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The map label for this gene is fucA2

Identifier: 15606975

GI number: 15606975

Start: 1392255

End: 1392881

Strand: Direct

Name: fucA2

Synonym: aq_1979

Alternate gene names: 15606975

Gene position: 1392255-1392881 (Clockwise)

Preceding gene: 15606974

Following gene: 15606977

Centisome position: 89.75

GC content: 45.14

Gene sequence:

>627_bases
GTGAACGTGGAACTCTTTAAGAAGTTTTCCGAAAAGGTAGAAGAAATTATAGAAGCCGGCAGGATTTTGCACTCAAGGGG
ATGGGTTCCCGCAACGAGCGGAAATATATCCGCAAAAGTAAGCGAGGAGTACATAGCGATAACAGCCTCAGGTAAGCACA
AAGGTAAGTTAACTCCCGAGGACATACTCCTTATAGATTACGAGGGAAGACCGGTTGGAGGAGGAAAGCCCTCCGCGGAA
ACGCTCCTTCACACCACCGTTTACAAGCTCTTTCCCGAGGTGAACGCCGTTGTTCACACCCACTCTCCGAACGCTACCGT
GATTTCCATCGTTGAAAAAAAAGACTTTGTAGAGCTTGAAGACTACGAACTCCTGAAGGCTTTTCCGGATATACACACCC
ACGAAGTGAAGATTAAAATTCCCATATTTCCGAACGAACAGAATATTCCTCTTCTTGCAAAAGAAGTTGAAAACTACTTC
AAAACCTCAGAAGACAAGTACGGTTTTCTAATAAGGGGGCACGGACTATACACCTGGGGAAGGAGTATGGAAGAAGCCCT
AATCCACACCGAGGCCCTTGAGTTTATCTTCGAATGTGAACTTAAACTCCTTTCTTTTCATTCTTAG

Upstream 100 bases:

>100_bases
AGGGAGCGGTTCACTTTTATAGGAACACAAGTGAGCTTTCCGTACTCCTTGCCATCTTCTCACCGAGTTACGACGGGAAG
GACAGTGTGAGGGTAGAGCT

Downstream 100 bases:

>100_bases
TTCTCCCTATAAGCATTTCCCTTTCCGCCTCACACTTCCCCAGTCTGTAACTCAAATCCTCTATCTTGTTAATGATTTCT
AAGAAATTCTCAGAAATTTT

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNVELFKKFSEKVEEIIEAGRILHSRGWVPATSGNISAKVSEEYIAITASGKHKGKLTPEDILLIDYEGRPVGGGKPSAE
TLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELEDYELLKAFPDIHTHEVKIKIPIFPNEQNIPLLAKEVENYF
KTSEDKYGFLIRGHGLYTWGRSMEEALIHTEALEFIFECELKLLSFHS

Sequences:

>Translated_208_residues
MNVELFKKFSEKVEEIIEAGRILHSRGWVPATSGNISAKVSEEYIAITASGKHKGKLTPEDILLIDYEGRPVGGGKPSAE
TLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELEDYELLKAFPDIHTHEVKIKIPIFPNEQNIPLLAKEVENYF
KTSEDKYGFLIRGHGLYTWGRSMEEALIHTEALEFIFECELKLLSFHS
>Mature_208_residues
MNVELFKKFSEKVEEIIEAGRILHSRGWVPATSGNISAKVSEEYIAITASGKHKGKLTPEDILLIDYEGRPVGGGKPSAE
TLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELEDYELLKAFPDIHTHEVKIKIPIFPNEQNIPLLAKEVENYF
KTSEDKYGFLIRGHGLYTWGRSMEEALIHTEALEFIFECELKLLSFHS

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=194, Percent_Identity=26.2886597938144, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1789094, Length=190, Percent_Identity=25.7894736842105, Blast_Score=73, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322484, Length=194, Percent_Identity=29.3814432989691, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859685, Length=216, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNB_AQUAE (O67788)

Other databases:

- EMBL:   AE000657
- PIR:   H70469
- RefSeq:   NP_214357.1
- PDB:   2IRP
- PDBsum:   2IRP
- ProteinModelPortal:   O67788
- SMR:   O67788
- GeneID:   1193685
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1979
- NMPDR:   fig|224324.1.peg.1372
- HOGENOM:   HBG337716
- OMA:   EFLFECE
- PhylomeDB:   O67788
- ProtClustDB:   PRK09220
- BioCyc:   AAEO224324:AQ_1979-MONOMER
- HAMAP:   MF_01677
- InterPro:   IPR001303
- InterPro:   IPR017714
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR03328

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.2.1.109

Molecular weight: Translated: 23550; Mature: 23550

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVELFKKFSEKVEEIIEAGRILHSRGWVPATSGNISAKVSEEYIAITASGKHKGKLTPE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCC
DILLIDYEGRPVGGGKPSAETLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELE
CEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCEECC
DYELLKAFPDIHTHEVKIKIPIFPNEQNIPLLAKEVENYFKTSEDKYGFLIRGHGLYTWG
CHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCEEEECC
RSMEEALIHTEALEFIFECELKLLSFHS
CCHHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MNVELFKKFSEKVEEIIEAGRILHSRGWVPATSGNISAKVSEEYIAITASGKHKGKLTPE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCC
DILLIDYEGRPVGGGKPSAETLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELE
CEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCEECC
DYELLKAFPDIHTHEVKIKIPIFPNEQNIPLLAKEVENYFKTSEDKYGFLIRGHGLYTWG
CHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCEEEECC
RSMEEALIHTEALEFIFECELKLLSFHS
CCHHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320