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The map label for this gene is stoA

Identifier: 16078448

GI number: 16078448

Start: 1450638

End: 1451135

Strand: Direct

Name: stoA

Synonym: BSU13840

Alternate gene names: 16078448

Gene position: 1450638-1451135 (Clockwise)

Preceding gene: 16078447

Following gene: 16078449

Centisome position: 34.41

GC content: 41.97

Gene sequence:

>498_bases
ATGTTGACGAAGCGCTTGCTTACTATATACATTATGTTATTAGGGTTGATTGCATGGTTTCCAGGTGCGGCACAAGCTGA
GGAAAAACAGCCTGCTGTTCCCGCTGTTTTTCTTATGAAAACGATAGAAGGGGAGGACATCTCGATTCCGAATAAAGGGC
AAAAAACAATTCTCCATTTTTGGACGTCATGGTGCCCGCCCTGCAAAAAGGAGCTTCCACAGTTTCAATCGTTTTATGAT
GCCCATCCATCCGACAGTGTAAAGCTGGTAACGGTGAATTTAGTGAATTCGGAACAAAATCAGCAAGTCGTTGAAGACTT
TATTAAAGCAAACAAGCTGACGTTTCCGATTGTCCTTGACTCAAAAGGGGAATTGATGAAGGAGTATCATATCATCACGA
TCCCAACATCATTTTTGCTGAATGAAAAGGGAGAAATTGAAAAAACAAAAATTGGCCCGATGACAGCGGAACAACTGAAG
GAATGGACGGAAGAATAG

Upstream 100 bases:

>100_bases
TATCTGTATTTCTTACGGGAGGGACCAGAACGCCGCGAATTGAAGGATGATAAAGGAACAGCAGGGGCAAGCTAATTGAA
AAGCATGAAAGGAAGATTCC

Downstream 100 bases:

>100_bases
CTGAGAGCATAGACTCTCAGCTTTTTTCATATAGAGAAGAAGTGAATAAACATTAATGATAATTATTATCAAAAAGAAAT
TAAAATAATTATAATTGAAA

Product: thiol-disulfide isomerase

Products: NA

Alternate protein names: Stage IV sporulation protein H

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHFWTSWCPPCKKELPQFQSFYD
AHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLK
EWTEE

Sequences:

>Translated_165_residues
MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHFWTSWCPPCKKELPQFQSFYD
AHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLK
EWTEE
>Mature_165_residues
MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHFWTSWCPPCKKELPQFQSFYD
AHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLK
EWTEE

Specific function: Thiol-disulfide oxidoreductase with a reductive function, involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis, or in thiol/disulfide bond i

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Spore wall, spore outer membrane (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): STOA_BACSU (O31687)

Other databases:

- EMBL:   AL009126
- PIR:   E69869
- RefSeq:   NP_389267.1
- PDB:   3ERW
- PDBsum:   3ERW
- ProteinModelPortal:   O31687
- SMR:   O31687
- EnsemblBacteria:   EBBACT00000002889
- GeneID:   936262
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13840
- NMPDR:   fig|224308.1.peg.1386
- GenoList:   BSU13840
- GeneTree:   EBGT00070000032289
- HOGENOM:   HBG493509
- OMA:   IAVNEFD
- ProtClustDB:   CLSK887204
- BioCyc:   BSUB:BSU13840-MONOMER
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 18807; Mature: 18807

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHF
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
WTSWCPPCKKELPQFQSFYDAHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLD
HHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEC
SKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLKEWTEE
CCCHHHHHEEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHF
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
WTSWCPPCKKELPQFQSFYDAHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLD
HHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEC
SKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLKEWTEE
CCCHHHHHEEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377