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The map label for this gene is dapE [H]

Identifier: 15606006

GI number: 15606006

Start: 371023

End: 371922

Strand: Direct

Name: dapE [H]

Synonym: aq_547

Alternate gene names: 15606006

Gene position: 371023-371922 (Clockwise)

Preceding gene: 15606004

Following gene: 15606013

Centisome position: 23.92

GC content: 45.11

Gene sequence:

>900_bases
ATGGTTATCAGGGAAGCGGTGAAGGAGACTCTCAAAGAACTCATAAGGATTCCGAGCGTATCTGGAAAGGAAAAGGGAGT
GCTGGAGTACGTAGAAAACAGACTCAAAAGCCTTGGTATTCCTCTAAAGAGACAGGAAATAGAAAAGGACAGGTATAACC
TCGTTTACGACAACGGTTCGGAGTACCTGATTTCAGTTCACGTAGACACTGTACCGCCTGCAGGTTTCAGGGACGCTTAC
AGGCCGAAGGAGGTAAACGGAAGGATTTACGGGAGGGGAGCGAGCGACGTTAAAGGCGCAATAGCGAGCTTAATTACCGC
GGTTGAGTGGTTCAAAAAGGATTTTCCCGAAAAGGAACTGCCCGTTTCCCTTGCTTTTGTCGTTGACGAGGAACAAAACA
CGGCCCTTGGTTCTGAAAACTTGCCAAAGTGTCTAAACGGAAAGAGGAAGTGTATAGTCCTTGAACCCACTTATGGGCTC
GTTTGCACGAAGCAGTATGGAGCTTACGAGTTTTCGGTAAAGATAAAGTGCAAATCCGCCCACGGTTCTGAGTTCGAAAA
GGTTGAAAATCCCGTAAAGGTATTTATAAAACTCCTAAACAAACTCGAAGAAGTCCTGAAAAGGGAAGTAAACGTAATAA
TGGTAAGGAGCGGCACGAAAGTCTACACCGTTCCCAAAACCTGTGAAGCTCTCCTAGAGTTTAAGGTTTTTGAAGGGGAA
AGGAAGGAAGAGCTTGAGAAGAAGGTTCAAGAGGTGGTGAGTGCTTTAAACACAGAGTGTGAAATCACTGTAAAACTGGA
AGGCTTTGAGGAGTTTCAGGAGTTCAACACGGACGGACTATTAGATGTGGTTAAAAAGGCTCTTTTAAAAGGTGGAAGGA
GAAGCAAAAGGAAGGGATAA

Upstream 100 bases:

>100_bases
AGATAAAAACCCTTTCTCCGTCCGTGTACATCTGCATTCTTTTGCCCCTCCTTGTGGAGTTTTAGGACTTCTTTTATTTT
AACGTATATTTTTATTTCTT

Downstream 100 bases:

>100_bases
TGCCTTCCTGGACTCATGCGAGCAATTACCATAAGGCGGGATACACTGCCTGGCTTTTGGTTACCGGAAGCCTTATAGAC
AGTCACACGGACAGGGAGAG

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MVIREAVKETLKELIRIPSVSGKEKGVLEYVENRLKSLGIPLKRQEIEKDRYNLVYDNGSEYLISVHVDTVPPAGFRDAY
RPKEVNGRIYGRGASDVKGAIASLITAVEWFKKDFPEKELPVSLAFVVDEEQNTALGSENLPKCLNGKRKCIVLEPTYGL
VCTKQYGAYEFSVKIKCKSAHGSEFEKVENPVKVFIKLLNKLEEVLKREVNVIMVRSGTKVYTVPKTCEALLEFKVFEGE
RKEELEKKVQEVVSALNTECEITVKLEGFEEFQEFNTDGLLDVVKKALLKGGRRSKRKG

Sequences:

>Translated_299_residues
MVIREAVKETLKELIRIPSVSGKEKGVLEYVENRLKSLGIPLKRQEIEKDRYNLVYDNGSEYLISVHVDTVPPAGFRDAY
RPKEVNGRIYGRGASDVKGAIASLITAVEWFKKDFPEKELPVSLAFVVDEEQNTALGSENLPKCLNGKRKCIVLEPTYGL
VCTKQYGAYEFSVKIKCKSAHGSEFEKVENPVKVFIKLLNKLEEVLKREVNVIMVRSGTKVYTVPKTCEALLEFKVFEGE
RKEELEKKVQEVVSALNTECEITVKLEGFEEFQEFNTDGLLDVVKKALLKGGRRSKRKG
>Mature_299_residues
MVIREAVKETLKELIRIPSVSGKEKGVLEYVENRLKSLGIPLKRQEIEKDRYNLVYDNGSEYLISVHVDTVPPAGFRDAY
RPKEVNGRIYGRGASDVKGAIASLITAVEWFKKDFPEKELPVSLAFVVDEEQNTALGSENLPKCLNGKRKCIVLEPTYGL
VCTKQYGAYEFSVKIKCKSAHGSEFEKVENPVKVFIKLLNKLEEVLKREVNVIMVRSGTKVYTVPKTCEALLEFKVFEGE
RKEELEKKVQEVVSALNTECEITVKLEGFEEFQEFNTDGLLDVVKKALLKGGRRSKRKG

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=210, Percent_Identity=25.2380952380952, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 33841; Mature: 33841

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIREAVKETLKELIRIPSVSGKEKGVLEYVENRLKSLGIPLKRQEIEKDRYNLVYDNGS
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCC
EYLISVHVDTVPPAGFRDAYRPKEVNGRIYGRGASDVKGAIASLITAVEWFKKDFPEKEL
EEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PVSLAFVVDEEQNTALGSENLPKCLNGKRKCIVLEPTYGLVCTKQYGAYEFSVKIKCKSA
CEEEEEEEECCCCCCCCCCCCCHHHCCCCEEEEECCCCCEEEEECCCCEEEEEEEEEECC
HGSEFEKVENPVKVFIKLLNKLEEVLKREVNVIMVRSGTKVYTVPKTCEALLEFKVFEGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECHHHHHHHHHHHHCCCC
RKEELEKKVQEVVSALNTECEITVKLEGFEEFQEFNTDGLLDVVKKALLKGGRRSKRKG
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVIREAVKETLKELIRIPSVSGKEKGVLEYVENRLKSLGIPLKRQEIEKDRYNLVYDNGS
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCC
EYLISVHVDTVPPAGFRDAYRPKEVNGRIYGRGASDVKGAIASLITAVEWFKKDFPEKEL
EEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PVSLAFVVDEEQNTALGSENLPKCLNGKRKCIVLEPTYGLVCTKQYGAYEFSVKIKCKSA
CEEEEEEEECCCCCCCCCCCCCHHHCCCCEEEEECCCCCEEEEECCCCEEEEEEEEEECC
HGSEFEKVENPVKVFIKLLNKLEEVLKREVNVIMVRSGTKVYTVPKTCEALLEFKVFEGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECHHHHHHHHHHHHCCCC
RKEELEKKVQEVVSALNTECEITVKLEGFEEFQEFNTDGLLDVVKKALLKGGRRSKRKG
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA