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The map label for this gene is yhjB

Identifier: 16078109

GI number: 16078109

Start: 1119162

End: 1120631

Strand: Reverse

Name: yhjB

Synonym: BSU10450

Alternate gene names: 16078109

Gene position: 1120631-1119162 (Counterclockwise)

Preceding gene: 16078110

Following gene: 16078107

Centisome position: 26.58

GC content: 49.8

Gene sequence:

>1470_bases
ATGAATGCAGCTCTCATCATCATCTTCGGTGTCCTGCTCTTGAGTATTTTTCTCGGTATACGCGCCCAAAAAGGAAAAGA
CATGAACCTGGAGCAGTGGACGGTCGGAGGGCGCGGCTTCGGAACTGTTTTCGTCTTCCTTTTGATGGCAGGCGAAATTT
ATACTACTTTTACGTTTCTCGGCGGCAGCGGCTGGGCCTACGGAAAAGGCGGTCCAGCCTTTTATATCATCGCCTACGGA
TGTCTGGCCTACATCCTTTCTTACTGGCTTCTTCCAGCAGTTTGGACGTACGCGAAACAGCATAAACTGATGTCGCAGTC
TGATTTTTTCACAAAAAAATACAACAGTCCGCTGCTTGGCATTCTCGTTTCACTGGTCGGCATCGCCGCACTCATTCCCT
ATCTTGTACTGCAGCTGAAAGGCCTCGGGCTGATTGTATCGGAAACCTCGTACGGCAAAATCACCCCGACCGCTGCCATC
TGGATCGGCGCTGTTTCCATCACGGTTTATGTTATGGTTTCAGGCATTCACGGGTCTGCCTGGATATCGGTTGTGAAGGA
CATCATGATTCTGGTTGTCGTTCTGTTTTTAGGTGTGTATTTGCCAATTCATTACTACGGCGGATTTCAAGACATGTTTC
AGCAGATTGAAACGGCAAAGCCTGGCTTTCTTACGCTCCCCGAATCGGGACAAAGTGTGGCCTGGTTCAGTTCAACCGTA
CTCTTGACAGCGCTTGGTTTTTACATGTGGCCTCACACGTTTTCCGCTTCGTATTCAGCCGAAAACCCAAAAGTGTTTCG
TAAAAACGCCATCATCATGCCTTTGTACCAGCTGGTCCTGCTCTTCGTCCTTTTCGTCGGCTTTGCGGCTATCCTGCAAG
TTCCAGATCTGAATGGCGCAGACGGGGATTTGTCGCTTTTGAGACTGTCTCTGCAAGCATTTGACCCTTGGTTTGTCGGA
ATTATCGGTGCTGCCGGACTGCTGACAGCACTTGTGCCAGGGTCTATGATCTTAATGTCCGCCTCCACACTGTTTGCAAA
AAATGTGTACAAGGTAATCGCGCCCCGCACGACAGAACAGCAAGTATCGGCGCTTGCTAAGTTTTTAGTGCCGGTGATTG
CGCTGATTTCGGTGTATTTTACCTTCAAAGGCGGGAATACCATCGTTACGCTGCTTTTGATGGGCTACAGCCTTGTCACA
CAGCTATTCCCCGCCCTTTTGTTCAGCCTGCTCAAGCATAATATGGTGACAAAGCAAGGAGCTTTCGCCGGCATTATTGC
AGGTGTCGGAGCAGTTACTTATATTACAATGACGGAAACGACGATCGGCACTTTATTTCCGGCTCTGCCGCAAGCCGCAA
AAGACTTGAATGTCGGCATCGTCGCCCTGCTTTTGAATATCACGGTCATGATGGCAGTCAGCCTTATGACAAGGAAGGCG
AAAAGCGCTGCGGCCGATCAGGCGGCCTAA

Upstream 100 bases:

>100_bases
CGTTTATTCTTGCCTATATTGTGATGTGGGCTCTTTTGACCTCTGCGCTGATGGCGATTGTGTATGTCCTCGACAAGGAA
AATAAAAAGGAGGAAGCAGA

Downstream 100 bases:

>100_bases
GCATAAAAAAAGCAATCTGGACACCAGATTGCTTTTTCTTATTTACCGTTCACAGGCGATAAGATCTTTATCGCGGTCTT
TGTTTTTATTGGCATCGTAA

Product: Na+/metabolite cotransporter

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYGKGGPAFYIIAYG
CLAYILSYWLLPAVWTYAKQHKLMSQSDFFTKKYNSPLLGILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAI
WIGAVSITVYVMVSGIHGSAWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSSTV
LLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLYQLVLLFVLFVGFAAILQVPDLNGADGDLSLLRLSLQAFDPWFVG
IIGAAGLLTALVPGSMILMSASTLFAKNVYKVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVT
QLFPALLFSLLKHNMVTKQGAFAGIIAGVGAVTYITMTETTIGTLFPALPQAAKDLNVGIVALLLNITVMMAVSLMTRKA
KSAAADQAA

Sequences:

>Translated_489_residues
MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYGKGGPAFYIIAYG
CLAYILSYWLLPAVWTYAKQHKLMSQSDFFTKKYNSPLLGILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAI
WIGAVSITVYVMVSGIHGSAWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSSTV
LLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLYQLVLLFVLFVGFAAILQVPDLNGADGDLSLLRLSLQAFDPWFVG
IIGAAGLLTALVPGSMILMSASTLFAKNVYKVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVT
QLFPALLFSLLKHNMVTKQGAFAGIIAGVGAVTYITMTETTIGTLFPALPQAAKDLNVGIVALLLNITVMMAVSLMTRKA
KSAAADQAA
>Mature_489_residues
MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYGKGGPAFYIIAYG
CLAYILSYWLLPAVWTYAKQHKLMSQSDFFTKKYNSPLLGILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAI
WIGAVSITVYVMVSGIHGSAWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSSTV
LLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLYQLVLLFVLFVGFAAILQVPDLNGADGDLSLLRLSLQAFDPWFVG
IIGAAGLLTALVPGSMILMSASTLFAKNVYKVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVT
QLFPALLFSLLKHNMVTKQGAFAGIIAGVGAVTYITMTETTIGTLFPALPQAAKDLNVGIVALLLNITVMMAVSLMTRKA
KSAAADQAA

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family

Homologues:

Organism=Escherichia coli, GI87082237, Length=376, Percent_Identity=24.468085106383, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHJB_BACSU (O07556)

Other databases:

- EMBL:   Y14081
- EMBL:   AL009126
- PIR:   B69833
- RefSeq:   NP_388926.1
- ProteinModelPortal:   O07556
- EnsemblBacteria:   EBBACT00000003084
- GeneID:   939317
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10450
- NMPDR:   fig|224308.1.peg.1045
- GenoList:   BSU10450
- GeneTree:   EBGT00070000031986
- HOGENOM:   HBG670534
- OMA:   SDRQVAK
- ProtClustDB:   CLSK887013
- BioCyc:   BSUB:BSU10450-MONOMER
- InterPro:   IPR001734
- PANTHER:   PTHR11819

Pfam domain/function: PF00474 SSF

EC number: NA

Molecular weight: Translated: 52763; Mature: 52763

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd95979c)-; HASH(0xdf4ab70)-; HASH(0xe3a745c)-; HASH(0xbd43588)-; HASH(0xdec282c)-; HASH(0xde66708)-; HASH(0xd9310b4)-; HASH(0xe26d01c)-; HASH(0xd722404)-; HASH(0xe5bf240)-; HASH(0xdcaec24)-; HASH(0xdb08198)-; HASH(0xdc3010c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCHHHHHHEEE
GGSGWAYGKGGPAFYIIAYGCLAYILSYWLLPAVWTYAKQHKLMSQSDFFTKKYNSPLLG
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
ILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAIWIGAVSITVYVMVSGIHGSA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEECCCHHH
WISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSSTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCEEHHHHHHH
LLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLYQLVLLFVLFVGFAAILQVPDLNGA
HHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DGDLSLLRLSLQAFDPWFVGIIGAAGLLTALVPGSMILMSASTLFAKNVYKVIAPRTTEQ
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
QVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVTQLFPALLFSLLKHNMVTKQG
HHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFAGIIAGVGAVTYITMTETTIGTLFPALPQAAKDLNVGIVALLLNITVMMAVSLMTRKA
HHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KSAAADQAA
HHHCCCCCH
>Mature Secondary Structure
MNAALIIIFGVLLLSIFLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCHHHHHHEEE
GGSGWAYGKGGPAFYIIAYGCLAYILSYWLLPAVWTYAKQHKLMSQSDFFTKKYNSPLLG
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
ILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAIWIGAVSITVYVMVSGIHGSA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEECCCHHH
WISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSSTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCEEHHHHHHH
LLTALGFYMWPHTFSASYSAENPKVFRKNAIIMPLYQLVLLFVLFVGFAAILQVPDLNGA
HHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DGDLSLLRLSLQAFDPWFVGIIGAAGLLTALVPGSMILMSASTLFAKNVYKVIAPRTTEQ
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
QVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVTQLFPALLFSLLKHNMVTKQG
HHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFAGIIAGVGAVTYITMTETTIGTLFPALPQAAKDLNVGIVALLLNITVMMAVSLMTRKA
HHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KSAAADQAA
HHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377