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The map label for this gene is pilQ [H]

Identifier: 15606033

GI number: 15606033

Start: 397306

End: 399423

Strand: Direct

Name: pilQ [H]

Synonym: aq_585

Alternate gene names: 15606033

Gene position: 397306-399423 (Clockwise)

Preceding gene: 15606031

Following gene: 15606035

Centisome position: 25.61

GC content: 35.36

Gene sequence:

>2118_bases
ATGAAGGTTATGCACATATTATTCTTGATTATATTGGCTTTTGCCTTTGCTGAAGATACAATACCCATAAAAAATATCAC
GGGAAGTGGAAGTATAAGTGTTTATAAAGATGGAAAAGTTTTTCACTATAAAATACTTGAGTATTTTGATGAAAGAAAGA
AAACTCTTAAAGCATACGTTGTACGTGAGAGTATTGAAGAAAAAAAATTACACTATGGTAATTTTACTATTATCAATGCC
GATTTTCAAAACTTAAAGTTAGCAACTATTTTAATTTCTCTGTCAAAAATAGCTAATTTAAACATAGTATTCAGTAAAGA
GCTTTGGAAAAGTAGACAAGAAAAGTTCGAACCATCGAAAGAATATAGGGAAGAAGAAGGTTCTTTACTACGGAAAGAAA
AAGGTTTTTTACTCCAATTTTCTACACTTCCAAGAAAAGTAAAAGTAACAAGAAAAGAACCTGTACAGGAAAAGGAAGAA
TACAGAATCCCTTCTTATCTTCTACATAATGTCTCGCTAATTATTAACTCCCCTACGCCGGGTTATACACTTTTTACTCT
TTTTGATACTTTATTACGGGAATACGATCTTATCGCTGTAAAGCTTTCAAATAATCTAATAAAAATATCAAAAAAGGAAA
CATTAGCATTTGATGTAGAAGGTGTTGACCAATCTTCTATTAATAAACTGATTTCGAAGATAAAGCAATATACTTCTCCT
TCGGCGAAAGTCTTATACGACAAGGATTTGGGAAAAATCATGGTCATTGATATGGCAGAAAACATAGAAAAGCTAAGAGA
TTTGAGAGTAGATTTAATAGAACTTTTAATGTCTAGGGAAACTACCCCAGGTGAAAAGGAAAAGTCCAAGGAAACTACCC
CACGTGAAATTGAAACTAAGGTTTTTTACTTCAAGAATAAAAGAGATTTAGAAATAGCCTTAAGTAGATTGAAGGAAAAT
TTTTCGGGAGAAGTAATCCTAAATATAGACAAAGACTTTAATGCCATTATAGTAACAAGTAATAGATCGGTAATAAAATC
TGTCGGCACTCTGCTTAAAGATTTGACGGAAAGTATCGATAAAGCTTATTTGATTACCAAGATTTTCTATGTTAGATATA
TTTCCCCTTACGAACTTAAAAAGAAAATAGAACCTATGCTTTCCGAGGTTGGAGAAGTATACACGTTGAGCGTTTCGAAC
ACAGATGAAAAGAAAGAATTAATAAGCTATAAAAATACTCCTCCAGCTACCGCTTTTAACGAAGGAACTTTGGAGAAAGA
AAAAGCATTTTTTGTTCCGTTTAACAACGCAATTCTCATAAAGGATTACCCTGAAAGGATAGAAAAAATCAGAGAAAAAT
TTAAAAAGTTTCTATCGGAAAAGCCTATAAAGATAAAGATAAGGGCAAAGCTCGTGGAAGTAGAAAAGAGCTTACTGAGG
GAGCTTGGAATTTCATGGAGAACGGTATTTTCAAAAGCTTACATTCCAGAATTCTGGCAGGGAGAAACCGCATTCAGAAC
TGTTACTCCCGGACAACCACAAAGCGGTCTGCTAACATTTACCTTTCAGAGAAACAGATTGAACTTACTTGAATTTAAAC
TTCTCGCTTACGAACAAGAAGGAAGGGCAAAGAATGTTGCAGAGTCTTACGTAATTACGGTTAACGGAGAACCTGCTGTA
ATATCAAGCGGTTTGGAATTCCCGGTAACGGAGGTTTCACTTTCAGGAGGGATAGCAAATGTGGAGCCTAAGTACGAGAG
CATCCCTATAGTACTTATAACCACTCCCGTAGTGCTTCCCGATGGAAACATACTTCTGAGTGTTTACTTGGCGAGAAGGC
AGATAAATTCCGTTCAGGAGTTTCCGGTGACTCAGACTTTAACCCAAAAAATTCCTGTCTTTTCTACTTCACGGATAGAC
GTAAAGATACCTATTAAAAACGGTGAAACTGTAGTAATAGGTGGGGCTGTCGAAAAGTCAGATTCAATAACGGAAAGCGG
AGTACCAAAACTCAGAGAGGTTCCGCTACTTGGCTGGCTCTTCAAAACGCAGACTAAACAACTCAGGGACAGGGAACTGT
TAATCTTCATAACGCCGGAAATAATAGAGGAAGATTAA

Upstream 100 bases:

>100_bases
ATACTGGAAGAGATTACGAAAATATAATCTGTAAAGATGCTGATTTAAGTGGCTACGTTTATTTACTGAACCTTGTAACT
ATAAATGTGGAGGGGAAGAA

Downstream 100 bases:

>100_bases
AGGGAGGAAAGTTTTGAAAGTATCTTTTCCCTCCACTTTCTCGCCTTTGCGAAAATTTCTTCCTGATCCACTGTTTTAAG
TTCCCTCTTTTCCATTAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Outer membrane protein omc [H]

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MKVMHILFLIILAFAFAEDTIPIKNITGSGSISVYKDGKVFHYKILEYFDERKKTLKAYVVRESIEEKKLHYGNFTIINA
DFQNLKLATILISLSKIANLNIVFSKELWKSRQEKFEPSKEYREEEGSLLRKEKGFLLQFSTLPRKVKVTRKEPVQEKEE
YRIPSYLLHNVSLIINSPTPGYTLFTLFDTLLREYDLIAVKLSNNLIKISKKETLAFDVEGVDQSSINKLISKIKQYTSP
SAKVLYDKDLGKIMVIDMAENIEKLRDLRVDLIELLMSRETTPGEKEKSKETTPREIETKVFYFKNKRDLEIALSRLKEN
FSGEVILNIDKDFNAIIVTSNRSVIKSVGTLLKDLTESIDKAYLITKIFYVRYISPYELKKKIEPMLSEVGEVYTLSVSN
TDEKKELISYKNTPPATAFNEGTLEKEKAFFVPFNNAILIKDYPERIEKIREKFKKFLSEKPIKIKIRAKLVEVEKSLLR
ELGISWRTVFSKAYIPEFWQGETAFRTVTPGQPQSGLLTFTFQRNRLNLLEFKLLAYEQEGRAKNVAESYVITVNGEPAV
ISSGLEFPVTEVSLSGGIANVEPKYESIPIVLITTPVVLPDGNILLSVYLARRQINSVQEFPVTQTLTQKIPVFSTSRID
VKIPIKNGETVVIGGAVEKSDSITESGVPKLREVPLLGWLFKTQTKQLRDRELLIFITPEIIEED

Sequences:

>Translated_705_residues
MKVMHILFLIILAFAFAEDTIPIKNITGSGSISVYKDGKVFHYKILEYFDERKKTLKAYVVRESIEEKKLHYGNFTIINA
DFQNLKLATILISLSKIANLNIVFSKELWKSRQEKFEPSKEYREEEGSLLRKEKGFLLQFSTLPRKVKVTRKEPVQEKEE
YRIPSYLLHNVSLIINSPTPGYTLFTLFDTLLREYDLIAVKLSNNLIKISKKETLAFDVEGVDQSSINKLISKIKQYTSP
SAKVLYDKDLGKIMVIDMAENIEKLRDLRVDLIELLMSRETTPGEKEKSKETTPREIETKVFYFKNKRDLEIALSRLKEN
FSGEVILNIDKDFNAIIVTSNRSVIKSVGTLLKDLTESIDKAYLITKIFYVRYISPYELKKKIEPMLSEVGEVYTLSVSN
TDEKKELISYKNTPPATAFNEGTLEKEKAFFVPFNNAILIKDYPERIEKIREKFKKFLSEKPIKIKIRAKLVEVEKSLLR
ELGISWRTVFSKAYIPEFWQGETAFRTVTPGQPQSGLLTFTFQRNRLNLLEFKLLAYEQEGRAKNVAESYVITVNGEPAV
ISSGLEFPVTEVSLSGGIANVEPKYESIPIVLITTPVVLPDGNILLSVYLARRQINSVQEFPVTQTLTQKIPVFSTSRID
VKIPIKNGETVVIGGAVEKSDSITESGVPKLREVPLLGWLFKTQTKQLRDRELLIFITPEIIEED
>Mature_705_residues
MKVMHILFLIILAFAFAEDTIPIKNITGSGSISVYKDGKVFHYKILEYFDERKKTLKAYVVRESIEEKKLHYGNFTIINA
DFQNLKLATILISLSKIANLNIVFSKELWKSRQEKFEPSKEYREEEGSLLRKEKGFLLQFSTLPRKVKVTRKEPVQEKEE
YRIPSYLLHNVSLIINSPTPGYTLFTLFDTLLREYDLIAVKLSNNLIKISKKETLAFDVEGVDQSSINKLISKIKQYTSP
SAKVLYDKDLGKIMVIDMAENIEKLRDLRVDLIELLMSRETTPGEKEKSKETTPREIETKVFYFKNKRDLEIALSRLKEN
FSGEVILNIDKDFNAIIVTSNRSVIKSVGTLLKDLTESIDKAYLITKIFYVRYISPYELKKKIEPMLSEVGEVYTLSVSN
TDEKKELISYKNTPPATAFNEGTLEKEKAFFVPFNNAILIKDYPERIEKIREKFKKFLSEKPIKIKIRAKLVEVEKSLLR
ELGISWRTVFSKAYIPEFWQGETAFRTVTPGQPQSGLLTFTFQRNRLNLLEFKLLAYEQEGRAKNVAESYVITVNGEPAV
ISSGLEFPVTEVSLSGGIANVEPKYESIPIVLITTPVVLPDGNILLSVYLARRQINSVQEFPVTQTLTQKIPVFSTSRID
VKIPIKNGETVVIGGAVEKSDSITESGVPKLREVPLLGWLFKTQTKQLRDRELLIFITPEIIEED

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane. Note=Associated to the membrane through its C-terminus [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=273, Percent_Identity=24.5421245421245, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 80773; Mature: 80773

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVMHILFLIILAFAFAEDTIPIKNITGSGSISVYKDGKVFHYKILEYFDERKKTLKAYV
CHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHH
VRESIEEKKLHYGNFTIINADFQNLKLATILISLSKIANLNIVFSKELWKSRQEKFEPSK
HHHHHHHHHEECCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCH
EYREEEGSLLRKEKGFLLQFSTLPRKVKVTRKEPVQEKEEYRIPSYLLHNVSLIINSPTP
HHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHCCCHHHHHCCEEEEEECCCC
GYTLFTLFDTLLREYDLIAVKLSNNLIKISKKETLAFDVEGVDQSSINKLISKIKQYTSP
CEEHHHHHHHHHHCCCEEEEEECCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCC
SAKVLYDKDLGKIMVIDMAENIEKLRDLRVDLIELLMSRETTPGEKEKSKETTPREIETK
CCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHEEE
VFYFKNKRDLEIALSRLKENFSGEVILNIDKDFNAIIVTSNRSVIKSVGTLLKDLTESID
EEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
KAYLITKIFYVRYISPYELKKKIEPMLSEVGEVYTLSVSNTDEKKELISYKNTPPATAFN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCC
EGTLEKEKAFFVPFNNAILIKDYPERIEKIREKFKKFLSEKPIKIKIRAKLVEVEKSLLR
CCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHH
ELGISWRTVFSKAYIPEFWQGETAFRTVTPGQPQSGLLTFTFQRNRLNLLEFKLLAYEQE
HHCCHHHHHHHHHCCCHHHCCCCEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEEECC
GRAKNVAESYVITVNGEPAVISSGLEFPVTEVSLSGGIANVEPKYESIPIVLITTPVVLP
CCCCCCCCEEEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCEEEC
DGNILLSVYLARRQINSVQEFPVTQTLTQKIPVFSTSRIDVKIPIKNGETVVIGGAVEKS
CCCEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCEEEEEEEECCCCEEEEECCCCCC
DSITESGVPKLREVPLLGWLFKTQTKQLRDRELLIFITPEIIEED
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEEECHHHHCCC
>Mature Secondary Structure
MKVMHILFLIILAFAFAEDTIPIKNITGSGSISVYKDGKVFHYKILEYFDERKKTLKAYV
CHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHH
VRESIEEKKLHYGNFTIINADFQNLKLATILISLSKIANLNIVFSKELWKSRQEKFEPSK
HHHHHHHHHEECCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCH
EYREEEGSLLRKEKGFLLQFSTLPRKVKVTRKEPVQEKEEYRIPSYLLHNVSLIINSPTP
HHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHCCCHHHHHCCEEEEEECCCC
GYTLFTLFDTLLREYDLIAVKLSNNLIKISKKETLAFDVEGVDQSSINKLISKIKQYTSP
CEEHHHHHHHHHHCCCEEEEEECCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCC
SAKVLYDKDLGKIMVIDMAENIEKLRDLRVDLIELLMSRETTPGEKEKSKETTPREIETK
CCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHEEE
VFYFKNKRDLEIALSRLKENFSGEVILNIDKDFNAIIVTSNRSVIKSVGTLLKDLTESID
EEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
KAYLITKIFYVRYISPYELKKKIEPMLSEVGEVYTLSVSNTDEKKELISYKNTPPATAFN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCC
EGTLEKEKAFFVPFNNAILIKDYPERIEKIREKFKKFLSEKPIKIKIRAKLVEVEKSLLR
CCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHH
ELGISWRTVFSKAYIPEFWQGETAFRTVTPGQPQSGLLTFTFQRNRLNLLEFKLLAYEQE
HHCCHHHHHHHHHCCCHHHCCCCEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEEECC
GRAKNVAESYVITVNGEPAVISSGLEFPVTEVSLSGGIANVEPKYESIPIVLITTPVVLP
CCCCCCCCEEEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCEEEC
DGNILLSVYLARRQINSVQEFPVTQTLTQKIPVFSTSRIDVKIPIKNGETVVIGGAVEKS
CCCEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCEEEEEEEECCCCEEEEECCCCCC
DSITESGVPKLREVPLLGWLFKTQTKQLRDRELLIFITPEIIEED
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA