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The map label for this gene is yitU

Identifier: 16078178

GI number: 16078178

Start: 1190490

End: 1191302

Strand: Reverse

Name: yitU

Synonym: BSU11140

Alternate gene names: 16078178

Gene position: 1191302-1190490 (Counterclockwise)

Preceding gene: 16078192

Following gene: 255767249

Centisome position: 28.26

GC content: 45.63

Gene sequence:

>813_bases
ATGGAGACAAAACCCTATTTAATCGCATTAGATTTAGATGGAACATTATTAAAGGATGATAAAACCATATCTGAAAACAC
CCTTCATACGATACAGCGCCTAAAAGATGACGGGCATTATGTCTGCATCTCAACAGGCCGTCCGTATCGTTCAAGTTCCA
TGTACTACCAGCAGATGGAGCTGACAACGCCAATTGTCAATTTTAACGGAGCATTTGTCCATCATCCGCAAGACGACAGC
TGGGGACGGTATCATACGTCACTGCCGCTTGATGTTGTCAAACAGCTCGTGGATATCAGCGAGAGCTACAACGTACATAA
CGTGCTTGCTGAAGTGATTGACGACGTATACTTTCATTACCATGATGAGCACCTGATAGATGCCTTTAACATGAACACAA
CAAATGTAACGGTCGGAGACTTGCGGGAAAATCTCGGTGAAGATGTGACGTCCGTACTCATACATGCAAAGGAAGAGGAT
GTGCCGGCAATACGCTCATATTTATCGGATGTGCATGCCGAGGTGATCGACCATAGAAGATGGGCCGCTCCTTGGCATGT
CATTGAAATTATCAAAAGCGGCATGAATAAAGCGGTCGGCCTGCAGAAAATCAGCGATTATTACGGCGTGCCGAGGGAGC
GGATCATTGCTTTTGGAGATGAGGATAACGATTTGGAAATGCTTGAATTTGCAGGCTGCGGCGTTGCAATGGGAAATGGA
ATTGACGCGGTCAAGCAGATTGCCAACCGAACTACGGCCACAAATGAAGAGGACGGCGTGGCAAGGTTTTTGAAAGAATA
TTTCTCACTTTAA

Upstream 100 bases:

>100_bases
AACCATAATCATAAGTGTAACATGTAGACAATAAAGATGGTAAAAAGCTACACTGTAAGTAAGGCAAAACAAGCAAAATC
TAAGGTTAAAGGAGCTTTTC

Downstream 100 bases:

>100_bases
AGAAGGTCCGTATTAATTTTTCCCACTCATAAACCTTACTTTACCCCACCATACTATTGAAGACGACTCATCTCGTCAAA
GTATGGAAGGGGGCAGTCTC

Product: phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
METKPYLIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQMELTTPIVNFNGAFVHHPQDDS
WGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHYHDEHLIDAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEED
VPAIRSYLSDVHAEVIDHRRWAAPWHVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNG
IDAVKQIANRTTATNEEDGVARFLKEYFSL

Sequences:

>Translated_270_residues
METKPYLIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQMELTTPIVNFNGAFVHHPQDDS
WGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHYHDEHLIDAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEED
VPAIRSYLSDVHAEVIDHRRWAAPWHVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNG
IDAVKQIANRTTATNEEDGVARFLKEYFSL
>Mature_270_residues
METKPYLIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQMELTTPIVNFNGAFVHHPQDDS
WGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHYHDEHLIDAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEED
VPAIRSYLSDVHAEVIDHRRWAAPWHVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNG
IDAVKQIANRTTATNEEDGVARFLKEYFSL

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family

Homologues:

Organism=Escherichia coli, GI1786982, Length=280, Percent_Identity=31.0714285714286, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367265, Length=279, Percent_Identity=31.5412186379928, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI87081741, Length=244, Percent_Identity=27.0491803278689, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081790, Length=257, Percent_Identity=24.9027237354086, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YITU_BACSU (P70947)

Other databases:

- EMBL:   Y09476
- EMBL:   Z79580
- EMBL:   AL009126
- PIR:   F69841
- RefSeq:   NP_388995.1
- ProteinModelPortal:   P70947
- SMR:   P70947
- EnsemblBacteria:   EBBACT00000001621
- GeneID:   939795
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU11140
- NMPDR:   fig|224308.1.peg.1114
- GenoList:   BSU11140
- GeneTree:   EBGT00070000031729
- HOGENOM:   HBG728500
- OMA:   YVCISTG
- PhylomeDB:   P70947
- ProtClustDB:   CLSK2752369
- BioCyc:   BSUB:BSU11140-MONOMER
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- Gene3D:   G3DSA:3.40.50.1000
- TIGRFAMs:   TIGR00099
- TIGRFAMs:   TIGR01484

Pfam domain/function: PF08282 Hydrolase_3; SSF56784 SSF56784

EC number: NA

Molecular weight: Translated: 30634; Mature: 30634

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01228 COF_1; PS01229 COF_2

Important sites: ACT_SITE 11-11

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKPYLIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQME
CCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
LTTPIVNFNGAFVHHPQDDSWGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHY
HHCCEEECCCEEEECCCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
HDEHLIDAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEEDVPAIRSYLSDVHAEVIDHRR
CCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
WAAPWHVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHHHCCCCEECCCC
IDAVKQIANRTTATNEEDGVARFLKEYFSL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
METKPYLIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQME
CCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
LTTPIVNFNGAFVHHPQDDSWGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHY
HHCCEEECCCEEEECCCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
HDEHLIDAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEEDVPAIRSYLSDVHAEVIDHRR
CCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
WAAPWHVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHHHCCCCEECCCC
IDAVKQIANRTTATNEEDGVARFLKEYFSL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9025291; 9384377