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The map label for this gene is murQ

Identifier: 16077238

GI number: 16077238

Start: 192051

End: 192965

Strand: Reverse

Name: murQ

Synonym: BSU01700

Alternate gene names: 16077238

Gene position: 192965-192051 (Counterclockwise)

Preceding gene: 255767045

Following gene: 16077237

Centisome position: 4.58

GC content: 47.76

Gene sequence:

>915_bases
ATGTCAGAACCATTAAACCTTCACCGTCTTACAACGGAATCACGCAATAGTCAAACAGTTGAAATCCACAAAGCAAACAC
TCTCGGCATCCTTAAAATGATCAACAACGAAGATATGAAAGTCGCTGCAGCCGTTCAGGAGGTTCTCCCCGACATCAAAA
CAGCTGTAGACTGCGCATATGAATCGTTTCAAAATGGAGGCCGGCTCATATATACAGGCGCCGGCACAAGCGGCAGACTC
GGCGTCATGGATGCTGTTGAATGTCCTCCCACCTACAGCGTAAGCCCAGATCAGGTCATCGGAATCATGGCTGGAGGCCC
CGAAGCCTTTTTACAGGCAGCAGAGGGCATTGAAGACAGTGAAGAAGCAGGAGCTGAAGATTTAAGAAACATACAGCTCA
CTTCAAATGACACCGTCATTGCCATCGCAGCAAGCGGCCGCACACCCTACGCCGCAGGCGCCCTAAGATACGCCCGTAAA
GTCGGAGCACACACCATCGCCCTTACTTGCAATGAAAATTCCGCCATCAGCAAGGATGCGGATCACAGCATTGAGGTTGT
CGTCGGACCTGAGGCCATTACAGGATCAACACGTATGAAAGCCGCAACCGCTCATAAAATGATTCTAAACATGATATCTA
CCGCTGTAATGGTCAAAATCGGCAAGGTTTACGAAAACTTGATGGTAGACGTCAACGTCAGCAACAAAAAACTAAAAGAA
CGCGCCATCAGCATCATCCAAAGCCTTACAAACGCTTCATACGACACAGCCAGATACACTCTGGAACAAGCCGATCATCA
CGTCAAAACAGCAATCGTCATGCTCAAAACAAGCACAGATCAGAAACAAGCACAGACATTACTCGATGAAGCAAACGGTT
TCATTGACAAAGCAATCGAACATTACCATCCATGA

Upstream 100 bases:

>100_bases
AAATAAAATTTCAAAAATTTAAAAACATAGTTGAAATATCATAACAGAAATGAATATACTGAATATTGAGATATATCATT
TTAAAACAGGGGGCATCCTC

Downstream 100 bases:

>100_bases
TAAGGAGAGAACTAGAATGGCCACAGGCGGTTTAGCGATCATCCAATCAATGAAGCATAAGCTCCCTCCATCCGAGCGCA
AACTTGCAGATTATATCCTA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSEPLNLHRLTTESRNSQTVEIHKANTLGILKMINNEDMKVAAAVQEVLPDIKTAVDCAYESFQNGGRLIYTGAGTSGRL
GVMDAVECPPTYSVSPDQVIGIMAGGPEAFLQAAEGIEDSEEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARK
VGAHTIALTCNENSAISKDADHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMVKIGKVYENLMVDVNVSNKKLKE
RAISIIQSLTNASYDTARYTLEQADHHVKTAIVMLKTSTDQKQAQTLLDEANGFIDKAIEHYHP

Sequences:

>Translated_304_residues
MSEPLNLHRLTTESRNSQTVEIHKANTLGILKMINNEDMKVAAAVQEVLPDIKTAVDCAYESFQNGGRLIYTGAGTSGRL
GVMDAVECPPTYSVSPDQVIGIMAGGPEAFLQAAEGIEDSEEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARK
VGAHTIALTCNENSAISKDADHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMVKIGKVYENLMVDVNVSNKKLKE
RAISIIQSLTNASYDTARYTLEQADHHVKTAIVMLKTSTDQKQAQTLLDEANGFIDKAIEHYHP
>Mature_303_residues
SEPLNLHRLTTESRNSQTVEIHKANTLGILKMINNEDMKVAAAVQEVLPDIKTAVDCAYESFQNGGRLIYTGAGTSGRLG
VMDAVECPPTYSVSPDQVIGIMAGGPEAFLQAAEGIEDSEEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARKV
GAHTIALTCNENSAISKDADHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMVKIGKVYENLMVDVNVSNKKLKER
AISIIQSLTNASYDTARYTLEQADHHVKTAIVMLKTSTDQKQAQTLLDEANGFIDKAIEHYHP

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=296, Percent_Identity=47.6351351351351, Blast_Score=296, Evalue=9e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_BACSU (Q45582)

Other databases:

- EMBL:   AB002150
- EMBL:   AL009126
- PIR:   D69744
- RefSeq:   NP_388051.1
- ProteinModelPortal:   Q45582
- SMR:   Q45582
- PhosSite:   Q45582
- EnsemblBacteria:   EBBACT00000002042
- GeneID:   938882
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU01700
- NMPDR:   fig|224308.1.peg.170
- GenoList:   BSU01700
- GeneTree:   EBGT00050000002902
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- PhylomeDB:   Q45582
- ProtClustDB:   PRK05441
- BioCyc:   BSUB:BSU01700-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32700; Mature: 32569

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 87-87 ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLNLHRLTTESRNSQTVEIHKANTLGILKMINNEDMKVAAAVQEVLPDIKTAVDCAY
CCCCCCCEEEECCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ESFQNGGRLIYTGAGTSGRLGVMDAVECPPTYSVSPDQVIGIMAGGPEAFLQAAEGIEDS
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCC
EEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARKVGAHTIALTCNENSAISKDA
HHCCHHHHCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
DHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMVKIGKVYENLMVDVNVSNKKLKE
CCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHH
RAISIIQSLTNASYDTARYTLEQADHHVKTAIVMLKTSTDQKQAQTLLDEANGFIDKAIE
HHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHH
HYHP
HCCC
>Mature Secondary Structure 
SEPLNLHRLTTESRNSQTVEIHKANTLGILKMINNEDMKVAAAVQEVLPDIKTAVDCAY
CCCCCCEEEECCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ESFQNGGRLIYTGAGTSGRLGVMDAVECPPTYSVSPDQVIGIMAGGPEAFLQAAEGIEDS
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCC
EEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARKVGAHTIALTCNENSAISKDA
HHCCHHHHCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
DHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMVKIGKVYENLMVDVNVSNKKLKE
CCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHH
RAISIIQSLTNASYDTARYTLEQADHHVKTAIVMLKTSTDQKQAQTLLDEANGFIDKAIE
HHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHH
HYHP
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377