Click here to switch to the map view.

The map label for this gene is yhdH

Identifier: 16078012

GI number: 16078012

Start: 1024865

End: 1026220

Strand: Direct

Name: yhdH

Synonym: BSU09470

Alternate gene names: 16078012

Gene position: 1024865-1026220 (Clockwise)

Preceding gene: 16078011

Following gene: 16078014

Centisome position: 24.31

GC content: 45.06

Gene sequence:

>1356_bases
TTGTCTGAGCAAAAACCAGTCCAATGGGCTTCGAAAATTGGTTTCGTCATGGCAGCGGCCGGCTCGGCTATCGGCTTGGG
CGCGATTTGGAAGTTCCCTTACGTAGCGGGGACCAATGGGGGAGGAGCCTTTTTTCTTATCTTCGTGTTATTTACCATCC
TCTTAGGCTATCCGCTTTTGGTGGGGGAATTTATTTTTGGAAGACGGAACCAGACGAATGCCATTGATGCATATAAAAAA
GAAGCGCCGCGATCAGCTTGGTTTCTTACGGGGTGGATCGGCGTAGCGGCGTGTTTCTTAGTGCTGTCGTTTTACAGTGT
AATCGGGGGATGGATTTTGCTGTATATCGTGAAAACAGCGTCAGGATCACTGTCCGGGCTTTCTCAAGCACAGTATGGCG
CTCTTTTTGCTTCTATTATCCAAAATCCGGTGCAGACGCTCGCGGCTCAGCTTGTCTTTATGGCACTGACTGTACTCGTT
GTCGCAAGAGGGGTTCAAAAAGGGATTGAACGGGTAAGCGCGGTGATGATGCCGATTTTGTTTTTATTGTTTATTCTGCT
CGTTCTTCGGTCTCTTACGCTTAATGGTGCAATGGAAGGCGTAAAGTTTCTGCTTGTGCCTCATTTCGGCGATCTGACTC
CGGAATCCATATTATTCGCGCTGGGACAGGCCTTCTTTACGTTAACACTGGGGGTTTCGGTGATGGTGACCTACAGCTCC
TATTTGCCGAAAACACAAAATATCCCTCGTTCGGCAGCCTCCATTGTCTTGATGAATATCATTGTGACACTCTTGGCAGG
TTTGGCTATTTTTCCGGCGGTTTTCTCATTCGGTTTTCAGCCAAATGAAGGACCGACATTGCTGTTTACAGTGCTTCCGG
CCGTTTTTGAACAGCTTCCGTTCGGCACATTGTTTTTTATCGGCTTTCTCGTTGCATTTTTATTTGCAGCCTTAACCTCA
GCATTTTCGATGGTTGAAATTATCGTTGCCACAATCGGAAAAGGGGACGAAAAGAAGAGAAAAAAACTGTCATGGACGAG
CGGGCTTTTGATCTTTTTGGTCGGAATCCCATGCTGCTTGTCTTATGGCGTTTTGAGTGATGTGCACCTATTTGGCAAAA
CGTTTTTTGATATTGCCGATTTTACCGTCAGCAATGTTTTGATGCCTTCAGGCGCTCTGTTAATTTCTCTATTTATCCCG
CTGAAAATTTCGAAAAGCGAACTCTTGGCTGAAATGCGAAATGGATCAAATGCAGGTAAAGCATTCTTTTACACATGGTT
TTATTTGCTTCGTTTTATCGTGCCGCTTGCCATTATTATCGTGTTCTTAAATTTAATCGGAATTTTATCATTTTAA

Upstream 100 bases:

>100_bases
CGGCCATACAGGCCGCCTCTTTTCTGTTCTTGGCAAATGAATCTATAGAAATGAAGACAAAAATAAGAGATAATATAGGC
TGGAAAGGAAGTGACGTTTA

Downstream 100 bases:

>100_bases
AAAACAGGCTCCGTTTCCGGGGCCTGTTTTTTATTTAATAAGATGATATCAACGGTGCCCATGCCGTTTTCAGTTTTTGG
ATGCCGAGCCTGATGTCCTC

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSEQKPVQWASKIGFVMAAAGSAIGLGAIWKFPYVAGTNGGGAFFLIFVLFTILLGYPLLVGEFIFGRRNQTNAIDAYKK
EAPRSAWFLTGWIGVAACFLVLSFYSVIGGWILLYIVKTASGSLSGLSQAQYGALFASIIQNPVQTLAAQLVFMALTVLV
VARGVQKGIERVSAVMMPILFLLFILLVLRSLTLNGAMEGVKFLLVPHFGDLTPESILFALGQAFFTLTLGVSVMVTYSS
YLPKTQNIPRSAASIVLMNIIVTLLAGLAIFPAVFSFGFQPNEGPTLLFTVLPAVFEQLPFGTLFFIGFLVAFLFAALTS
AFSMVEIIVATIGKGDEKKRKKLSWTSGLLIFLVGIPCCLSYGVLSDVHLFGKTFFDIADFTVSNVLMPSGALLISLFIP
LKISKSELLAEMRNGSNAGKAFFYTWFYLLRFIVPLAIIIVFLNLIGILSF

Sequences:

>Translated_451_residues
MSEQKPVQWASKIGFVMAAAGSAIGLGAIWKFPYVAGTNGGGAFFLIFVLFTILLGYPLLVGEFIFGRRNQTNAIDAYKK
EAPRSAWFLTGWIGVAACFLVLSFYSVIGGWILLYIVKTASGSLSGLSQAQYGALFASIIQNPVQTLAAQLVFMALTVLV
VARGVQKGIERVSAVMMPILFLLFILLVLRSLTLNGAMEGVKFLLVPHFGDLTPESILFALGQAFFTLTLGVSVMVTYSS
YLPKTQNIPRSAASIVLMNIIVTLLAGLAIFPAVFSFGFQPNEGPTLLFTVLPAVFEQLPFGTLFFIGFLVAFLFAALTS
AFSMVEIIVATIGKGDEKKRKKLSWTSGLLIFLVGIPCCLSYGVLSDVHLFGKTFFDIADFTVSNVLMPSGALLISLFIP
LKISKSELLAEMRNGSNAGKAFFYTWFYLLRFIVPLAIIIVFLNLIGILSF
>Mature_450_residues
SEQKPVQWASKIGFVMAAAGSAIGLGAIWKFPYVAGTNGGGAFFLIFVLFTILLGYPLLVGEFIFGRRNQTNAIDAYKKE
APRSAWFLTGWIGVAACFLVLSFYSVIGGWILLYIVKTASGSLSGLSQAQYGALFASIIQNPVQTLAAQLVFMALTVLVV
ARGVQKGIERVSAVMMPILFLLFILLVLRSLTLNGAMEGVKFLLVPHFGDLTPESILFALGQAFFTLTLGVSVMVTYSSY
LPKTQNIPRSAASIVLMNIIVTLLAGLAIFPAVFSFGFQPNEGPTLLFTVLPAVFEQLPFGTLFFIGFLVAFLFAALTSA
FSMVEIIVATIGKGDEKKRKKLSWTSGLLIFLVGIPCCLSYGVLSDVHLFGKTFFDIADFTVSNVLMPSGALLISLFIPL
KISKSELLAEMRNGSNAGKAFFYTWFYLLRFIVPLAIIIVFLNLIGILSF

Specific function: Putative sodium-dependent transporter

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Homologues:

Organism=Homo sapiens, GI21361581, Length=388, Percent_Identity=26.2886597938144, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI188528618, Length=424, Percent_Identity=25.2358490566038, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI4507043, Length=396, Percent_Identity=24.4949494949495, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI58219014, Length=315, Percent_Identity=28.2539682539683, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI33354281, Length=316, Percent_Identity=25.9493670886076, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI194018524, Length=303, Percent_Identity=26.4026402640264, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI7657587, Length=382, Percent_Identity=24.3455497382199, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507041, Length=390, Percent_Identity=25.8974358974359, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI51468073, Length=297, Percent_Identity=25.2525252525253, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI11181770, Length=300, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI171184408, Length=405, Percent_Identity=25.1851851851852, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184406, Length=405, Percent_Identity=25.1851851851852, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184404, Length=405, Percent_Identity=25.1851851851852, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI134304856, Length=384, Percent_Identity=25.78125, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI289191351, Length=403, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557046, Length=403, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI289191377, Length=403, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI197276623, Length=381, Percent_Identity=25.4593175853018, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI54607094, Length=381, Percent_Identity=25.4593175853018, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI12408638, Length=277, Percent_Identity=24.187725631769, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI21361693, Length=122, Percent_Identity=32.7868852459016, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI5032097, Length=355, Percent_Identity=23.3802816901408, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI197276625, Length=129, Percent_Identity=34.8837209302326, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=468, Percent_Identity=24.1452991452991, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17555248, Length=426, Percent_Identity=25.3521126760563, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25146584, Length=419, Percent_Identity=24.8210023866348, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71995588, Length=394, Percent_Identity=22.0812182741117, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI133952791, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17542050, Length=133, Percent_Identity=33.8345864661654, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71998244, Length=337, Percent_Identity=23.4421364985163, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569475, Length=417, Percent_Identity=23.2613908872902, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136952, Length=407, Percent_Identity=24.5700245700246, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281364394, Length=404, Percent_Identity=24.7524752475248, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574704, Length=404, Percent_Identity=24.7524752475248, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136950, Length=404, Percent_Identity=24.7524752475248, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574702, Length=404, Percent_Identity=24.7524752475248, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45550877, Length=457, Percent_Identity=26.2582056892779, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45551183, Length=438, Percent_Identity=26.027397260274, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24762620, Length=387, Percent_Identity=25.8397932816537, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24639514, Length=507, Percent_Identity=24.4575936883629, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI221329674, Length=507, Percent_Identity=24.4575936883629, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24639516, Length=299, Percent_Identity=27.7591973244147, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281364136, Length=401, Percent_Identity=24.1895261845387, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19921936, Length=386, Percent_Identity=24.8704663212435, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24652942, Length=432, Percent_Identity=25.6944444444444, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45551088, Length=432, Percent_Identity=25.6944444444444, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655079, Length=299, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24661428, Length=383, Percent_Identity=24.8041775456919, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24582567, Length=375, Percent_Identity=25.8666666666667, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24654186, Length=239, Percent_Identity=30.1255230125523, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHDH_BACSU (O07577)

Other databases:

- EMBL:   Y14082
- EMBL:   AL009126
- PIR:   F69825
- RefSeq:   NP_388828.1
- HSSP:   O67854
- ProteinModelPortal:   O07577
- SMR:   O07577
- EnsemblBacteria:   EBBACT00000001982
- GeneID:   936264
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09470
- NMPDR:   fig|224308.1.peg.947
- GenoList:   BSU09470
- GeneTree:   EBGT00070000032073
- HOGENOM:   HBG702834
- OMA:   QGFANAF
- ProtClustDB:   CLSK886961
- BioCyc:   BSUB:BSU09470-MONOMER
- InterPro:   IPR000175
- PANTHER:   PTHR11616
- PRINTS:   PR00176

Pfam domain/function: PF00209 SNF

EC number: NA

Molecular weight: Translated: 48942; Mature: 48811

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1; PS00754 NA_NEUROTRAN_SYMP_2; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdc24034)-; HASH(0xb6bc550)-; HASH(0xc90fc9c)-; HASH(0xe058cf0)-; HASH(0xc415d5c)-; HASH(0xd7b1d3c)-; HASH(0xdaf68d0)-; HASH(0xdfdacf4)-; HASH(0xdfadccc)-; HASH(0xde5d7f0)-; HASH(0xcbe340c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SEQKPVQWASKIGFVMAAAGSAIGLGAIWKFPYVAGTNGGGAFFLIFVLFTILLGYPLL
CCCCHHHHHHHHHHHHHHCCCHHCHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377