Click here to switch to the map view.

The map label for this gene is exbB

Identifier: 15606823

GI number: 15606823

Start: 1236751

End: 1237197

Strand: Direct

Name: exbB

Synonym: aq_1757

Alternate gene names: 15606823

Gene position: 1236751-1237197 (Clockwise)

Preceding gene: 15606822

Following gene: 15606827

Centisome position: 79.72

GC content: 43.18

Gene sequence:

>447_bases
TTGATGGAAGAGATAAAAGAACTTATAGACTATGGGATAATGGGAACGCTCCTTTTTATGAGCTTCGTAGCCCTCGCCGT
GGGAATAGAGAGGTACTTATCTATAAGGTCCACAAAAGTAGAAAACTTCAAAAGTAAGGCTCAGCTTGAAAAGGAACTTA
CAAAAAGGCTTTACATTATTGCCACTGTAGCGTCAAACGCCCCTTACGTGGGACTTCTCGGAACTGTTCTGGGAATCCTT
CTTACCTTTTACATCATAGGAGAAAAGGGGATTGTGAACACTAAAGAGATAATGGTCGGACTTGCCCTTGCCTTAAAAGC
TACGGCTCTTGGACTCATCGTTGCAATTCCATCAACCATTCTTTACAACTTTCTGGTGAGAAAGGTAAGGGAGAAGCTCC
TGGACTGGGAGGCTATTCACGGAGAGTGTTCTTCAAGCCATGAGTAA

Upstream 100 bases:

>100_bases
AAAAATCTTTAAATCACTTAAAGGAACTCATAGTAAGGGAAGCGGAAGAAGAGCTCGTGGAGTATTTGAAGGAAGTAAAG
ATTAAGAGAATGGAGATAGA

Downstream 100 bases:

>100_bases
ACACTTTTGAAGGTTTCGGGCTCTTCTATCTCGAATACCATCCACTCCCCTTTAGTTGGGTGGTAAAAGCCGAGGTGGTA
TGCGATAAGCATATTACACT

Product: biopolymer transport exbB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MMEEIKELIDYGIMGTLLFMSFVALAVGIERYLSIRSTKVENFKSKAQLEKELTKRLYIIATVASNAPYVGLLGTVLGIL
LTFYIIGEKGIVNTKEIMVGLALALKATALGLIVAIPSTILYNFLVRKVREKLLDWEAIHGECSSSHE

Sequences:

>Translated_148_residues
MMEEIKELIDYGIMGTLLFMSFVALAVGIERYLSIRSTKVENFKSKAQLEKELTKRLYIIATVASNAPYVGLLGTVLGIL
LTFYIIGEKGIVNTKEIMVGLALALKATALGLIVAIPSTILYNFLVRKVREKLLDWEAIHGECSSSHE
>Mature_148_residues
MMEEIKELIDYGIMGTLLFMSFVALAVGIERYLSIRSTKVENFKSKAQLEKELTKRLYIIATVASNAPYVGLLGTVLGIL
LTFYIIGEKGIVNTKEIMVGLALALKATALGLIVAIPSTILYNFLVRKVREKLLDWEAIHGECSSSHE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family

Homologues:

Organism=Escherichia coli, GI1789381, Length=70, Percent_Identity=41.4285714285714, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1786958, Length=95, Percent_Identity=34.7368421052632, Blast_Score=59, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EXBB_AQUAE (O67637)

Other databases:

- EMBL:   AE000657
- PIR:   C70451
- RefSeq:   NP_214203.1
- GeneID:   1193352
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1757
- NMPDR:   fig|224324.1.peg.1218
- HOGENOM:   HBG681852
- OMA:   MLTFYNM
- BioCyc:   AAEO224324:AQ_1757-MONOMER
- InterPro:   IPR002898
- InterPro:   IPR014172
- TIGRFAMs:   TIGR02805

Pfam domain/function: PF01618 MotA_ExbB

EC number: NA

Molecular weight: Translated: 16396; Mature: 16396

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdf15294)-; HASH(0xe427f88)-; HASH(0xe0b4f20)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEEIKELIDYGIMGTLLFMSFVALAVGIERYLSIRSTKVENFKSKAQLEKELTKRLYII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ATVASNAPYVGLLGTVLGILLTFYIIGEKGIVNTKEIMVGLALALKATALGLIVAIPSTI
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYNFLVRKVREKLLDWEAIHGECSSSHE
HHHHHHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure
MMEEIKELIDYGIMGTLLFMSFVALAVGIERYLSIRSTKVENFKSKAQLEKELTKRLYII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ATVASNAPYVGLLGTVLGILLTFYIIGEKGIVNTKEIMVGLALALKATALGLIVAIPSTI
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYNFLVRKVREKLLDWEAIHGECSSSHE
HHHHHHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9537320