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The map label for this gene is aspC3 [C]

Identifier: 15605920

GI number: 15605920

Start: 288568

End: 289689

Strand: Direct

Name: aspC3 [C]

Synonym: aq_421

Alternate gene names: 15605920

Gene position: 288568-289689 (Clockwise)

Preceding gene: 15605916

Following gene: 15605921

Centisome position: 18.6

GC content: 45.72

Gene sequence:

>1122_bases
ATGGACAGGCTTGAAAAAGTATCACCCTTCATAGTAATGGATATCCTAGCTCAGGCCCAGAAGTACGAAGACGTAGTACA
CATGGAGATAGGAGAGCCCGATTTAGAACCGTCTCCCAAGGTAATGGAAGCTCTGGAACGTGCGGTGAAGGAAAAGACGT
TCTTCTACACCCCTGCTCTGGGACTCTGGGAACTCAGGGAAAGGATATCGGAGTTTTACAGGAAAAAGTACAGCGTTGAA
GTTTCTCCAGAGAGAGTCATCGTAACTACCGGAACTTCGGGAGCGTTTCTCGTAGCCTACGCCGTAACACTAAATGCGGG
AGAGAAGATAATCCTCCCAGACCCCTCTTACCCCTGTTACAAAAACTTTGCCTACCTCTTAGACGCTCAGCCGGTTTTCG
TAAACGTTGACAAGGAAACGAATTACGAAGTAAGGAAAGAGATGATAGAAGACATTGATGCGAAAGCCCTTCACATTTCC
TCGCCTCAAAACCCTACGGGCACACTCTACTCACCTGAAACCCTGAAGGAACTTGCGGAGTACTGCGAAGAGAAGGGTAT
GTACTTCATATCCGACGAGATTTACCACGGACTCGTTTACGAAGGTAGGGAGCACACAGCACTTGAGTTCTCTGACAGGG
CTATTGTCATAAACGGGTTTTCTAAGTACTTCTGTATGCCAGGTTTCAGGATAGGGTGGATGATAGTTCCGGAAGAACTC
GTGAGAAAGGCGGAAATAGTAATTCAGAACGTATTTATATCTGCCCCGACGCTCAGTCAGTACGCCGCCCTTGAGGCTTT
TGATTACGAGTATTTGGAGAAGGTAAGAAAAACCTTTGAAGAGAGGAGGAACTTCCTTTATGGGGAACTGAAAAAACTCT
TCAAGATAGACGCGAAACCTCAGGGAGCTTTTTACGTATGGGCAAACATAAGTGATTACTCCACAGATAGCTACGAATTT
GCTTTAAAACTTTTAAGGGAGGCGAGGGTGGCGGTAACGCCCGGGGTGGACTTTGGAAAAAACAAAACGAAGGAGTATAT
AAGGTTTGCTTATACGAGAAAGATAGAAGAACTTAAGGAGGGCGTTGAAAGGATAAAGAAGTTCTTAGAGAAGCTTAGCT
GA

Upstream 100 bases:

>100_bases
GTAGAAGTCTATCTCGGAGAGTTCTCTGATAAGTTCTAATTCAAGGTTATTTTTTCTGAATCTTTTCATAAGTAATTATT
CTATATCTAGAATAGTTTTT

Downstream 100 bases:

>100_bases
TCTAAAATACTCTCTATGGAAGAAAAGGCTTTAATAGGGATAGAAGACTTTTTAAAAGTAGATCTCAGAGTAGCAAAGGT
TCTGTCCGCCGAAAGGGTAG

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MDRLEKVSPFIVMDILAQAQKYEDVVHMEIGEPDLEPSPKVMEALERAVKEKTFFYTPALGLWELRERISEFYRKKYSVE
VSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSYPCYKNFAYLLDAQPVFVNVDKETNYEVRKEMIEDIDAKALHIS
SPQNPTGTLYSPETLKELAEYCEEKGMYFISDEIYHGLVYEGREHTALEFSDRAIVINGFSKYFCMPGFRIGWMIVPEEL
VRKAEIVIQNVFISAPTLSQYAALEAFDYEYLEKVRKTFEERRNFLYGELKKLFKIDAKPQGAFYVWANISDYSTDSYEF
ALKLLREARVAVTPGVDFGKNKTKEYIRFAYTRKIEELKEGVERIKKFLEKLS

Sequences:

>Translated_373_residues
MDRLEKVSPFIVMDILAQAQKYEDVVHMEIGEPDLEPSPKVMEALERAVKEKTFFYTPALGLWELRERISEFYRKKYSVE
VSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSYPCYKNFAYLLDAQPVFVNVDKETNYEVRKEMIEDIDAKALHIS
SPQNPTGTLYSPETLKELAEYCEEKGMYFISDEIYHGLVYEGREHTALEFSDRAIVINGFSKYFCMPGFRIGWMIVPEEL
VRKAEIVIQNVFISAPTLSQYAALEAFDYEYLEKVRKTFEERRNFLYGELKKLFKIDAKPQGAFYVWANISDYSTDSYEF
ALKLLREARVAVTPGVDFGKNKTKEYIRFAYTRKIEELKEGVERIKKFLEKLS
>Mature_373_residues
MDRLEKVSPFIVMDILAQAQKYEDVVHMEIGEPDLEPSPKVMEALERAVKEKTFFYTPALGLWELRERISEFYRKKYSVE
VSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSYPCYKNFAYLLDAQPVFVNVDKETNYEVRKEMIEDIDAKALHIS
SPQNPTGTLYSPETLKELAEYCEEKGMYFISDEIYHGLVYEGREHTALEFSDRAIVINGFSKYFCMPGFRIGWMIVPEEL
VRKAEIVIQNVFISAPTLSQYAALEAFDYEYLEKVRKTFEERRNFLYGELKKLFKIDAKPQGAFYVWANISDYSTDSYEF
ALKLLREARVAVTPGVDFGKNKTKEYIRFAYTRKIEELKEGVERIKKFLEKLS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=24.8081841432225, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=24.8081841432225, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI56713256, Length=385, Percent_Identity=25.974025974026, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI56713254, Length=385, Percent_Identity=25.974025974026, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4507369, Length=387, Percent_Identity=22.9974160206718, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881281, Length=301, Percent_Identity=23.2558139534884, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI187936925, Length=350, Percent_Identity=25.1428571428571, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI14211921, Length=350, Percent_Identity=25.1428571428571, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=23.8482384823848, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=23.8482384823848, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI149944424, Length=285, Percent_Identity=27.3684210526316, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=27.319587628866, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788627, Length=397, Percent_Identity=23.1738035264484, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786816, Length=383, Percent_Identity=22.4543080939948, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787909, Length=359, Percent_Identity=20.6128133704735, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787710, Length=327, Percent_Identity=22.6299694189602, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=28.3018867924528, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=394, Percent_Identity=25.8883248730964, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=394, Percent_Identity=26.3959390862944, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=371, Percent_Identity=22.3719676549865, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=351, Percent_Identity=23.9316239316239, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=383, Percent_Identity=24.0208877284595, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=368, Percent_Identity=23.3695652173913, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573069, Length=409, Percent_Identity=23.2273838630807, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24646114, Length=409, Percent_Identity=23.2273838630807, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28573067, Length=409, Percent_Identity=23.2273838630807, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28573065, Length=409, Percent_Identity=23.2273838630807, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=23.3243967828418, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356535, Length=376, Percent_Identity=22.3404255319149, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43221; Mature: 43221

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEKVSPFIVMDILAQAQKYEDVVHMEIGEPDLEPSPKVMEALERAVKEKTFFYTPAL
CCCHHHHCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEECCCC
GLWELRERISEFYRKKYSVEVSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSYPCY
CHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCEEEEEEEEECCCCEEEECCCCCCHH
KNFAYLLDAQPVFVNVDKETNYEVRKEMIEDIDAKALHISSPQNPTGTLYSPETLKELAE
HCCEEEEECCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHH
YCEEKGMYFISDEIYHGLVYEGREHTALEFSDRAIVINGFSKYFCMPGFRIGWMIVPEEL
HHHHCCCEEEEHHHHHHHEECCCCCCEEEECCCEEEEECCHHHHCCCCCEEEEEECCHHH
VRKAEIVIQNVFISAPTLSQYAALEAFDYEYLEKVRKTFEERRNFLYGELKKLFKIDAKP
HHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGAFYVWANISDYSTDSYEFALKLLREARVAVTPGVDFGKNKTKEYIRFAYTRKIEELKE
CCCEEEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVERIKKFLEKLS
HHHHHHHHHHHCC
>Mature Secondary Structure
MDRLEKVSPFIVMDILAQAQKYEDVVHMEIGEPDLEPSPKVMEALERAVKEKTFFYTPAL
CCCHHHHCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEECCCC
GLWELRERISEFYRKKYSVEVSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSYPCY
CHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCEEEEEEEEECCCCEEEECCCCCCHH
KNFAYLLDAQPVFVNVDKETNYEVRKEMIEDIDAKALHISSPQNPTGTLYSPETLKELAE
HCCEEEEECCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHH
YCEEKGMYFISDEIYHGLVYEGREHTALEFSDRAIVINGFSKYFCMPGFRIGWMIVPEEL
HHHHCCCEEEEHHHHHHHEECCCCCCEEEECCCEEEEECCHHHHCCCCCEEEEEECCHHH
VRKAEIVIQNVFISAPTLSQYAALEAFDYEYLEKVRKTFEERRNFLYGELKKLFKIDAKP
HHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGAFYVWANISDYSTDSYEFALKLLREARVAVTPGVDFGKNKTKEYIRFAYTRKIEELKE
CCCEEEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVERIKKFLEKLS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]