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The map label for this gene is yjbP

Identifier: 16078228

GI number: 16078228

Start: 1239387

End: 1240121

Strand: Reverse

Name: yjbP

Synonym: BSU11630

Alternate gene names: 16078228

Gene position: 1240121-1239387 (Counterclockwise)

Preceding gene: 16078239

Following gene: 16078223

Centisome position: 29.42

GC content: 46.53

Gene sequence:

>735_bases
ATGGCTTACGATATCATCAGCGATATTCATGGCTGCTATGACGAAATGACTGCATTAATCCAAAAGCTTGGCTATACAAT
CAAAAATGGAGTACCTGTCCATGAAGAAGGCAGGGTGCTTGTTTTTGCCGGAGATTTAACTGACAGAGGGCCCAAATCGA
TAGAGGTCATCCGATTTGTAGCCGGCGCTTACGAAAAAGGCGCTGTGCGTTATGTCCCGGGAAACCATTGCAATAAATTA
TATCGTTACTTAAAAGGAAATCCGGTAAAAGTGATGCATGGTCTCGAAACAACAGCGGCAGAGCTTGAGGAACTTTCCAA
AGATGAGAAAAAATCAGTCAGCGAACAGTTTATGAAGCTGTACGAAACAGCGCCGCTTTACGACATCTTACATAATGGAG
AATTAGTTGTCGCCCATGCTGGCATAAGAGCTGACGATATCGGCAAATATACCCGCAGAGTGAAGGACTTTGTGCTTTAC
GGTGACGTGACGGGTGAAACATATCCGGACGGCAGACCCATCAGGCGTGATTGGGCGGCAGCCTATAACGGAAAGGCTTG
GGTGGTATACGGTCATACACCTGTGAAAGAGCCTCGGAAGGTCAATCGCACCATCAACATTGATACAGGCTGCGTGTTCG
GAAATCAACTGACAGGCTTTCGCTTTCCAGAAATAGAAACCGTCTCTGTTCCAAGCTCCCTGCCTTACGACGAATCAAGA
TTTCGCCCCATATAA

Upstream 100 bases:

>100_bases
AGAAAATGATTCTTCTTCTATAATTTGCACATAAAAGCTTGTGATGACTCACAACACTTTGCTTCATAATAAATAAAACA
ATCGGTAAGGAGGAGACCGC

Downstream 100 bases:

>100_bases
AAAAGGAGAGAATCAATGATTCTCTCCTTTTATCAGTTTGCTCATGTCCTGAGGCAGTGGAGCATGAAACCTCATGTTCT
CCTGTGTCAGCGGATGGATA

Product: bis(5'-nucleosyl)-tetraphosphatase PrpE

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAYDIISDIHGCYDEMTALIQKLGYTIKNGVPVHEEGRVLVFAGDLTDRGPKSIEVIRFVAGAYEKGAVRYVPGNHCNKL
YRYLKGNPVKVMHGLETTAAELEELSKDEKKSVSEQFMKLYETAPLYDILHNGELVVAHAGIRADDIGKYTRRVKDFVLY
GDVTGETYPDGRPIRRDWAAAYNGKAWVVYGHTPVKEPRKVNRTINIDTGCVFGNQLTGFRFPEIETVSVPSSLPYDESR
FRPI

Sequences:

>Translated_244_residues
MAYDIISDIHGCYDEMTALIQKLGYTIKNGVPVHEEGRVLVFAGDLTDRGPKSIEVIRFVAGAYEKGAVRYVPGNHCNKL
YRYLKGNPVKVMHGLETTAAELEELSKDEKKSVSEQFMKLYETAPLYDILHNGELVVAHAGIRADDIGKYTRRVKDFVLY
GDVTGETYPDGRPIRRDWAAAYNGKAWVVYGHTPVKEPRKVNRTINIDTGCVFGNQLTGFRFPEIETVSVPSSLPYDESR
FRPI
>Mature_243_residues
AYDIISDIHGCYDEMTALIQKLGYTIKNGVPVHEEGRVLVFAGDLTDRGPKSIEVIRFVAGAYEKGAVRYVPGNHCNKLY
RYLKGNPVKVMHGLETTAAELEELSKDEKKSVSEQFMKLYETAPLYDILHNGELVVAHAGIRADDIGKYTRRVKDFVLYG
DVTGETYPDGRPIRRDWAAAYNGKAWVVYGHTPVKEPRKVNRTINIDTGCVFGNQLTGFRFPEIETVSVPSSLPYDESRF
RPI

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP. Does not hydrolyze Ap2a or Ap6A. Also has an ATPase activity. Was shown to dephosphorylate phosphotyrosine but not phosphoserine or phosphothreonine from phosphorylated peptides. Involved in spore germi

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Forespore

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRPE_BACSU (O31614)

Other databases:

- EMBL:   AL009126
- PIR:   H69844
- RefSeq:   NP_389045.1
- ProteinModelPortal:   O31614
- SMR:   O31614
- PptaseDB:   P3D0410142
- EnsemblBacteria:   EBBACT00000003010
- GeneID:   936412
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU11630
- NMPDR:   fig|224308.1.peg.1164
- GenoList:   BSU11630
- GeneTree:   EBGT00050000002430
- HOGENOM:   HBG724457
- OMA:   HCNKLYR
- PhylomeDB:   O31614
- ProtClustDB:   PRK13625
- BioCyc:   BSUB:BSU11630-MONOMER
- BRENDA:   3.6.1.17
- HAMAP:   MF_01443
- InterPro:   IPR004843

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.17

Molecular weight: Translated: 27464; Mature: 27332

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYDIISDIHGCYDEMTALIQKLGYTIKNGVPVHEEGRVLVFAGDLTDRGPKSIEVIRFV
CCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
AGAYEKGAVRYVPGNHCNKLYRYLKGNPVKVMHGLETTAAELEELSKDEKKSVSEQFMKL
HCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHH
YETAPLYDILHNGELVVAHAGIRADDIGKYTRRVKDFVLYGDVTGETYPDGRPIRRDWAA
HHCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHH
AYNGKAWVVYGHTPVKEPRKVNRTINIDTGCVFGNQLTGFRFPEIETVSVPSSLPYDESR
HCCCCEEEEECCCCCCCHHHCCCEEECCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCC
FRPI
CCCC
>Mature Secondary Structure 
AYDIISDIHGCYDEMTALIQKLGYTIKNGVPVHEEGRVLVFAGDLTDRGPKSIEVIRFV
CHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
AGAYEKGAVRYVPGNHCNKLYRYLKGNPVKVMHGLETTAAELEELSKDEKKSVSEQFMKL
HCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHH
YETAPLYDILHNGELVVAHAGIRADDIGKYTRRVKDFVLYGDVTGETYPDGRPIRRDWAA
HHCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHH
AYNGKAWVVYGHTPVKEPRKVNRTINIDTGCVFGNQLTGFRFPEIETVSVPSSLPYDESR
HCCCCEEEEECCCCCCCHHHCCCEEECCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCC
FRPI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377