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The map label for this gene is comK

Identifier: 16078106

GI number: 16078106

Start: 1117109

End: 1117687

Strand: Direct

Name: comK

Synonym: BSU10420

Alternate gene names: 16078106

Gene position: 1117109-1117687 (Clockwise)

Preceding gene: 16078104

Following gene: 16078108

Centisome position: 26.5

GC content: 44.04

Gene sequence:

>579_bases
ATGAGTCAGAAAACAGACGCACCTTTAGAATCGTATGAAGTGAACGGCGCAACAATTGCCGTGCTGCCAGAAGAAATAGA
CGGCAAAATCTGTTCCAAAATTATTGAAAAAGATTGCGTGTTTTATGTAAACATGAAGCCGCTGCAAATTGTCGACAGAA
GCTGCCGATTTTTTGGATCAAGCTATGCGGGAAGAAAAGCAGGAACTTATGAAGTGACAAAAATTTCACACAAGCCGCCG
ATCATGGTGGACCCTTCGAACCAAATCTTTTTATTCCCTACACTTTCTTCGACAAGACCCCAATGCGGCTGGATTTCCCA
TGTGCATGTAAAAGAATTCAAAGCGACTGAATTCGACGATACGGAAGTGACGTTTTCCAATGGGAAAACGATGGAGCTGC
CGATCTCTTATAATTCGTTCGAGAACCAGGTATACCGAACAGCGTGGCTCAGAACCAAATTCCAAGACAGAATCGACCAC
CGCGTGCCGAAAAGACAGGAATTTATGCTGTACCCGAAAGAAGAGCGGACGAAGATGATTTATGATTTTATTTTGCGTGA
GCTCGGGGAACGGTATTAG

Upstream 100 bases:

>100_bases
AGATGATTTTATCTTAAATGTTAAAAAAACCTGTCGTTTTACAAAAACAGATGATAGATTATTAGTATAAATTTTGCAGA
AAAAGGATGGAGGCCATAAT

Downstream 100 bases:

>100_bases
AAAAATAGGAAGGAGCTGACCGAACAGGGCAGCTCCTTTCATAAAGCTATGCCGTCGGAATTCCTCCGGTGATGCCATAT
ACCTGAGATGTCACATAGCT

Product: competence transcription factor (CTF)

Products: NA

Alternate protein names: CTF; Competence protein K

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGSSYAGRKAGTYEVTKISHKPP
IMVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDDTEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDH
RVPKRQEFMLYPKEERTKMIYDFILRELGERY

Sequences:

>Translated_192_residues
MSQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGSSYAGRKAGTYEVTKISHKPP
IMVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDDTEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDH
RVPKRQEFMLYPKEERTKMIYDFILRELGERY
>Mature_191_residues
SQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGSSYAGRKAGTYEVTKISHKPPI
MVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDDTEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDHR
VPKRQEFMLYPKEERTKMIYDFILRELGERY

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COMK_BACSU (P40396)

Other databases:

- EMBL:   S70734
- EMBL:   Y14084
- EMBL:   AL009126
- PIR:   S43611
- RefSeq:   NP_388923.1
- ProteinModelPortal:   P40396
- MINT:   MINT-2838890
- EnsemblBacteria:   EBBACT00000002148
- GeneID:   936338
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10420
- NMPDR:   fig|224308.1.peg.1042
- GenoList:   BSU10420
- GeneTree:   EBGT00050000001522
- HOGENOM:   HBG532928
- OMA:   GITHKAP
- ProtClustDB:   CLSK887010
- BioCyc:   BSUB:BSU10420-MONOMER
- GO:   GO:0006350
- InterPro:   IPR010461
- PIRSF:   PIRSF011560

Pfam domain/function: PF06338 ComK

EC number: NA

Molecular weight: Translated: 22430; Mature: 22299

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGS
CCCCCCCCCHHEECCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCC
SYAGRKAGTYEVTKISHKPPIMVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDD
CCCCCCCCCEEEEEECCCCCEEECCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCC
TEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDHRVPKRQEFMLYPKEERTKMI
CEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
YDFILRELGERY
HHHHHHHHHCCC
>Mature Secondary Structure 
SQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGS
CCCCCCCCHHEECCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCC
SYAGRKAGTYEVTKISHKPPIMVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDD
CCCCCCCCCEEEEEECCCCCEEECCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCC
TEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDHRVPKRQEFMLYPKEERTKMI
CEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
YDFILRELGERY
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713