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The map label for this gene is rpe

Identifier: 15618109

GI number: 15618109

Start: 221762

End: 222451

Strand: Reverse

Name: rpe

Synonym: CPn0185

Alternate gene names: 15618109

Gene position: 222451-221762 (Counterclockwise)

Preceding gene: 15618115

Following gene: 15618108

Centisome position: 18.08

GC content: 38.41

Gene sequence:

>690_bases
GTGAAGAAACAGGAATCCGTATTAGTTGGCCCTTCGATTATGGGGGCAGATCTTACCTGTTTGGGTGTAGAAGCAAAAAA
ACTAGAGCAGGCGGGAAGTGATTTTATACACATAGATATCATGGATGGCCACTTTGTTCCGAACCTTACTTTTGGTCCAG
GGATCATTGCTGCCATTAATAGATCTACGGATCTATTTTTAGAAGTCCACGCTATGATTTACAATCCTTTTGAATTTATA
GAAAGTTTCGTTCGTTCTGGTGCGGATAGAATTATAGTACACTTTGAAGCTTCAGAGGATATAAAAGAGCTTCTATCTTA
TATAAAAAAATGTGGGGTTCAAGCGGGTCTAGCTTTTTCTCCCGATACTTCAATCGAATTTCTTCCTTCTTTCCTTCCGT
TTTGTGATGTCGTTGTGCTAATGTCAGTTTATCCGGGATTTACAGGACAGAGCTTTTTACCAAATACAATAGAAAAGATT
GCTTTTGCACGTCATGCGATAAAGACTTTAGGTTTAAAGGATTCTTGTTTAATAGAAGTAGATGGAGGCATAGATCAGCA
ATCTGCGCCGTTATGTCGAGATGCAGGAGCAGATATTTTAGTCACAGCTTCTTACTTATTCGAAGCAGATTCATTAGCAA
TGGAAGATAAAATTTTGTTGCTGCGAGGAGAAAATTATGGTGTTAAGTAG

Upstream 100 bases:

>100_bases
AGTAGGAGTTCATGAATACATCAACCAGTAAATATAAATAGTAGAAAGTTAAAGCTCACTCTACTTTAAATTTAGCGTAG
TGAAGTTGAGATAGGCTGAG

Downstream 100 bases:

>100_bases
CCAATTATCCGTAGGGATGTTTATTTCTACAAAGGACGGTCTTTATAAAGTAACCTCAGTGTCTAAGGTGGCAGGGCCCA
AAGGCGAATCCTTCATTAAA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTFGPGIIAAINRSTDLFLEVHAMIYNPFEFI
ESFVRSGADRIIVHFEASEDIKELLSYIKKCGVQAGLAFSPDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSFLPNTIEKI
AFARHAIKTLGLKDSCLIEVDGGIDQQSAPLCRDAGADILVTASYLFEADSLAMEDKILLLRGENYGVK

Sequences:

>Translated_229_residues
MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTFGPGIIAAINRSTDLFLEVHAMIYNPFEFI
ESFVRSGADRIIVHFEASEDIKELLSYIKKCGVQAGLAFSPDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSFLPNTIEKI
AFARHAIKTLGLKDSCLIEVDGGIDQQSAPLCRDAGADILVTASYLFEADSLAMEDKILLLRGENYGVK
>Mature_229_residues
MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTFGPGIIAAINRSTDLFLEVHAMIYNPFEFI
ESFVRSGADRIIVHFEASEDIKELLSYIKKCGVQAGLAFSPDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSFLPNTIEKI
AFARHAIKTLGLKDSCLIEVDGGIDQQSAPLCRDAGADILVTASYLFEADSLAMEDKILLLRGENYGVK

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family

Homologues:

Organism=Homo sapiens, GI40385883, Length=204, Percent_Identity=34.3137254901961, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI219879828, Length=204, Percent_Identity=32.3529411764706, Blast_Score=141, Evalue=4e-34,
Organism=Homo sapiens, GI24307923, Length=160, Percent_Identity=28.125, Blast_Score=85, Evalue=6e-17,
Organism=Escherichia coli, GI1789788, Length=202, Percent_Identity=39.1089108910891, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=32.48730964467, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790754, Length=178, Percent_Identity=30.3370786516854, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17552948, Length=213, Percent_Identity=37.5586854460094, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=215, Percent_Identity=34.8837209302326, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24586301, Length=202, Percent_Identity=37.1287128712871, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPE_CHLPN (Q9Z8Z9)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   A86514
- PIR:   H72110
- RefSeq:   NP_224394.1
- RefSeq:   NP_300244.1
- RefSeq:   NP_445126.1
- RefSeq:   NP_876464.1
- ProteinModelPortal:   Q9Z8Z9
- SMR:   Q9Z8Z9
- GeneID:   1466871
- GeneID:   894913
- GeneID:   918981
- GeneID:   963763
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0583
- KEGG:   cpn:CPn0185
- KEGG:   cpt:CpB0188
- TIGR:   CP_0583
- HOGENOM:   HBG571751
- OMA:   KHIHGAL
- ProtClustDB:   PRK05581
- BioCyc:   CPNE115711:CP_0583-MONOMER
- BioCyc:   CPNE115713:CPN0185-MONOMER
- BioCyc:   CPNE138677:CPJ0185-MONOMER
- BioCyc:   CPNE182082:CPB0188-MONOMER
- BRENDA:   5.1.3.1
- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR11749
- PIRSF:   PIRSF001461
- TIGRFAMs:   TIGR01163

Pfam domain/function: PF00834 Ribul_P_3_epim; SSF51366 RibP_bind_barrel

EC number: =5.1.3.1

Molecular weight: Translated: 24987; Mature: 24987

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTFGPGIIAAIN
CCCCCCEEECCCCCCCCEEEECCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEC
RSTDLFLEVHAMIYNPFEFIESFVRSGADRIIVHFEASEDIKELLSYIKKCGVQAGLAFS
CCCHHHEEHHHHHCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEC
PDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSFLPNTIEKIAFARHAIKTLGLKDSCLIEV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
DGGIDQQSAPLCRDAGADILVTASYLFEADSLAMEDKILLLRGENYGVK
CCCCCCCCCCCHHHCCCCEEEEHHHHHCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTFGPGIIAAIN
CCCCCCEEECCCCCCCCEEEECCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEC
RSTDLFLEVHAMIYNPFEFIESFVRSGADRIIVHFEASEDIKELLSYIKKCGVQAGLAFS
CCCHHHEEHHHHHCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEC
PDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSFLPNTIEKIAFARHAIKTLGLKDSCLIEV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
DGGIDQQSAPLCRDAGADILVTASYLFEADSLAMEDKILLLRGENYGVK
CCCCCCCCCCCHHHCCCCEEEEHHHHHCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362