Click here to switch to the map view.

The map label for this gene is dppC

Identifier: 16078359

GI number: 16078359

Start: 1362174

End: 1363136

Strand: Direct

Name: dppC

Synonym: BSU12940

Alternate gene names: 16078359

Gene position: 1362174-1363136 (Clockwise)

Preceding gene: 16078358

Following gene: 16078360

Centisome position: 32.31

GC content: 49.95

Gene sequence:

>963_bases
GTGAATCTCCCTGTACAAACGGATGAACGCCAGCCAGAACAGCACAATCAGGTGCCTGATGAGTGGTTTGTCTTGAATCA
GGAAAAAAATCGGGAAGCCGATTCGGTCAAGCGGCCGAGTTTGTCATACACGCAGGATGCCTGGAGGAGGCTGAAAAAAA
ATAAATTAGCGATGGCCGGACTCTTTATTCTTTTATTTCTTTTTGTCATGGCAGTTATCGGGCCCTTTTTATCGCCCCAT
AGTGTCGTACGCCAATCGCTGACAGAACAAAATCTTCCGCCCTCAGCCGATCATTGGTTCGGCACCGATGAACTCGGCCG
GGATGTGTTTACCCGAACATGGTATGGCGCGAGAATCTCGTTGTTTGTCGGCGTGATGGCAGCACTGATTGATTTTTTGA
TCGGTGTCATTTACGGAGGCGTTGCCGGCTATAAAGGCGGCAGGATTGACAGCATTATGATGCGGATTATCGAAGTGCTG
TACGGACTGCCGTATCTGCTTGTTGTCATTTTGCTGATGGTGCTCATGGGACCGGGACTGGGCACGATTATTGTGGCGCT
GACTGTGACCGGGTGGGTCGGCATGGCGAGAATTGTAAGAGGCCAGGTGCTTCAGATTAAAAATTATGAATATGTACTCG
CCTCGAAAACCTTTGGCGCGAAAACCTTTCGCATCATCCGGAAGAATTTGCTGCCGAATACTATGGGAGCGATCATCGTA
CAAATGACATTAACCGTACCTGCCGCCATATTCGCAGAATCATTTTTAAGCTTTCTCGGCCTGGGCATACAGGCTCCGTT
TGCAAGTTGGGGCGTGATGGCGAATGACGGCCTGCCTACGATTTTATCTGGGCATTGGTGGCGCCTGTTTTTTCCGGCCT
TTTTCATATCTCTGACGATGTACGCGTTTAATGTGCTGGGGGACGGATTGCAGGATGCGCTTGACCCTAAGCTGAGGAGG
TAG

Upstream 100 bases:

>100_bases
TTTTTTACAGCGTCATTCTGATTATCATGCTGTTTTTGGTCGATTTGGCCTACGGTCTCTTAGACCCGCGCATTAAACTG
CATAAGAAAGGGTGAAGCGT

Downstream 100 bases:

>100_bases
CTGTATGGAAAAAGTTCTGTCAGTCCAAAATCTGCACGTGTCTTTTACGACTTACGGCGGGACGGTTCAGGCGGTCAGAG
GGGTGAGCTTTGATTTGTAT

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYTQDAWRRLKKNKLAMAGLFILLFLFVMAVIGPFLSPH
SVVRQSLTEQNLPPSADHWFGTDELGRDVFTRTWYGARISLFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVL
YGLPYLLVVILLMVLMGPGLGTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTFGAKTFRIIRKNLLPNTMGAIIV
QMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMANDGLPTILSGHWWRLFFPAFFISLTMYAFNVLGDGLQDALDPKLRR

Sequences:

>Translated_320_residues
MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYTQDAWRRLKKNKLAMAGLFILLFLFVMAVIGPFLSPH
SVVRQSLTEQNLPPSADHWFGTDELGRDVFTRTWYGARISLFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVL
YGLPYLLVVILLMVLMGPGLGTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTFGAKTFRIIRKNLLPNTMGAIIV
QMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMANDGLPTILSGHWWRLFFPAFFISLTMYAFNVLGDGLQDALDPKLRR
>Mature_320_residues
MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYTQDAWRRLKKNKLAMAGLFILLFLFVMAVIGPFLSPH
SVVRQSLTEQNLPPSADHWFGTDELGRDVFTRTWYGARISLFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVL
YGLPYLLVVILLMVLMGPGLGTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTFGAKTFRIIRKNLLPNTMGAIIV
QMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMANDGLPTILSGHWWRLFFPAFFISLTMYAFNVLGDGLQDALDPKLRR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787498, Length=300, Percent_Identity=40.6666666666667, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=38.5767790262172, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787054, Length=298, Percent_Identity=36.241610738255, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789964, Length=302, Percent_Identity=37.4172185430464, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789889, Length=232, Percent_Identity=35.7758620689655, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787549, Length=286, Percent_Identity=30.4195804195804, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=32.3008849557522, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPPC_BACSU (P26904)

Other databases:

- EMBL:   X56678
- EMBL:   AJ002571
- EMBL:   AL009126
- EMBL:   M22907
- PIR:   S16649
- RefSeq:   NP_389177.1
- ProteinModelPortal:   P26904
- EnsemblBacteria:   EBBACT00000001960
- GeneID:   938038
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU12940
- NMPDR:   fig|224308.1.peg.1296
- GenoList:   BSU12940
- GeneTree:   EBGT00050000000641
- HOGENOM:   HBG729429
- OMA:   PTILSGH
- PhylomeDB:   P26904
- ProtClustDB:   CLSK887154
- BioCyc:   BSUB:BSU12940-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 35804; Mature: 35804

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdcab738)-; HASH(0xe59a8c4)-; HASH(0xb7042d4)-; HASH(0xe7222f8)-; HASH(0xb6cbbdc)-; HASH(0xc644c10)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYTQDAWRRLKKNKLAMAG
CCCCCCCCCCCCHHHCCCCCHHEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LFILLFLFVMAVIGPFLSPHSVVRQSLTEQNLPPSADHWFGTDELGRDVFTRTWYGARIS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVLYGLPYLLVVILLMVLMGPGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
GTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTFGAKTFRIIRKNLLPNTMGAIIV
HHHHHHHHHHHHHHHHHHHHCHHEEECCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHH
QMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMANDGLPTILSGHWWRLFFPAFFISLTM
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEECCCCCHHHCCCHHHHHHHHHHHHHHH
YAFNVLGDGLQDALDPKLRR
HHHHHHCCHHHHHCCCCCCH
>Mature Secondary Structure
MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYTQDAWRRLKKNKLAMAG
CCCCCCCCCCCCHHHCCCCCHHEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LFILLFLFVMAVIGPFLSPHSVVRQSLTEQNLPPSADHWFGTDELGRDVFTRTWYGARIS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVLYGLPYLLVVILLMVLMGPGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
GTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTFGAKTFRIIRKNLLPNTMGAIIV
HHHHHHHHHHHHHHHHHHHHCHHEEECCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHH
QMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMANDGLPTILSGHWWRLFFPAFFISLTM
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEECCCCCHHHCCCHHHHHHHHHHHHHHH
YAFNVLGDGLQDALDPKLRR
HHHHHHCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377; 3145906