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The map label for this gene is ftsZ

Identifier: 15605992

GI number: 15605992

Start: 356843

End: 357946

Strand: Direct

Name: ftsZ

Synonym: aq_525

Alternate gene names: 15605992

Gene position: 356843-357946 (Clockwise)

Preceding gene: 15605991

Following gene: 15605993

Centisome position: 23.0

GC content: 46.29

Gene sequence:

>1104_bases
ATGGAGGAGTTCGTGAACCCCTGCAAGATAAAGGTGATAGGCGTAGGCGGAGGGGGAAGTAACGCTGTAAACAGGATGTA
CGAGGACGGTATAGAAGGAGTTGAACTGTATGCGATAAATACGGACGTGCAGCACCTGAGTACTCTTAAGGTTCCAAACA
AGATACAGATAGGGGAAAAGGTAACGAGGGGGCTCGGAGCCGGGGCAAAACCAGAAGTAGGAGAGGAAGCGGCTTTAGAA
GATATAGATAAAATCAAAGAAATTTTGAGAGATACGGACATGGTGTTTATCTCAGCCGGACTCGGTGGAGGTACGGGAAC
GGGAGCAGCTCCCGTAATAGCTAAAACCGCCAAAGAAATGGGAATACTAACCGTTGCGGTAGCAACTCTGCCCTTCAGGT
TTGAAGGTCCAAGGAAGATGGAAAAGGCTCTAAAAGGACTTGAAAAGTTAAAGGAGTCTTCTGACGCTTACATAGTAATA
CACAACGACAAAATAAAGGAACTCTCAAACAGGACACTGACTATAAAAGACGCCTTTAAGGAAGTAGACTCTGTCCTTTC
AAAAGCTGTCAGGGGTATAACGAGTATAGTTGTCACTCCCGCTGTCATAAACGTGGACTTTGCGGATGTGAGAACAACGC
TTGAAGAAGGTGGACTCTCGATAATAGGTATGGGAGAAGGAAGGGGAGACGAAAAGGCGGATATAGCTGTAGAAAAGGCT
GTAACGAGCCCGCTTCTAGAAGGAAATACGATAGAGGGTGCGAGAAGACTTCTCGTTACTATATGGACCTCCGAGGACAT
ACCCTACGACATAGTGGACGAAGTCATGGAAAGGATCCACTCAAAGGTTCACCCGGAAGCAGAAATAATATTCGGTGCTG
TTCTGGAACCCCAGGAGCAGGACTTTATAAGGGTGGCCATTGTAGCCACGGACTTTCCCGAAGAGAAGTTCCAGGTAGGT
GAAAAGGAAGTTAAGTTCAAAGTTATAAAGAAGGAGGAAAAGGAAGAACCGAAGGAAGAACCTAAACCTTTATCCGATAC
GACCTATCTGGAAGAGGAGGAAATACCCGCGGTAATCAGAAGGAAGAATAAGCGGTTGCTATGA

Upstream 100 bases:

>100_bases
TATAACTGAATCTACAAACAGTAATACAGGAAATTTCTTCAAAAATTTATCGGAAAGATTTAAGAAATGGTTTGAGGAAC
TCTTGTGAAGGAGGGCTAAT

Downstream 100 bases:

>100_bases
GAACCGTAGACATAACGACGAAGATAGAGACCTTAAGAGAGGCGAAGGCTTACGGCAGGATAAGGTTAAAGCCCGAAACC
GTAAAACTGATTAAGGAAAA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEKVTRGLGAGAKPEVGEEAALE
DIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEMGILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVI
HNDKIKELSNRTLTIKDAFKEVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKA
VTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQDFIRVAIVATDFPEEKFQVG
EKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIRRKNKRLL

Sequences:

>Translated_367_residues
MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEKVTRGLGAGAKPEVGEEAALE
DIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEMGILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVI
HNDKIKELSNRTLTIKDAFKEVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKA
VTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQDFIRVAIVATDFPEEKFQVG
EKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIRRKNKRLL
>Mature_367_residues
MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEKVTRGLGAGAKPEVGEEAALE
DIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEMGILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVI
HNDKIKELSNRTLTIKDAFKEVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKA
VTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQDFIRVAIVATDFPEEKFQVG
EKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIRRKNKRLL

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family

Homologues:

Organism=Escherichia coli, GI1786284, Length=361, Percent_Identity=41.8282548476454, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FTSZ_AQUAE (O66809)

Other databases:

- EMBL:   AE000657
- PIR:   E70347
- RefSeq:   NP_213369.1
- PDB:   2R6R
- PDB:   2R75
- PDBsum:   2R6R
- PDBsum:   2R75
- ProteinModelPortal:   O66809
- SMR:   O66809
- GeneID:   1193227
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_525
- NMPDR:   fig|224324.1.peg.384
- HOGENOM:   HBG478075
- OMA:   SEMENYN
- ProtClustDB:   PRK09330
- BioCyc:   AAEO224324:AQ_525-MONOMER
- GO:   GO:0005737
- GO:   GO:0005874
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR000217
- InterPro:   IPR018316
- InterPro:   IPR003008
- Gene3D:   G3DSA:3.30.1330.20
- Gene3D:   G3DSA:3.40.50.1440
- PANTHER:   PTHR11588
- PRINTS:   PR00423
- SMART:   SM00864
- SMART:   SM00865
- TIGRFAMs:   TIGR00065

Pfam domain/function: PF00091 Tubulin; SSF55307 Tub_FtsZ_C; SSF52490 Tubulin_FtsZ

EC number: NA

Molecular weight: Translated: 40162; Mature: 40162

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01134 FTSZ_1; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEK
CCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCEEHHHH
VTRGLGAGAKPEVGEEAALEDIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
GILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVIHNDKIKELSNRTLTIKDAFK
HHHEEEEHHCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCEEEHHHHHH
EVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKA
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHH
VTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQ
HHCCCCCCCCHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCC
DFIRVAIVATDFPEEKFQVGEKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIR
CEEEEEEEEECCCHHHHHCCCHHHEEEEECCHHHCCCCCCCCCCCCCCCCCHHCCHHHHH
RKNKRLL
HCCCCCC
>Mature Secondary Structure
MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEK
CCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCEEHHHH
VTRGLGAGAKPEVGEEAALEDIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
GILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVIHNDKIKELSNRTLTIKDAFK
HHHEEEEHHCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCEEEHHHHHH
EVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKA
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHH
VTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQ
HHCCCCCCCCHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCC
DFIRVAIVATDFPEEKFQVGEKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIR
CEEEEEEEEECCCHHHHHCCCHHHEEEEECCHHHCCCCCCCCCCCCCCCCCHHCCHHHHH
RKNKRLL
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320