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The map label for this gene is argC

Identifier: 15606911

GI number: 15606911

Start: 1324806

End: 1325828

Strand: Direct

Name: argC

Synonym: aq_1879

Alternate gene names: 15606911

Gene position: 1324806-1325828 (Clockwise)

Preceding gene: 15606910

Following gene: 15606912

Centisome position: 85.4

GC content: 44.77

Gene sequence:

>1023_bases
ATGGAGCAAACGTTAAGAGTTTCCGTTTTCGGTGCCACCGGTTATACCGGTATAGAACTCCTTCGCTCCCTTCTCACACA
CCCCCACTTTGAAGTAAAAAACCTTATCTCTCAGTCTTACAAAGGCAAAAAAGTAAGGGAGGTACTTCCCTTCTTTTCAA
ACACCTACATATCCGAGATAGAGTTCCTTGAAGAACCTGTTGAAGACTACGAACTTGCCTTTTTATGCCTTCCTCACGAA
GTCTCCTACGAGATAGTTCCCAAACTGCTCTCCCAGGGCAAAAAGGTTGTGGACCTATCCGGTGCTTACAGGATAAAAAG
TCCCAAAGCTTACGAGGAATTTTACGGATTTAAACACGAGAGGGAAGATATCCTTCAGAGGGCTGTTTACGGACTTCCAG
AAGTTTTTAGAGAGGAGATAAAAAATAGCGATCTCGTGGCAAACCCCGGGTGTTATCCAACGGCTACACTTCTGGCAATA
TACCCCTTCCTCAAGGAAAGGGTGGGAATAGAGAGTGTAATTGTTCACGCCCTTTCGGGTGTGAGCGGAGCGGGAAGGAA
GCCAAAACAACAATTTCACTTCCCCGAAATGACGGAAAACTTCTTCAATTACGCGGTAGAAAAGCACAGGCACACTCCCG
AGATGGAAGACGTAATAAGGAGAGTTTACGGAAGAGAAGTAAAGGTAAGGTTTACTCCCACCGTAGTTCCTACCTCAAGG
GGAATGATATCCACGGTTTACCTGAAATCAGAAAAATTAAACGTAAAGGAGCTTTTCAAGGAAGTTTACGAAGACGAGAT
TTTCGTAAAGGTTGTGGACGAACCACCTCAAACCAAGTGGGTTCTGGGAACCAATTACTGTTTTATTTATCCCCATTACG
ACGAAAGGACAGGCTATTACGTTATTATTTCTGCAATTGACAACTTGGGTAAAGGAGCTTCTCTACAGGCGGTTCAAAAC
GCAAATTTAATGTTCGGGCTTGCGGAAGACGACGGGCTCCTTCAACTTCCCGTTTTCCCCTGA

Upstream 100 bases:

>100_bases
ACCTGAGACCCACCCTTAAAAAGGCAGGACTCCTTACGAGAGACGCAAGAGAGAAGGAAAGGAAGAAGTACGGTCAAATG
GGTGCAAGAGCCAAGTACAG

Downstream 100 bases:

>100_bases
AAGTTTGTTATACTAATTCTCCAAATGCGCGTTAAGGTGGACAGGGAGGAGCTTGAAGAGGTTCTTAAAAAAGCAAGAGA
AAGCACGGAAAAAAAAGCCG

Product: N-acetyl-gamma-glutamylphosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEIEFLEEPVEDYELAFLCLPHE
VSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHEREDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAI
YPFLKERVGIESVIVHALSGVSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSR
GMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYYVIISAIDNLGKGASLQAVQN
ANLMFGLAEDDGLLQLPVFP

Sequences:

>Translated_340_residues
MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEIEFLEEPVEDYELAFLCLPHE
VSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHEREDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAI
YPFLKERVGIESVIVHALSGVSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSR
GMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYYVIISAIDNLGKGASLQAVQN
ANLMFGLAEDDGLLQLPVFP
>Mature_340_residues
MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEIEFLEEPVEDYELAFLCLPHE
VSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHEREDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAI
YPFLKERVGIESVIVHALSGVSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSR
GMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYYVIISAIDNLGKGASLQAVQN
ANLMFGLAEDDGLLQLPVFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=347, Percent_Identity=33.1412103746398, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320913, Length=340, Percent_Identity=31.7647058823529, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_AQUAE (O67724)

Other databases:

- EMBL:   AE000657
- PIR:   B70462
- RefSeq:   NP_214292.1
- ProteinModelPortal:   O67724
- GeneID:   1193531
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1879
- NMPDR:   fig|224324.1.peg.1307
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   O67724
- ProtClustDB:   CLSK2299858
- BioCyc:   AAEO224324:AQ_1879-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38958; Mature: 38958

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEI
CCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EFLEEPVEDYELAFLCLPHEVSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHE
HHHHCCHHHHCEEEEECCCCCCHHHHHHHHHCCCEEEECCCCEEECCCHHHHHHCCCCCH
REDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAIYPFLKERVGIESVIVHALSG
HHHHHHHHHHCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHC
VSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSR
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCEEECCCC
GMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYY
CCEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEECCEEEEEECCCCCCCEE
VIISAIDNLGKGASLQAVQNANLMFGLAEDDGLLQLPVFP
EEEEEHHCCCCCCCEEEECCCCEEEEEECCCCEEECCCCC
>Mature Secondary Structure
MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEI
CCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EFLEEPVEDYELAFLCLPHEVSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHE
HHHHCCHHHHCEEEEECCCCCCHHHHHHHHHCCCEEEECCCCEEECCCHHHHHHCCCCCH
REDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAIYPFLKERVGIESVIVHALSG
HHHHHHHHHHCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHC
VSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSR
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCEEECCCC
GMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYY
CCEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEECCEEEEEECCCCCCCEE
VIISAIDNLGKGASLQAVQNANLMFGLAEDDGLLQLPVFP
EEEEEHHCCCCCCCEEEECCCCEEEEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320