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The map label for this gene is cheV

Identifier: 16078465

GI number: 16078465

Start: 1473605

End: 1474516

Strand: Direct

Name: cheV

Synonym: BSU14010

Alternate gene names: 16078465

Gene position: 1473605-1474516 (Clockwise)

Preceding gene: 16078463

Following gene: 16078470

Centisome position: 34.96

GC content: 38.93

Gene sequence:

>912_bases
TTGTCGTTACAACAATACGAAATTTTATTGGATTCTGGTACAAATGAATTAGAAATTGTGAAGTTTGGCGTGGGTGAAAA
TGCTTTCGGAATTAACGTCATGAAGGTAAGAGAAATTATTCAGCCTGTCGAGGTGACATCAGTGCCTCACTCCCATCAGC
ATGTAGAAGGAATGATTAAACTCAGAGGAGAAATCCTCCCTGTGATCAGTCTCTTCTCATTTTTTGGAGTAGAGCCTGAA
GGATCAAAAGATGAGAAATATATCGTGACTGAATTTAATAAACGGAAAATTGTTTTTCATGTCGGCTCTGTTTCTCAAAT
TCACAGAGTATCCTGGGAAGCGATTGAAAAGCCGACATCGTTAAATCAAGGAATGGAGCGGCACCTTACCGGTATTATTA
AGCTCGAAGACCTGATGATCTTTTTGCCTGACTATGAAAAAATTATTTATGACATTGAATCAGATTCAGGTGTTGACACG
TATAATATGCATACCGAGGGCTTCGATGAAAGAAGAACTGATAAAAAGCTTATCATTGTAGAGGACTCACCGCTTTTGAT
GCGCCTCTTGCAGGATGAATTAAAAGAAGCAGGGTACAACAATATCGCTTCGTTTGAAAATGGAAAAGAGGCATATGAAT
ACATTATGAACCTTGCTGAAAACGAAACTGATTTATCAAAACAGATTGATATGATCATCACTGATATTGAAATGCCAAAA
ATGGACGGACACAGGCTCACAAAGCTGCTGAAGGAAAATCCGAAAAGCTCAGATGTGCCGGTTATGATTTTCTCATCGTT
AATTACGGATGATCTGCGTCACCGCGGCGAAGTTGTAGGCGCAGATGAGCAAATCAGCAAGCCTGAGATCAGTGATTTGA
TTAAAAAAGTGGATACGTATGTTATTGAATAA

Upstream 100 bases:

>100_bases
GTTGCCTTCGGAATTCGATTTTGAAGAGCTGCCATTCACTTTTTACAAATTACGCCGATATATACAGTACAATACTGAAT
GCGAATAGCGAGGGATTGAA

Downstream 100 bases:

>100_bases
ATAAAAACAGCCGTTGCCAGAAAGAGGCACGGCTGTTTTTATTTTAAAAGTAACTCTCGCCAAGTTTTTTAAAGACCGGT
TTATGGTAAGCTGGCTGCTG

Product: coupling protein and response regulator for CheA activity in response to attractants (chemotaxis)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVEVTSVPHSHQHVEGMIKLRGEILPVISLFSFFGVEPE
GSKDEKYIVTEFNKRKIVFHVGSVSQIHRVSWEAIEKPTSLNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDT
YNMHTEGFDERRTDKKLIIVEDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNLAENETDLSKQIDMIITDIEMPK
MDGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRGEVVGADEQISKPEISDLIKKVDTYVIE

Sequences:

>Translated_303_residues
MSLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVEVTSVPHSHQHVEGMIKLRGEILPVISLFSFFGVEPE
GSKDEKYIVTEFNKRKIVFHVGSVSQIHRVSWEAIEKPTSLNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDT
YNMHTEGFDERRTDKKLIIVEDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNLAENETDLSKQIDMIITDIEMPK
MDGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRGEVVGADEQISKPEISDLIKKVDTYVIE
>Mature_302_residues
SLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVEVTSVPHSHQHVEGMIKLRGEILPVISLFSFFGVEPEG
SKDEKYIVTEFNKRKIVFHVGSVSQIHRVSWEAIEKPTSLNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDTY
NMHTEGFDERRTDKKLIIVEDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNLAENETDLSKQIDMIITDIEMPKM
DGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRGEVVGADEQISKPEISDLIKKVDTYVIE

Specific function: Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW function together to couple CheA activation to methyl-accepting chemotaxis protein receptor status and possible CheA-dependent phosphoryl

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEV_BACSU (P37599)

Other databases:

- EMBL:   Z29584
- EMBL:   U05345
- EMBL:   AJ222587
- EMBL:   AL009126
- PIR:   A55592
- RefSeq:   NP_389284.1
- ProteinModelPortal:   P37599
- EnsemblBacteria:   EBBACT00000002015
- GeneID:   939239
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14010
- NMPDR:   fig|224308.1.peg.1403
- GenoList:   BSU14010
- GeneTree:   EBGT00050000000107
- HOGENOM:   HBG489472
- OMA:   EVQHRSV
- ProtClustDB:   CLSK887212
- BioCyc:   BSUB:BSU14010-MONOMER
- GO:   GO:0005622
- GO:   GO:0006935
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR001789
- SMART:   SM00260
- SMART:   SM00448

Pfam domain/function: PF01584 CheW; PF00072 Response_reg; SSF50341 CheW; SSF52172 CheY_like

EC number: 2.7.3.- [C]

Molecular weight: Translated: 34634; Mature: 34503

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50851 CHEW; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVEVTSVPHSHQHVEGMIK
CCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
LRGEILPVISLFSFFGVEPEGSKDEKYIVTEFNKRKIVFHVGSVSQIHRVSWEAIEKPTS
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHCCCCH
LNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDTYNMHTEGFDERRTDKKLIIV
HHHHHHHHHHHEEEEEEEEEECCCHHHEEEECCCCCCCCEEECCCCCCCHHCCCCEEEEE
EDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNLAENETDLSKQIDMIITDIEMPK
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCC
MDGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRGEVVGADEQISKPEISDLIKKVDTY
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHH
VIE
CCC
>Mature Secondary Structure 
SLQQYEILLDSGTNELEIVKFGVGENAFGINVMKVREIIQPVEVTSVPHSHQHVEGMIK
CCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
LRGEILPVISLFSFFGVEPEGSKDEKYIVTEFNKRKIVFHVGSVSQIHRVSWEAIEKPTS
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHCCCCH
LNQGMERHLTGIIKLEDLMIFLPDYEKIIYDIESDSGVDTYNMHTEGFDERRTDKKLIIV
HHHHHHHHHHHEEEEEEEEEECCCHHHEEEECCCCCCCCEEECCCCCCCHHCCCCEEEEE
EDSPLLMRLLQDELKEAGYNNIASFENGKEAYEYIMNLAENETDLSKQIDMIITDIEMPK
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCC
MDGHRLTKLLKENPKSSDVPVMIFSSLITDDLRHRGEVVGADEQISKPEISDLIKKVDTY
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHH
VIE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8169223; 9384377; 8169224