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The map label for this gene is nifU

Identifier: 15606229

GI number: 15606229

Start: 620083

End: 620556

Strand: Direct

Name: nifU

Synonym: aq_896

Alternate gene names: 15606229

Gene position: 620083-620556 (Clockwise)

Preceding gene: 15606226

Following gene: 15606230

Centisome position: 39.97

GC content: 45.99

Gene sequence:

>474_bases
ATGAGCTTCGAATACAATGAGAAGGTTCTTGATCACTTCTTGAACCCGAGGAACGTTGGTGTTCTTGAAGATGCAAACGG
TGTAGGACAGTGTGGTAACCCCGCTTGCGGAGACGCAATGCTCTTTACTATAAAAGTTAATCCTGAAAACGACGTTATAG
AAGACGTAAGGTTTAAGACCTTCGGTTGCGGTTCTGCGATAGCGGTAAGCTCTATGCTCACAGAAATGGTAAAGGGGAAA
CCCATACAGTACGCCCTAAACCTCACCTATAAAGACATATTCGAAGAACTCGGAGGACTGCCACCCCAAAAGATACACTG
CACTAACCTTGGACTCGAAACGCTCCACGTTGCTATAAAGGACTACCTCATGAAGCAGGGTAGAGTAGAGGAAGCTTCCA
AGATACCCGACTGCTACGAAGAAGAGGAAGAACAAGAAGAAAGCAAGGAGTTCGAATTCCTGTCCGGAACGTAA

Upstream 100 bases:

>100_bases
GGCACTATTATAAATAAATTACTTTGATTTCAGTCATAACGTAAACCTTGCAAATGAATGAATTTATAATTCAGTAATAA
ACTATCAAGGAGGTGCTAAA

Downstream 100 bases:

>100_bases
GATGGGAAAAAGAAAAGCTCTGGCCCTCCTTTCCGGGGGGCTTGATAGTTCTCTTGCTGTAAAGCTCGTTCAGGAACAGG
GAATAGAAGTAAAGGCTTTT

Product: NifU protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSFEYNEKVLDHFLNPRNVGVLEDANGVGQCGNPACGDAMLFTIKVNPENDVIEDVRFKTFGCGSAIAVSSMLTEMVKGK
PIQYALNLTYKDIFEELGGLPPQKIHCTNLGLETLHVAIKDYLMKQGRVEEASKIPDCYEEEEEQEESKEFEFLSGT

Sequences:

>Translated_157_residues
MSFEYNEKVLDHFLNPRNVGVLEDANGVGQCGNPACGDAMLFTIKVNPENDVIEDVRFKTFGCGSAIAVSSMLTEMVKGK
PIQYALNLTYKDIFEELGGLPPQKIHCTNLGLETLHVAIKDYLMKQGRVEEASKIPDCYEEEEEQEESKEFEFLSGT
>Mature_156_residues
SFEYNEKVLDHFLNPRNVGVLEDANGVGQCGNPACGDAMLFTIKVNPENDVIEDVRFKTFGCGSAIAVSSMLTEMVKGKP
IQYALNLTYKDIFEELGGLPPQKIHCTNLGLETLHVAIKDYLMKQGRVEEASKIPDCYEEEEEQEESKEFEFLSGT

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential)

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family

Homologues:

Organism=Homo sapiens, GI56699456, Length=125, Percent_Identity=49.6, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI24307953, Length=129, Percent_Identity=48.062015503876, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1788878, Length=125, Percent_Identity=53.6, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17543474, Length=128, Percent_Identity=48.4375, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324800, Length=125, Percent_Identity=48.8, Blast_Score=120, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6325122, Length=125, Percent_Identity=49.6, Blast_Score=119, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21355597, Length=127, Percent_Identity=51.1811023622047, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NIFU_AQUAE (O67045)

Other databases:

- EMBL:   AE000657
- PIR:   B70377
- RefSeq:   NP_213607.1
- PDB:   2Z7E
- PDBsum:   2Z7E
- ProteinModelPortal:   O67045
- SMR:   O67045
- GeneID:   1193587
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_896
- NMPDR:   fig|224324.1.peg.622
- HOGENOM:   HBG584215
- OMA:   DAMLFTI
- PhylomeDB:   O67045
- ProtClustDB:   CLSK2299538
- BioCyc:   AAEO224324:AQ_896-MONOMER
- InterPro:   IPR002871
- PANTHER:   PTHR10093

Pfam domain/function: PF01592 NifU_N

EC number: NA

Molecular weight: Translated: 17531; Mature: 17400

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEYNEKVLDHFLNPRNVGVLEDANGVGQCGNPACGDAMLFTIKVNPENDVIEDVRFKT
CCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHH
FGCGSAIAVSSMLTEMVKGKPIQYALNLTYKDIFEELGGLPPQKIHCTNLGLETLHVAIK
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
DYLMKQGRVEEASKIPDCYEEEEEQEESKEFEFLSGT
HHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFEYNEKVLDHFLNPRNVGVLEDANGVGQCGNPACGDAMLFTIKVNPENDVIEDVRFKT
CCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHH
FGCGSAIAVSSMLTEMVKGKPIQYALNLTYKDIFEELGGLPPQKIHCTNLGLETLHVAIK
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
DYLMKQGRVEEASKIPDCYEEEEEQEESKEFEFLSGT
HHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320