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The map label for this gene is htrB

Identifier: 15618022

GI number: 15618022

Start: 126088

End: 127491

Strand: Reverse

Name: htrB

Synonym: CPn0098

Alternate gene names: 15618022

Gene position: 127491-126088 (Counterclockwise)

Preceding gene: 15618024

Following gene: 15618020

Centisome position: 10.36

GC content: 39.03

Gene sequence:

>1404_bases
GTGGGCAAAAAATTCCATCAGATCAAGAGAACAATCCTAGAAGCCCCTCTGTATTACCTAGTCTCTGGTATTATTGCTTT
ATGCAGGCATACCCCAAGATCTTTTTTAACAGGATTAGGAAAAGGTTTTGGATTTCTAGCCTTTTATATCATCAGCGATT
ATCGAAAAACAGCCCTCACAAACTTAGCATTAGCGTTTCCAGAAAAAACATTTGATGAGCGTTATAAAATAGCTCGTCAA
TCTTTGCAGCATCTTATAATTACACTCTTAGAATTACTCGCAATCGAGCAACTTGTCGGAAATATAGACAAACTCATTAC
AATCGTGACATCCTCACGAAACCCCAAAGGTTTTTCTTCTGAAGAGGTCATTTCCAATGAAGATTTAGAGGAAACTTTTA
AGAATCTACAAGAGAAGCAGGGCCTTATTTTATTTTGTGGCCACCAGGCAAACTGGGAACTTCCTTTTCTTTATATCACT
AAAAACTATCCTGGAATCGCCTTTGCTAAGGCTATAAAAAATCAAAGGCTCAGCAAGAAAATCTTTGCTCTTAGAGAAGT
TTTCAAAGGTAAGATTGTACCCCCAAAAAACGGAATCCAACAGGGCATAGAAGCTCTGAATCAAGGGAAACTCGTGGGGA
TTGTTGGAGATCAAGCCTTGTTGATGTCTTCATACACGTATCCTCTCTTTGGCTCTCCAGCATTCACAACGACATCTCCA
GCACTATTAGCTTATAAAACAGGTTTTCCTGTGATTGCTGTTAATGTTTCTCGCCAAGCTAAAGGCTTCGAAGTGATTCC
GAGTGCCAAGCTGTATGCTAATAAAAGCCTCCCTATGAAAGAATCCGTGGCTATCCTTATGGATCAGATGATGGGATTTT
TAGAAAAAGGGATCGCCAGTCAGCCTGAACAATGGATGTGGATTCATAAAAGGTGGAAGAGAAAGATCTCTAACGTAATA
AAAAAGAAGTACCGCTATAGCCATATTCTAGTTTTTGTAGATCAAGTCTCCTCACACTTTTCTTTTCTGAAAGCTCTAGC
AGAATGCTTTTCAGGAACCACTCTTCATCTAGCACTAGGAAATGCGGATCATCTTGAAGAACTTCAAGAACAATTCCCAG
AGTACTCCTTGATCCAACTCCGAAATGATCAAGACATTCTAGCTCTACCGAATTGCTATCCTGCTATTTTTGATCTCACT
AACAATCTACAGCATTTATACAAGCATTTTAGAAAAACAGGTTCTTGTGCTGTGTACTCTAAAAGATTCCTAGAAAAATC
TCTAGACCACCCCCAAGCTCCTCTAAAAAACTCTTTGAGGATCTTCTATTCTAAAAATCTTAAAGATAAAGAGAGAAAAA
ACTTCAAGGTGAAGTCGAAGGGGCCCCGACTTACAGTGGAGTAA

Upstream 100 bases:

>100_bases
TTCCTTTCTGGAGCGTGCTTCGCTGCAAAACGAGAAATCTTGAGATAGTAAGAAGCACAATAGTATTATTTAAAGTGATT
TGCGAAAGTCAAATTAGCTT

Downstream 100 bases:

>100_bases
AAGCCCTAATTCATATTTACGAAAACATCTGTATATTCTCGAAAAATTTGCGAAGTCCTGGATTTTAAAGCAAAAATTCT
AGGTTTCAGGAAATTCCGAC

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Lauroyl/Myristoyl Acyltransferase

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MGKKFHQIKRTILEAPLYYLVSGIIALCRHTPRSFLTGLGKGFGFLAFYIISDYRKTALTNLALAFPEKTFDERYKIARQ
SLQHLIITLLELLAIEQLVGNIDKLITIVTSSRNPKGFSSEEVISNEDLEETFKNLQEKQGLILFCGHQANWELPFLYIT
KNYPGIAFAKAIKNQRLSKKIFALREVFKGKIVPPKNGIQQGIEALNQGKLVGIVGDQALLMSSYTYPLFGSPAFTTTSP
ALLAYKTGFPVIAVNVSRQAKGFEVIPSAKLYANKSLPMKESVAILMDQMMGFLEKGIASQPEQWMWIHKRWKRKISNVI
KKKYRYSHILVFVDQVSSHFSFLKALAECFSGTTLHLALGNADHLEELQEQFPEYSLIQLRNDQDILALPNCYPAIFDLT
NNLQHLYKHFRKTGSCAVYSKRFLEKSLDHPQAPLKNSLRIFYSKNLKDKERKNFKVKSKGPRLTVE

Sequences:

>Translated_467_residues
MGKKFHQIKRTILEAPLYYLVSGIIALCRHTPRSFLTGLGKGFGFLAFYIISDYRKTALTNLALAFPEKTFDERYKIARQ
SLQHLIITLLELLAIEQLVGNIDKLITIVTSSRNPKGFSSEEVISNEDLEETFKNLQEKQGLILFCGHQANWELPFLYIT
KNYPGIAFAKAIKNQRLSKKIFALREVFKGKIVPPKNGIQQGIEALNQGKLVGIVGDQALLMSSYTYPLFGSPAFTTTSP
ALLAYKTGFPVIAVNVSRQAKGFEVIPSAKLYANKSLPMKESVAILMDQMMGFLEKGIASQPEQWMWIHKRWKRKISNVI
KKKYRYSHILVFVDQVSSHFSFLKALAECFSGTTLHLALGNADHLEELQEQFPEYSLIQLRNDQDILALPNCYPAIFDLT
NNLQHLYKHFRKTGSCAVYSKRFLEKSLDHPQAPLKNSLRIFYSKNLKDKERKNFKVKSKGPRLTVE
>Mature_466_residues
GKKFHQIKRTILEAPLYYLVSGIIALCRHTPRSFLTGLGKGFGFLAFYIISDYRKTALTNLALAFPEKTFDERYKIARQS
LQHLIITLLELLAIEQLVGNIDKLITIVTSSRNPKGFSSEEVISNEDLEETFKNLQEKQGLILFCGHQANWELPFLYITK
NYPGIAFAKAIKNQRLSKKIFALREVFKGKIVPPKNGIQQGIEALNQGKLVGIVGDQALLMSSYTYPLFGSPAFTTTSPA
LLAYKTGFPVIAVNVSRQAKGFEVIPSAKLYANKSLPMKESVAILMDQMMGFLEKGIASQPEQWMWIHKRWKRKISNVIK
KKYRYSHILVFVDQVSSHFSFLKALAECFSGTTLHLALGNADHLEELQEQFPEYSLIQLRNDQDILALPNCYPAIFDLTN
NLQHLYKHFRKTGSCAVYSKRFLEKSLDHPQAPLKNSLRIFYSKNLKDKERKNFKVKSKGPRLTVE

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.-

Molecular weight: Translated: 53194; Mature: 53063

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKFHQIKRTILEAPLYYLVSGIIALCRHTPRSFLTGLGKGFGFLAFYIISDYRKTALT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
NLALAFPEKTFDERYKIARQSLQHLIITLLELLAIEQLVGNIDKLITIVTSSRNPKGFSS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
EEVISNEDLEETFKNLQEKQGLILFCGHQANWELPFLYITKNYPGIAFAKAIKNQRLSKK
HHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
IFALREVFKGKIVPPKNGIQQGIEALNQGKLVGIVGDQALLMSSYTYPLFGSPAFTTTSP
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCCCC
ALLAYKTGFPVIAVNVSRQAKGFEVIPSAKLYANKSLPMKESVAILMDQMMGFLEKGIAS
CCEEEECCCCEEEEECCCCCCCCEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QPEQWMWIHKRWKRKISNVIKKKYRYSHILVFVDQVSSHFSFLKALAECFSGTTLHLALG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEC
NADHLEELQEQFPEYSLIQLRNDQDILALPNCYPAIFDLTNNLQHLYKHFRKTGSCAVYS
CHHHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KRFLEKSLDHPQAPLKNSLRIFYSKNLKDKERKNFKVKSKGPRLTVE
HHHHHHHCCCCCCCHHHCEEEEEECCCCHHHHCCCEEECCCCCEECC
>Mature Secondary Structure 
GKKFHQIKRTILEAPLYYLVSGIIALCRHTPRSFLTGLGKGFGFLAFYIISDYRKTALT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
NLALAFPEKTFDERYKIARQSLQHLIITLLELLAIEQLVGNIDKLITIVTSSRNPKGFSS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
EEVISNEDLEETFKNLQEKQGLILFCGHQANWELPFLYITKNYPGIAFAKAIKNQRLSKK
HHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
IFALREVFKGKIVPPKNGIQQGIEALNQGKLVGIVGDQALLMSSYTYPLFGSPAFTTTSP
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCCCC
ALLAYKTGFPVIAVNVSRQAKGFEVIPSAKLYANKSLPMKESVAILMDQMMGFLEKGIAS
CCEEEECCCCEEEEECCCCCCCCEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QPEQWMWIHKRWKRKISNVIKKKYRYSHILVFVDQVSSHFSFLKALAECFSGTTLHLALG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEC
NADHLEELQEQFPEYSLIQLRNDQDILALPNCYPAIFDLTNNLQHLYKHFRKTGSCAVYS
CHHHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KRFLEKSLDHPQAPLKNSLRIFYSKNLKDKERKNFKVKSKGPRLTVE
HHHHHHHCCCCCCCHHHCEEEEEECCCCHHHHCCCEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA