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The map label for this gene is lolC [H]

Identifier: 15605828

GI number: 15605828

Start: 191380

End: 192630

Strand: Direct

Name: lolC [H]

Synonym: aq_296

Alternate gene names: 15605828

Gene position: 191380-192630 (Clockwise)

Preceding gene: 15605827

Following gene: 15605829

Centisome position: 12.34

GC content: 42.69

Gene sequence:

>1251_bases
ATGAGGGCTGTTCTCTTTCTGTCCTTTAAGTTCTTCGTGGAGAGGAAAAGACAGAGCTTTATAGCTACTCTGGGGGTGAT
GATAGGAACGACTGCTTACATCGTTATGAGTTCAATGGTAAACGGCTTTCAGAAGTACTTCTTAGAAGAAGCCCTTAACA
TAAACGGACACGTAAAGATATTCGTGGAAGCAAGGGAAAAGGGAGAAAGTTTTTTAAAAAAGTTCTTTCCCGATAAAAAC
TTCAAGATTCTGGGAGAAAAACCGGAAGAGACAAAGGACAAAATAGCGAACTACCGTGAAATCCTGAGGAAATATTCACA
GGATAAAAACGTCATAGGGATAACCGTTCACCTCATCGGAAACGGAGTCCTCACTTACGGGGTAAAGGAAAAACCCGCTA
CCTTTGTGGGCATAATCCCAAAGCTTGAGGACAAAACTTTAAACGTTTCAAAGTATTTACAAGAGGGAAGACTTAACGAA
CTTGAAAGAAACAAGGACTACGTAATTCTCGGTATAAAGCTCGCTCAGGAACTGGGAATAAGGGAAACGGGAAAAAAGGT
TCTCCTTTACGCTCCGAGCGGTGAGGTCTACAGACTCAAAGTAATAGACTTTCTAAACACCGGGATAACCGAGATAGATA
AGTCCAGAATCTACCTTCACATAAAGAAGCTCCAAGACATTCTTGAAAGACAAGGGGAAGTAAATGAAGTAGTTTTAAAG
CTAAAGGATCCAGACCTTGCACCTTTTTACGCGGAAAAGCTCTCAAGAGAAACGGGCTACAAGGCGGAAAGCTGGCAGGA
GTCTTTTAAAAACTTCCTCTCTATATTCAAAATTCAAAAGATAATCACGCGTTCCGTAGTCTTTTCCATACTTTTGGTTT
CGGGTTTTGGGATATTCAACATAATAATGATGACAGTGATGGAAAAGCGAAGGGAAATAGCGATTCTAAAGGCTATGGGC
TACGAAAAGAGGGATTTAATCCTCATCTTTACCCTTCAGGGACTCATCATAGGACTCTTGGGCGGTATCCTCGGAAACAT
CCTTGCCTACGGAATGCTTGAGTGGCTCGAAACCCTAAGGATAGAAGTTGAGGGAATTATCAGAGCGAAGGGTTTTATCC
TTGACAGGAGTTTGTGGTATCACTTCTTCGGTTTTGTGTTTGCGCTCCTCACCTCTTACCTTGCCTCCTTTTATCCCGCA
TACAGGGCTTCAAAGTTCCATCCCGTGGAGGTCTTCAGAAGCGGTGGCTGA

Upstream 100 bases:

>100_bases
GGAAAATCATCGATAAGACTATAAAACTCGGTGAAACTTACGGGGACAAAGTGGAAGTCCTTGAAGGTTTGAAAGAAGGC
GACAGGATAGTGATTGAGAA

Downstream 100 bases:

>100_bases
GATACTGAGGGCTGAAAACATCAAAAAAGTTATAAGGGGATACGAGATATTGAAGGGTATAAGCCTGAGCGTAAAGAAGG
GGGAATTTGTGAGCATAATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MRAVLFLSFKFFVERKRQSFIATLGVMIGTTAYIVMSSMVNGFQKYFLEEALNINGHVKIFVEAREKGESFLKKFFPDKN
FKILGEKPEETKDKIANYREILRKYSQDKNVIGITVHLIGNGVLTYGVKEKPATFVGIIPKLEDKTLNVSKYLQEGRLNE
LERNKDYVILGIKLAQELGIRETGKKVLLYAPSGEVYRLKVIDFLNTGITEIDKSRIYLHIKKLQDILERQGEVNEVVLK
LKDPDLAPFYAEKLSRETGYKAESWQESFKNFLSIFKIQKIITRSVVFSILLVSGFGIFNIIMMTVMEKRREIAILKAMG
YEKRDLILIFTLQGLIIGLLGGILGNILAYGMLEWLETLRIEVEGIIRAKGFILDRSLWYHFFGFVFALLTSYLASFYPA
YRASKFHPVEVFRSGG

Sequences:

>Translated_416_residues
MRAVLFLSFKFFVERKRQSFIATLGVMIGTTAYIVMSSMVNGFQKYFLEEALNINGHVKIFVEAREKGESFLKKFFPDKN
FKILGEKPEETKDKIANYREILRKYSQDKNVIGITVHLIGNGVLTYGVKEKPATFVGIIPKLEDKTLNVSKYLQEGRLNE
LERNKDYVILGIKLAQELGIRETGKKVLLYAPSGEVYRLKVIDFLNTGITEIDKSRIYLHIKKLQDILERQGEVNEVVLK
LKDPDLAPFYAEKLSRETGYKAESWQESFKNFLSIFKIQKIITRSVVFSILLVSGFGIFNIIMMTVMEKRREIAILKAMG
YEKRDLILIFTLQGLIIGLLGGILGNILAYGMLEWLETLRIEVEGIIRAKGFILDRSLWYHFFGFVFALLTSYLASFYPA
YRASKFHPVEVFRSGG
>Mature_416_residues
MRAVLFLSFKFFVERKRQSFIATLGVMIGTTAYIVMSSMVNGFQKYFLEEALNINGHVKIFVEAREKGESFLKKFFPDKN
FKILGEKPEETKDKIANYREILRKYSQDKNVIGITVHLIGNGVLTYGVKEKPATFVGIIPKLEDKTLNVSKYLQEGRLNE
LERNKDYVILGIKLAQELGIRETGKKVLLYAPSGEVYRLKVIDFLNTGITEIDKSRIYLHIKKLQDILERQGEVNEVVLK
LKDPDLAPFYAEKLSRETGYKAESWQESFKNFLSIFKIQKIITRSVVFSILLVSGFGIFNIIMMTVMEKRREIAILKAMG
YEKRDLILIFTLQGLIIGLLGGILGNILAYGMLEWLETLRIEVEGIIRAKGFILDRSLWYHFFGFVFALLTSYLASFYPA
YRASKFHPVEVFRSGG

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=428, Percent_Identity=22.6635514018692, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787362, Length=419, Percent_Identity=23.1503579952267, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47794; Mature: 47794

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLFLSFKFFVERKRQSFIATLGVMIGTTAYIVMSSMVNGFQKYFLEEALNINGHVKI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FVEAREKGESFLKKFFPDKNFKILGEKPEETKDKIANYREILRKYSQDKNVIGITVHLIG
EEEEHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEC
NGVLTYGVKEKPATFVGIIPKLEDKTLNVSKYLQEGRLNELERNKDYVILGIKLAQELGI
CCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCHHHHCCCCEEEEEEHHHHHCCC
RETGKKVLLYAPSGEVYRLKVIDFLNTGITEIDKSRIYLHIKKLQDILERQGEVNEVVLK
CCCCCEEEEECCCCCEEEEEEHHHHHCCHHHHCCCHHEEEHHHHHHHHHCCCCHHHEEEE
LKDPDLAPFYAEKLSRETGYKAESWQESFKNFLSIFKIQKIITRSVVFSILLVSGFGIFN
ECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IIMMTVMEKRREIAILKAMGYEKRDLILIFTLQGLIIGLLGGILGNILAYGMLEWLETLR
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEVEGIIRAKGFILDRSLWYHFFGFVFALLTSYLASFYPAYRASKFHPVEVFRSGG
HHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MRAVLFLSFKFFVERKRQSFIATLGVMIGTTAYIVMSSMVNGFQKYFLEEALNINGHVKI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FVEAREKGESFLKKFFPDKNFKILGEKPEETKDKIANYREILRKYSQDKNVIGITVHLIG
EEEEHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEC
NGVLTYGVKEKPATFVGIIPKLEDKTLNVSKYLQEGRLNELERNKDYVILGIKLAQELGI
CCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCHHHHCCCCEEEEEEHHHHHCCC
RETGKKVLLYAPSGEVYRLKVIDFLNTGITEIDKSRIYLHIKKLQDILERQGEVNEVVLK
CCCCCEEEEECCCCCEEEEEEHHHHHCCHHHHCCCHHEEEHHHHHHHHHCCCCHHHEEEE
LKDPDLAPFYAEKLSRETGYKAESWQESFKNFLSIFKIQKIITRSVVFSILLVSGFGIFN
ECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IIMMTVMEKRREIAILKAMGYEKRDLILIFTLQGLIIGLLGGILGNILAYGMLEWLETLR
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEVEGIIRAKGFILDRSLWYHFFGFVFALLTSYLASFYPAYRASKFHPVEVFRSGG
HHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]