFIWQIPHFLALAIKKTEDYRAANIPMLPVVYGFEVTKRQIIVWVACLM
PLPFFLGSLGLPIVILGLLLNIGWLILGLMGFRSKNIMKWATQMFVYSLNYMTIYFVAMVVLTLF
>Mature_304_residues
ANSRILNDTAIDGQIEETTAWKDFLSLIKIGIVNSNLITTFTGMWLALHISGLSFLGNINTVLLTLIGSSLIIAGSCAIN
NWYDRDIDHLMERTKVRPTVTGKIQPSQALWSGILLVALGLIMLLMTTVMAAVIGFIGVFTYVVLYTMWTKRRYTINTVV
GSVSGAVPPLIGWTAVEGNIGVVAWVLFMILFIWQIPHFLALAIKKTEDYRAANIPMLPVVYGFEVTKRQIIVWVACLMP
LPFFLGSLGLPIVILGLLLNIGWLILGLMGFRSKNIMKWATQMFVYSLNYMTIYFVAMVVLTLF

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=161, Percent_Identity=36.6459627329193, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786631, Length=286, Percent_Identity=36.3636363636364, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71998235, Length=156, Percent_Identity=32.6923076923077, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325085, Length=160, Percent_Identity=33.125, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19921064, Length=165, Percent_Identity=34.5454545454545, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33946; Mature: 33815

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSRILNDTAIDGQIEETTAWKDFLSLIKIGIVNSNLITTFTGMWLALHISGLSFLGNI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
NTVLLTLIGSSLIIAGSCAINNWYDRDIDHLMERTKVRPTVTGKIQPSQALWSGILLVAL
HHHHHHHHCCHHEEECCHHCCCCHHCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHH
GLIMLLMTTVMAAVIGFIGVFTYVVLYTMWTKRRYTINTVVGSVSGAVPPLIGWTAVEGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCEEEEECCC
IGVVAWVLFMILFIWQIPHFLALAIKKTEDYRAANIPMLPVVYGFEVTKRQIIVWVACLM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
PLPFFLGSLGLPIVILGLLLNIGWLILGLMGFRSKNIMKWATQMFVYSLNYMTIYFVAMV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLTLF
HHHHC
>Mature Secondary Structure 
ANSRILNDTAIDGQIEETTAWKDFLSLIKIGIVNSNLITTFTGMWLALHISGLSFLGNI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
NTVLLTLIGSSLIIAGSCAINNWYDRDIDHLMERTKVRPTVTGKIQPSQALWSGILLVAL
HHHHHHHHCCHHEEECCHHCCCCHHCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHH
GLIMLLMTTVMAAVIGFIGVFTYVVLYTMWTKRRYTINTVVGSVSGAVPPLIGWTAVEGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCEEEEECCC
IGVVAWVLFMILFIWQIPHFLALAIKKTEDYRAANIPMLPVVYGFEVTKRQIIVWVACLM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
PLPFFLGSLGLPIVILGLLLNIGWLILGLMGFRSKNIMKWATQMFVYSLNYMTIYFVAMV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLTLF
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA