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The map label for this gene is hslV

Identifier: 15606773

GI number: 15606773

Start: 1173775

End: 1174305

Strand: Direct

Name: hslV

Synonym: aq_1671

Alternate gene names: 15606773

Gene position: 1173775-1174305 (Clockwise)

Preceding gene: 15606772

Following gene: 15606775

Centisome position: 75.66

GC content: 49.15

Gene sequence:

>531_bases
ATGGAAGTGAAAGCTACAACTATACTCGCGGTGAGGAGAGACGGAAAGACGGCTGTAGGCGGAGACGGTCAGGTAACTCT
GGGAAGTTCTGTGATAAAACACACCGCGAGGAAGATAAGGAAACTTTACAAAGGGCAGGTGATAGTAGGCTTTGCGGGAA
GTGCAGCGGACGGACTGGCCCTGATGGAAAGGCTGGAAGCAAAACTCGAAGAGTACAGGGGAAACTTGCTAAAGGCTTCC
GTTCAGCTTGCAAAGGATTGGAGGATGGACAAGTACCTCAGAAGGCTGGAAGCACTACTCTTGGCGGTGGACAGGGAACA
CATGCTCCTTATATCTGGAAACGGGGACATAATAGAGCCGGATGAGCCCGTTCTCGCCATAGGTTCTGGGGGAGATTACG
CAAGGGCTGCAGCTCTTGCCCTTTACAGGAATACGGATCTTTCCGCCAGAGAGATAGTGGAGAAGTCTTTAAAGATAGCC
TCGGAGATATGTATATACACGAACGATAAATTCGTAATTGAAGAGATTTAA

Upstream 100 bases:

>100_bases
AAGGGCACTCCTCTTTCTGATGGAGGTTTACCATACCGTGGGAGAAGATCCGGTGAAGGCTCTGGGAAATAAACATCCGT
TCCTCGAGTAAAATGAACTT

Downstream 100 bases:

>100_bases
TTTTATCGGGGCGACCGGACTCGAACCGGCGACCTCTGGCTCCCGAAGCCAGCGCGCTACCACCTGCGCTACGCCCCGTT
GAGTATAAAAAATTATAAAA

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MEVKATTILAVRRDGKTAVGGDGQVTLGSSVIKHTARKIRKLYKGQVIVGFAGSAADGLALMERLEAKLEEYRGNLLKAS
VQLAKDWRMDKYLRRLEALLLAVDREHMLLISGNGDIIEPDEPVLAIGSGGDYARAAALALYRNTDLSAREIVEKSLKIA
SEICIYTNDKFVIEEI

Sequences:

>Translated_176_residues
MEVKATTILAVRRDGKTAVGGDGQVTLGSSVIKHTARKIRKLYKGQVIVGFAGSAADGLALMERLEAKLEEYRGNLLKAS
VQLAKDWRMDKYLRRLEALLLAVDREHMLLISGNGDIIEPDEPVLAIGSGGDYARAAALALYRNTDLSAREIVEKSLKIA
SEICIYTNDKFVIEEI
>Mature_176_residues
MEVKATTILAVRRDGKTAVGGDGQVTLGSSVIKHTARKIRKLYKGQVIVGFAGSAADGLALMERLEAKLEEYRGNLLKAS
VQLAKDWRMDKYLRRLEALLLAVDREHMLLISGNGDIIEPDEPVLAIGSGGDYARAAALALYRNTDLSAREIVEKSLKIA
SEICIYTNDKFVIEEI

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=56.140350877193, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_AQUAE (O67587)

Other databases:

- EMBL:   AE000657
- PIR:   B70445
- RefSeq:   NP_214153.1
- ProteinModelPortal:   O67587
- SMR:   O67587
- GeneID:   1193303
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1671
- NMPDR:   fig|224324.1.peg.1168
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   O67587
- ProtClustDB:   PRK05456
- BioCyc:   AAEO224324:AQ_1671-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19289; Mature: 19289

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: ACT_SITE 6-6

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKATTILAVRRDGKTAVGGDGQVTLGSSVIKHTARKIRKLYKGQVIVGFAGSAADGLA
CCCCEEEEEEEECCCCEEECCCCCEEECHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
LMERLEAKLEEYRGNLLKASVQLAKDWRMDKYLRRLEALLLAVDREHMLLISGNGDIIEP
HHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEECC
DEPVLAIGSGGDYARAAALALYRNTDLSAREIVEKSLKIASEICIYTNDKFVIEEI
CCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCEEEEEEC
>Mature Secondary Structure
MEVKATTILAVRRDGKTAVGGDGQVTLGSSVIKHTARKIRKLYKGQVIVGFAGSAADGLA
CCCCEEEEEEEECCCCEEECCCCCEEECHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
LMERLEAKLEEYRGNLLKASVQLAKDWRMDKYLRRLEALLLAVDREHMLLISGNGDIIEP
HHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEECC
DEPVLAIGSGGDYARAAALALYRNTDLSAREIVEKSLKIASEICIYTNDKFVIEEI
CCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320