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The map label for this gene is ctaA

Identifier: 16078551

GI number: 16078551

Start: 1558034

End: 1558954

Strand: Reverse

Name: ctaA

Synonym: BSU14870

Alternate gene names: 16078551

Gene position: 1558954-1558034 (Counterclockwise)

Preceding gene: 16078558

Following gene: 16078546

Centisome position: 36.98

GC content: 42.67

Gene sequence:

>921_bases
ATGAATAAAGCATTAAAAGCTCTCGGTGTTCTGACGACATTTGTCATGCTAATTGTTTTAATCGGGGGTGCCCTCGTTAC
AAAAACAGGTTCCGGCCAAGGATGCGGCAGACAGTGGCCGCTGTGTCACGGCCGTTTTTTCCCTGAACTGAATCCGGCTT
CAATTATTGAATGGAGCCACCGATTCGCAAGCGGAATCTCTATTATCCTTGTGCTAAGCCTTGCGTTTTGGTCATGGAGA
AAAATCACGCCGATTTTTCGTGAAACAACGTTTCTCGCGATCATGTCAATTATCTTTTTATTTCTTCAGGCATTGCTTGG
CGCATTGGCTGTCGTATTCGGTTCGAACGCGCTGATTATGGCGCTTCACTTCGGCATCTCATTAATTTCTTTTGCTTCAG
TGCTTATTTTAACATTGCTCATATTTGAAGCTGATAAATCAGTCAGAACACTGGTTAAGCCGCTTCAAATCGGCAAAAAG
ATGCAATTTCACATGATAGGAATTTTAATATATTCCTATATCGTTGTGTATACAGGCGCATATGTAAGACACACTGAATC
AAGTCTGGCATGTCCTAATGTGCCGCTGTGCAGCCCGCTGAACAATGGACTTCCGACCCAATTCCATGAATGGGTGCAAA
TGGGCCACAGAGCAGCAGCCTTACTTTTATTTGTATGGATTATTGTTGCCGCTGTTCATGCTATTACTTCCTATAAAGAT
CAAAAACAGATCTTTTGGGGATGGATCTCATGTCTTATTTTCATTACATTACAGGCACTGTCCGGTATTATGATCGTATA
CTCTGAACTGGCTCTGGGCTTTGCACTTGCCCACTCGTTCTTTATTGCCTGTCTGTTTGGCGTTCTATGCTACTTCTTAT
TATTGATTGCTCGTTTCCGTTATGAATCCAGGCAATCATAA

Upstream 100 bases:

>100_bases
TTGTGAACAAAAGGCTCTGGGAATTGCCACAAAACACATATTCGCTTACACTTGGAACGTATATAAAATTGCAGCAGTAT
GTTAAGAAGGTGAATATTGT

Downstream 100 bases:

>100_bases
GGACTCAAGACCAAAGCCTTAGGCGGCTTTGGTCTTTTTTATGTCTTGTTTTTTGGCGCTTTATGCGTTTCAATCGCCAG
CCTTCGCCGAACTTGATGAT

Product: heme-A synthase

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSHRFASGISIILVLSLAFWSWR
KITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIMALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKK
MQFHMIGILIYSYIVVYTGAYVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKD
QKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFRYESRQS

Sequences:

>Translated_306_residues
MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSHRFASGISIILVLSLAFWSWR
KITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIMALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKK
MQFHMIGILIYSYIVVYTGAYVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKD
QKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFRYESRQS
>Mature_306_residues
MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSHRFASGISIILVLSLAFWSWR
KITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIMALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKK
MQFHMIGILIYSYIVVYTGAYVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKD
QKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFRYESRQS

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group. Also involved in the sporulation

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_BACSU (P12946)

Other databases:

- EMBL:   M23915
- EMBL:   Z98682
- EMBL:   AL009126
- PIR:   A33960
- RefSeq:   NP_389370.1
- ProteinModelPortal:   P12946
- IntAct:   P12946
- EnsemblBacteria:   EBBACT00000002146
- GeneID:   937030
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14870
- NMPDR:   fig|224308.1.peg.1489
- GenoList:   BSU14870
- GeneTree:   EBGT00050000001315
- HOGENOM:   HBG313632
- OMA:   MGHRVAA
- ProtClustDB:   CLSK2752390
- BioCyc:   BSUB:BSU14870-MONOMER
- HAMAP:   MF_01664
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 34085; Mature: 34085

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: BINDING 278-278

Signals:

None

Transmembrane regions:

HASH(0xe6c6a68)-; HASH(0xefcac48)-; HASH(0xe32e9d8)-; HASH(0xefc4ab0)-; HASH(0xefc4d08)-; HASH(0xefc1d9c)-; HASH(0xefc1e8c)-; HASH(0xe201e74)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSH
CCHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RFASGISIILVLSLAFWSWRKITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKKMQFHMIGILIYSYIVVYTGA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCH
YVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKD
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YESRQS
HHCCCH
>Mature Secondary Structure
MNKALKALGVLTTFVMLIVLIGGALVTKTGSGQGCGRQWPLCHGRFFPELNPASIIEWSH
CCHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RFASGISIILVLSLAFWSWRKITPIFRETTFLAIMSIIFLFLQALLGALAVVFGSNALIM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALHFGISLISFASVLILTLLIFEADKSVRTLVKPLQIGKKMQFHMIGILIYSYIVVYTGA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCH
YVRHTESSLACPNVPLCSPLNNGLPTQFHEWVQMGHRAAALLLFVWIIVAAVHAITSYKD
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QKQIFWGWISCLIFITLQALSGIMIVYSELALGFALAHSFFIACLFGVLCYFLLLIARFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YESRQS
HHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2549006; 9384377