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The map label for this gene is 15606808

Identifier: 15606808

GI number: 15606808

Start: 1220470

End: 1222146

Strand: Direct

Name: 15606808

Synonym: aq_1732

Alternate gene names: NA

Gene position: 1220470-1222146 (Clockwise)

Preceding gene: 15606807

Following gene: 15606809

Centisome position: 78.67

GC content: 46.15

Gene sequence:

>1677_bases
ATGGACGTTCTTAGTATTCTTTTAATCCTTGTTGCAGTTGGAGTAGGCATTTTTGTAGGAAGACAATTTTTGGGACAAAA
ACAAGCCCCTGCACCTACATATCAGCCAGTGCCCTCTCCTCAAATACTGGAAGAAGCCAAAAGTAAGGCGGAAGAGATAA
TAAAAGAGGCTAAAGAAAAGGCAGAAGTAATACTAAAAGAAGCTAAGGAAAGCGCGGAGAAGATAGTAAGGGAGGCGGAA
GAAAAGGCGGAGAAACTCATAAGGGAAGCTAAGGAAGAAGTTGAAAGGATAAAGGAGGAAGTAGAAAGGAGGAAGAAGGA
ATTAAAGGAGAGAGAGGAAAATGTACTCGCAAAAGAAAGACACCTGGACAGGAGATGGGAAGCCCTTGAGAAGAGGGAAG
AGGAACTCCTCCACAGGGAAAGGGAACTTAAGGATTTTGAAAGAAGTCTGGAAAGGTGGAGAGACGAAATAAGACACAAG
GAAGAAGAGCTAAAACACATGAAAGAGGAAGTGGAAGAACTAAAGAAAAAAGAACTTGAAGAACTCCAGAGGATAGCAAA
GCTCACTTTAGAAGAGGCAAGGCAGGAGATAATAAAGAAGGTTGAAGAAGAGGCGAAGAAGGACGCCGTAAAACTCATGA
AAGTCATAGAAGAAGACGCAAAGAGGAGGGCGGAGTTTGAAGCCAAGAAGATAATAGCGACCGCAACCCAGAGACTCGCT
CCCCAGATAGCGGTAAACTACACCACGACCACCGTAGAACTCCCCAGCAACGAGTTCAAGGGAAGGATAATAGGTAGGGA
AGGAAGGAACATAAGAACCTTTGAAATACTCACAGGTGTTGACCTCATAATAGACGACACTCCGGACATCGTGACTATAT
CTTCCTTTGACCCCTTAAGGAGAGAAATAGCAAAAGAAGCCCTCCAGAGGCTCATAGCGGACGGGAGAATTCACCCAGCG
AGGATTGAAGAAGTAGTTGATGAAGTAAAGAGGGAGTTTGACGAAAAGATAAGAAAAATTGGTGAAGAGACCGTTTACGA
GCTTGACCTTCACGACATAAACCCCGGACTCTACTACTACATAGGAAAGCTCTACTTCAGAACAAGCTATTCCCAGAACG
TCCTCTTACACTCCAAGGAAGTTGCCTATATAGCGGGACTAATGGCAGAAGAGCTCGGACTTGACGCAAAGCTCGCAAGG
AGAGCGGGACTCCTTCACGACATAGGAAAGGCTATTTCTCACGAACTCGGAGGTTCTCACACGGACATAGGCGTAGAGCT
TGCAAGGAAGTACGGAGAGCCCGACGCAGTAATAAACGCCATAAGGGCACACCACGAGGAAGAACCCGTAAGATATCCCG
AGGTTGCCCTCGTTTGTGCAGCGGATGCCCTTTCGGCTGCAAGACCGGGAGCCAGAAGGGAAACCCTTGAAGCTTACATA
AGGAGACTTGAGAAACTCGAAGAAATAGTGAAGTCCTTCAAGGGAGTAGCGAACGCATATGCAGTACAGGCGGGAAGGGA
AGTAAGAGTTATAGTAAATCCCGAGGAGATTTCTGACGAAGAGGCTTACTTGCTCAGTAAAGAAATACCCAAGAAGATAG
AAGAAGAACTGGACTTTCCCGGCCAGATAAAGGTGGTAGTGATAAGGGAGACGAGGCACGTGGAGTACGCCAAGTAA

Upstream 100 bases:

>100_bases
GTCGCCTACTCTTTTCAGGTATTTGAGCGTCTGCCCAGAGACGCTTGGGACATTCCCGTTGACGTTCTCGTCACAGAAAA
AAACGTAAGGAGGTTGAGAG

Downstream 100 bases:

>100_bases
TTTCCTTCCCTGTCGTTTTATACTCTTATAAGTAAGTTTTATTGAAAGATAAATTCCCGTGATAGAAATTAAGATCTCTG
ATGTCACAGGCGGTCAAAGA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MDVLSILLILVAVGVGIFVGRQFLGQKQAPAPTYQPVPSPQILEEAKSKAEEIIKEAKEKAEVILKEAKESAEKIVREAE
EKAEKLIREAKEEVERIKEEVERRKKELKEREENVLAKERHLDRRWEALEKREEELLHRERELKDFERSLERWRDEIRHK
EEELKHMKEEVEELKKKELEELQRIAKLTLEEARQEIIKKVEEEAKKDAVKLMKVIEEDAKRRAEFEAKKIIATATQRLA
PQIAVNYTTTTVELPSNEFKGRIIGREGRNIRTFEILTGVDLIIDDTPDIVTISSFDPLRREIAKEALQRLIADGRIHPA
RIEEVVDEVKREFDEKIRKIGEETVYELDLHDINPGLYYYIGKLYFRTSYSQNVLLHSKEVAYIAGLMAEELGLDAKLAR
RAGLLHDIGKAISHELGGSHTDIGVELARKYGEPDAVINAIRAHHEEEPVRYPEVALVCAADALSAARPGARRETLEAYI
RRLEKLEEIVKSFKGVANAYAVQAGREVRVIVNPEEISDEEAYLLSKEIPKKIEEELDFPGQIKVVVIRETRHVEYAK

Sequences:

>Translated_558_residues
MDVLSILLILVAVGVGIFVGRQFLGQKQAPAPTYQPVPSPQILEEAKSKAEEIIKEAKEKAEVILKEAKESAEKIVREAE
EKAEKLIREAKEEVERIKEEVERRKKELKEREENVLAKERHLDRRWEALEKREEELLHRERELKDFERSLERWRDEIRHK
EEELKHMKEEVEELKKKELEELQRIAKLTLEEARQEIIKKVEEEAKKDAVKLMKVIEEDAKRRAEFEAKKIIATATQRLA
PQIAVNYTTTTVELPSNEFKGRIIGREGRNIRTFEILTGVDLIIDDTPDIVTISSFDPLRREIAKEALQRLIADGRIHPA
RIEEVVDEVKREFDEKIRKIGEETVYELDLHDINPGLYYYIGKLYFRTSYSQNVLLHSKEVAYIAGLMAEELGLDAKLAR
RAGLLHDIGKAISHELGGSHTDIGVELARKYGEPDAVINAIRAHHEEEPVRYPEVALVCAADALSAARPGARRETLEAYI
RRLEKLEEIVKSFKGVANAYAVQAGREVRVIVNPEEISDEEAYLLSKEIPKKIEEELDFPGQIKVVVIRETRHVEYAK
>Mature_558_residues
MDVLSILLILVAVGVGIFVGRQFLGQKQAPAPTYQPVPSPQILEEAKSKAEEIIKEAKEKAEVILKEAKESAEKIVREAE
EKAEKLIREAKEEVERIKEEVERRKKELKEREENVLAKERHLDRRWEALEKREEELLHRERELKDFERSLERWRDEIRHK
EEELKHMKEEVEELKKKELEELQRIAKLTLEEARQEIIKKVEEEAKKDAVKLMKVIEEDAKRRAEFEAKKIIATATQRLA
PQIAVNYTTTTVELPSNEFKGRIIGREGRNIRTFEILTGVDLIIDDTPDIVTISSFDPLRREIAKEALQRLIADGRIHPA
RIEEVVDEVKREFDEKIRKIGEETVYELDLHDINPGLYYYIGKLYFRTSYSQNVLLHSKEVAYIAGLMAEELGLDAKLAR
RAGLLHDIGKAISHELGGSHTDIGVELARKYGEPDAVINAIRAHHEEEPVRYPEVALVCAADALSAARPGARRETLEAYI
RRLEKLEEIVKSFKGVANAYAVQAGREVRVIVNPEEISDEEAYLLSKEIPKKIEEELDFPGQIKVVVIRETRHVEYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_AQUAE (O67622)

Other databases:

- EMBL:   AE000657
- PIR:   D70449
- RefSeq:   NP_214188.1
- ProteinModelPortal:   O67622
- SMR:   O67622
- GeneID:   1193337
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1732
- NMPDR:   fig|224324.1.peg.1203
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   AAEO224324:AQ_1732-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 64330; Mature: 64330

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdc73ba4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLSILLILVAVGVGIFVGRQFLGQKQAPAPTYQPVPSPQILEEAKSKAEEIIKEAKEK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AEVILKEAKESAEKIVREAEEKAEKLIREAKEEVERIKEEVERRKKELKEREENVLAKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLDRRWEALEKREEELLHRERELKDFERSLERWRDEIRHKEEELKHMKEEVEELKKKELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELQRIAKLTLEEARQEIIKKVEEEAKKDAVKLMKVIEEDAKRRAEFEAKKIIATATQRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PQIAVNYTTTTVELPSNEFKGRIIGREGRNIRTFEILTGVDLIIDDTPDIVTISSFDPLR
CHHEEEEEEEEEECCCCCCCCCEECCCCCCEEEEEHHHCCEEEECCCCCEEEECCCCHHH
REIAKEALQRLIADGRIHPARIEEVVDEVKREFDEKIRKIGEETVYELDLHDINPGLYYY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
IGKLYFRTSYSQNVLLHSKEVAYIAGLMAEELGLDAKLARRAGLLHDIGKAISHELGGSH
HHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TDIGVELARKYGEPDAVINAIRAHHEEEPVRYPEVALVCAADALSAARPGARRETLEAYI
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
RRLEKLEEIVKSFKGVANAYAVQAGREVRVIVNPEEISDEEAYLLSKEIPKKIEEELDFP
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHCCCC
GQIKVVVIRETRHVEYAK
CCEEEEEEECCCCCCCCH
>Mature Secondary Structure
MDVLSILLILVAVGVGIFVGRQFLGQKQAPAPTYQPVPSPQILEEAKSKAEEIIKEAKEK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AEVILKEAKESAEKIVREAEEKAEKLIREAKEEVERIKEEVERRKKELKEREENVLAKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLDRRWEALEKREEELLHRERELKDFERSLERWRDEIRHKEEELKHMKEEVEELKKKELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELQRIAKLTLEEARQEIIKKVEEEAKKDAVKLMKVIEEDAKRRAEFEAKKIIATATQRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PQIAVNYTTTTVELPSNEFKGRIIGREGRNIRTFEILTGVDLIIDDTPDIVTISSFDPLR
CHHEEEEEEEEEECCCCCCCCCEECCCCCCEEEEEHHHCCEEEECCCCCEEEECCCCHHH
REIAKEALQRLIADGRIHPARIEEVVDEVKREFDEKIRKIGEETVYELDLHDINPGLYYY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
IGKLYFRTSYSQNVLLHSKEVAYIAGLMAEELGLDAKLARRAGLLHDIGKAISHELGGSH
HHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TDIGVELARKYGEPDAVINAIRAHHEEEPVRYPEVALVCAADALSAARPGARRETLEAYI
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
RRLEKLEEIVKSFKGVANAYAVQAGREVRVIVNPEEISDEEAYLLSKEIPKKIEEELDFP
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHCCCC
GQIKVVVIRETRHVEYAK
CCEEEEEEECCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320