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The map label for this gene is pycA [H]

Identifier: 15606669

GI number: 15606669

Start: 1079955

End: 1081922

Strand: Direct

Name: pycA [H]

Synonym: aq_1520

Alternate gene names: 15606669

Gene position: 1079955-1081922 (Clockwise)

Preceding gene: 15606668

Following gene: 15606670

Centisome position: 69.61

GC content: 47.1

Gene sequence:

>1968_bases
ATGGTAGTAAACCCGGAGGTTATAGAAGAAGTCAAGGAGAAAATTAAGGAAGTTAAGAATAAGGGCTTTAAGAAGAAGAT
ATTAATTACCGACCTCACGCCAAGAGACGGACAGCAGTGCAAACTCGCTACCCGTGTGAGAACCGAGGACCTCCTCCCCT
TATGCGAAGCCTTAGACAAGTGCGGATTTTACGCGGTAGAAGTCTGGGGAGGAGCTACGTACGACGTTTGCCTGAGATAC
CTCAAAGAGGACCCATGGGAAAGGCTAAGGAGAATAAAGGAAGTAATGCCCAACACCAAACTCCAGATGCTCTTCAGGGG
ACAGAACATAGTCGGTTACAAACCCAGAAGCGACTATGTAGTTAAGAAGTTCGTTGAAAAGGCTATAGAAAATGGAATAA
CCGTTTTCAGAGTGTTTGACTCTCTCAACGACAACAGGAATATAGAAACCGCTGTTAAAGCTATAAAGGAATTCGGCGGA
GAAGTTCACGCTGAAATCTCCTACACCAGAAGTCCCATACACACTTACGAGCTCTGGATGAGGTATGCTCAGGAACTGGC
GGAAATGGAACCCGACTGGATATCCTTTAAGGATGCAACGGGGATAATGCAACCCTTTGAATGTTACCAGATAATCAAGG
GAATAAAGGAAGTAACGGGAGGAAAGATACCAGTTCTCCTTCACAACCACGACATGAGCGGAATGGCGACCATGAACCAC
ATAATGGCTGTTCTCGCAGGCGTCGATATGCTGGACACAGTACTTTCACCCTTAGCGTTCGGTTCATCTCACCCTGCAAC
CGAGACCATAATCGCAGCGCTTGAAGGAACACCTTACGACACGGGACTTGACCTTCAAAAGGTTTCGGAAGCTGCGGAAA
TAGCTAAGAAGATTAAGAAGAAGTACAAGAAGTATGAAACGGAATACGCGGGAGTTAACGCAAAAGTTCTCATACACAAG
ATACCCGGTGGAATGATATCCAACATGGTTGCACAACTGATGGAGGCAAACGCACTCGACAAGATAGAAGAAGCACTAGA
AGAAGTTCCGAGAGTAGAAAAAGACCTTGGATACCCACCGTTGCTAACACCTTCTTCACAAATAGTCGGTGTTCAGGCGG
TTCTGAACGTAATCACGGGAGAAAGGTACAAAGTAATCACAAAAGAAGTGAGAGATTACGTAGAAGGAAAGTATGGAAGA
CCGCCCGGACCAATATCCAAGGAACTCGTTGAAAAGATACTCGGTCCCGGAAAAGAACCGGACTTCTCCAAGAGGGCTGC
CGACTACGCCGATCCCCACGAATGGGACAAGGCTAAGAAGGAACTCGAAGAGCTCTTCAAAAGAGAACCCACAGACGAAG
AAGTACTCCTCTACATACTCTTCCCCATGCAGGCAAAAGAGTTCTTTGAACTCAGGGAAAAGGGAGAACTCCATCCAGAA
CCCGTGGAAGCGGAACTCCCGGAAGTTGCAGAAACGAAGCCCGGAGAAGTTCCCGGCGCTGCACCCGTAGAGTTTGAACT
CACATACCACGGTGAGAAGTTCAAGGTAAGGATAGAAGGCGTTTCCGTGGACGCAGAAAGCGGAAAACCCAGGAAGTACT
ACGTAAGGATAAACAACAGACTTGAAGAAATACAGTTAAAGCCTTTTAAGGAAGCGATACCCCAGGGTGGCGGTGCCCAA
ACAGTTCAGAGTGCGGAAGAAGAAGAGGGAATTCCCAAGGCTACGGAACCCGGAGACGTTACACCGCCCATGCCCGGTAA
GGTTGTGAAGATACTCGTAAAAGAAGGAGAACCTGTTCAGCAGGGACAAACCGTTGCAACCGTTGAAGCAATGAAGATGG
AAAACGAAGTCCATGCACCCATAGACGGAATAGTTAAGAAGATATTCGCAAAACCCGGAGACCAAGTTAACCCAGATCAA
GCGATAATGAGAATAGTCCCCCACAAAGAAGATAAGAGCTATCAATAA

Upstream 100 bases:

>100_bases
AGTACGAAGAACACAAGGACAAGGAGGATTTTGCGGCACTAATTTCTGCGGCTATAGCCGCTTACCACGGTTTATAAAAA
CTTTAAAGGAGGTAATATAG

Downstream 100 bases:

>100_bases
GCTTTCCTTTTTCCCTTCTTTTTCTTTTAAAATTTTTAAAATGGAGTATTGCAGAGATTTATCTGAAAAACTCAGGGAAG
TTATTAGAAAGGAAACTGTA

Product: pyruvate carboxylase subunit B

Products: NA

Alternate protein names: 2-oxoglutarate carboxylase alpha subunit [H]

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MVVNPEVIEEVKEKIKEVKNKGFKKKILITDLTPRDGQQCKLATRVRTEDLLPLCEALDKCGFYAVEVWGGATYDVCLRY
LKEDPWERLRRIKEVMPNTKLQMLFRGQNIVGYKPRSDYVVKKFVEKAIENGITVFRVFDSLNDNRNIETAVKAIKEFGG
EVHAEISYTRSPIHTYELWMRYAQELAEMEPDWISFKDATGIMQPFECYQIIKGIKEVTGGKIPVLLHNHDMSGMATMNH
IMAVLAGVDMLDTVLSPLAFGSSHPATETIIAALEGTPYDTGLDLQKVSEAAEIAKKIKKKYKKYETEYAGVNAKVLIHK
IPGGMISNMVAQLMEANALDKIEEALEEVPRVEKDLGYPPLLTPSSQIVGVQAVLNVITGERYKVITKEVRDYVEGKYGR
PPGPISKELVEKILGPGKEPDFSKRAADYADPHEWDKAKKELEELFKREPTDEEVLLYILFPMQAKEFFELREKGELHPE
PVEAELPEVAETKPGEVPGAAPVEFELTYHGEKFKVRIEGVSVDAESGKPRKYYVRINNRLEEIQLKPFKEAIPQGGGAQ
TVQSAEEEEGIPKATEPGDVTPPMPGKVVKILVKEGEPVQQGQTVATVEAMKMENEVHAPIDGIVKKIFAKPGDQVNPDQ
AIMRIVPHKEDKSYQ

Sequences:

>Translated_655_residues
MVVNPEVIEEVKEKIKEVKNKGFKKKILITDLTPRDGQQCKLATRVRTEDLLPLCEALDKCGFYAVEVWGGATYDVCLRY
LKEDPWERLRRIKEVMPNTKLQMLFRGQNIVGYKPRSDYVVKKFVEKAIENGITVFRVFDSLNDNRNIETAVKAIKEFGG
EVHAEISYTRSPIHTYELWMRYAQELAEMEPDWISFKDATGIMQPFECYQIIKGIKEVTGGKIPVLLHNHDMSGMATMNH
IMAVLAGVDMLDTVLSPLAFGSSHPATETIIAALEGTPYDTGLDLQKVSEAAEIAKKIKKKYKKYETEYAGVNAKVLIHK
IPGGMISNMVAQLMEANALDKIEEALEEVPRVEKDLGYPPLLTPSSQIVGVQAVLNVITGERYKVITKEVRDYVEGKYGR
PPGPISKELVEKILGPGKEPDFSKRAADYADPHEWDKAKKELEELFKREPTDEEVLLYILFPMQAKEFFELREKGELHPE
PVEAELPEVAETKPGEVPGAAPVEFELTYHGEKFKVRIEGVSVDAESGKPRKYYVRINNRLEEIQLKPFKEAIPQGGGAQ
TVQSAEEEEGIPKATEPGDVTPPMPGKVVKILVKEGEPVQQGQTVATVEAMKMENEVHAPIDGIVKKIFAKPGDQVNPDQ
AIMRIVPHKEDKSYQ
>Mature_655_residues
MVVNPEVIEEVKEKIKEVKNKGFKKKILITDLTPRDGQQCKLATRVRTEDLLPLCEALDKCGFYAVEVWGGATYDVCLRY
LKEDPWERLRRIKEVMPNTKLQMLFRGQNIVGYKPRSDYVVKKFVEKAIENGITVFRVFDSLNDNRNIETAVKAIKEFGG
EVHAEISYTRSPIHTYELWMRYAQELAEMEPDWISFKDATGIMQPFECYQIIKGIKEVTGGKIPVLLHNHDMSGMATMNH
IMAVLAGVDMLDTVLSPLAFGSSHPATETIIAALEGTPYDTGLDLQKVSEAAEIAKKIKKKYKKYETEYAGVNAKVLIHK
IPGGMISNMVAQLMEANALDKIEEALEEVPRVEKDLGYPPLLTPSSQIVGVQAVLNVITGERYKVITKEVRDYVEGKYGR
PPGPISKELVEKILGPGKEPDFSKRAADYADPHEWDKAKKELEELFKREPTDEEVLLYILFPMQAKEFFELREKGELHPE
PVEAELPEVAETKPGEVPGAAPVEFELTYHGEKFKVRIEGVSVDAESGKPRKYYVRINNRLEEIQLKPFKEAIPQGGGAQ
TVQSAEEEEGIPKATEPGDVTPPMPGKVVKILVKEGEPVQQGQTVATVEAMKMENEVHAPIDGIVKKIFAKPGDQVNPDQ
AIMRIVPHKEDKSYQ

Specific function: Unknown

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=645, Percent_Identity=30.5426356589147, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI106049295, Length=645, Percent_Identity=30.5426356589147, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI106049292, Length=645, Percent_Identity=30.5426356589147, Blast_Score=257, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17562816, Length=657, Percent_Identity=32.2678843226788, Blast_Score=285, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6319695, Length=636, Percent_Identity=29.874213836478, Blast_Score=282, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6321376, Length=633, Percent_Identity=28.1200631911532, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI281363050, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652224, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652222, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652220, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652218, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652212, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652210, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652214, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI19921944, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24652216, Length=654, Percent_Identity=33.4862385321101, Blast_Score=294, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.7 [H]

Molecular weight: Translated: 73614; Mature: 73614

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVNPEVIEEVKEKIKEVKNKGFKKKILITDLTPRDGQQCKLATRVRTEDLLPLCEALDK
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHCHHHHHHHHHHHHH
CGFYAVEVWGGATYDVCLRYLKEDPWERLRRIKEVMPNTKLQMLFRGQNIVGYKPRSDYV
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCCHHH
VKKFVEKAIENGITVFRVFDSLNDNRNIETAVKAIKEFGGEVHAEISYTRSPIHTYELWM
HHHHHHHHHHCCCEEEEEHHHCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHH
RYAQELAEMEPDWISFKDATGIMQPFECYQIIKGIKEVTGGKIPVLLHNHDMSGMATMNH
HHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
IMAVLAGVDMLDTVLSPLAFGSSHPATETIIAALEGTPYDTGLDLQKVSEAAEIAKKIKK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
KYKKYETEYAGVNAKVLIHKIPGGMISNMVAQLMEANALDKIEEALEEVPRVEKDLGYPP
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCCCC
LLTPSSQIVGVQAVLNVITGERYKVITKEVRDYVEGKYGRPPGPISKELVEKILGPGKEP
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
DFSKRAADYADPHEWDKAKKELEELFKREPTDEEVLLYILFPMQAKEFFELREKGELHPE
CHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCC
PVEAELPEVAETKPGEVPGAAPVEFELTYHGEKFKVRIEGVSVDAESGKPRKYYVRINNR
CCCCCCCHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEEECCCCCCEEEEEEECCC
LEEIQLKPFKEAIPQGGGAQTVQSAEEEEGIPKATEPGDVTPPMPGKVVKILVKEGEPVQ
HHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHH
QGQTVATVEAMKMENEVHAPIDGIVKKIFAKPGDQVNPDQAIMRIVPHKEDKSYQ
CCCEEHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVVNPEVIEEVKEKIKEVKNKGFKKKILITDLTPRDGQQCKLATRVRTEDLLPLCEALDK
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHCHHHHHHHHHHHHH
CGFYAVEVWGGATYDVCLRYLKEDPWERLRRIKEVMPNTKLQMLFRGQNIVGYKPRSDYV
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCCHHH
VKKFVEKAIENGITVFRVFDSLNDNRNIETAVKAIKEFGGEVHAEISYTRSPIHTYELWM
HHHHHHHHHHCCCEEEEEHHHCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHH
RYAQELAEMEPDWISFKDATGIMQPFECYQIIKGIKEVTGGKIPVLLHNHDMSGMATMNH
HHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
IMAVLAGVDMLDTVLSPLAFGSSHPATETIIAALEGTPYDTGLDLQKVSEAAEIAKKIKK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
KYKKYETEYAGVNAKVLIHKIPGGMISNMVAQLMEANALDKIEEALEEVPRVEKDLGYPP
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCCCC
LLTPSSQIVGVQAVLNVITGERYKVITKEVRDYVEGKYGRPPGPISKELVEKILGPGKEP
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
DFSKRAADYADPHEWDKAKKELEELFKREPTDEEVLLYILFPMQAKEFFELREKGELHPE
CHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCC
PVEAELPEVAETKPGEVPGAAPVEFELTYHGEKFKVRIEGVSVDAESGKPRKYYVRINNR
CCCCCCCHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEEECCCCCCEEEEEEECCC
LEEIQLKPFKEAIPQGGGAQTVQSAEEEEGIPKATEPGDVTPPMPGKVVKILVKEGEPVQ
HHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHH
QGQTVATVEAMKMENEVHAPIDGIVKKIFAKPGDQVNPDQAIMRIVPHKEDKSYQ
CCCEEHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA