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The map label for this gene is glyQ

Identifier: 15606265

GI number: 15606265

Start: 651393

End: 652250

Strand: Direct

Name: glyQ

Synonym: aq_945

Alternate gene names: 15606265

Gene position: 651393-652250 (Clockwise)

Preceding gene: 15606264

Following gene: 15606266

Centisome position: 41.99

GC content: 46.97

Gene sequence:

>858_bases
ATGTACTTTCAAGACATCATAATGACCCTTCACAAGTTCTGGGCTGAAAAGGGATGTTTAATCTGGCAACCCTACGACGT
TGAAGTCGGTGCAGGGACAATGAACCCTGCCACTTTCCTGAAAGTTCTTGGTAAAAAGCCGTGGAACGTCGCATACGTTG
AACCCTCAAGAAGGCCTCAGGACGGAAGGTACGGAGAAAACCCCAACAGACTCCAGCACTACTACCAGTTTCAGGTAATT
TTAAAGCCCGCACCCCGAAATCCTCAGGAGATTTACCTTGAAAGCCTTGAAAGACTAGGCATAAATCCCCTGGAACACGA
CATAAGGTTCGTGGAAGACGACTGGGAATCTCCTACCTTGGGAGCATGGGGACTCGGCTGGGAGGTCTGGCTTGACGGAA
TGGAAATAACCCAGTTCACCTACTTCCAGCAGGCGGGAGGACTTGACCTTGACGAGATATCCGTTGAGATCACTTACGGA
CTGGAAAGGATAGCGATGTACATACAGGATAAAGACAGCGTTTTTGACATAGAGTGGAAAGAGGGAATAACCTACGGCGA
GATATTCAAGCGTTCGGAGTGGGAGTGGAGCAAGTACAACTTTGAACTTGCAGACACGGATATGCTCTTTCAGGTTTACG
AAATGTTTGAAAAGGAATCAAAAAGGATGGTTGAAGAAGGGCTTATATTCCCCGCTTATGACTACCTCCTGAAGTGTTCC
CACGTGTTTAACATACTGGACGCAAGAGGAGCTATTTCCGTTCAGGAGAGGGCGAGGTACATAAGGAGGATGAACAACCT
TGCAAGGGAAATAGCAAAGCTCTATCTTCAAGTCTTTGAAAATGTTGGAGCAACTTGA

Upstream 100 bases:

>100_bases
AGACGGTAAGCTTGCATTCGTGGGGGTGCCAAACGAAGCGGAAGCACGCAAAGCAATAGAGGAGGGGGTTTAACTTTATA
CCTTTTTATAATCTTTAAGT

Downstream 100 bases:

>100_bases
AAAAAAACTCGGCTACACCTTTAAGGATAAATCTCTACTCGAAAAAGCCTTAACCCACGTATCTTACTCAAAAAAAGAAC
ACTACGAAACTCTTGAGTTC

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVI
LKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYG
LERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS
HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFENVGAT

Sequences:

>Translated_285_residues
MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVI
LKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYG
LERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS
HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFENVGAT
>Mature_285_residues
MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVI
LKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYG
LERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS
HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFENVGAT

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=287, Percent_Identity=59.581881533101, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_AQUAE (O67081)

Other databases:

- EMBL:   AE000657
- PIR:   F70381
- RefSeq:   NP_213644.1
- ProteinModelPortal:   O67081
- SMR:   O67081
- GeneID:   1193623
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_945
- NMPDR:   fig|224324.1.peg.659
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- PhylomeDB:   O67081
- ProtClustDB:   PRK09348
- BioCyc:   AAEO224324:AQ_945-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33673; Mature: 33673

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQ
CCHHHHHHHHHHHHHHCCEEEECCCEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCC
DGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTL
CCCCCCCHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCCC
GAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWK
CCCCCCHHHHCCCCHHHHHHHHHHCCCCCHHHEEEEEEECHHHHHHHHCCCCCEEEEEHH
EGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS
HCCCHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFENVGAT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQ
CCHHHHHHHHHHHHHHCCEEEECCCEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCC
DGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTL
CCCCCCCHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCCC
GAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWK
CCCCCCHHHHCCCCHHHHHHHHHHCCCCCHHHEEEEEEECHHHHHHHHCCCCCEEEEEHH
EGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS
HCCCHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFENVGAT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320