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The map label for this gene is dppB

Identifier: 16078358

GI number: 16078358

Start: 1361242

End: 1362168

Strand: Direct

Name: dppB

Synonym: BSU12930

Alternate gene names: 16078358

Gene position: 1361242-1362168 (Clockwise)

Preceding gene: 255767301

Following gene: 16078359

Centisome position: 32.29

GC content: 46.39

Gene sequence:

>927_bases
TTGGCGCGATACATGATAAAGCGTTTTTGGGCAATGGCAGCTACGATTTTGGTGATTACCACCCTGACTTTTGTTCTCAT
GAAGGTCATTCCCGGATCTCCTTTTAACGAGGAGAGAGGCACAAATGAAGCCGTTCAAAAAAATCTCGAAGCCTACTATC
ACTTAGACGATCCTCTCATTTTCCAATACATTTTCTACTTAAAATCCATCATTACATTCGATTTCGGACCTTCAATTAAA
AAACCGTCGGACAGCGTAAATGATATGCTGGAACGCGGATTTCCCGTTTCCTTTGAGCTTGGGATGACAGCGATTGTCAT
TGCTGTGATTTCTGGGCTGGTGCTGGGCGTAATCGCTGCACTCCGCCGCAATGGCTTTTTGGACTACGCCGCGATGAGTC
TTGCAGTACTCGGCATCTCCATCCCGAATTTTATTCTGGCAACATTGCTCATTCAGCAATTTGCTGTCAATCTCAAACTA
TTTCCCGCTGCGACATGGACGAGCCCGATTCATATGGTGCTTCCGACCGCAGCGCTTGCTGTAGGGCCAATGGCGATCAT
TGCCAGGCTGACACGGTCGAGCATGGTCGAAGTTCTGACACAGGATTATATCCGCACAGCAAAAGCAAAAGGGCTTTCTC
CGTTCAAAATTATCGTAAAACACGCACTCAGAAATGCACTCATGCCCGTCATTACCGTCCTGGGCACACTCGTCGCCAGC
ATCTTAACAGGAAGCTTTGTCATTGAAAAAATCTTTGCCATTCCGGGAATGGGAAAATATTTTGTTGAAAGCATTAATCA
GCGGGACTACCCCGTGATTATGGGAACGACCGTTTTTTACAGCGTCATTCTGATTATCATGCTGTTTTTGGTCGATTTGG
CCTACGGTCTCTTAGACCCGCGCATTAAACTGCATAAGAAAGGGTGA

Upstream 100 bases:

>100_bases
CAATTTCAGGCGAAGGACATGCTTGAAGCCTATCAGGCGATGCTTGTCATGACTGAGCTTGCGATGCGGACATCATTCTG
CTAAAGGGGTGTTTTAGGCT

Downstream 100 bases:

>100_bases
AGCGTGTGAATCTCCCTGTACAAACGGATGAACGCCAGCCAGAACAGCACAATCAGGTGCCTGATGAGTGGTTTGTCTTG
AATCAGGAAAAAAATCGGGA

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MARYMIKRFWAMAATILVITTLTFVLMKVIPGSPFNEERGTNEAVQKNLEAYYHLDDPLIFQYIFYLKSIITFDFGPSIK
KPSDSVNDMLERGFPVSFELGMTAIVIAVISGLVLGVIAALRRNGFLDYAAMSLAVLGISIPNFILATLLIQQFAVNLKL
FPAATWTSPIHMVLPTAALAVGPMAIIARLTRSSMVEVLTQDYIRTAKAKGLSPFKIIVKHALRNALMPVITVLGTLVAS
ILTGSFVIEKIFAIPGMGKYFVESINQRDYPVIMGTTVFYSVILIIMLFLVDLAYGLLDPRIKLHKKG

Sequences:

>Translated_308_residues
MARYMIKRFWAMAATILVITTLTFVLMKVIPGSPFNEERGTNEAVQKNLEAYYHLDDPLIFQYIFYLKSIITFDFGPSIK
KPSDSVNDMLERGFPVSFELGMTAIVIAVISGLVLGVIAALRRNGFLDYAAMSLAVLGISIPNFILATLLIQQFAVNLKL
FPAATWTSPIHMVLPTAALAVGPMAIIARLTRSSMVEVLTQDYIRTAKAKGLSPFKIIVKHALRNALMPVITVLGTLVAS
ILTGSFVIEKIFAIPGMGKYFVESINQRDYPVIMGTTVFYSVILIIMLFLVDLAYGLLDPRIKLHKKG
>Mature_307_residues
ARYMIKRFWAMAATILVITTLTFVLMKVIPGSPFNEERGTNEAVQKNLEAYYHLDDPLIFQYIFYLKSIITFDFGPSIKK
PSDSVNDMLERGFPVSFELGMTAIVIAVISGLVLGVIAALRRNGFLDYAAMSLAVLGISIPNFILATLLIQQFAVNLKLF
PAATWTSPIHMVLPTAALAVGPMAIIARLTRSSMVEVLTQDYIRTAKAKGLSPFKIIVKHALRNALMPVITVLGTLVASI
LTGSFVIEKIFAIPGMGKYFVESINQRDYPVIMGTTVFYSVILIIMLFLVDLAYGLLDPRIKLHKKG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787497, Length=305, Percent_Identity=42.6229508196721, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=35.7771260997067, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787053, Length=305, Percent_Identity=37.3770491803279, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1789888, Length=311, Percent_Identity=35.048231511254, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=33.6391437308869, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788504, Length=365, Percent_Identity=27.9452054794521, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=30.8550185873606, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPPB_BACSU (P26903)

Other databases:

- EMBL:   X56678
- EMBL:   AJ002571
- EMBL:   AL009126
- PIR:   S16648
- RefSeq:   NP_389176.1
- ProteinModelPortal:   P26903
- EnsemblBacteria:   EBBACT00000000956
- GeneID:   939881
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU12930
- NMPDR:   fig|224308.1.peg.1295
- GenoList:   BSU12930
- GeneTree:   EBGT00050000000642
- HOGENOM:   HBG724229
- OMA:   PFNEERG
- PhylomeDB:   P26903
- ProtClustDB:   CLSK887153
- BioCyc:   BSUB:BSU12930-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 34056; Mature: 33925

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe4ce02c)-; HASH(0xc959340)-; HASH(0xd7205f8)-; HASH(0xdb705a4)-; HASH(0xdcab60c)-; HASH(0xcdda440)-; HASH(0xb49fcd8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHCCCCH
>Mature Secondary Structure 
ARYMIKRFWAMAATILVITTLTFVLMKVIPGSPFNEERGTNEAVQKNLEAYYHLDDPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH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CHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377