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The map label for this gene is mat

Identifier: 15606459

GI number: 15606459

Start: 863160

End: 864362

Strand: Direct

Name: mat

Synonym: aq_1226

Alternate gene names: 15606459

Gene position: 863160-864362 (Clockwise)

Preceding gene: 15606458

Following gene: 15606460

Centisome position: 55.64

GC content: 47.22

Gene sequence:

>1203_bases
TTGAAAAACATAGTAGTTACCCCCATGACCTTTGAACCCGTTTACGAGCAAGATGCGGAAATTGTTGAAAGAAAAGGCAT
AGGTCACCCGGACACCATATGCGACTATCTGGCGGAAGAGCTCTCCGTTGCGCTTTCAAAACTTTACATAGAGAGATTCG
GGGCTATTATGCACCACAACGTGGATAAAGCCCTTCTGGTAGGTGGTGAGGCGAATCCCGTTTTCGGCGGAGGAGAGGTA
ATATCCCCCATAGAGATATACCTCGTAGGAAGAGCTCTCAAGGAGTACAAGGGGGTAACGATTCCCGCAGAAGAGCTCGC
GATAGAAGTGGCAAGGGAGTGGCTGAAAGATAACATAAGGAACCTTGATCCTGACACACACGTGATAATAAAGCCAAGGA
TTAAGCCCGGAAGCAAGGACCTGGTGGACCTTTTTCTGAGATTTCAACAAAAGGGAGAGGTTCCCCTAGCCAACGATACC
TCCTTTGGAGTAGGCTTTGCACCCCTTGACGACCTAGAGAGAATAGTCTTCGAAACGGAACAGCTCCTTAACTCTCCTTC
CTTTAAAGAAAATCACCCTTACGTCGGAGAAGACATAAAGGTAATGGGAGTGAGGATAAAGGATAAGGTCAGGATTACGA
TAGCTTGTGCCTTCGTTAGCAAGTACGTTGAAAACATTCAGGATTACCTGGAAAAGAAAGAGCACGTAAGAAGAATAGTT
GAGGAAATGGCACAGGGTTTGACGCAGAGACAGGTAGAAGTTTTCATAAACACCGCGGACGATCCTGAAAGGGAAAGCGT
CTACATAACCGTTACCGGAACCTCTGCGGAACAGGGAGACGACGGACAGGTGGGAAGGGGAAACAGAGTAAACGGACTCA
TTACTCCTTACAGACCCATGAGCCTGGAAGCCGCGGCGGGTAAGAACCCCGTTTCCCATATAGGGAAGATTTACAACGTC
GTTGCCAATGTGATAGCGGACAGGGTAGTGAGTGAAATAGAAGAGGTTGAAGAAGCGTACTGCTACCTTGTTTCCCAGAT
AGGAAAACCTATAAACGAACCGCAGGTGTGTGACGTAAAGGTTAGAACGAAGAAAGATTTAAAGAGCCTTGAAGAGGAAA
TAAAGAGGATCGCTCAGGAAGAACTCGAAAAGATGCCCGAAACTTGGAAGAAGTTCCTCAACAGGGAGTATGCGGTAGCC
TAA

Upstream 100 bases:

>100_bases
CCTTTTACGACGGAGACGTGCTTTTGGGCGGAGGGATAATTGAAGAAAGCGTAAAGTGAGGTTATACTATTTAGCTTGAA
TCCTTTGAGGAGGTAAGGGA

Downstream 100 bases:

>100_bases
GGTAAGGTTAATACTATCTAACGTGTAAAATATTCTTTATGCTTACTAAGGAAGAAAAAAAGGTAGTTAGCGGAATAACC
TTCGTCGTAGTTGCCCGCTT

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKNIVVTPMTFEPVYEQDAEIVERKGIGHPDTICDYLAEELSVALSKLYIERFGAIMHHNVDKALLVGGEANPVFGGGEV
ISPIEIYLVGRALKEYKGVTIPAEELAIEVAREWLKDNIRNLDPDTHVIIKPRIKPGSKDLVDLFLRFQQKGEVPLANDT
SFGVGFAPLDDLERIVFETEQLLNSPSFKENHPYVGEDIKVMGVRIKDKVRITIACAFVSKYVENIQDYLEKKEHVRRIV
EEMAQGLTQRQVEVFINTADDPERESVYITVTGTSAEQGDDGQVGRGNRVNGLITPYRPMSLEAAAGKNPVSHIGKIYNV
VANVIADRVVSEIEEVEEAYCYLVSQIGKPINEPQVCDVKVRTKKDLKSLEEEIKRIAQEELEKMPETWKKFLNREYAVA

Sequences:

>Translated_400_residues
MKNIVVTPMTFEPVYEQDAEIVERKGIGHPDTICDYLAEELSVALSKLYIERFGAIMHHNVDKALLVGGEANPVFGGGEV
ISPIEIYLVGRALKEYKGVTIPAEELAIEVAREWLKDNIRNLDPDTHVIIKPRIKPGSKDLVDLFLRFQQKGEVPLANDT
SFGVGFAPLDDLERIVFETEQLLNSPSFKENHPYVGEDIKVMGVRIKDKVRITIACAFVSKYVENIQDYLEKKEHVRRIV
EEMAQGLTQRQVEVFINTADDPERESVYITVTGTSAEQGDDGQVGRGNRVNGLITPYRPMSLEAAAGKNPVSHIGKIYNV
VANVIADRVVSEIEEVEEAYCYLVSQIGKPINEPQVCDVKVRTKKDLKSLEEEIKRIAQEELEKMPETWKKFLNREYAVA
>Mature_400_residues
MKNIVVTPMTFEPVYEQDAEIVERKGIGHPDTICDYLAEELSVALSKLYIERFGAIMHHNVDKALLVGGEANPVFGGGEV
ISPIEIYLVGRALKEYKGVTIPAEELAIEVAREWLKDNIRNLDPDTHVIIKPRIKPGSKDLVDLFLRFQQKGEVPLANDT
SFGVGFAPLDDLERIVFETEQLLNSPSFKENHPYVGEDIKVMGVRIKDKVRITIACAFVSKYVENIQDYLEKKEHVRRIV
EEMAQGLTQRQVEVFINTADDPERESVYITVTGTSAEQGDDGQVGRGNRVNGLITPYRPMSLEAAAGKNPVSHIGKIYNV
VANVIADRVVSEIEEVEEAYCYLVSQIGKPINEPQVCDVKVRTKKDLKSLEEEIKRIAQEELEKMPETWKKFLNREYAVA

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METL_AQUAE (O67275)

Other databases:

- EMBL:   AE000657
- PIR:   H70405
- RefSeq:   NP_213839.1
- GeneID:   1192621
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1226
- NMPDR:   fig|224324.1.peg.854
- HOGENOM:   HBG297280
- OMA:   RPMSMEA
- ProtClustDB:   PRK04439
- BioCyc:   AAEO224324:AQ_1226-MONOMER
- BRENDA:   2.5.1.6
- HAMAP:   MF_00136
- InterPro:   IPR002795
- ProDom:   PD011777

Pfam domain/function: PF01941 AdoMet_Synthase

EC number: =2.5.1.6

Molecular weight: Translated: 45040; Mature: 45040

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIVVTPMTFEPVYEQDAEIVERKGIGHPDTICDYLAEELSVALSKLYIERFGAIMHHN
CCCEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VDKALLVGGEANPVFGGGEVISPIEIYLVGRALKEYKGVTIPAEELAIEVAREWLKDNIR
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
NLDPDTHVIIKPRIKPGSKDLVDLFLRFQQKGEVPLANDTSFGVGFAPLDDLERIVFETE
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QLLNSPSFKENHPYVGEDIKVMGVRIKDKVRITIACAFVSKYVENIQDYLEKKEHVRRIV
HHHCCCCCCCCCCCCCCCEEEEEEEEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EEMAQGLTQRQVEVFINTADDPERESVYITVTGTSAEQGDDGQVGRGNRVNGLITPYRPM
HHHHHHHHHHEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCC
SLEAAAGKNPVSHIGKIYNVVANVIADRVVSEIEEVEEAYCYLVSQIGKPINEPQVCDVK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VRTKKDLKSLEEEIKRIAQEELEKMPETWKKFLNREYAVA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNIVVTPMTFEPVYEQDAEIVERKGIGHPDTICDYLAEELSVALSKLYIERFGAIMHHN
CCCEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VDKALLVGGEANPVFGGGEVISPIEIYLVGRALKEYKGVTIPAEELAIEVAREWLKDNIR
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
NLDPDTHVIIKPRIKPGSKDLVDLFLRFQQKGEVPLANDTSFGVGFAPLDDLERIVFETE
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QLLNSPSFKENHPYVGEDIKVMGVRIKDKVRITIACAFVSKYVENIQDYLEKKEHVRRIV
HHHCCCCCCCCCCCCCCCEEEEEEEEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EEMAQGLTQRQVEVFINTADDPERESVYITVTGTSAEQGDDGQVGRGNRVNGLITPYRPM
HHHHHHHHHHEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCC
SLEAAAGKNPVSHIGKIYNVVANVIADRVVSEIEEVEEAYCYLVSQIGKPINEPQVCDVK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VRTKKDLKSLEEEIKRIAQEELEKMPETWKKFLNREYAVA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320