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The map label for this gene is ccpC

Identifier: 16078478

GI number: 16078478

Start: 1486045

End: 1486926

Strand: Direct

Name: ccpC

Synonym: BSU14140

Alternate gene names: 16078478

Gene position: 1486045-1486926 (Clockwise)

Preceding gene: 16078477

Following gene: 16078479

Centisome position: 35.25

GC content: 41.95

Gene sequence:

>882_bases
ATGCAGCTTCAAGAGCTTCATATGCTCGTAGTTTTAGCTGAGGAATTAAATATGAGAAAGGCGGCAGAACGGCTTTTTGT
ATCTCAGCCGGCTTTATCTCAGCGCTTACAAACCATTGAAAAGGCGTGGGGAACAAAAATCTTTTTAAGATCTCAAAAAG
GATTAACGGTAACGCCCGCCGGTGAGAAAATCATTCAGTTTGCGAATGATGTGACATTAGAGCAGGAAAGAATAAGAGAA
AATATTGACGAGCTTGAAGGTGAAATTCACGGCACATTGAAGCTTGCCGTCGCCTCCATAATCGGTCAGCATTGGCTCCC
TAAAGTCCTGAAGACGTATGTGGAAAAGTATCCGAATGCAAAGATCTCGCTCATAACCGGGTGGAGCAGCGAAATGCTGA
AAAGCTTGTATGAGGATCAGGTTCATATCGGCATTATAAGAGGCAACCCTGAGTGGAAGGGGCGCAAAGATTACTTAATG
ACAGATCATCTGTATTTAGTGGATACTGAAATTTCCTGCATCGAAGATATTGCCCATACAGAACGTCCGTTTATCCAGTT
TAAAAGTGACAGCACTTATTTTCAGGAAATTCAGCACTGGTGGCATCAAAAATTTAAAACGTCGCCGAAACAGACGATAT
TGGTTGATCAGATTGAAACGTGCAAACAGATGGCGCTGCACGGAATCGGTTATGCCATTTTGCCGTCTGTTACCCTTCAA
AATGAAGATAAAGTGAATAAAATGCCTCTTTTAGACATGAAAGGGCATCCGATCGGTCGGGATACATGGTTATTAGGTTA
TGAGCCTGCCTTTGAACTGAAACAAGTTCAAGCTTTTGTACAAGTGATAAAGGATATGCTGGATCAGGAAAATCCATTTT
AA

Upstream 100 bases:

>100_bases
GCATACATAATTTAAACGAGAATAGGGCTTGAATAAGAAACTAAGATTTTATTAGAATGGGAGATAAGAAAAACTTATTG
ATAACAAAAAGGAGGACGAC

Downstream 100 bases:

>100_bases
AGACAGCGAGGTGCTGTCTTTTTTTTATTTATCTGTTGACAATGAAAATCATTATCATTTAAAGTGATACATATGATATT
GAAAATCATTATCAACTAAT

Product: transcriptional repressor of citB and citZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MQLQELHMLVVLAEELNMRKAAERLFVSQPALSQRLQTIEKAWGTKIFLRSQKGLTVTPAGEKIIQFANDVTLEQERIRE
NIDELEGEIHGTLKLAVASIIGQHWLPKVLKTYVEKYPNAKISLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLM
TDHLYLVDTEISCIEDIAHTERPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLQ
NEDKVNKMPLLDMKGHPIGRDTWLLGYEPAFELKQVQAFVQVIKDMLDQENPF

Sequences:

>Translated_293_residues
MQLQELHMLVVLAEELNMRKAAERLFVSQPALSQRLQTIEKAWGTKIFLRSQKGLTVTPAGEKIIQFANDVTLEQERIRE
NIDELEGEIHGTLKLAVASIIGQHWLPKVLKTYVEKYPNAKISLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLM
TDHLYLVDTEISCIEDIAHTERPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLQ
NEDKVNKMPLLDMKGHPIGRDTWLLGYEPAFELKQVQAFVQVIKDMLDQENPF
>Mature_293_residues
MQLQELHMLVVLAEELNMRKAAERLFVSQPALSQRLQTIEKAWGTKIFLRSQKGLTVTPAGEKIIQFANDVTLEQERIRE
NIDELEGEIHGTLKLAVASIIGQHWLPKVLKTYVEKYPNAKISLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLM
TDHLYLVDTEISCIEDIAHTERPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLQ
NEDKVNKMPLLDMKGHPIGRDTWLLGYEPAFELKQVQAFVQVIKDMLDQENPF

Specific function: This Protein Activates The Transcription Of The Ilvc Gene In The Presence Of Acetolactate Or Acetohydroxybutyrate. Ilvy Is Also A Negative Regulator Of Its Own Expression. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=25.4980079681275, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=313, Percent_Identity=24.9201277955272, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787601, Length=161, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=23.265306122449, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=148, Percent_Identity=25, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=299, Percent_Identity=22.4080267558528, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788296, Length=147, Percent_Identity=27.891156462585, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790399, Length=302, Percent_Identity=21.8543046357616, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789506, Length=148, Percent_Identity=25, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786401, Length=146, Percent_Identity=26.7123287671233, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKUM_BACSU (O34827)

Other databases:

- EMBL:   AJ222587
- EMBL:   AL009126
- PIR:   B69866
- RefSeq:   NP_389297.1
- ProteinModelPortal:   O34827
- IntAct:   O34827
- EnsemblBacteria:   EBBACT00000000227
- GeneID:   939197
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14140
- NMPDR:   fig|224308.1.peg.1416
- GenoList:   BSU14140
- GeneTree:   EBGT00050000000807
- HOGENOM:   HBG338345
- OMA:   CKQMALH
- ProtClustDB:   CLSK887221
- BioCyc:   BSUB:BSU14140-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33913; Mature: 33913

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLQELHMLVVLAEELNMRKAAERLFVSQPALSQRLQTIEKAWGTKIFLRSQKGLTVTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCEECCC
GEKIIQFANDVTLEQERIRENIDELEGEIHGTLKLAVASIIGQHWLPKVLKTYVEKYPNA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KISLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLMTDHLYLVDTEISCIEDIAHT
EEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCEEEEECCHHHHHHHHHC
ERPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLQ
CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCHHHHCCCEEC
NEDKVNKMPLLDMKGHPIGRDTWLLGYEPAFELKQVQAFVQVIKDMLDQENPF
CCCCCCCCCEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQLQELHMLVVLAEELNMRKAAERLFVSQPALSQRLQTIEKAWGTKIFLRSQKGLTVTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCEECCC
GEKIIQFANDVTLEQERIRENIDELEGEIHGTLKLAVASIIGQHWLPKVLKTYVEKYPNA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KISLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLMTDHLYLVDTEISCIEDIAHT
EEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCEEEEECCHHHHHHHHHC
ERPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLQ
CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCHHHHCCCEEC
NEDKVNKMPLLDMKGHPIGRDTWLLGYEPAFELKQVQAFVQVIKDMLDQENPF
CCCCCCCCCEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377