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The map label for this gene is rnhB

Identifier: 15606955

GI number: 15606955

Start: 1374521

End: 1375111

Strand: Direct

Name: rnhB

Synonym: aq_1955

Alternate gene names: 15606955

Gene position: 1374521-1375111 (Clockwise)

Preceding gene: 15606954

Following gene: 15606958

Centisome position: 88.6

GC content: 44.5

Gene sequence:

>591_bases
ATGCTTAATTACGAATTAGAACTTTGGGAAAAGGGTCTTTTAGTAGCTGGAGTTGACGAAGCGGGGAGAGGTCCACTGGC
CGGGCCCGTCGTCGCCGCTGCTGTCATACTTCCACCCTTCACGGAACCCTTTATAAAGGGCGATTCAAAGAAATTAACCA
AGAAAGAAAGGGAAGAGGCTTATGAGGAGATAAAAAACAAAGCCCTGGCTGTGGGAACGGCAGTTGTGGACAGTGCAGTC
ATAGACAGGGTGAACATACTCAGGGCCACGAAACTCGCCATGAAAAGGGCTCTCAAAGACTTGAAGTACCATTACGATAT
TGTCATCACAGATTACGTAAAGCTTGAAGGAGAAAACTGCATGCCTCTAGTAAAGGGAGATGAGAAAAGTCTAAACTGCG
CCTGCGCCTCTATTATCGCAAAGGTTATAAGGGACAAGATTATGGAGATTTATCACAAGATTTATCCGGATTTTAACTTT
GCTTCAAACAAGGGATATCCTTCAAAAACTCACCTGGAAAAGGTGGAGAAGGGAGAGTACACGGAGATACACAGGAAGAG
CTTTTCCCCCCTTAAGAAAAAACTTTTTTAG

Upstream 100 bases:

>100_bases
TGGGAATACGAGGCTATGCAAAGGAGAAAGGAAGAGGCGAGAAAGCAAAGGGAAGAAGAACAAAAGCAGGCTCAGGAGCA
GGCTCAAGAACAGGAACAGA

Downstream 100 bases:

>100_bases
GAAAATTGTTCAAGTTTTATCTTATGCTGTGTTAAATCAAGGAAGGCATACCTTCCTTCTTCAAACTCTCCGGGATTTAC
AACTATAGTGTTACCCACGA

Product: RNase HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLNYELELWEKGLLVAGVDEAGRGPLAGPVVAAAVILPPFTEPFIKGDSKKLTKKEREEAYEEIKNKALAVGTAVVDSAV
IDRVNILRATKLAMKRALKDLKYHYDIVITDYVKLEGENCMPLVKGDEKSLNCACASIIAKVIRDKIMEIYHKIYPDFNF
ASNKGYPSKTHLEKVEKGEYTEIHRKSFSPLKKKLF

Sequences:

>Translated_196_residues
MLNYELELWEKGLLVAGVDEAGRGPLAGPVVAAAVILPPFTEPFIKGDSKKLTKKEREEAYEEIKNKALAVGTAVVDSAV
IDRVNILRATKLAMKRALKDLKYHYDIVITDYVKLEGENCMPLVKGDEKSLNCACASIIAKVIRDKIMEIYHKIYPDFNF
ASNKGYPSKTHLEKVEKGEYTEIHRKSFSPLKKKLF
>Mature_196_residues
MLNYELELWEKGLLVAGVDEAGRGPLAGPVVAAAVILPPFTEPFIKGDSKKLTKKEREEAYEEIKNKALAVGTAVVDSAV
IDRVNILRATKLAMKRALKDLKYHYDIVITDYVKLEGENCMPLVKGDEKSLNCACASIIAKVIRDKIMEIYHKIYPDFNF
ASNKGYPSKTHLEKVEKGEYTEIHRKSFSPLKKKLF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=189, Percent_Identity=46.031746031746, Blast_Score=150, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_AQUAE (O67768)

Other databases:

- EMBL:   AE000657
- PIR:   D70467
- RefSeq:   NP_214337.1
- ProteinModelPortal:   O67768
- SMR:   O67768
- GeneID:   1193665
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1955
- NMPDR:   fig|224324.1.peg.1352
- HOGENOM:   HBG584843
- OMA:   RINIFHA
- PhylomeDB:   O67768
- ProtClustDB:   CLSK2299880
- BioCyc:   AAEO224324:AQ_1955-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22045; Mature: 22045

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYELELWEKGLLVAGVDEAGRGPLAGPVVAAAVILPPFTEPFIKGDSKKLTKKEREEA
CCCCCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHH
YEEIKNKALAVGTAVVDSAVIDRVNILRATKLAMKRALKDLKYHYDIVITDYVKLEGENC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCC
MPLVKGDEKSLNCACASIIAKVIRDKIMEIYHKIYPDFNFASNKGYPSKTHLEKVEKGEY
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCH
TEIHRKSFSPLKKKLF
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNYELELWEKGLLVAGVDEAGRGPLAGPVVAAAVILPPFTEPFIKGDSKKLTKKEREEA
CCCCCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHH
YEEIKNKALAVGTAVVDSAVIDRVNILRATKLAMKRALKDLKYHYDIVITDYVKLEGENC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCC
MPLVKGDEKSLNCACASIIAKVIRDKIMEIYHKIYPDFNFASNKGYPSKTHLEKVEKGEY
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCH
TEIHRKSFSPLKKKLF
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320