BacMap

Definition	Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
Accession	NC_000964
Length	4,215,606

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The map label for this gene is yhxD

Identifier: 16078107

GI number: 16078107

Start: 1117734

End: 1118633

Strand: Reverse

Name: yhxD

Synonym: BSU10430

Alternate gene names: 16078107

Gene position: 1118633-1117734 (Counterclockwise)

Preceding gene: 16078109

Following gene: 16078105

Centisome position: 26.54

GC content: 48.78

Gene sequence:

>900_bases
ATGTCTGATTCAAATCTTACGAATCCTATAAAAGCATTTTTTCATGATGAATTTCCCGAACAATATCAAGAACCGCCAGG
CCTGCAAAAGAACATGAAGCCTGTCCCTGATTGCGGAGAAAAAAGCTACAAAGGATCAGGTAAACTAACGGGTCGAAAAG
CGCTTGTCACGGGCGGCGATTCCGGTATCGGCCGCGCTGCCGCAATTGCTTACGCCAGAGAAGGTGCCGATGTGGCTATT
AACTACTTGCCCGAGGAACAGCCAGATGCTGAAGAGGTAAAAGAGCTGATTGAAGCAGAAGGCCGAAAAGCAGTGCTGAT
CCCCGGAGACTTGAGCGACGAATCCTTTTGCCAAGATCTAGTCAAACAGTCGCATCACGAACTCGGCGGACTTGATGTGC
TAGCGCTCGTTGCAGGCAAACAGCAAGCGGTCGAAAACATCGAAGATCTGCCTACTGAACAAATCTATAAAACATTTGAA
GTGAACGTCTTTTCCCTTTACTGGGTTGTAAAAGCGGCGCTTCCGTATTTGCCGGAGGGAGCTTCAATTATCACAACTAC
CTCAGTTGAAGGCTATAATCCAAGCCCGATGCTGTTAGATTACGCAGCAACGAAAAACGCCATTATCGGCTTTACCGTCG
GACTGGGAAAACAGCTTGCTTCCAAAGGCATCAGAGTAAATTCAGTTGCGCCCGGACCAATTTGGACACCGCTGCAAATT
TCCGGCGGACAGCCGACGGAAAACATCCCGAAATTCGGACAAGGCACGCCGCCAGCTCCATTAAATCGCGCTGGGCAGCC
AGTGGAATTGGCCGATGTTTATGTATTTCTAGCTTCAGAGAATTCAAGCTATGTGACATCTCAGGTATATGGCATCACCG
GAGGAATTCCGACGGCATAG

Upstream 100 bases:

>100_bases
TTCTTTTTCCTTCACTATTCAAACTGCCAAAACATGTTTTTCTGCTTATGCTCAGGGGTACACATACGAATGTACACCAA
ACAGAAAAGGAGCGTTGCTG

Downstream 100 bases:

>100_bases
CTTTATGAAAGGAGCTGCCCTGTTCGGTCAGCTCCTTCCTATTTTTCTAATACCGTTCCCCGAGCTCACGCAAAATAAAA
TCATAAATCATCTTCGTCCG

Product: oxidoreductase

Products: NA

Alternate protein names: ORFY

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYKGSGKLTGRKALVTGGDSGIGRAAAIAYAREGADVAI
NYLPEEQPDAEEVKELIEAEGRKAVLIPGDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFE
VNVFSLYWVVKAALPYLPEGASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVNSVAPGPIWTPLQI
SGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTSQVYGITGGIPTA

Sequences:

>Translated_299_residues
MSDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYKGSGKLTGRKALVTGGDSGIGRAAAIAYAREGADVAI
NYLPEEQPDAEEVKELIEAEGRKAVLIPGDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFE
VNVFSLYWVVKAALPYLPEGASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVNSVAPGPIWTPLQI
SGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTSQVYGITGGIPTA
>Mature_298_residues
SDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYKGSGKLTGRKALVTGGDSGIGRAAAIAYAREGADVAIN
YLPEEQPDAEEVKELIEAEGRKAVLIPGDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEV
NVFSLYWVVKAALPYLPEGASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVNSVAPGPIWTPLQIS
GGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTSQVYGITGGIPTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=29.0196078431373, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=32.4110671936759, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=32.0610687022901, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI59889578, Length=202, Percent_Identity=31.6831683168317, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=35.4166666666667, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=26.5151515151515, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=28.8065843621399, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI32455239, Length=180, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031765, Length=180, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=27.1317829457364, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=31, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=26.4367816091954, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=200, Percent_Identity=29, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=31.25, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=27.4436090225564, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=28.3505154639175, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=28.7958115183246, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=27.9569892473118, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789378, Length=292, Percent_Identity=64.3835616438356, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=36.2549800796813, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=30.1960784313725, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=30.8, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=31.0483870967742, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=30.5555555555556, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.7937743190661, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=28.0632411067194, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=27.4900398406374, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=33.0798479087452, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=33.0798479087452, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=30.1587301587302, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.1740890688259, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=29.9242424242424, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=29.4354838709677, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=28.2868525896414, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=30.9803921568627, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=32.5581395348837, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=232, Percent_Identity=31.8965517241379, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=32.046332046332, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.3893129770992, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.6577946768061, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=245, Percent_Identity=28.1632653061224, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=29.2592592592593, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.8625954198473, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=29.277566539924, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=30.8823529411765, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=25.8555133079848, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=209, Percent_Identity=31.1004784688995, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=225, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=26.2172284644195, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=28.4644194756554, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=26.7716535433071, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=29.2134831460674, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=27.7227722772277, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=261, Percent_Identity=25.2873563218391, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=32.2834645669291, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=31.8897637795276, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=32.9218106995885, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571526, Length=243, Percent_Identity=32.9218106995885, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=29.7619047619048, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=31.25, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=28.936170212766, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.9236947791165, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=115, Percent_Identity=38.2608695652174, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=27.5510204081633, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHXD_BACSU (P40398)

Other databases:

- EMBL:   Y14081
- EMBL:   Y14084
- EMBL:   AL009126
- EMBL:   S70734
- PIR:   E69835
- RefSeq:   NP_388924.1
- ProteinModelPortal:   P40398
- SMR:   P40398
- EnsemblBacteria:   EBBACT00000002482
- GeneID:   939776
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10430
- NMPDR:   fig|224308.1.peg.1043
- GenoList:   BSU10430
- GeneTree:   EBGT00070000031724
- HOGENOM:   HBG750976
- OMA:   VTAQIYG
- PhylomeDB:   P40398
- ProtClustDB:   CLSK887011
- BioCyc:   BSUB:BSU10430-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31909; Mature: 31778

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 201-201 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYKGSGKLTGRKALVTGGD
CCCCCCCHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
SGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLIPGDLSDESFCQDL
CCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
VKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLYWVVKAALPYLPEG
HHHHHHHCCCCEEEEHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVNSVAPGPIWTPLQI
CEEEEEEECCCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHCCCEEECCCCCCCCCCEEE
SGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTSQVYGITGGIPTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
SDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYKGSGKLTGRKALVTGGD
CCCCCCHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
SGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLIPGDLSDESFCQDL
CCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
VKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLYWVVKAALPYLPEG
HHHHHHHCCCCEEEEHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVNSVAPGPIWTPLQI
CEEEEEEECCCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHCCCEEECCCCCCCCCCEEE
SGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTSQVYGITGGIPTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8196543