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The map label for this gene is topG1 [H]

Identifier: 15606410

GI number: 15606410

Start: 814948

End: 818481

Strand: Direct

Name: topG1 [H]

Synonym: aq_1159

Alternate gene names: 15606410

Gene position: 814948-818481 (Clockwise)

Preceding gene: 15606406

Following gene: 15606411

Centisome position: 52.53

GC content: 44.74

Gene sequence:

>3534_bases
TTGTTCATAAAAAAGAAAAGCAAAAGGTTTCCATCTAAAAGTTATCCTATTATTATGGCGTTAGAACTAATAGAAAGAGG
ATGTCCTAACTGCGGAGGGGTTATAAGTTCGGACAGGCTCGAAAAAGGCTTGCCCTGTTCAAAGTGCCTTCCAAAACCAA
CGGAAGAAAAAGTGTGCGATGCCCTTGAAGAACTGAAAACGCTAAAGTACTTAAAACCTTTCTGCGATACGGATAAAAGT
CTTGAAAGATTTATAAATTTCTTCGAAAAGGCTGTAGGTGCAAAGCCCTGGAGCCTCCAGAGGGTTTGGGCAAAGCGCGT
TTTTATGAACCAGTCCTTTGCGATAGTAGCTCCAACTGGAGTCGGTAAAACCACCTTCGGACTCGTTATGTCTCTGTTCT
TAAAGGGAAGAGTTTTGGCAATCTTCCCCACAAGGCTCCTCGCCCAGCAGGCGGGAGACAGACTCTCGGAGCTCGCCCAG
AAGGTTGGAGTTAACAAAAAAATTCTCATTTACCAATCAAAGAAAAACATAAGGGAACAATTCCTTAACGGTGATTGGGA
CATACTCCTCGGGACAAATATGTTCCTCCACAAGAACTTTGAAAACTTAATTAACTTTAAGTTCAAATTAATCTTCATAG
ACGACATAGACAGCTTTCTCAAGAGAGGTAAAAACGTAGATTACCTCTTTAAACTTCTCGGCTTTTCCGGCGAGGAGATA
AAGCTCGCCCTCAAGGAAAACAAGACCCAGAGGGATTATGACAGGCTTGCAAGGATAAGAAAGAGAAAGAGGGATACGGT
TCTCATCGTTTCTTCCGCCACCCTCAAACCTAGGGGAAAGAGGGCATACCTCTTCCGAAATTTACTCGGTTTTGACGTCC
AGAAAGCTATAACAACGTTAAGGAACATAGTGGACGTTGCGGAGCCCGTAAAGGATCTCGAGGAAGCTCTGGAAAAATCC
GTGGAACTTATAAAGAAACTCGGGAAAGGGGGACTCGTTTACCTTTCTGTCTTTTACGGAAAAGACAAAGTTCAAGAAGT
AAAAGAGTTTTATAGAAAGCACGGTATAAACGCTGTATCTTACTTGGACTACAAACCCGAGGAGCTTTATCAGATCCTCG
AAAAGGGCGAGTTTGACGTTGCGGTAGGAATTTCCCACATAACGAACCCCTTAGTTCGTGGAATAGACCTTCCCCACATA
ATAAGGTACGCGGTCTTTTTAGACCCCCCGAAGCACGTATTCCCGACGGAACTTACTTTAAGCCCCCCACTCCTCCACGG
ACTGCTTCTTACGCTTCTCAACCTCTTTGAAGGAGACGACAGATTAAAGGCCATACAGTACGTTATGTACTTGAAAAGGT
ACCTCACCCTCAGAGAAGAACAACTCGACAACTACCCGAGGATAAAGGAAAGAGTGGAGGAGATAAAGAACTTCCTTGAG
AATTACTTAAAAGACGAGAACTTCCTTAAGAAGATAAAAGAGAGTGAAGACATCTCCCTAGTTCCTAAGGAGGGAAAGCT
TTATATAGTCGTGGGAGACGCAAACTCCTACATTCAGGCGAGCGGAAGAACCTCAAGGTTTATAGCAGGAGGAATGACGA
AAGGACTTTCCGTGGTTTACTACTCCGACCCGAAGGCCTTTTACTCTCTCAAAAAACGCCTTGCCCTTTATTACATGACA
CAGGAAATAGAGTTCAAACGATTAAGCGAAGTAGACCTAAATAAATTAATAAAGGAAATAGACGAGGACAGAAAGAGGGC
AAGGGAAATCCTTCAAGGAAAAGGTGTAGCTCAGATAAAGGACCTCTTCAAAACCACCCTCGTTATCGTTGAAAGCCCAA
ACAAGGCGAGAACGATAGCGGGCTTTTTCGGAAAACCCCAGATGAGACTCGTGGAAGACTCCGTCGCCTACGAAGTTCCC
TTGGGAGACAGACTCCTCGTCATAACCGCCTCCCTCGGACACGTTCTTGACCTCGTAACCGATAAAGGATTTTTCGGTGT
CCTTGACGACACGTACCCCTACCTTCCCGTGTACGACACTATAAAGATATGCAGGGAAACACACGAACAGCACACTGAAT
ACGAGTACCTAAAGAAACGCTGTAAGGGAAAAATAGAGGACAAGCTGGAAATAATAAAGGGAGTTAGGGAAGTTTCTTAC
GAAGTAGATGAAGTCTTTATAGCAACGGACCCTGACGCGGAAGGGGAAAAGATAGGTTACGACCTGTACCTCCTCTCAAA
GCCCTTTAACTTCAACATAAAGAGGGCGGAATTCCACGAAGTCACGCCGAAGGCCTTTAGAGAAGCCATACAAAACCCCA
GAGAAGTTGACCTGAACCTCGTAAAAGCACAGCTCGTGAGGAGAATTCTCGACAGGTGGGTGGGCTTTACGCTTTCCCAC
ATCCTCTGGGACGCCTTCGGTAAAAAGTGGCTCTCCGCGGGAAGAGTCCAGACACCGGTTCTCGGCTGGGTAATAAAACG
CTACGAAGAGTCAAAGGAAAAGAAGGGAGAAATCCTCCTTCACGTAAACGACTTCCCTTTAAAGATAGAAATTGAGGACC
TGATGTTCGCAAAAGAAATTTTCAAGGACCTTGAACTGGCGGATATATCCCTCTCAAACCCTCAGGAAGAGGAAAAAAGA
CCGCTTCCTCCTTATACGACAGACACGGTTCTGGAAGACGCAAACGAGAAACTCCACCTTTCCGCTCACAAAACGATGAA
AATACTTCAGGAACTCTTTGAAGCGGGCTACATAACCTACCACAGAACGGACTCCACCCGCGTATCGGATGCGGGAAAGT
ATTTAGTTGCAAAACCTTACATAACGAAGATGTTCGGAGAAGAGTACTTCTACCCGAGGAGTTGGGGAGAGGGCGGTGCT
CACGAGTGTATAAGACCCACAAGACCCTTAGAACCGAAAGACCTTGAGTTCATGATAACCGCGGGAATAGCGGAATTCGA
GGATCCGGAAAATGCTCTGAAGGTTTATGAACTAATATTCAAGAGGTTTATGGCATCCCAGATGAGACCTGCAAAAGTAA
TAACGGAAGAAATCATTTTAAAACTCCCCTACTTTGAGTGGAAGGAAAGGGTTGTAACTGAGGTAAAGGAACACGGTTTT
GACCTCATGTATCCGACCTTCAAAGTCTTTCCCAAAAAAGAAAAACTAGAAATTACACATAAAGAGTTCAGGGAAGTTCC
GAAAGTCTACCCCTACACGCAGGGAACGTTAATTCAGGAGATGAAAAGAAGAGGACTCGGAAGACCTTCAACTTACGCCC
AGATAGTCCAGACGCTTCTTGAAAGGCACTACGTTGTGGAAGAAAAGGGATTTTTAATTCCCACGGATCTAGGAAGGGAA
GTTTACGAATACCTGACCAAGCACTTCCCCGAGTGGACAAGTGAAGAACTCACGAGAAAACTTGAAGAGGCGATGGACAA
AATAGAGAGAGGAGAACTCGATTACATGGAAGTTCTAAAGGAGGTTCACAGGATAAAGGTACTCCTGAAGGAAGAAAAGG
CTTTTAAAAAATAA

Upstream 100 bases:

>100_bases
GTATCCACAAGGGCTGTTCCGTCCTCGTAAACTTCCACAACTTTAGAAGGTATAGCCAAGCACATGTCTACTTTAATAAT
TATATTCCTTCGGTGAATGG

Downstream 100 bases:

>100_bases
AACAATTTTTTGATTTGAATTTCTATAATATTCATTATGTGGGCCAGAGTACTTAAATTAATCTGCGAAGAGTTAGGAGA
CAGAGAGCTGTTCCTCTTGG

Product: reverse gyrase

Products: NA

Alternate protein names: Helicase; Topoisomerase [H]

Number of amino acids: Translated: 1177; Mature: 1177

Protein sequence:

>1177_residues
MFIKKKSKRFPSKSYPIIMALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPTEEKVCDALEELKTLKYLKPFCDTDKS
LERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTGVGKTTFGLVMSLFLKGRVLAIFPTRLLAQQAGDRLSELAQ
KVGVNKKILIYQSKKNIREQFLNGDWDILLGTNMFLHKNFENLINFKFKLIFIDDIDSFLKRGKNVDYLFKLLGFSGEEI
KLALKENKTQRDYDRLARIRKRKRDTVLIVSSATLKPRGKRAYLFRNLLGFDVQKAITTLRNIVDVAEPVKDLEEALEKS
VELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVSYLDYKPEELYQILEKGEFDVAVGISHITNPLVRGIDLPHI
IRYAVFLDPPKHVFPTELTLSPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYLTLREEQLDNYPRIKERVEEIKNFLE
NYLKDENFLKKIKESEDISLVPKEGKLYIVVGDANSYIQASGRTSRFIAGGMTKGLSVVYYSDPKAFYSLKKRLALYYMT
QEIEFKRLSEVDLNKLIKEIDEDRKRAREILQGKGVAQIKDLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVP
LGDRLLVITASLGHVLDLVTDKGFFGVLDDTYPYLPVYDTIKICRETHEQHTEYEYLKKRCKGKIEDKLEIIKGVREVSY
EVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDLNLVKAQLVRRILDRWVGFTLSH
ILWDAFGKKWLSAGRVQTPVLGWVIKRYEESKEKKGEILLHVNDFPLKIEIEDLMFAKEIFKDLELADISLSNPQEEEKR
PLPPYTTDTVLEDANEKLHLSAHKTMKILQELFEAGYITYHRTDSTRVSDAGKYLVAKPYITKMFGEEYFYPRSWGEGGA
HECIRPTRPLEPKDLEFMITAGIAEFEDPENALKVYELIFKRFMASQMRPAKVITEEIILKLPYFEWKERVVTEVKEHGF
DLMYPTFKVFPKKEKLEITHKEFREVPKVYPYTQGTLIQEMKRRGLGRPSTYAQIVQTLLERHYVVEEKGFLIPTDLGRE
VYEYLTKHFPEWTSEELTRKLEEAMDKIERGELDYMEVLKEVHRIKVLLKEEKAFKK

Sequences:

>Translated_1177_residues
MFIKKKSKRFPSKSYPIIMALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPTEEKVCDALEELKTLKYLKPFCDTDKS
LERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTGVGKTTFGLVMSLFLKGRVLAIFPTRLLAQQAGDRLSELAQ
KVGVNKKILIYQSKKNIREQFLNGDWDILLGTNMFLHKNFENLINFKFKLIFIDDIDSFLKRGKNVDYLFKLLGFSGEEI
KLALKENKTQRDYDRLARIRKRKRDTVLIVSSATLKPRGKRAYLFRNLLGFDVQKAITTLRNIVDVAEPVKDLEEALEKS
VELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVSYLDYKPEELYQILEKGEFDVAVGISHITNPLVRGIDLPHI
IRYAVFLDPPKHVFPTELTLSPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYLTLREEQLDNYPRIKERVEEIKNFLE
NYLKDENFLKKIKESEDISLVPKEGKLYIVVGDANSYIQASGRTSRFIAGGMTKGLSVVYYSDPKAFYSLKKRLALYYMT
QEIEFKRLSEVDLNKLIKEIDEDRKRAREILQGKGVAQIKDLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVP
LGDRLLVITASLGHVLDLVTDKGFFGVLDDTYPYLPVYDTIKICRETHEQHTEYEYLKKRCKGKIEDKLEIIKGVREVSY
EVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDLNLVKAQLVRRILDRWVGFTLSH
ILWDAFGKKWLSAGRVQTPVLGWVIKRYEESKEKKGEILLHVNDFPLKIEIEDLMFAKEIFKDLELADISLSNPQEEEKR
PLPPYTTDTVLEDANEKLHLSAHKTMKILQELFEAGYITYHRTDSTRVSDAGKYLVAKPYITKMFGEEYFYPRSWGEGGA
HECIRPTRPLEPKDLEFMITAGIAEFEDPENALKVYELIFKRFMASQMRPAKVITEEIILKLPYFEWKERVVTEVKEHGF
DLMYPTFKVFPKKEKLEITHKEFREVPKVYPYTQGTLIQEMKRRGLGRPSTYAQIVQTLLERHYVVEEKGFLIPTDLGRE
VYEYLTKHFPEWTSEELTRKLEEAMDKIERGELDYMEVLKEVHRIKVLLKEEKAFKK
>Mature_1177_residues
MFIKKKSKRFPSKSYPIIMALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPTEEKVCDALEELKTLKYLKPFCDTDKS
LERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTGVGKTTFGLVMSLFLKGRVLAIFPTRLLAQQAGDRLSELAQ
KVGVNKKILIYQSKKNIREQFLNGDWDILLGTNMFLHKNFENLINFKFKLIFIDDIDSFLKRGKNVDYLFKLLGFSGEEI
KLALKENKTQRDYDRLARIRKRKRDTVLIVSSATLKPRGKRAYLFRNLLGFDVQKAITTLRNIVDVAEPVKDLEEALEKS
VELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVSYLDYKPEELYQILEKGEFDVAVGISHITNPLVRGIDLPHI
IRYAVFLDPPKHVFPTELTLSPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYLTLREEQLDNYPRIKERVEEIKNFLE
NYLKDENFLKKIKESEDISLVPKEGKLYIVVGDANSYIQASGRTSRFIAGGMTKGLSVVYYSDPKAFYSLKKRLALYYMT
QEIEFKRLSEVDLNKLIKEIDEDRKRAREILQGKGVAQIKDLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVP
LGDRLLVITASLGHVLDLVTDKGFFGVLDDTYPYLPVYDTIKICRETHEQHTEYEYLKKRCKGKIEDKLEIIKGVREVSY
EVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDLNLVKAQLVRRILDRWVGFTLSH
ILWDAFGKKWLSAGRVQTPVLGWVIKRYEESKEKKGEILLHVNDFPLKIEIEDLMFAKEIFKDLELADISLSNPQEEEKR
PLPPYTTDTVLEDANEKLHLSAHKTMKILQELFEAGYITYHRTDSTRVSDAGKYLVAKPYITKMFGEEYFYPRSWGEGGA
HECIRPTRPLEPKDLEFMITAGIAEFEDPENALKVYELIFKRFMASQMRPAKVITEEIILKLPYFEWKERVVTEVKEHGF
DLMYPTFKVFPKKEKLEITHKEFREVPKVYPYTQGTLIQEMKRRGLGRPSTYAQIVQTLLERHYVVEEKGFLIPTDLGRE
VYEYLTKHFPEWTSEELTRKLEEAMDKIERGELDYMEVLKEVHRIKVLLKEEKAFKK

Specific function: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DN

COG id: COG1110

COG function: function code L; Reverse gyrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Homo sapiens, GI10835218, Length=511, Percent_Identity=26.2230919765166, Blast_Score=94, Evalue=9e-19,
Organism=Escherichia coli, GI1787529, Length=604, Percent_Identity=28.476821192053, Blast_Score=206, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI32563869, Length=495, Percent_Identity=23.6363636363636, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24585251, Length=575, Percent_Identity=25.2173913043478, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24640096, Length=627, Percent_Identity=22.0095693779904, Blast_Score=92, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR005736
- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013826
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR006171 [H]

Pfam domain/function: PF00270 DEAD; PF01131 Topoisom_bac; PF01751 Toprim [H]

EC number: =3.6.4.12; =5.99.1.3 [H]

Molecular weight: Translated: 136740; Mature: 136740

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIKKKSKRFPSKSYPIIMALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPTEEKVCD
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHCCCCCCHHHHHH
ALEELKTLKYLKPFCDTDKSLERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCC
VGKTTFGLVMSLFLKGRVLAIFPTRLLAQQAGDRLSELAQKVGVNKKILIYQSKKNIREQ
CCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHH
FLNGDWDILLGTNMFLHKNFENLINFKFKLIFIDDIDSFLKRGKNVDYLFKLLGFSGEEI
HCCCCCEEEECCCHHHHCCHHHHHCEEEEEEEEHHHHHHHHCCCCHHHHHHHHCCCCCCE
KLALKENKTQRDYDRLARIRKRKRDTVLIVSSATLKPRGKRAYLFRNLLGFDVQKAITTL
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RNIVDVAEPVKDLEEALEKSVELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEE
YLDYKPEELYQILEKGEFDVAVGISHITNPLVRGIDLPHIIRYAVFLDPPKHVFPTELTL
ECCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCC
SPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYLTLREEQLDNYPRIKERVEEIKNFLE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NYLKDENFLKKIKESEDISLVPKEGKLYIVVGDANSYIQASGRTSRFIAGGMTKGLSVVY
HHHCCHHHHHHHCCCCCCEEECCCCEEEEEEECCCCEEEECCCCCHHHCCCCCCCCEEEE
YSDPKAFYSLKKRLALYYMTQEIEFKRLSEVDLNKLIKEIDEDRKRAREILQGKGVAQIK
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVPLGDRLLVITASLGHVLDLVT
HHHHHHEEEEECCCCCHHHHHHCCCCCHHEECCCCEEECCCCCEEEEEEHHHHHHHHHHH
DKGFFGVLDDTYPYLPVYDTIKICRETHEQHTEYEYLKKRCKGKIEDKLEIIKGVREVSY
CCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
EVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDLNL
HHHEEEEECCCCCCCCCCCEEEEEEECCCCCCEEHHHHHCCCHHHHHHHHCCCHHHHHHH
VKAQLVRRILDRWVGFTLSHILWDAFGKKWLSAGRVQTPVLGWVIKRYEESKEKKGEILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEE
HVNDFPLKIEIEDLMFAKEIFKDLELADISLSNPQEEEKRPLPPYTTDTVLEDANEKLHL
EECCCCEEEEHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCHHHHHHCCCCEEEE
SAHKTMKILQELFEAGYITYHRTDSTRVSDAGKYLVAKPYITKMFGEEYFYPRSWGEGGA
HHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCEEEECHHHHHHHCCCCCCCCCCCCCCC
HECIRPTRPLEPKDLEFMITAGIAEFEDPENALKVYELIFKRFMASQMRPAKVITEEIIL
HHCCCCCCCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KLPYFEWKERVVTEVKEHGFDLMYPTFKVFPKKEKLEITHKEFREVPKVYPYTQGTLIQE
HCCCHHHHHHHHHHHHHCCCCEECCHHHHCCCHHHHHCCHHHHHCCCCCCCCCCCHHHHH
MKRRGLGRPSTYAQIVQTLLERHYVVEEKGFLIPTDLGREVYEYLTKHFPEWTSEELTRK
HHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LEEAMDKIERGELDYMEVLKEVHRIKVLLKEEKAFKK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFIKKKSKRFPSKSYPIIMALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPTEEKVCD
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHCCCCCCHHHHHH
ALEELKTLKYLKPFCDTDKSLERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCC
VGKTTFGLVMSLFLKGRVLAIFPTRLLAQQAGDRLSELAQKVGVNKKILIYQSKKNIREQ
CCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHH
FLNGDWDILLGTNMFLHKNFENLINFKFKLIFIDDIDSFLKRGKNVDYLFKLLGFSGEEI
HCCCCCEEEECCCHHHHCCHHHHHCEEEEEEEEHHHHHHHHCCCCHHHHHHHHCCCCCCE
KLALKENKTQRDYDRLARIRKRKRDTVLIVSSATLKPRGKRAYLFRNLLGFDVQKAITTL
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RNIVDVAEPVKDLEEALEKSVELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEE
YLDYKPEELYQILEKGEFDVAVGISHITNPLVRGIDLPHIIRYAVFLDPPKHVFPTELTL
ECCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCC
SPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYLTLREEQLDNYPRIKERVEEIKNFLE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NYLKDENFLKKIKESEDISLVPKEGKLYIVVGDANSYIQASGRTSRFIAGGMTKGLSVVY
HHHCCHHHHHHHCCCCCCEEECCCCEEEEEEECCCCEEEECCCCCHHHCCCCCCCCEEEE
YSDPKAFYSLKKRLALYYMTQEIEFKRLSEVDLNKLIKEIDEDRKRAREILQGKGVAQIK
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVPLGDRLLVITASLGHVLDLVT
HHHHHHEEEEECCCCCHHHHHHCCCCCHHEECCCCEEECCCCCEEEEEEHHHHHHHHHHH
DKGFFGVLDDTYPYLPVYDTIKICRETHEQHTEYEYLKKRCKGKIEDKLEIIKGVREVSY
CCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
EVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDLNL
HHHEEEEECCCCCCCCCCCEEEEEEECCCCCCEEHHHHHCCCHHHHHHHHCCCHHHHHHH
VKAQLVRRILDRWVGFTLSHILWDAFGKKWLSAGRVQTPVLGWVIKRYEESKEKKGEILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEE
HVNDFPLKIEIEDLMFAKEIFKDLELADISLSNPQEEEKRPLPPYTTDTVLEDANEKLHL
EECCCCEEEEHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCHHHHHHCCCCEEEE
SAHKTMKILQELFEAGYITYHRTDSTRVSDAGKYLVAKPYITKMFGEEYFYPRSWGEGGA
HHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCEEEECHHHHHHHCCCCCCCCCCCCCCC
HECIRPTRPLEPKDLEFMITAGIAEFEDPENALKVYELIFKRFMASQMRPAKVITEEIIL
HHCCCCCCCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KLPYFEWKERVVTEVKEHGFDLMYPTFKVFPKKEKLEITHKEFREVPKVYPYTQGTLIQE
HCCCHHHHHHHHHHHHHCCCCEECCHHHHCCCHHHHHCCHHHHHCCCCCCCCCCCHHHHH
MKRRGLGRPSTYAQIVQTLLERHYVVEEKGFLIPTDLGREVYEYLTKHFPEWTSEELTRK
HHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LEEAMDKIERGELDYMEVLKEVHRIKVLLKEEKAFKK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]