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The map label for this gene is yfhA

Identifier: 16077913

GI number: 16077913

Start: 921472

End: 922503

Strand: Direct

Name: yfhA

Synonym: BSU08460

Alternate gene names: 16077913

Gene position: 921472-922503 (Clockwise)

Preceding gene: 16077912

Following gene: 16077914

Centisome position: 21.86

GC content: 48.64

Gene sequence:

>1032_bases
ATGAAACTTCGTTTTGGCGTTACTGCGGCTGAAAAGAAAGCATGGATCGTCTTTTTGGTTTTACTGGGGTTAACAGCTGC
TGTACTCATCATAAGCGCTGGTCTCGGACAAAGGTTTATTCCTCCCTGGGATGTAGCAAAAACATTCTTTGGTGCAGGTT
CCAAGCTGGATGAACTGATGATCATGTCGTTCCGCATGCCAAGAATTTTGACGGCTTTATGCGCCGGTGTCTGCTTGGCA
GCGGCAGGCGCGATATTGCAGGGGCTCGTCAGAAACCCTCTCGCATCTCCGGATATTATCGGAATAACAGGAGGAGCGGC
GGTAGCGGTCGTGCTTTTAATGATGTTCTTCTCAGACCGCAGCAGTTCACTTACGATCAGTCTGTCATGGCTTCCAGCAG
CCGCATTTATCGGCGCATCGGCTGTCGGGCTCATCGTCTATTTACTGGCATACAAAAATGGCGCCTCCACATTTCGGCTG
GTGCTTATCGGAATCGGATTTTCAATGTCGGCGCAGGCGATGACTACCCTGTTGATGATCAAAGGCCCGATTTACCGAGC
ATCACAAGCCAATGTGTATATCACTGGGTCAGTTTATGGGTCAAACTGGCAGCATGTAAAAATAGCTATTATCTTATCTG
TCATTCTCTTATTCATTTGTTTTGTCGCGCTAAAAAATATGAATATACAGGTGCTGGGTGAAGATATTGCGGCGGGTGCA
GGAAGCGCTGTGCAGCGAAATCGTTTTTTCTTGCTCCTTTTGAGTACGGCTCTTACTGGTTGTGCAGTTTCAGTTGCCGG
CACAATCGGTTTTGTCGGGCTGATGGCGCCCCATATTGCAAGACGGCTTGTCGGCTCATCTTATGGCGCGCTGCTCCCAG
CGTCGGCACTTATTGGAGCTCTGCTCGTTTTAACAGCTGATATCGTCGGCAGAACCTTATTTGCTCCGGTGGAAGTGCCG
GCCGGCGTCTTTACAGCGGCTATCGGCGCACCTTATTTTATTTATTTGCTCTATAAAACAAGAAATTCTTAA

Upstream 100 bases:

>100_bases
CGCGATATATCATTATGCCTCAGGAAGTTCCTGTCGGGGTCATGACCGCCATCATCGGAATGCCTGTGTTTGTGTACATC
GCAAGAAGGGGGGCGAAGCT

Downstream 100 bases:

>100_bases
TCGTTACACCCATTTTCTTAAAAAAGAAAATGGGTTTTTTTGATAATGACTGAAGATTCGTAATTATTTTTGCTATACTG
ACAGAGACATTGATAAAGAA

Product: iron(III) siderophore transport permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWDVAKTFFGAGSKLDELMIMSFRMPRILTALCAGVCLA
AAGAILQGLVRNPLASPDIIGITGGAAVAVVLLMMFFSDRSSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRL
VLIGIGFSMSAQAMTTLLMIKGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLFICFVALKNMNIQVLGEDIAAGA
GSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMAPHIARRLVGSSYGALLPASALIGALLVLTADIVGRTLFAPVEVP
AGVFTAAIGAPYFIYLLYKTRNS

Sequences:

>Translated_343_residues
MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWDVAKTFFGAGSKLDELMIMSFRMPRILTALCAGVCLA
AAGAILQGLVRNPLASPDIIGITGGAAVAVVLLMMFFSDRSSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRL
VLIGIGFSMSAQAMTTLLMIKGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLFICFVALKNMNIQVLGEDIAAGA
GSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMAPHIARRLVGSSYGALLPASALIGALLVLTADIVGRTLFAPVEVP
AGVFTAAIGAPYFIYLLYKTRNS
>Mature_343_residues
MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWDVAKTFFGAGSKLDELMIMSFRMPRILTALCAGVCLA
AAGAILQGLVRNPLASPDIIGITGGAAVAVVLLMMFFSDRSSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRL
VLIGIGFSMSAQAMTTLLMIKGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLFICFVALKNMNIQVLGEDIAAGA
GSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMAPHIARRLVGSSYGALLPASALIGALLVLTADIVGRTLFAPVEVP
AGVFTAAIGAPYFIYLLYKTRNS

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable)

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1790740, Length=302, Percent_Identity=38.7417218543046, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786347, Length=296, Percent_Identity=38.8513513513513, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786804, Length=291, Percent_Identity=34.7079037800687, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788004, Length=304, Percent_Identity=33.5526315789474, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786805, Length=311, Percent_Identity=34.4051446945338, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1790741, Length=301, Percent_Identity=32.890365448505, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFHA_BACSU (O31569)

Other databases:

- EMBL:   D85082
- EMBL:   AL009126
- PIR:   B69800
- RefSeq:   NP_388727.1
- HSSP:   P06609
- ProteinModelPortal:   O31569
- SMR:   O31569
- EnsemblBacteria:   EBBACT00000001269
- GeneID:   939714
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08460
- NMPDR:   fig|224308.1.peg.846
- GenoList:   BSU08460
- GeneTree:   EBGT00070000031905
- HOGENOM:   HBG700016
- OMA:   PLTKSRV
- PhylomeDB:   O31569
- ProtClustDB:   CLSK886903
- BioCyc:   BSUB:BSU08460-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 35956; Mature: 35956

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd7973b0)-; HASH(0xd188028)-; HASH(0xd406028)-; HASH(0xd9913a4)-; HASH(0xc3981b8)-; HASH(0xd8f39d4)-; HASH(0xdb73958)-; HASH(0xcca2660)-; HASH(0xd506abc)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWDVAKTFFGAGSKLDELM
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHH
IMSFRMPRILTALCAGVCLAAAGAILQGLVRNPLASPDIIGITGGAAVAVVLLMMFFSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCC
SSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRLVLIGIGFSMSAQAMTTLLMI
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
KGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLFICFVALKNMNIQVLGEDIAAGA
CCCCEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCC
GSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMAPHIARRLVGSSYGALLPASALIGA
CCHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLVLTADIVGRTLFAPVEVPAGVFTAAIGAPYFIYLLYKTRNS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEEECCH
>Mature Secondary Structure
MKLRFGVTAAEKKAWIVFLVLLGLTAAVLIISAGLGQRFIPPWDVAKTFFGAGSKLDELM
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHH
IMSFRMPRILTALCAGVCLAAAGAILQGLVRNPLASPDIIGITGGAAVAVVLLMMFFSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCC
SSSLTISLSWLPAAAFIGASAVGLIVYLLAYKNGASTFRLVLIGIGFSMSAQAMTTLLMI
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
KGPIYRASQANVYITGSVYGSNWQHVKIAIILSVILLFICFVALKNMNIQVLGEDIAAGA
CCCCEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCC
GSAVQRNRFFLLLLSTALTGCAVSVAGTIGFVGLMAPHIARRLVGSSYGALLPASALIGA
CCHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLVLTADIVGRTLFAPVEVPAGVFTAAIGAPYFIYLLYKTRNS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377