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The map label for this gene is yhcR

Identifier: 16077984

GI number: 16077984

Start: 991348

End: 995001

Strand: Direct

Name: yhcR

Synonym: BSU09190

Alternate gene names: 16077984

Gene position: 991348-995001 (Clockwise)

Preceding gene: 255767212

Following gene: 16077985

Centisome position: 23.52

GC content: 45.43

Gene sequence:

>3654_bases
ATGCTGTCTGTCGAAATGATAAGCAGACAAAATCGTTGTCATTATGTGTATAAGGGAGGAAATATGATGAGGCGTATTCT
GCATATTGTGTTGATCACGGCATTAATGTTCTTAAATGTAATGTACACGTTCGAAGCTGTAAAGGCAGCTGAACCGCAAC
AGCCTATATCGATTGAGAAGGCAATACAGCAAAAAGAAGGACAGGCACTTGTCGAAGGATATGCAGTCGGCCAGGCTGTT
TCCCCGCAGCATTATAAACTGACAAGCCCTTTTTCAAATGATTATAATGTTGCGCTGGCAGACCGTAAAAACAAAACATC
GCCCGAACACATCCTTCCTGTGCAAATCCCCTCCGCCTTCAGAAGCCAATTTGGGCTGCAAACCAATCCGCTTCTTCTTG
GGAAAAAGATAACGGTTCAAGGAAAGCTTGAAAATTACTTTAACACGACAGGACTTAAAAACGTTCAGTCGATGAACGTA
ACCGATGACACAAAAACTCCGCCGGCTGAACAGCAAGTGACCATAAATGAAGCACGGGGAAGGCTGAATGAAGAAGTAAC
GATAAAAGGGATCATTACAGCTGATCAAAACGCAATCGGAGGCGGGAAGCTGTCGACCTTTTTGCAAGATGAAACCGGAG
GCATTAACATTTATTCGCCATCCCCTGAACAATTTCCCGAATTAAAAGAGGGTATGGATGTCACGGTGACAGGGAAAATC
ACGTCTTACCAGGGGCTGAAAGAAATCGTTCCAAACTCATCAGGCATCAAAATCAACCAGTCAAATCAATCCCTCCCCGC
CCCCAAACACTTAACAATCAATGAACTTATTAACGGCAGCCTAGGTGATCAGTATGAAGGACGCCTTGTGAAACTAACCG
CTTTTGTTTCCTCAATTCCAAGTTCTCCTGCCGGCGGCGGTTACAATGTAACAATGATTGATGACGACCATCATGCAATG
ACGCTCCGGGTTATGAATGAAACAGGGGTGATAAACGAGCTTGATGAGGGCAAATGGTATGAATTTACCGGTGTGTTAAG
CAGATACCAAACCTTTCAGCTGCTTCCGCGAAAATCGGCTGACCTGAAGCTGCTTGAAGAGCAGCCCGCACCTCCGTCTG
CAGAGGGAGAATATGAAGGGATTGTTGACCGGGTAGTTGACGGCGATACCATTCATCTTAAATCTCCGGTGCTTGGAACG
ACAAAAATCCGGTTTGTAAATGTAGATGCACCCGAAACATATCACACACCAAAAAATGACGCAGATGAAAATCAATTAAG
ATTTGGCAAAAAAGCATCTGACTATCTAAAAACGGTTCTGTCCCCGGGTGATAAAATTACTGTCAAGGTCGGGAGTGAAG
CCAAGGACAGCTATGGCAGATTGCTCGGACAAGTCATAACCGAATCAGGTTCAAACGTGAACTTAGAGCTTGTAAAAAAC
GGCTATGCTCCGACGTATTTTATTTGGCCGGTTGACAATGAAGAGGATTATCAGCAATTTCAGGCCGCAGTAGCCGCTGC
AAAAAAAGATCAAAAAGGAATTTGGAATGAAAACGATCCCCTCATGGAAATGCCGTTTGAATTCAGAGCCAGAGAGCAAG
GGAAAGGCCTGACAAGATATGTGGGGGACTCGTCGAATAAAACATATGTGCAGCCAGCTGACTGGAAGAAGATAGCTGTG
GAAAACAGAATTTTCTTCGCCTCAGCAAGTGAAGCGGAGAGCGCGGGATATAAAAAAAGGCAAACGGCACCTCAAGAACA
TGTGCCGCTTAGAATTCTCAGCATGAATGATTTGCATGGCAAAATCGATCAGCAATATGAGCTTGATCTTGATGGAAATG
GAACTGTAGACGGCACGTTTGGACGCATGGATTATGCCGCCGCATATTTAAAAGAAAAAAAGGCTGAAAAGAAAAACTCG
CTGATTGTGCACGCGGGAGATATGATCGGCGGAAGCTCTCCAGTTTCCTCTCTTCTTCAGGATGAACCGACTGTAGAACT
GATGGAGGACATCGGATTTGATGTCGGAACCGTGGGAAACCACGAATTTGATGAAGGCACGGATGAACTTCTGAGGATCT
TAAATGGCGGTGATCATCCGAAAGGCACAAGCGGATATGATGGACAGAACTTTCCCCTTGTATGTGCCAATTGTAAAATG
AAATCAACTGGAGAGCCCTTTTTGCCGGCTTACGACATCATTAATGTGGAGGGCGTACCCGTTGCTTTTATCGGAGTTGT
CACACAGTCGGCAGCTGGCATGGTTATGCCTGAAGGAATAAAAAATATCGAGTTTACAGATGAAGCAACAGCGGTGAATA
AGGCGGCCGAAGAGCTCAAGAAAAAAGGCGTGAAGGCCATCGCGGTTCTCGCACATATGTCAGCTGAACAAAACGGCAAC
GCCATTACCGGTGAGTCTGCTGATCTTGCAAACAAAACAGATTCTGAAATTGACGTGATTTTTGCCGCGCATAATCATCA
GGTTGTTAACGGTGAAGTGAATGGAAAACTGATTGTTCAAGCGTTTGAATATGGAAAAGCGATAGGTGTCGTTGATGTAG
AGATCGATAAAACGACAAAAGACATTGTCAAAAAGTCCGCGGAAATCGTATATGTTGATCAAAGTAAAATCGAACCGGAT
GTCAGCGCGTCAGCCATTTTAAAGAAATACGAAACAATTGCGGAACCGATTATCAGCGAGGTAGTCGGCGAAGCCGCTGT
TGATATGGAAGGGGGGTATTCAAATGACGGCGATACACCTCTTGGAAACCTGATTGCGGATGGTATGAGAGCTGCCATGA
AAACGGATTTTGCCCTTATGAATGGCGGCGGCATACGTGAAGCGCTGAAGAAGGGTCCAATTACGTGGGGAGATCTTTAC
AATATTCAGCCGTTTGGAAATGTGTTAACGAAGCTTGAGATTAAAGGAAAAGATTTAAGAGAGATTATCAATGCGCAAAT
CTCGCCGGTTTTTGGGCCTGACTACAGCATCAGCGGGTTTACGTATACGTGGGATAAAGAAACCGGAAAAGCAGTTGATA
TGAAAATGGCAGATGGCACCGAGATCCAGCCCGATGCCACATATACATTGACCGTCAACAACTTTATGGCGACGGCGACA
GGAGCCAAATATCAGCCAATCGGACTGCTGGGAAAAAATCCGGTGACAGGGCCTGAGGATTTGGAAGCGACAGTTGAGTA
CGTGAAGAGTTTTGATGAGCCAATTGCGTATACAAAAGAGGGAAGAATTAAGCTTGCTGAAGCCAGTGATATTGAAGACC
CTGTAACAGAAGACCCGATAACGGAAGAGCCTGGAGATGATCCGGGGACGGAGGATCCGATTAAAGAGGATCCAAGGCCA
GGTGAAGATTTGCCTGATATAAAAGAAACTCCGGGAACAGCACCGGTTCATCAGCTTCCGCCTTCAGCCATTTCGAGATT
CAATGAAATACCAATCAACAACACAAAAACCGCTGATACTGCTAATAGCATCAGCACATTGCCGTTACAAACCGAGACTG
CGGAAAGCGGGTCTGATCATCAGCTTCCGGATACGTCAGCGGGCTACTATAACTTTATGGTAATCGGTGCGGCGGTGACA
TTGTCAGGAACTTATCTATATGTCAGAAGAAAAAGGAGCGCCTCCAGAACGTGA

Upstream 100 bases:

>100_bases
CTGATTGAACTGATCCAAACCGAATTCCTCCTTTTTTTTCAGATCAGCTGTATTTTGTGTCAGTCTGCCGTGTATTATGC
AGAAGCCTGAAAGGAATTAT

Downstream 100 bases:

>100_bases
AAAAAGTTATTCCACTATTCATCATTGCTGCCGGCCTAGTGATCGCAGGCTATGGAGGCTTTAAATTGATCGATACGAAT
ACGAAAACGGAACAGACATT

Product: non specific extracellular endonuclease cleaving RNA and DNA

Products: Phosphate; Uridine [C]

Alternate protein names: NA

Number of amino acids: Translated: 1217; Mature: 1217

Protein sequence:

>1217_residues
MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAV
SPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNV
TDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKI
TSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAM
TLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGT
TKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKN
GYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAV
ENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNS
LIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKM
KSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQNGN
AITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPD
VSASAILKKYETIAEPIISEVVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLY
NIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTLTVNNFMATAT
GAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRP
GEDLPDIKETPGTAPVHQLPPSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVT
LSGTYLYVRRKRSASRT

Sequences:

>Translated_1217_residues
MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAV
SPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNV
TDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKI
TSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAM
TLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGT
TKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKN
GYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAV
ENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNS
LIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKM
KSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQNGN
AITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPD
VSASAILKKYETIAEPIISEVVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLY
NIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTLTVNNFMATAT
GAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRP
GEDLPDIKETPGTAPVHQLPPSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVT
LSGTYLYVRRKRSASRT
>Mature_1217_residues
MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAV
SPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNV
TDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKI
TSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAM
TLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGT
TKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKN
GYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAV
ENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNS
LIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKM
KSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQNGN
AITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPD
VSASAILKKYETIAEPIISEVVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLY
NIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTLTVNNFMATAT
GAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRP
GEDLPDIKETPGTAPVHQLPPSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVT
LSGTYLYVRRKRSASRT

Specific function: Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TNase-like domain

Homologues:

Organism=Homo sapiens, GI4505467, Length=552, Percent_Identity=23.1884057971014, Blast_Score=97, Evalue=1e-19,
Organism=Escherichia coli, GI1786687, Length=526, Percent_Identity=27.3764258555133, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1790658, Length=300, Percent_Identity=26.3333333333333, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19921980, Length=466, Percent_Identity=26.8240343347639, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24652512, Length=466, Percent_Identity=26.1802575107296, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI161076508, Length=466, Percent_Identity=26.8240343347639, Blast_Score=131, Evalue=3e-30,
Organism=Drosophila melanogaster, GI221329836, Length=561, Percent_Identity=23.5294117647059, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641187, Length=561, Percent_Identity=24.4206773618538, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922446, Length=445, Percent_Identity=25.8426966292135, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654424, Length=445, Percent_Identity=25.8426966292135, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19922444, Length=559, Percent_Identity=24.865831842576, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573524, Length=432, Percent_Identity=22.2222222222222, Blast_Score=83, Evalue=1e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): YHCR_BACSU (P54602)

Other databases:

- EMBL:   X96983
- EMBL:   AL009126
- PIR:   F69823
- RefSeq:   NP_388800.1
- ProteinModelPortal:   P54602
- EnsemblBacteria:   EBBACT00000002307
- GeneID:   936241
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09190
- NMPDR:   fig|224308.1.peg.919
- GenoList:   BSU09190
- GeneTree:   EBGT00050000000173
- HOGENOM:   HBG345522
- OMA:   SNDGDTP
- PhylomeDB:   P54602
- ProtClustDB:   CLSK886941
- BioCyc:   BSUB:BSU09190-MONOMER
- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR016071
- InterPro:   IPR006021
- Gene3D:   G3DSA:3.90.780.10
- Gene3D:   G3DSA:2.40.50.90
- PANTHER:   PTHR11575
- PRINTS:   PR01607
- SMART:   SM00318
- TIGRFAMs:   TIGR01167

Pfam domain/function: PF02872 5_nucleotid_C; PF00746 Gram_pos_anchor; PF00149 Metallophos; PF00565 SNase; PF01336 tRNA_anti; SSF55816 5'-Nucleotdase_C; SSF50249 Nucleic_acid_OB; SSF50199 Staphylococal_nuclease_OB-fold

EC number: 3.6.1.45; 3.1.3.5 [C]

Molecular weight: Translated: 132688; Mature: 132688

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00785 5_NUCLEOTIDASE_1; PS00786 5_NUCLEOTIDASE_2; PS01123 TNASE_1; PS01284 TNASE_2; PS50830 TNASE_3

Important sites: ACT_SITE 404-404 ACT_SITE 412-412 ACT_SITE 460-460 BINDING 965-965

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEK
CCCHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AIQQKEGQALVEGYAVGQAVSPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAF
HHHHHCCCHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCHHH
RSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNVTDDTKTPPAEQQVTINEARG
HHHCCCCCCCEEECEEEEEEECHHHHHCCCCCCCCEECCCCCCCCCCCCCCEEEHHHHCC
RLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKI
CCCCCEEEEEEEEECCCCCCCCHHHHEEECCCCCEEEECCCHHHHHHHHCCCCEEEEECC
TSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIP
CCHHHHHHHCCCCCCEEEECCCCCCCCCCCEEHHHHHCCCCCCCCCCEEEEEEEHHHHCC
SSPAGGGYNVTMIDDDHHAMTLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSA
CCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCC
DLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGTTKIRFVNVDAPETYHTPKND
CCEEHCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
ADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKN
CCHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEC
GYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRY
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHCCCCCEEE
VGDSSNKTYVQPADWKKIAVENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHG
CCCCCCCEEECCCCCCEEEEECEEEEEECCCHHHCCCCHHCCCCCCCCCEEEEEECCCCC
KIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNSLIVHAGDMIGGSSPVSSLLQ
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHC
DEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKM
CCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCEE
KSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELK
CCCCCCCCCCEEEEECCCCCEEEEEHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHH
KKGVKAIAVLAHMSAEQNGNAITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQ
HCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCEEEEE
AFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPDVSASAILKKYETIAEPIISE
EECCCCEEEEEEEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
VVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLY
HHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCCCC
NIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGT
CCCHHHHHHEEEEECCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCC
EIQPDATYTLTVNNFMATATGAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKE
CCCCCCEEEEEECCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCC
GRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRPGEDLPDIKETPGTAPVHQLP
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHCCC
PSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVT
HHHHHHHHCCCCCCCCCCCCCCCCEECCEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEE
LSGTYLYVRRKRSASRT
ECCEEEEEEECCCCCCC
>Mature Secondary Structure
MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEK
CCCHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AIQQKEGQALVEGYAVGQAVSPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAF
HHHHHCCCHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCHHH
RSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNVTDDTKTPPAEQQVTINEARG
HHHCCCCCCCEEECEEEEEEECHHHHHCCCCCCCCEECCCCCCCCCCCCCCEEEHHHHCC
RLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKI
CCCCCEEEEEEEEECCCCCCCCHHHHEEECCCCCEEEECCCHHHHHHHHCCCCEEEEECC
TSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIP
CCHHHHHHHCCCCCCEEEECCCCCCCCCCCEEHHHHHCCCCCCCCCCEEEEEEEHHHHCC
SSPAGGGYNVTMIDDDHHAMTLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSA
CCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCC
DLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGTTKIRFVNVDAPETYHTPKND
CCEEHCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
ADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKN
CCHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEC
GYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRY
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHCCCCCEEE
VGDSSNKTYVQPADWKKIAVENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHG
CCCCCCCEEECCCCCCEEEEECEEEEEECCCHHHCCCCHHCCCCCCCCCEEEEEECCCCC
KIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNSLIVHAGDMIGGSSPVSSLLQ
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHC
DEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKM
CCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCEE
KSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELK
CCCCCCCCCCEEEEECCCCCEEEEEHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHH
KKGVKAIAVLAHMSAEQNGNAITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQ
HCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCEEEEE
AFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPDVSASAILKKYETIAEPIISE
EECCCCEEEEEEEEECCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
VVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLY
HHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCCCC
NIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGT
CCCHHHHHHEEEEECCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCC
EIQPDATYTLTVNNFMATATGAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKE
CCCCCCEEEEEECCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCC
GRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRPGEDLPDIKETPGTAPVHQLP
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHCCC
PSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVT
HHHHHHHHCCCCCCCCCCCCCCCCEECCEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEE
LSGTYLYVRRKRSASRT
ECCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; UMP [C]

Specific reaction: H2O + UMP --> Phosphate + Uridine [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Inhibitor from Salmonella typhimurium cytoplasm [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377